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Displaying drugs 11976 - 12000 of 12106 in total
PF-07304814 is a small molecule prodrug that targets the 3CLpro protease (Mpro), which is used by viruses like SARS-CoV-2 to assemble and multiply . Once administered through intravenous infusion, the compound is cleaved into PF-00835231 to exert its anti-viral effects . PF-07304814, developed by Pfizer, was first identified during the...
Investigational
Matched Description: … PF-07304814 is a small molecule prodrug that targets the 3CLpro protease (Mpro) ... Phase 1b studies are also exploring the safety and tolerability of PF-07304814 in COVID-19 patients who …
Investigational
Boron (B) is a chemical element with an atomic number 5 that belongs in the Period 2 and Group 13 in the periodic table. It is a low-abundant metalloid that is a poor electrical conductor at room temperature. Natural boron exists in 2 stable isotopes however pure boron is hard...
Experimental
Matched Description: … agents, insecticides, semiconductors, magnets, wood preservatives, and an additive in glass fibers of ... It is a low-abundant metalloid that is a poor electrical conductor at room temperature. ... Boron (B) is a chemical element with an atomic number 5 that belongs in the Period 2 and Group 13 in …
Tabelecleucel is an innovative therapy that uses Epstein-Barr virus (EBV)-specific allogeneic cytotoxic T cells (CTLs). It is produced by mixing T-cells with B-cells that have been infected with the Epstein-Barr virus (EBV). Both T-cells and B-cells are obtained from the same donor, and T-cells are grown to increase their numbers....
Investigational
Matched Description: … When given to a patient with EBV-associated post-transplant lymphoproliferative disorder (PTLD) following ... for Human Use (CHMP) recommended tabelecleucel be granted marketing authorization for the treatment of
CA-074 methyl ester (CA-074Me) is a cell-permeable cathepsin B inhibitor. It is converted by cellular esterases to CA-074.[A258234,A258239]
Experimental
Matched Description: … CA-074 methyl ester (CA-074Me) is a cell-permeable cathepsin B inhibitor. …
CGC-11047 is a polyamine analog designed to halt cell growth and induce apoptosis.
Investigational
Matched Description: … CGC-11047 is a polyamine analog designed to halt cell growth and induce apoptosis. …
Investigational
MYO-029 is a human anti-GDF-8 monoclonal antibody, which is being developed to treat muscle-wasting diseases including muscular dystrophy and age-related sarcopenia.
Investigational
Matched Description: … MYO-029 is a human anti-GDF-8 monoclonal antibody, which is being developed to treat muscle-wasting diseases …
Investigational
Cambinol is a beta-naphtol derivative that inhibits NAD-dependant deacetylases to reduce cell survival under stress. This activity is currently being investigated for its use as a cancer treatment.
Experimental
Matched Description: … This activity is currently being investigated for its use as a cancer treatment. ... Cambinol is a beta-naphtol derivative that inhibits NAD-dependant deacetylases to reduce cell survival …
E-2012 is a gamma secretase modulator that is being evaluated as a potential new treatment for Alzheimer's disease.
Investigational
Matched Description: … E-2012 is a gamma secretase modulator that is being evaluated as a potential new treatment for Alzheimer's …
Bimoclomol is an investigational drug that induces stress proteins and has cytoprotective effects.
Investigational
Investigational
Bioymifi is a small molecule that acts as a tumor necrosis factor-related apoptosis-induced ligand (TRAIL) mimetic. Upon binding to the death receptor 5 (DR5) on cancer cells, bioymifi triggers apoptosis, possibly through a caspase-dependent pathway. Bioymifi is currently being investigated as an anti-tumor agent.[A257048,A257053]
Investigational
Matched Description: … Bioymifi is a small molecule that acts as a tumor necrosis factor-related apoptosis-induced ligand (TRAIL ... binding to the death receptor 5 (DR5) on cancer cells, bioymifi triggers apoptosis, possibly through a
TRC093 is a recombinant humanized IgG1k monoclonal antibody.
Investigational
Matched Description: … TRC093 is a recombinant humanized IgG1k monoclonal antibody. …
Tangerine peel is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Description: … Tangerine peel is a plant/plant extract used in some OTC (over-the-counter) products. …
Experimental
Descartes-30 is an RNA-engineered off-the-shelf allogeneic mesenchymal stem cell (MSC) product developed by Cartesian Therapeutics. The RNA-engineering is performed with Cartesian Therapeutics’ proprietary RNA Armory which is a platform that activates and provides cells with mRNA-based therapeutics.
Investigational
Matched Description: … L27531] The RNA-engineering is performed with Cartesian Therapeutics’ proprietary RNA Armory which is a
Talmapimod is the first-generation oral p38 MAP kinase inhibitor developed by Scios. It has shown to be effective to cure inflammatory diseases such as Rheumatoid Arthritis.
Investigational
Schisandra chinensis fruit is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Description: … Schisandra chinensis fruit is a plant/plant extract used in some OTC (over-the-counter) products. …
Ronacaleret is a calcium-sensing receptor antagonist.
Investigational
Matched Description: … Ronacaleret is a calcium-sensing receptor antagonist. …
XL418 is a novel anticancer compound.
Investigational
Matched Description: … XL418 is a novel anticancer compound. …
Lactobacillus is a common bacteria found in the gut with Lactobacillus coryniformis K8 being originally isolated from artisan goat cheese.
Investigational
Matched Description: … Lactobacillus is a common bacteria found in the gut with Lactobacillus coryniformis K8 being originally …
Displaying drugs 11976 - 12000 of 12106 in total