Displaying drugs 1251 - 1275 of 2129 in total
Nitrendipine
Nitrendipine is a calcium channel blocker with marked vasodilator action. It is an effective antihypertensive agent and differs from other calcium channel blockers in that it does not reduce glomerular filtration rate and is mildly natriuretic, rather than sodium retentive.
Approved
Investigational
Matched Synonyms: … 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid ethyl methyl ester …
Matched Iupac: … 3-ethyl 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate …
Matched Description: … It is an effective antihypertensive agent and differs from other calcium channel blockers in that it ... does not reduce glomerular filtration rate and is mildly natriuretic, rather than sodium retentive. …
Matched Categories: … ACE Inhibitors and Calcium Channel Blockers ... enalapril and nitrendipine ... Calcium-Regulating Hormones and Agents …
Matched Iupac: … 3-ethyl 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate …
Matched Description: … It is an effective antihypertensive agent and differs from other calcium channel blockers in that it ... does not reduce glomerular filtration rate and is mildly natriuretic, rather than sodium retentive. …
Matched Categories: … ACE Inhibitors and Calcium Channel Blockers ... enalapril and nitrendipine ... Calcium-Regulating Hormones and Agents …
Fludiazepam
Fludiazepam is a drug which is a benzodiazepine derivative. It possesses anxiolytic, anticonvulsant, sedative and skeletal muscle relaxant properties. It is a scheduled drug in the U.S., but is approved for use in Japan.
Experimental
Illicit
Matched Synonyms: … 7-chloro-5-(o-Fluorophenyl)-1,3-dihydro-1-methyl-2H-1,4-benzodiazepin-2-one …
Matched Iupac: … 7-chloro-5-(2-fluorophenyl)-1-methyl-2,3-dihydro-1H-1,4-benzodiazepin-2-one …
Matched Description: … It possesses anxiolytic, anticonvulsant, sedative and skeletal muscle relaxant properties. …
Matched Categories: … Benzodiazepines and benzodiazepine derivatives …
Matched Iupac: … 7-chloro-5-(2-fluorophenyl)-1-methyl-2,3-dihydro-1H-1,4-benzodiazepin-2-one …
Matched Description: … It possesses anxiolytic, anticonvulsant, sedative and skeletal muscle relaxant properties. …
Matched Categories: … Benzodiazepines and benzodiazepine derivatives …
CP-271485
Experimental
Matched Synonyms: … (6S)-4-Benzyl-6-(1-methyl-2,2-dioxido-1,3-dihydro-2,1-benzothiazol-5-yl)-3-morpholinone …
Matched Iupac: … 5-[(2S)-4-benzyl-5-oxomorpholin-2-yl]-1-methyl-1,3-dihydro-2lambda6,1-benzothiazole-2,2-dione …
Matched Iupac: … 5-[(2S)-4-benzyl-5-oxomorpholin-2-yl]-1-methyl-1,3-dihydro-2lambda6,1-benzothiazole-2,2-dione …
Trimethoprim
Trimethoprim is an antifolate antibacterial agent that inhibits bacterial dihydrofolate reductase (DHFR), a critical enzyme that catalyzes the formation of tetrahydrofolic acid (THF) - in doing so, it prevents the synthesis of bacterial DNA and ultimately continued bacterial survival. Trimethoprim is often used in combination with sulfamethoxazole due to their...
Approved
Vet approved
Matched Synonyms: … 5-[(3,4,5-trimethoxyphenyl)methyl]-2,4-pyrimidinediamine …
Matched Iupac: … 5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-diamine …
Matched Description: … of bacterial DNA and ultimately continued bacterial survival. ... L11893] Trimethoprim is often used in combination with [sulfamethoxazole] due to their complementary and ... synergistic mechanisms but may be used as a monotherapy in the treatment and/or prophylaxis of urinary …
Matched Mixtures name: … Sulfamethoxazole and Trimethoprim ... Sulfamethoxazole and Trimethoprim ... Sulfamethoxazole and Trimethoprim …
Matched Categories: … Trimethoprim and Derivatives ... Sulfonamides and trimethoprim ... sulfamoxole and trimethoprim ... sulfametrole and trimethoprim ... sulfadiazine and trimethoprim …
Matched Iupac: … 5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-diamine …
Matched Description: … of bacterial DNA and ultimately continued bacterial survival. ... L11893] Trimethoprim is often used in combination with [sulfamethoxazole] due to their complementary and ... synergistic mechanisms but may be used as a monotherapy in the treatment and/or prophylaxis of urinary …
Matched Mixtures name: … Sulfamethoxazole and Trimethoprim ... Sulfamethoxazole and Trimethoprim ... Sulfamethoxazole and Trimethoprim …
Matched Categories: … Trimethoprim and Derivatives ... Sulfonamides and trimethoprim ... sulfamoxole and trimethoprim ... sulfametrole and trimethoprim ... sulfadiazine and trimethoprim …
Denatonium
Experimental
Investigational
Matched Synonyms: … Benzyldiethyl((2,6-xylylcarbamoyl)methyl)ammonium …
Matched Iupac: … benzyl({[(2,6-dimethylphenyl)carbamoyl]methyl})diethylazanium …
Matched Iupac: … benzyl({[(2,6-dimethylphenyl)carbamoyl]methyl})diethylazanium …
MMDA
MMDA, or 3-methoxy-4,5-methylenedioxyamphetamine, is a member of the amphetamine drug class with stimulant and psychedelic properties. It also acts as an entheogen and an entactogen. MMDA bears resemblance to the psychopharmacologically active essential oils elemicin and myristicin found in nutmeg. The effects of MMDA includes feelings of euphoria and warmth,...
