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Displaying drugs 1176 - 1200 of 1832 in total
Brimonidine is an alpha-adrenergic agonist and 2-imidazoline derivative that was first introduced in 1996. It is considered to be a third generation alpha-2 aadrenergic receptor agonist, since it displays preferential binding at alpha-2 adrenoceptors over alpha-1 receptors. Brimonidine displays a higher selectivity toward the alpha-2 adrenergic receptors than clonidine or...
Approved
Matched Description: … Brimonidine is an alpha-adrenergic agonist and 2-imidazoline derivative that was first introduced in ... Early treatment and management of glaucoma, which predominantly involves the lowering of intraocular ... Ophthalmically, brimonidine is used to lower intraocular pressure by reducing aqueous humor production and
Matched Mixtures name: … Brimonidine Tartrate and Timolol Maleate ... BRIMONIDINE TARTRATE and TIMOLOL MALEATE ... Brimonidine Tartrate and Timolol Maleate …
Matched Categories: … Antiglaucoma Preparations and Miotics ... Decongestants and Antiallergics ... Skin and Mucous Membrane Agents ... Adrenergic alpha-Agonists ... Adrenergic alpha-2 Receptor Agonists …
Matched Products: … Dom-brimonidine ... Alpha-Vision sine 2 mg/ml Augentropfen, Lösung im Einzeldosisbehältnis ... TARTRATO DE BRIMONIDINA0.2 % …
Buclizine is an antihistamine medication with both antiemetic and anticholinergic effects , belonging to the piperazine derivative family of drugs. It was manufactured by Stuart Pharms and initially approved by the FDA in 1957. Following this, it was touted to be effective as an appetite stimulant in children when administered...
Approved
Matched Synonyms: … 1-(p-tert-Butylbenzyl)-4-(4-chloro-alpha-phenylbenzyl)piperazine …
Matched Description: … in the treatment of nausea and vomiting during pregnancy. ... It was manufactured by Stuart Pharms and initially approved by the FDA in 1957. ... Buclizine is an antihistamine medication with both antiemetic and anticholinergic effects [L6220], belonging …
Investigational
Matched Synonyms: … .,5.alpha.,17e)- …
Investigational
Matched Synonyms: … 1,4)thiazepine-8-carboxamide, 10,11-dihydro-11-oxo-n-((2-(trifluoromethyl)-5-thiazolyl)methyl)-, 5,5-dioxide
4-Amino-5-cyano-7-(D-ribofuranosyl)-7H- pyrrolo(2,3-d)pyrimidine. Antibiotic antimetabolite isolated from Streptomyces toyocaensis cultures. It is an analog of adenosine, blocks RNA synthesis and ribosome function, and is used mainly as a tool in biochemistry.
Experimental
Matched Synonyms: … 4-amino-5-cyano-7-(D-ribofuranosyl)-7H-pyrrolo(2,3-d)pyrimidine …
Matched Iupac: … 4-amino-7-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile …
Matched Description: … It is an analog of adenosine, blocks RNA synthesis and ribosome function, and is used mainly as a tool ... 4-Amino-5-cyano-7-(D-ribofuranosyl)-7H- pyrrolo(2,3-d)pyrimidine. …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Diamorphine (heroin) is a narcotic analgesic that may be habit-forming. It is a controlled substance (opium derivative) listed in the U.S. Code of Federal Regulations, Title 21 Parts 329.1, 1308.11 (1987). Sale is forbidden in the United States by Federal statute. (Merck Index, 11th ed) Internationally, diamorphine is controlled under...
Approved
Illicit
Investigational
Matched Synonyms: … 7,8-Dihydro-4,5-alpha-epoxy-17-methylmorphinan-3,6-alpha-diol diacetate …
Matched Iupac: … methyl-12-oxa-4-azapentacyclo[9.6.1.0^{1,13}.0^{5,17}.0^{7,18}]octadeca-7(18),8,10,15-tetraen-14-yl acetate
Matched Description: … As heroin, it is illegal to manufacture, possess, or sell in the United States and the UK. ... (Merck Index, 11th ed) Internationally, diamorphine is controlled under Schedules I and IV of the Single …
Experimental
Matched Name: … 3'-O-N-Octanoyl-a-D-Glucopyranosyl-B-D-Fructofuranoside …
Matched Iupac: … 4S,5R)-3,4-dihydroxy-2,5-bis(hydroxymethyl)oxolan-2-yl]oxy}-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl octanoate
Refractory anaplastic astrocytoma (WHO grade III) and Glioblastoma multiforme (WHO grade IV) are primary malignant brain tumours with poor prognosis and limited treatment options. Despite considerable genetic heterogeneity, these tumours often have impaired DNA repair systems, rendering them initially sensitive to alkylating agents, although they invariably develop resistance to these...
