Displaying drugs 11851 - 11875 of 13061 in total
Octamoxin
Octamoxin, also known as 2-octylhydrazine, is both an irreversible and nonselective monoamine oxidase enzyme inhibitor (MAOI) of the hydrazine chemical class. This drug was used in the past as an antidepressant agent in the 1960s, however, has since been discontinued.
Withdrawn
Matched Synonyms: … 2-octylhydrazine …
Matched Iupac: … (octan-2-yl)hydrazine …
Matched Iupac: … (octan-2-yl)hydrazine …
Evogliptin
Evogliptin has been used in trials studying the treatment and screening of Osteoporosis, Renal Impairment, Type 2 Diabetes Mellitus, Diabetes Mellitis Type 2, and Diabetes Mellitus, Type 2.
Investigational
Matched Iupac: … (3R)-4-[(3R)-3-amino-4-(2,4,5-trifluorophenyl)butanoyl]-3-[(tert-butoxy)methyl]piperazin-2-one …
Matched Description: … Diabetes Mellitus, Diabetes Mellitis Type 2, and Diabetes Mellitus, Type 2. ... has been used in trials studying the treatment and screening of Osteoporosis, Renal Impairment, Type 2 …
Matched Categories: … Dipeptidyl Peptidase 4 ... Heterocyclic Compounds, 1-Ring …
Matched Description: … Diabetes Mellitus, Diabetes Mellitis Type 2, and Diabetes Mellitus, Type 2. ... has been used in trials studying the treatment and screening of Osteoporosis, Renal Impairment, Type 2 …
Matched Categories: … Dipeptidyl Peptidase 4 ... Heterocyclic Compounds, 1-Ring …
Tifcemalimab
Tifcemalimab is under investigation in clinical trial NCT06095583 (Phase 3 Study of Toripalimab Alone or in Combination With Tifcemalimab as Consolidation Therapy in Patients With Limited-stage Small Cell Lung Cancer (LS-SCLC)).
Investigational
Matched Synonyms: … Immunoglobulin g4, anti-(human b and t lymphocyte attenuator (btla)) (human-mus musculus monoclonal js004 .gamma.4- …
Matched Description: … Tifcemalimab is under investigation in clinical trial NCT06095583 (Phase 3 Study of Toripalimab Alone …
Matched Description: … Tifcemalimab is under investigation in clinical trial NCT06095583 (Phase 3 Study of Toripalimab Alone …
Adipiplon
Adipiplon is an nonbenzodiazepine anxiolytic developed by Neurogen Corporation. It is known by the standardized identifier NG2-73.
Investigational
Matched Iupac: … 3-fluoro-2-[1-({2-methyl-8-propyl-[1,2,4]triazolo[1,5-c]pyrimidin-7-yl}methyl)-1H-imidazol-2-yl]pyridine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Surufatinib
Surufatinib is under investigation in clinical trial NCT02588170 (Phase III Study of Surufatinib in Treating Advanced Extrapancreatic Neuroendocrine Tumors).
Investigational
Matched Iupac: … N-[2-(dimethylamino)ethyl]-1-[3-({4-[(2-methyl-1H-indol-5-yl)oxy]pyrimidin-2-yl}amino)phenyl]methanesulfonamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
Epratuzumab
Epratuzumab is a humanized monoclonal antibody derived from the murine IG2a monoclonal antibody, LL2 (EPB-2). This agent may subsequently be well matched for use in oncology and the treatment of inflammatory autoimmune disorders, such as lupus.
Investigational
Matched Description: … Epratuzumab is a humanized monoclonal antibody derived from the murine IG2a monoclonal antibody, LL2 (EPB-2) …
Polysorbate 60
Experimental
3,5,6,8-Tetramethyl-N-Methyl Phenanthrolinium
Experimental
Matched Iupac: … 1,3,5,6,8-pentamethyl-1,10-phenanthrolin-1-ium …
Tetraethylammonium
Tetraethylammonium is an experimental drug with no approved indication or marketed formulation. The only marketed drug containing tetraethylammonium was a combination drug called Fosglutamina B6, but this drug has now been discontinued. As an experimental agent, tetraethylammonium is used in its salt forms such as tetraethylammonium chloride and tetraethylammonium bromide....
Experimental
Investigational
Matched Categories: … MATE 1 Substrates ... MATE 2 Substrates …
Bentazepam
Experimental
Matched Iupac: … 14-phenyl-8-thia-10,13-diazatricyclo[7.5.0.0^{2,7}]tetradeca-1(9),2(7),13-trien-11-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
MK-0893
MK0893 has been used in trials studying the treatment of Type 2 Diabetes Mellitus and Diabetes Mellitus, Type 2.
Investigational
Matched Iupac: … 3-({4-[(1S)-1-[3-(3,5-dichlorophenyl)-5-(6-methoxynaphthalen-2-yl)-1H-pyrazol-1-yl]ethyl]phenyl}formamido …
Matched Description: … , Type 2. ... MK0893 has been used in trials studying the treatment of Type 2 Diabetes Mellitus and Diabetes Mellitus …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Description: … , Type 2. ... MK0893 has been used in trials studying the treatment of Type 2 Diabetes Mellitus and Diabetes Mellitus …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Tyvelose
Experimental
Crovalimab
Crovalimab is under investigation in clinical trial NCT03157635 (Study to Assess Safety, Efficacy, Pharmacokinetics, and Pharmacodynamics of Crovalimab in Healthy Volunteers and Participants With Paroxysmal Nocturnal Hemoglobinuria).