Experimental
Illicit
Matched Synonyms: … 3-Methoxy-alpha-methyl-4,5-methylenedioxyphenethylamine …
Matched Description: … MMDA bears resemblance to the psychopharmacologically active essential oils elemicin and myristicin found ... It also acts as an entheogen and an entactogen. ... or 3-methoxy-4,5-methylenedioxyamphetamine, is a member of the amphetamine drug class with stimulant and …
Matched Categories: … Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates …
Matched Description: … MMDA bears resemblance to the psychopharmacologically active essential oils elemicin and myristicin found ... It also acts as an entheogen and an entactogen. ... or 3-methoxy-4,5-methylenedioxyamphetamine, is a member of the amphetamine drug class with stimulant and …
Matched Categories: … Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates …
Tibolone
Tibolone is a synthetic steroid hormone drug, which is mainly non-selective in its binding profile, acting as an agonist primarily at estrogen receptors (ER), with a preference for ER alpha .
Tibolone (Livial, Org OD 14), produced by Organon (West Orange, NJ), is a synthetic steroid that possesses estrogenic, androgenic...
Approved
Investigational
Matched Synonyms: … 17-hydroxy-7alpha-methyl-19-nor-17alpha-pregn-5(10)-en-20-yn-3-one …
Matched Description: … estrogenic, androgenic and progestogenic properties. ... Tibolone is approved in 90 countries to manage menopausal symptoms and in 45 countries to prevent the ... been used in Europe for almost 2 decades, primarily for the prevention of postmenopausal osteoporosis and …
Matched Categories: … Genito Urinary System and Sex Hormones ... Estrogens, Antiestrogens, and Estrogen Agonist-Antagonists ... Sex Hormones and Modulators of the Genital System ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Description: … estrogenic, androgenic and progestogenic properties. ... Tibolone is approved in 90 countries to manage menopausal symptoms and in 45 countries to prevent the ... been used in Europe for almost 2 decades, primarily for the prevention of postmenopausal osteoporosis and …
Matched Categories: … Genito Urinary System and Sex Hormones ... Estrogens, Antiestrogens, and Estrogen Agonist-Antagonists ... Sex Hormones and Modulators of the Genital System ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Etizolam
Etizolam is a thienodiazepine which is chemically related to benzodiazepine (BDZ) drug class; it differs from BDZs in having a benzene ring replaced with a thiophene ring. It is an agonist at GABA-A receptors and possesses amnesic, anxiolytic, anticonvulsant, hypnotic, sedative and skeletal muscle relaxant properties. Initially introduced in 1983...