Approved
Investigational
Matched Synonyms: … 8-carbamoyl-3-methylimidazo(5,1-d)-1,2,3,5-tetrazin-4(3H)-one ... 3,4-dihydro-3-methyl-4-oxoimidazo(5,1-d)-as-tetrazine-8-carboxamide ... 3-methyl-4-oxo-3,4-dihydroimidazo(5,1-d)(1,2,3,5)tetrazine-8-carboxamide …
Matched Iupac: … 3-methyl-4-oxo-3H,4H-imidazo[4,3-d][1,2,3,5]tetrazine-8-carboxamide …
Matched Description: … guanine bases leading to DNA lesions and eventual apoptosis. ... malignant brain tumours with poor prognosis and limited treatment options. ... Refractory anaplastic astrocytoma (WHO grade III) and Glioblastoma multiforme (WHO grade IV) are primary …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Experimental
Matched Synonyms: … alpha-Amino-epsilon-hydroxycaproic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins …
An organic compound used often as a reagent in organic synthesis, as a flavoring agent, and in tanning. It has been demonstrated as an intermediate in the metabolism of acetone and its derivatives in isolated cell preparations, in various culture media, and in vivo in certain animals. [PubChem]
Experimental
Matched Synonyms: … alpha-ketopropionaldehyde …
Matched Description: … It has been demonstrated as an intermediate in the metabolism of acetone and its derivatives in isolated ... An organic compound used often as a reagent in organic synthesis, as a flavoring agent, and in tanning ... cell preparations, in various culture media, and in vivo in certain animals. …
Cyclobenzaprine, a centrally-acting muscle relaxant, was first synthesized in 1961 and has been available for human use since 1977. It was initially studied for use as antidepressant given its structural similarity to tricyclic antidepressants - it differs from Amitriptyline by only a single double bond.[A185039,A184982] Since its approval, it has...
Approved
Matched Synonyms: … (3-Dibenzo[a,d]cyclohepten-5-ylidene-propyl)-dimethyl-amine ... N,N-dimethyl-5H-dibenzo(a,d)cycloheptene-Δ5,γ-propylamine …
Matched Description: … Cyclobenzaprine, a centrally-acting muscle relaxant, was first synthesized in 1961[A185039] and has been …
Matched Products: … Dom-cyclobenzaprine …
Experimental
Matched Name: … 2-(cycloheptylmethyl)-1,1-dioxido-1-benzothiophen-6-yl sulfamate …
Amphetamine, a compound discovered over 100 years ago, is one of the more restricted controlled drugs. It was previously used for a large variety of conditions and this changed until this point where its use is highly restricted. Amphetamine, with the chemical formula alpha-methylphenethylamine, was discovered in 1910 and first...
Approved
Illicit
Investigational
Matched Synonyms: … alpha-Methylbenzeneethaneamine ... (+-)-alpha-Methylphenylethylamine …
Matched Description: … Amphetamine, with the chemical formula alpha-methylphenethylamine, was discovered in 1910 and first synthesized ... After being proven to reduce drug-induced anesthesia and produce arousal and insomnia, amphetamine racemic ... Amphetamine structure presents one chiral center and it exists in the form of dextro- and levo-isomers …
Matched Mixtures name: … Dextroamphetamine Saccharate, Amphetamine Aspartate, Dextroamphetamine Sulfate, and Amphetamine Sulfate ... Dextroamphetamine Saccharate and Amphetamine Aspartate and Dextroamphetamine Sulfate and Amphetamine ... Dextroamphetamine Saccharate and Amphetamine Aspartate and Dextroamphetamine Sulfate and Amphetamine …
Matched Categories: … Psychostimulants, Agents Used for ADHD and Nootropics …
Experimental
Matched Name: … 5-(4-METHOXYBIPHENYL-3-YL)-1,2,5-THIADIAZOLIDIN-3-ONE 1,1-DIOXIDE
Experimental
Matched Synonyms: … N-alpha-L-acetyl-arginine …
Matched Categories: … Amino Acids, Peptides, and Proteins …
An inhibitor of the enzyme tyrosine 3-monooxygenase, and consequently of the synthesis of catecholamines. It is used to control the symptoms of excessive sympathetic stimulation in patients with pheochromocytoma. (Martindale, The Extra Pharmacopoeia, 30th ed)
Approved
Matched Synonyms: … (S)-alpha-Methyltyrosine ... (-)-alpha-Methyl-L-tyrosine …
Matched Description: … An inhibitor of the enzyme tyrosine 3-monooxygenase, and consequently of the synthesis of catecholamines …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Auranofin is a gold salt that is capable of eliciting pharmacologic actions that suppress inflammation and stimulate cell-mediated immunity. It has subsequently been listed by the World Health Organization as a member of the antirheumatic agent category. Auranofin appears to induce heme oxygenase 1 (HO-1) mRNA. Heme oxygenase 1 is...
