Displaying drugs 101 - 125 of 165 in total
Estriol
A hydroxylated metabolite of estradiol or estrone that has a hydroxyl group at C3-beta, 16-alpha, and 17-beta position. Estriol is a major urinary estrogen. During pregnancy, large amount of estriol is produced by the placenta. Isomers with inversion of the hydroxyl group or groups are called epiestriol. Though estriol is...
Approved
Investigational
Vet approved
Estradiol
Estradiol is a naturally occurring hormone circulating endogenously in females. It is commercially available in several hormone therapy products for managing conditions associated with reduced estrogen, such as vulvovaginal atrophy and hot flashes. Some available forms of estradiol include oral tablets, injections, vaginal rings, transdermal patches, sprays, gels, and creams.[L11485,L11488,L11491,...
Approved
Investigational
Vet approved
Onasemnogene abeparvovec
Onasemnogene abeparvovec is an adeno-associated virus vector-based gene therapy that has been approved by the FDA in May 2019 for the treatment of infant patients (less than 2 years of age) with spinal muscular atrophy (SMA) and a specific mutation in the survival motor neuron 1 (SMN1) gene. SMA is...
Approved
Nuvaxovid
SARS-CoV-2, the causative agent of COVID-19, relies on the interaction between its trimeric spike (S) glycoprotein and angiotensin-converting enzyme 2 (hACE2) expressed on host cells in order to establish a productive infection in humans. Antibodies directed against the S protein are capable of blocking S-hACE2 interactions and neutralizing viral particles...
Approved
Investigational
Salicylic acid
A compound obtained from the bark of the white willow and wintergreen leaves, and also prepared synthetically. It has bacteriostatic, fungicidal, and keratolytic actions. Its salts, the salicylates, are used as analgesics.
Approved
Investigational
Vet approved
Matched Mixtures name: … Bee Venom Wart And Tags Removal Treatment …
Somatotropin
Human growth hormone (HGH), also known as somatotropin, is a peptide hormone that is synthesized and secreted by the somatotropic cells of the anterior pituitary gland. Growth hormone plays an essential role in growth regulation during childhood as well as other basal metabolic functions, muscle and fat mass regulation, blood...
Approved
Investigational
mRNA-3745
mRNA-3745 is a lipid nanoparticle (LNP) encapsulated with nucleoside-modified, codon-optimized mRNAs encoding human glucose 6-phosphatase (G6Pase).
Investigational
Matched Name: … mRNA-3745 …
Matched Description: … mRNA-3745 is a lipid nanoparticle (LNP) encapsulated with nucleoside-modified, codon-optimized mRNAs …
Matched Description: … mRNA-3745 is a lipid nanoparticle (LNP) encapsulated with nucleoside-modified, codon-optimized mRNAs …
mRNA-3705
mRNA-3705 is an investigational mRNA encoding methylmalonic CoA mutase (MUT) enzyme. Developed by Moderna TX Inc., it is being investigated for the treatment of methylmalonic academia.
Investigational
Matched Name: … mRNA-3705 …
Matched Description: … mRNA-3705 is an investigational mRNA encoding methylmalonic CoA mutase (MUT) enzyme. …
Matched Description: … mRNA-3705 is an investigational mRNA encoding methylmalonic CoA mutase (MUT) enzyme. …
mRNA-3351
mRNA-3351 is a modified mRNA encoding the UGT1A1 gene. Developed by Moderna, it is currently being investigated as the treatment for Crigler-Najjar syndrome
Experimental
Matched Name: … mRNA-3351 …
Matched Description: … mRNA-3351 is a modified mRNA encoding the UGT1A1 gene. …
Matched Description: … mRNA-3351 is a modified mRNA encoding the UGT1A1 gene. …
mRNA-3927
mRNA-3927 is an investigational mRNA therapy that consists of two mRNAs that encode for the alpha and beta subunits of the mitochondrial enzyme propionyl-CoA carboxylase (PCC) encapsulated within a lipid nanoparticle (LNP). Developed by Moderna Inc., it is being investigated for the treatment of propionic acidemia.
Investigational
Matched Name: … mRNA-3927 …
Matched Description: … mRNA-3927 is an investigational mRNA therapy that consists of two mRNAs that encode for the alpha and …
Matched Description: … mRNA-3927 is an investigational mRNA therapy that consists of two mRNAs that encode for the alpha and …
mRNA-1345
mRNA-1345 is an investigational RSV vaccine.
Investigational
Matched Name: … mRNA-1345 …
Matched Description: … mRNA-1345 is an investigational RSV vaccine. …
Matched Description: … mRNA-1345 is an investigational RSV vaccine. …
ChulaCov19 mRNA vaccine
The ChulaCov19 vaccine is mRNA-based and was developed in Thailand’s Chulalongkorn University in collaboration with the University of Pennsylvania in the US[L30673, L30678]. Pre-clinical studies in mice and monkeys showed evidence that the vaccine facilitates an impressive generation of neutralizing antibodies . The next phase of this study is for...
