Displaying drugs 12626 - 12650 of 13600 in total
Cimlanod
Cimlanod is under investigation in clinical trial NCT02819271 (A First-in-Human Study of the Safety of Single Continuous Intravenous (IV) Infusions of CXL-1427 for up to 48 Hours in Healthy Volunteers).
Investigational
Matched Iupac: … N-hydroxy-5-methylfuran-2-sulfonamide …
Litoxetine
Litoxetine is under investigation in clinical trial NCT03397771 (DBPC Trial to Evaluate the Safety, Tolerability and Efficacy of Oral Litoxetine in Subjects With Urinary Incontinence).
Investigational
Matched Iupac: … 4-[(naphthalen-2-yl)methoxy]piperidine …
Acetyldinaline
Acetyldinaline is under investigation in clinical trial NCT00005624 (CI-994 in Treating Patients With Advanced Myeloma).
Investigational
Matched Iupac: … 4-amino-N-(2-aminophenyl)benzamide …
DS-1211
DS-1211 is a potent and selective novel small molecule tissue-nonspecific alkaline phosphatase (TNAP) inhibitor.
Investigational
Matched Iupac: … (2R)-2-acetamido-4-methylpentanoic acid …
Tallimustine
Tallimustine, a benzoyl mustard derivative of distamycin A, is an alkylating agent that binds to the minor groove of DNA.[A182036,A182039] It's association with severe myelotoxicity lead to the end of its development in favour of α-halogenoacrylamide derivatives such as brostallicin, which have a favourable cytotoxicity/myelotoxicity ratio.[A182039,A182045] Newer generations of DNA...
Experimental
Matched Iupac: … 4-{4-[bis(2-chloroethyl)amino]benzamido}-N-[5-({5-[(2-carbamimidoylethyl)carbamoyl]-1-methyl-1H-pyrrol ... -3-yl}carbamoyl)-1-methyl-1H-pyrrol-3-yl]-1-methyl-1H-pyrrole-2-carboxamide …
Matched Salts cas: … 118438-45-2 …
Matched Salts cas: … 118438-45-2 …
Belotecan
Belotecan has been investigated for the treatment of Epithelial Ovarian Cancer.
Investigational
Matched Iupac: … (19S)-19-ethyl-19-hydroxy-10-{2-[(propan-2-yl)amino]ethyl}-17-oxa-3,13-diazapentacyclo[11.8.0.0^{2,11 ... }.0^{4,9}.0^{15,20}]henicosa-1(21),2(11),3,5,7,9,15(20)-heptaene-14,18-dione …
PF-5190457
PF-5190457 is under investigation in clinical trial NCT01522807 (A Study Of Three PF-05190457 Formulations In Healthy Volunteers).
Investigational
Matched Iupac: … 2-{2-methylimidazo[2,1-b][1,3]thiazol-6-yl}-1-{2-[(1R)-5-(6-methylpyrimidin-4-yl)-2,3-dihydro-1H-inden …
Lerociclib
Lerociclib is under investigation in clinical trial NCT02983071 (G1T38, a CDK 4/6 Inhibitor, in Combination With Fulvestrant in Hormone Receptor-positive, Her2-negative Locally Advanced or Metastatic Breast Cancer).
Investigational
Matched Iupac: … 12'-({5-[4-(propan-2-yl)piperazin-1-yl]pyridin-2-yl}amino)-2',5',11',13'-tetraazaspiro[cyclohexane-1,3 …
Matched Description: … Lerociclib is under investigation in clinical trial NCT02983071 (G1T38, a CDK 4/6 Inhibitor, in Combination …
Matched Description: … Lerociclib is under investigation in clinical trial NCT02983071 (G1T38, a CDK 4/6 Inhibitor, in Combination …
3-Allylfentanyl
3-allyfentanyl is a fentanyl derivative opioid that can cause itching, nausea and serious respiratory depression. Fentanyl and its analogs have killed thousands of people around the world as drugs of abuse.
Illicit
Matched Iupac: … N-phenyl-N-[(3S,4R)-1-(2-phenylethyl)-3-(prop-2-en-1-yl)piperidin-4-yl]propanamide …
Fallypride
Fallypride is under investigation in clinical trial NCT02310360 (Striatal and Extra-striatal Dopamine Release in Response to Food in Healthy Humans).
Investigational
Matched Iupac: … 5-(3-fluoropropyl)-2,3-dimethoxy-N-{[(2S)-1-(prop-2-en-1-yl)pyrrolidin-2-yl]methyl}benzamide …
Methopterin
Methopterin is thought to have effects on osteoclasts and to inhibit inflammatory bone destruction.
Investigational
Matched Iupac: … (2S)-2-[(4-{[(2-amino-4-oxo-3,4-dihydropteridin-6-yl)methyl](methyl)amino}phenyl)formamido]pentanedioic …
N-Carboxymethionine
Experimental
Matched Iupac: … (2S)-2-(carboxyamino)-4-(methylsulfanyl)butanoic acid …
3-(Benzoylamino)-L-Alanine
Experimental
Matched Iupac: … (2S)-2-amino-3-(phenylformamido)propanoic acid …
Iproniazid
Withdrawn from the Canadian market in July 1964 due to interactions with food products containing tyrosine.
Withdrawn
Matched Iupac: … N'-(propan-2-yl)pyridine-4-carbohydrazide …
Clomethiazole
Clomethiazole is a well-established γ-aminobutyric acid (GABAA)-mimetic drug. It is a sedative and hypnotic that is widely used in treating and preventing symptoms of acute alcohol withdrawal. It is a drug which is structurally related to thiamine (vitamin B1) but acts like a sedative, hypnotic, muscle relaxant and anticonvulsant. It...
Investigational
Matched Iupac: … 5-(2-chloroethyl)-4-methyl-1,3-thiazole …
Caramiphen
Caramiphen is a cholinergic antagonist used in Parkinson's disease. Additionally, it is used, in combination with phenylpropanolamine, as a cough suppressant and nasal decongestant for the symptomatic treatment of seasonal respiratory conditions.
Experimental
Vet approved
Matched Iupac: … 2-(diethylamino)ethyl 1-phenylcyclopentane-1-carboxylate …
Lesogaberan
Lesogaberan has been used in trials studying the treatment and basic science of GERD, Reflux, Heartburn, Regurgitation, and Reflux Disease, among others.
Investigational
Matched Iupac: … [(2R)-3-amino-2-fluoropropyl]phosphinic acid …
Tricaprylin
Tricaprilin has been used in trials studying the supportive care and treatment of Alzheimer's Disease.
Investigational
Matched Iupac: … 1,3-bis(octanoyloxy)propan-2-yl octanoate …
Displaying drugs 12626 - 12650 of 13600 in total