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Displaying drugs 12576 - 12600 of 12637 in total
Investigational
Matched Iupac: … 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-1,2,4-triazole-3-carboximidamide …
Dovitinib is an orally active small molecule that exhibits potent inhibitory activity against multiple RTKs involved in tumor growth and angiogenesis. Preclinical data show that dovitinib works to inhibit multiple kinases associated with different cancers, including acute myeloid leukemia (AML) and multiple myeloma. Chiron currently has three ongoing Phase I...
Investigational
Matched Iupac: … 4-amino-5-fluoro-3-[6-(4-methylpiperazin-1-yl)-1H-1,3-benzodiazol-2-yl]-1,2-dihydroquinolin-2-one …
Investigational
Matched Iupac: … 5-methyl-2-(piperazin-1-yl)benzene-1-sulfonic acid …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Investigational
Matched Iupac: … 6-(piperidine-1-carbonyl)quinoxaline …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Investigational
CT-322 is a proprietary Adnectin(TM) protein therapeutic that, in preclinical studies, specifically binds to vascular endothelial growth factor receptor 2 (VEGFR-2), which regulates the primary tumor angiogenesis pathway. As a result, CT-322 blocks all known ligands for VEGFR-2.
Investigational
Investigational
Matched Iupac: … 3-[3-(tert-butylsulfanyl)-1-{[4-(6-ethoxypyridin-3-yl)phenyl]methyl}-5-[(5-methylpyridin-2-yl)methoxy …
Matched Salts cas: … 1196070-26-4
Tezampanel is an AMPA receptor antagonist.
Investigational
Matched Salts cas: … 317819-68-4
Matched Categories: … Heterocyclic Compounds, 1-Ring …
IPH-2101 (NN-1975), a fully human monoclonal antibody developed for patients with acute myeloid leukemia.
Investigational
Meplazumab is a humanized anti-CD147 antibody being investigated as an add-on therapy in patients with COVID-19 pneumonia.
Investigational
Investigational
Matched Iupac: … N-(2-amino-4-fluorophenyl)-4-{[(2E)-3-(pyridin-3-yl)prop-2-enamido]methyl}benzamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Investigational
B38-CAP is structured as a carboxypeptidase and derived from Paenibacillus sp. The molecule, an Angiotensin Converting Enzyme 2 (ACE2)-like enzyme, shares structural similarities to the mammalian ACE2. B38-CAP is an ACE2-like enzyme which decreases angiotensin II levels. It is being investigated for treating hypertension, myocardial fibrosis, and cardiac dysfunction.
Investigational
APD668 is a novel, highly potent and orally active glucose-dependent insulinotropic receptor (GDIR) agonist intended to more efficiently stimulate insulin release by beta cells in response to elevated blood glucose levels, and to also avoid hypoglycemia.
Investigational
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Investigational
CT-011 is a humanized monoclonal antibody directed against a B7 family-associated protein, in patients with advanced haematological malignancies. It is directed against human PD-1 (programmed cell death 1; PDCD1), with immunomodulating and antitumor activities.
Investigational
Matched Description: … It is directed against human PD-1 (programmed cell death 1; PDCD1), with immunomodulating and antitumor …
Has antiproliferative effects on HIV-1 and reduces HIV-1 replication.
Investigational
Matched Description: … Has antiproliferative effects on HIV-1 and reduces HIV-1 replication. …
Investigational
Investigational
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds with 4 or More Rings …
An amino acid analogue and antibiotic derived from the bacterium Streptomyces alanosinicus with antimetabolite and potential antineoplastic activities.
Investigational
BG-777 is an immunomodulator with proven efficacy against viral and bacterial infections in preclinical studies.
Investigational
Investigational
Investigational
Matched Iupac: … (1R,5S)-1-(3,4-dichlorophenyl)-3-azabicyclo[3.1.0]hexane …
Displaying drugs 12576 - 12600 of 12637 in total