Investigational
Matched Name: … ChulaCov19 mRNA vaccine …
Matched Description: … The ChulaCov19 vaccine is mRNA-based and was developed in Thailand’s Chulalongkorn University in collaboration …
Matched Description: … The ChulaCov19 vaccine is mRNA-based and was developed in Thailand’s Chulalongkorn University in collaboration …
SARS-CoV-2 mRNA vaccine
SARS-CoV-2 mRNA vaccine (ARCoV) is a novel mRNA coronavirus vaccine that consists of a lipid nanoparticle-encapsulated mRNA encoding the receptor binding domain of SARS-CoV-2 . It is the first COVID-19 mRNA vaccine to be approved for clinical trials in China, and was co-developed by Abogen Biosciences, Walvax Biotechnolgoy Co., Ltd....
Investigational
Matched Name: … SARS-CoV-2 mRNA vaccine …
Matched Description: … SARS-CoV-2 mRNA vaccine (ARCoV) is a novel mRNA coronavirus vaccine that consists of a lipid nanoparticle-encapsulated ... mRNA encoding the receptor binding domain of SARS-CoV-2[A220048]. ... It is the first COVID-19 mRNA vaccine to be approved for clinical trials in China, and was co-developed …
Matched Description: … SARS-CoV-2 mRNA vaccine (ARCoV) is a novel mRNA coronavirus vaccine that consists of a lipid nanoparticle-encapsulated ... mRNA encoding the receptor binding domain of SARS-CoV-2[A220048]. ... It is the first COVID-19 mRNA vaccine to be approved for clinical trials in China, and was co-developed …
LioCyx-M004
LioCyx-M004 are autologous T cells transduced with a retroviral vector encoding a hepatitis B virus antigen-specific T cell receptor.
Investigational
Matched Synonyms: … mRNA HBV/TCR T-cells …
7-methyl-guanosine-5'-triphosphate-5'-guanosine
Experimental
Matched Synonyms: … mRNA cap analog N7-Methyl GpppG …
CVnCoV
The CVnCov Vaccine (or CV07050101) is in development by CureVac AG. The vaccine uses mRNA technology to create a protein associated with SARS-CoV2, and upon administration and replication, to initiate subsequent immune responses in the body. As of June 2020, the company received regulatory approval from German and Belgian Authorities...
Investigational
Matched Synonyms: … SARS-CoV-2 mRNA vaccine …
Matched Description: … The vaccine uses mRNA technology to create a protein associated with SARS-CoV2, and upon administration …
Matched Description: … The vaccine uses mRNA technology to create a protein associated with SARS-CoV2, and upon administration …
Teprasiran
Teprasiran is under investigation in clinical trial NCT03510897 (QPI-1002 Phase 3 for Prevention of Major Adverse Kidney Events (MAKE) in Subjects at High Risk for AKI Following Cardiac Surgery).
Investigational
Matched Synonyms: … Synthetic double-stranded siRNA oligonucleotide directed against p53 mRNA …
Fitusiran
Fitusiran is under investigation in clinical trial NCT02554773 (An Open-label Extension Study of an Investigational Drug, ALN-AT3SC, in Patients With Moderate or Severe Hemophilia A or B).
Investigational
Matched Synonyms: … Synthetic double-stranded siRNA oligonucleotide against antithrombin mRNA …
VO659
VO659 is an antisense oligonucleotide being investigated for the treatment of Huntington's disease.
Investigational
Matched Synonyms: … oligonucleotide that has been developed to target expanded CAG repeats in messenger ribonucleic acid (mRNA …
Zorevunersen
Investigational
Matched Synonyms: … 18-Mer Antisense Oligonucleotide Complementary To SCN1A mRNA …
NTLA-2002
NTLA-2002 is a lipid nanoparticle encapsulating single guide RNA (G012267) targeting the human KLKB1 gene and messenger RNA (mRNA000042) encoding Cas9. It is an investigational therapy designed to knock out the target gene kallikrein B1 (KLKB1) to reduce plasma kallikrein activity, thereby preventing hereditary angioedema attacks.
Investigational
ARCT-810
ARCT-810 is an mRNA replacement therapy that delivers ornithine transcarbamylase mRNA to hepatocytes.
Investigational
Matched Description: … ARCT-810 is an mRNA replacement therapy that delivers ornithine transcarbamylase mRNA to hepatocytes. …
UX053
UX053 is an mRNA encoding the human glycogen debranching enzyme.
Investigational
Matched Description: … UX053 is an mRNA encoding the human glycogen debranching enzyme. …
Contulakin-G
Contulakin-G is a broad spectrum non-opioid analgesic. It is the synthetic form of a natural peptide extracted from the venom of the Conus Geographus sea snail.
Investigational
Matched Description: … It is the synthetic form of a natural peptide extracted from the venom of the Conus Geographus sea snail …
Displaying drugs 101 - 125 of 165 in total