Displaying drugs 12351 - 12375 of 12915 in total
Etripamil
Etripamil has been used in trials studying the treatment of Paroxysmal Supraventricular Tachycardia (PSVT).
Investigational
Matched Iupac: … methyl 3-(2-{[(4S)-4-cyano-4-(3,4-dimethoxyphenyl)-4-(propan-2-yl)butyl](methyl)amino}ethyl)benzoate …
Darglitazone
Experimental
Matched Iupac: … 5-({4-[3-(5-methyl-2-phenyl-1,3-oxazol-4-yl)propanoyl]phenyl}methyl)-1,3-thiazolidine-2,4-dione …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Menaquinone 6
Menaquinone 6 is under investigation in clinical trial NCT01194778 (Comparison of Efficacy of Different Dosages Vitamin K2).
Investigational
Matched Iupac: … 2-[(2E,6E,10E,14E,18E)-3,7,11,15,19,23-hexamethyltetracosa-2,6,10,14,18,22-hexaen-1-yl]-3-methyl-1,4- …
Fallypride
Fallypride is under investigation in clinical trial NCT02310360 (Striatal and Extra-striatal Dopamine Release in Response to Food in Healthy Humans).
Investigational
Matched Iupac: … 5-(3-fluoropropyl)-2,3-dimethoxy-N-{[(2S)-1-(prop-2-en-1-yl)pyrrolidin-2-yl]methyl}benzamide …
Ceralifimod
Ceralifimod is under investigation in clinical trial NCT01226745 (Phase 2 Extension Trial in Patients With Relapsing-remitting Multiple Sclerosis (RRMS)).
Investigational
Matched Iupac: … 1-({6-[(2-methoxy-4-propylphenyl)methoxy]-1-methyl-3,4-dihydronaphthalen-2-yl}methyl)azetidine-3-carboxylic …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Sphingosine 1 Phosphate Receptor Modulators …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Sphingosine 1 Phosphate Receptor Modulators …
Fenretinide
A synthetic retinoid that is used orally as a chemopreventive against prostate cancer and in women at risk of developing contralateral breast cancer. It is also effective as an antineoplastic agent.
Investigational
Matched Iupac: … (2E,4E,6E,8E)-N-(4-hydroxyphenyl)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenamide …
Matched Description: … A synthetic retinoid that is used orally as a chemopreventive against prostate cancer and in women at …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Description: … A synthetic retinoid that is used orally as a chemopreventive against prostate cancer and in women at …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Famphur
Vet approved
Matched Categories: … Compounds used in a research, industrial, or household setting …
Isepamicin
Experimental
Matched Iupac: … (2S)-3-amino-N-[(1R,2S,3S,4R,5S)-5-amino-4-{[(2R,3R,4S,5S,6R)-6-(aminomethyl)-3,4,5-trihydroxyoxan-2- ... yl]oxy}-2-{[(2R,3R,4R,5R)-3,5-dihydroxy-5-methyl-4-(methylamino)oxan-2-yl]oxy}-3-hydroxycyclohexyl]-2 …
Matched Categories: … Drugs that are Mainly Renally Excreted with a Narrow Therapeutic Index …
Matched Categories: … Drugs that are Mainly Renally Excreted with a Narrow Therapeutic Index …
Fenebrutinib
Fenebrutinib is under investigation in clinical trial NCT03174041 (A Drug-Drug Interaction Study Between GDC-0853 and Midazolam, Itraconazole, Rosuvastatin, and Simvastatin).