Approved
Investigational
Matched Synonyms: … (1-Thio-beta-D-glucopyranosato)(triethylphosphine)gold 2,3,4,6-tetraacetate ... 2,3,4,6-Tetra-O-acetyl-1-thio-beta-D-glucopyranosato-S (triethylphosphine)gold …
Matched Iupac: … ,5R,6S)-3,4,5-tris(acetyloxy)-6-{[(triethyl-lambda5-phosphanylidene)aurio]sulfanyl}oxan-2-yl]methyl acetate
Matched Description: … Auranofin is a gold salt that is capable of eliciting pharmacologic actions that suppress inflammation and
Matched Categories: … Antiinflammatory and Antirheumatic Products …
Kanamycin (also known as kanamycin A) is an aminoglycoside bacteriocidal antibiotic, available in oral, intravenous, and intramuscular forms, and used to treat a wide variety of infections. Kanamycin is isolated from the bacterium Streptomyces kanamyceticus and its most commonly used form is kanamycin sulfate.
Approved
Investigational
Vet approved
Matched Synonyms: … 4,6-diamino-2-hydroxy-1,3-cyclohexane 3,6'diamino-3,6'-dideoxydi-α-D-glucoside ... 4,6-diamino-2-hydroxy-1,3-cyclohexylene 3,6'-diamino-3,6'-dideoxydi-D-glucopyranoside …
Matched Description: … intramuscular forms, and used to treat a wide variety of infections. ... known as kanamycin A) is an aminoglycoside bacteriocidal antibiotic, available in oral, intravenous, and ... Kanamycin is isolated from the bacterium Streptomyces kanamyceticus and its most commonly used form is …
Matched Categories: … Alimentary Tract and Metabolism …
Thyrotropin alfa is a recombinant form of thyroid stimulating hormone used in performing certain tests in patients who have or have had thyroid cancer. It is also used along with a radioactive agent to destroy remaining thyroid tissue in certain patients who have had their thyroid gland removed because of...
Approved
Vet approved
Matched Synonyms: … Thyrotropin alpha
Matched Description: … (hCG), luteinizing hormone (LH), and follicle-stimulating hormone (FSH). ... of 92 amino acid residues containing two N-linked glycosylation sites and a beta subunit of 112 residues ... The beta subunit (TSHB) bestows its receptor specificity due to the uniqueness to TSH. …
Matched Categories: … Pituitary and Hypothalamic Hormones and Analogues ... Sex Hormones and Insulins ... Anterior Pituitary Lobe Hormones and Analogues ... Hormones, Hormone Substitutes, and Hormone Antagonists …
AMPA is a specific agonist for the AMPA receptor.
Experimental
Matched Synonyms: … (S)-alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid …
Altrenogest, also known as allyltrenbolone, is a steroidal progestin that is widely used in veterinary medicine to suppress estrus in animals.
Vet approved
Matched Synonyms: … 17-alpha-Allyl-estratriene-4,9,11,17-beta-ol-3-one …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Investigational
Matched Synonyms: … Recombinant human highly phosphorylated alpha-L-iduronidase …
2'-cyano-2'-deoxy-1-(beta-D-arabinofuranosyl)cytosine has been used in trials studying the treatment of Advanced Colorectal Cancer.
Investigational
Matched Synonyms: … 2'-cyano-2'-deoxy-1-(beta-D-arabinofuranosyl)cytosine …
Matched Description: … 2'-cyano-2'-deoxy-1-(beta-D-arabinofuranosyl)cytosine has been used in trials studying the treatment …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Dextropropoxyphene is an opioid analgesic manufactured by Eli Lilly and Company. It is used in the symptomatic treatment of mild pain. It displays antitussive and local anaesthetic actions. Due to the risk of cardiac arrhythmias and overdose, possibly leading to death, dextropropoxyphene has been withdrawn from the market in Europe...
Approved
Illicit
Investigational
Withdrawn
Matched Synonyms: … d-Propoxyphene …
Matched Description: … Due to the risk of cardiac arrhythmias and overdose, possibly leading to death, dextropropoxyphene has ... It displays antitussive and local anaesthetic actions. ... Dextropropoxyphene is an opioid analgesic manufactured by Eli Lilly and Company. …
Matched Mixtures name: … Propoxyphene Hydrochloride and Acetaminophen ... Propoxyphene Napsylate and Acetominophen ... Propoxyphene and Acetaminophen …
Experimental
Matched Synonyms: … 6-O-phosphono-β-D-galactopyranose …
Matched Name: … beta-D-galactose 6-phosphate …
Displaying drugs 1176 - 1200 of 1832 in total