Investigational
2-[(Dioxidophosphoranyl)oxy]benzoate
Experimental
Matched Name: … 2-[(Dioxidophosphoranyl)oxy]benzoate …
Matched Iupac: … 2-[(oxidophosphonoyl)oxy]benzoate …
Matched Iupac: … 2-[(oxidophosphonoyl)oxy]benzoate …
Fluocortolone caproate
Experimental
Matched Iupac: … 4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl]-2-oxoethyl hexanoate ... 2-[(1S,2R,3aS,3bS,5S,9aR,9bS,10S,11aS)-5-fluoro-10-hydroxy-2,9a,11a-trimethyl-7-oxo-1H,2H,3H,3aH,3bH, …
2-Phenylamino-Ethanesulfonic Acid
Experimental
Matched Name: … 2-Phenylamino-Ethanesulfonic Acid …
Matched Iupac: … 2-(phenylamino)ethane-1-sulfonic acid …
Matched Iupac: … 2-(phenylamino)ethane-1-sulfonic acid …
Tecadenoson
Tecadenoson is a novel selective A1 adenosine receptor agonist that is currently being evaluated for the conversion of paroxysmal supraventricular tachycardia (PSVT) to sinus rhythm. It is being developed by CV Therapeutics, Inc.
Investigational
Matched Iupac: … (2R,3S,4R,5R)-2-(hydroxymethyl)-5-(6-{[(3R)-oxolan-3-yl]amino}-9H-purin-9-yl)oxolane-3,4-diol …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
Theralizumab
Theralizumab is a humanized anti-CD28 monoclonal antibody designed for treating autoimmune diseases and cancer. After the first human trial, it was withdrawn due to severe toxicity (likely due to lymphopenia and human cytokine release).[A216527,A216532]
Investigational
Zorubicin
Zorubicin is a drug of the anthracycline class - a class of medications that have historically demonstrated effective chemotherapy for a variety of cancer types.
Experimental
Matched Synonyms: … Benzoic acid hydrazide, 3-hydrazone with daunorubicin …
Matched Iupac: … N'-{1-[(2S,4S)-4-{[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy}-2,5,12-trihydroxy-7-methoxy ... -6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-2-yl]ethylidene}benzohydrazide …
Matched Salts cas: … 36508-71-1 …
Matched Iupac: … N'-{1-[(2S,4S)-4-{[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy}-2,5,12-trihydroxy-7-methoxy ... -6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-2-yl]ethylidene}benzohydrazide …
Matched Salts cas: … 36508-71-1 …
Clostebol acetate
Experimental
Matched Synonyms: … 4-Chlorotestosterone acetate …
Matched Iupac: … 9a,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1- …
Matched Iupac: … 9a,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1- …
Acetorphine
Experimental
Illicit
Matched Synonyms: … 7alpha-etorphine 3-acetate …
Matched Iupac: … (1R,2R,6S,14R,15R,19R)-19-[(2R)-2-hydroxypentan-2-yl]-15-methoxy-3-methyl-13-oxa-3-azahexacyclo[13.2.2.1²,⁸.0¹,⁶.0⁶,¹⁴.0⁷,¹² …
Matched Iupac: … (1R,2R,6S,14R,15R,19R)-19-[(2R)-2-hydroxypentan-2-yl]-15-methoxy-3-methyl-13-oxa-3-azahexacyclo[13.2.2.1²,⁸.0¹,⁶.0⁶,¹⁴.0⁷,¹² …
D-Lactic acid
A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
Experimental
Matched Synonyms: … D-2-Hydroxypropanoic acid ... D-2-Hydroxypropionic acid …
Matched Iupac: … (2R)-2-hydroxypropanoic acid …
Matched Iupac: … (2R)-2-hydroxypropanoic acid …
BBIBP-CorV
BBIBP-CorV vaccine contains a SARS-CoV-2 strain inactivated inside Vero Cells. Investigation shows this vaccine induces neutralizing antibodies in several mammalian species while also showing protective efficacy with SARS-CoV-2 challenge in rhesus macaques . As of August 2020, this vaccine is being tested for prophylaxis against COVID-19 in human clinical trials.
Investigational
Matched Synonyms: … Purified inactivated SARS-CoV-2 Vaccine …
Matched Description: … BBIBP-CorV vaccine contains a SARS-CoV-2 strain inactivated inside Vero Cells. ... neutralizing antibodies in several mammalian species while also showing protective efficacy with SARS-CoV-2 …
Matched Description: … BBIBP-CorV vaccine contains a SARS-CoV-2 strain inactivated inside Vero Cells. ... neutralizing antibodies in several mammalian species while also showing protective efficacy with SARS-CoV-2 …
4-Imidazolmethylene-5-Imidazolone Chromophore
Experimental
Matched Name: … 4-Imidazolmethylene-5-Imidazolone Chromophore …
Matched Iupac: … 2-[(2S)-2-[(1R)-1-amino-2-hydroxyethyl]-4-[(1H-imidazol-5-yl)methyl]-5-oxo-2,5-dihydro-1H-imidazol-1- …
Matched Iupac: … 2-[(2S)-2-[(1R)-1-amino-2-hydroxyethyl]-4-[(1H-imidazol-5-yl)methyl]-5-oxo-2,5-dihydro-1H-imidazol-1- …
8-oxo-dGMP
Experimental
Matched Synonyms: … 2'-deoxy-7,8-dihydro-8-oxo-5'-guanylic acid ... 8-oxo-2'-deoxyguanosine-5'-monophosphate ... 2'-deoxy-7,8-dihydro-8-oxoguanosine 5'-monophosphate …
Matched Iupac: … {[(2R,3S,5R)-5-(6,8-dihydroxy-2-imino-3,9-dihydro-2H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy}phosphonic …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … {[(2R,3S,5R)-5-(6,8-dihydroxy-2-imino-3,9-dihydro-2H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy}phosphonic …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Displaying drugs 11851 - 11875 of 13061 in total