Investigational
Matched Iupac: … 10-[3'-(hydroxymethyl)-1-methyl-5-({5-[(2S)-2-methyl-4-(oxetan-3-yl)piperazin-1-yl]pyridin-2-yl}amino …
Matched Description: … Fenebrutinib is under investigation in clinical trial NCT03174041 (A Drug-Drug Interaction Study Between …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Description: … Fenebrutinib is under investigation in clinical trial NCT03174041 (A Drug-Drug Interaction Study Between …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Glutathionylspermidine disulfide
Experimental
Matched Iupac: … }carbamoyl)methyl]carbamoyl}ethyl]disulfanyl}-1-{[({3-[(4-aminobutyl)amino]propyl}carbamoyl)methyl]carbamoyl ... (2R)-2-amino-4-{[(1R)-2-{[(2R)-2-[(4R)-4-amino-4-carboxybutanamido]-2-{[({3-[(4-aminobutyl)amino]propyl …
Brecanavir
Brecanavir (VX-385) an orally active aspartic protease inhibitor (PI), under investigation by Vertex and GlaxoSmithKline for the treatment of HIV. In July 2006, Vertex indicated that it expected GSK to initiate phase III trials of the drug in 2007. In December of 2006 GSK announced a decision to discontinue the...
Investigational
Matched Iupac: … (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl N-[(2S,3R)-3-hydroxy-1-{4-[(2-methyl-1,3-thiazol-4-yl)methoxy …
Matched Description: … In December of 2006 GSK announced a decision to discontinue the development of brecanavir for the treatment …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Description: … In December of 2006 GSK announced a decision to discontinue the development of brecanavir for the treatment …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Etheno-Nadp
Experimental
Matched Iupac: … yl}oxolan-3-yl]oxy}phosphonic acid ... 3,4,5-trihydroxyoxolan-2-yl]methoxy})phosphoryl]oxy})phosphoryl]oxy}methyl)-2-{3H-imidazo[2,1-f]purin-3- …
Marimastat
Used in the treatment of cancer, Marmiastat is an angiogenesis and metastasis inhibitor. As an angiogenesis inhibitor it limits the growth and production of blood vessels. As an antimetatstatic agent it prevents malignant cells from breaching the basement membranes.
Investigational
Matched Iupac: … (2S,3R)-N'-[(1S)-2,2-dimethyl-1-(methylcarbamoyl)propyl]-N,2-dihydroxy-3-(2-methylpropyl)butanediamide …
Dorsomorphin
Experimental
Matched Iupac: … 4-(6-{4-[2-(piperidin-1-yl)ethoxy]phenyl}pyrazolo[1,5-a]pyrimidin-3-yl)pyridine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Etozoline
Etozoline is marketed in Europe under the names Diulozin, Elkapin, and Etopinil. Etozoline is a loop diuretic.
Experimental
Matched Iupac: … ethyl 2-[(2Z)-3-methyl-4-oxo-5-(piperidin-1-yl)-1,3-thiazolidin-2-ylidene]acetate …
Matched Description: … Etozoline is a loop diuretic. …
Matched Description: … Etozoline is a loop diuretic. …
Oxaprotiline
Oxaprotiline is a norepinephrine reuptake inhibitor of the tetracyclic antidepressant family that is related to maprotiline. This drug was never marketed. Oxaprotiline is a racemic mixture of the isomers levoprotiline and dextroprotiline. Levoprotiline is the R or levo isomer of oxaprotiline (CGP-12,103-A). Dextroprotiline is the S or dextro isomer of...
Experimental
Matched Iupac: … 1-(methylamino)-3-{tetracyclo[6.6.2.0^{2,7}.0^{9,14}]hexadeca-2,4,6,9,11,13-hexaen-1-yl}propan-2-ol …
Matched Description: … Levoprotiline is the R or levo isomer of oxaprotiline (CGP-12,103-A). ... Dextroprotiline is the S or dextro isomer of oxaprotiline (CGP-12,104-A). ... Oxaprotiline is a racemic mixture of the isomers levoprotiline and dextroprotiline. …
Matched Description: … Levoprotiline is the R or levo isomer of oxaprotiline (CGP-12,103-A). ... Dextroprotiline is the S or dextro isomer of oxaprotiline (CGP-12,104-A). ... Oxaprotiline is a racemic mixture of the isomers levoprotiline and dextroprotiline. …
Icotinib
Icotinib is a potent and specific epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI)
Icotinib was approved in China by the SFDA in June, 2011 and in January 2014, Beta Pharma, Inc. was given a “May Proceed” from the US FDA to conduct a Phase I study for the...
Experimental
Investigational
Matched Iupac: … N-(3-ethynylphenyl)-7H,8H,10H,11H,13H,14H-1,4,7,10-tetraoxacyclododeca[2,3-g]quinazolin-4-amine …
Matched Description: … “May Proceed” from the US FDA to conduct a Phase I study for the evaluation of icotinib as a treatment ... Icotinib is a potent and specific epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor ( ... Icotinib was approved in China by the SFDA in June, 2011 and in January 2014, Beta Pharma, Inc. was given a …
Matched Description: … “May Proceed” from the US FDA to conduct a Phase I study for the evaluation of icotinib as a treatment ... Icotinib is a potent and specific epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor ( ... Icotinib was approved in China by the SFDA in June, 2011 and in January 2014, Beta Pharma, Inc. was given a …
Menatetrenone
Menatetrenone has been used in trials studying the treatment of Diabetes, Osteoporosis, Prediabetic State, and Hepatocellular Carcinoma.
Investigational
Matched Iupac: … 2-methyl-3-[(2E,6E,10E)-3,7,11,15-tetramethylhexadeca-2,6,10,14-tetraen-1-yl]-1,4-dihydronaphthalene- …
SCH-900271
Sch 900271 has been used in trials studying the treatment of Mixed Hyperlipidemia and Primary Hypercholesterolemia.
Investigational
Matched Iupac: … 5-[3-(1-methylcyclopropyl)propyl]-1H,2H,3H,4H,7H-pyrano[2,3-d]pyrimidine-2,4,7-trione …
Mavoglurant
Mavoglurant has been used in trials studying the treatment of Patient Diagnosed With OCD and and Resistant to SSRI Treatment (Failed SSRI Over 12 Weeks at Appropriate Doses).
Investigational
Matched Iupac: … methyl (3aR,4S,7aR)-4-hydroxy-4-[2-(3-methylphenyl)ethynyl]-octahydro-1H-indole-1-carboxylate …
Surinabant
Surinabant has been investigated for the treatment of Smoking Cessation.
Investigational
Matched Iupac: … 5-(4-bromophenyl)-1-(2,4-dichlorophenyl)-4-ethyl-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Piprozolin
Experimental
Matched Iupac: … ethyl 2-[(2Z)-3-ethyl-4-oxo-5-(piperidin-1-yl)-1,3-thiazolidin-2-ylidene]acetate …
Trifluperidol
Experimental
Matched Iupac: … 1-(4-fluorophenyl)-4-{4-hydroxy-4-[3-(trifluoromethyl)phenyl]piperidin-1-yl}butan-1-one …
Branaplam
Branaplam is under investigation in clinical trial NCT02268552 (An Open Label Study of LMI070 (Branaplam) in Type 1 Spinal Muscular Atrophy (SMA)).
Investigational
Matched Iupac: … 5-(1H-pyrazol-4-yl)-2-{6-[(2,2,6,6-tetramethylpiperidin-4-yl)oxy]pyridazin-3-yl}phenol …
Matched Description: … under investigation in clinical trial NCT02268552 (An Open Label Study of LMI070 (Branaplam) in Type 1 …
Matched Description: … under investigation in clinical trial NCT02268552 (An Open Label Study of LMI070 (Branaplam) in Type 1 …
Morinidazole
Morinidazole is under investigation in clinical trial NCT03380793 (A Trial to Assess the Efficacy and Safety of Morinidazole in Patients With Appendicitis).
Investigational
Matched Iupac: … 1-(2-methyl-5-nitro-1H-imidazol-1-yl)-3-(morpholin-4-yl)propan-2-ol …
Matched Description: … Morinidazole is under investigation in clinical trial NCT03380793 (A Trial to Assess the Efficacy and …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Description: … Morinidazole is under investigation in clinical trial NCT03380793 (A Trial to Assess the Efficacy and …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Displaying drugs 12351 - 12375 of 12915 in total