Experimental
Matched Synonyms: … 4-(o-Chlorophenyl)-2-ethyl-9-methyl-6H-thieno(3,2-f)-s-triazolo(4,3-a)(1,4)diazepine …
Matched Iupac: … 7-(2-chlorophenyl)-4-ethyl-13-methyl-3-thia-1,8,11,12-tetraazatricyclo[8.3.0.0^{2,6}]trideca-2(6),4,7,10,12 …
Matched Description: … and skeletal muscle relaxant properties. ... disorders, etizolam is marketed in Japan, Italy and India. ... It is an agonist at GABA-A receptors and possesses amnesic, anxiolytic, anticonvulsant, hypnotic, sedative …
Matched Categories: … Benzodiazepine hypnotics and sedatives ... Hypnotics and Sedatives ... Benzodiazepines and benzodiazepine derivatives …
Matched Iupac: … 7-(2-chlorophenyl)-4-ethyl-13-methyl-3-thia-1,8,11,12-tetraazatricyclo[8.3.0.0^{2,6}]trideca-2(6),4,7,10,12 …
Matched Description: … and skeletal muscle relaxant properties. ... disorders, etizolam is marketed in Japan, Italy and India. ... It is an agonist at GABA-A receptors and possesses amnesic, anxiolytic, anticonvulsant, hypnotic, sedative …
Matched Categories: … Benzodiazepine hypnotics and sedatives ... Hypnotics and Sedatives ... Benzodiazepines and benzodiazepine derivatives …
AMG-900
Investigational
Matched Synonyms: … 1-phthalazinamine, n-(4-((3-(2-amino-4-pyrimidinyl)-2-pyridinyl)oxy)phenyl)-4-(4-methyl-2-thienyl)- …
Nedometinib
Investigational
Matched Synonyms: … 2-((2-fluoro-4-iodophenyl)amino)-n-(2-hydroxyethoxy)-1-methyl-1h-pyrrolo(2,3-b)pyridine-3-carboxamide …
Matched Iupac: … 2-[(2-fluoro-4-iodophenyl)amino]-N-(2-hydroxyethoxy)-1-methyl-1H-pyrrolo[2,3-b]pyridine-3-carboxamide …
Matched Iupac: … 2-[(2-fluoro-4-iodophenyl)amino]-N-(2-hydroxyethoxy)-1-methyl-1H-pyrrolo[2,3-b]pyridine-3-carboxamide …
Sevasemten
Sevasemten is under investigation in clinical trial NCT05291091 (Phase 2 Study of EDG-5506 in Becker Muscular Dystrophy (GRAND CANYON)).
Investigational
Matched Synonyms: … 2-[(5-fluoropyridin-3-yl)methyl]-6-[2-(2,2,2- trifluoroethoxy)pyrimidin-5-yl]pyridazin-3(2H)-one …
AZD2066
Investigational
Matched Synonyms: … Pyridine, 4-(5-((1r)-1-(5-(3-chlorophenyl)-3-isoxazolyl)ethoxy)-4-methyl-4h-1,2,4-triazol-3-yl)- …
Matched Iupac: … 4-{5-[(1R)-1-[5-(3-chlorophenyl)-1,2-oxazol-3-yl]ethoxy]-4-methyl-4H-1,2,4-triazol-3-yl}pyridine …
Matched Iupac: … 4-{5-[(1R)-1-[5-(3-chlorophenyl)-1,2-oxazol-3-yl]ethoxy]-4-methyl-4H-1,2,4-triazol-3-yl}pyridine …
FDL169
Investigational
Matched Synonyms: … 2-(7-ethoxy-4-(3-fluorophenyl)-1-oxophthalazin-2(1H)-yl)-N-methyl-N-(2-methylbenzo(D)oxazol-6-yl)acetamide ... 2-(7-ethoxy-4-(3-fluorophenyl)-1-oxophthalazin-2(1H)-yl)-N-methyl-N-(2-methylbenzo[D]oxazol-6-yl)acetamide …
Matched Iupac: … 2-[7-ethoxy-4-(3-fluorophenyl)-1-oxo-1,2-dihydrophthalazin-2-yl]-N-methyl-N-(2-methyl-1,3-benzoxazol- …
Matched Iupac: … 2-[7-ethoxy-4-(3-fluorophenyl)-1-oxo-1,2-dihydrophthalazin-2-yl]-N-methyl-N-(2-methyl-1,3-benzoxazol- …
BTZ-043
Investigational
Matched Synonyms: … 2-((2s)-2-methyl-1,4-dioxa-8-azaspiro(4.5)decan-8-yl)-8-nitro-6-trifluoromethyl-4h-1,3-benzothiazin-4 ... 4h-1,3-benzothiazin-4-one, 2-((2s)-2-methyl-1,4-dioxa-8-azaspiro(4.5)dec-8-yl)-8-nitro-6-(trifluoromethyl …
Matched Iupac: … 2-[(2S)-2-methyl-1,4-dioxa-8-azaspiro[4.5]decan-8-yl]-8-nitro-6-(trifluoromethyl)-4H-1,3-benzothiazin …
Matched Iupac: … 2-[(2S)-2-methyl-1,4-dioxa-8-azaspiro[4.5]decan-8-yl]-8-nitro-6-(trifluoromethyl)-4H-1,3-benzothiazin …
Promethazine
Promethazine, originally known as 3,277 R.P., is an N-dimethylaminopropyl derivative of phenothiazine that was developed in France in 1946. Promethazine antagonizes a variety of receptors, allowing it to be used for a number of indications including allergic reactions, pain, sedation, nausea, and vomiting.[A189907,A190153,A190159,A190150,A190171]
Promethazine was granted FDA approval before 29...
Approved
Investigational
Matched Synonyms: … (2-dimethylamino-2-methyl)ethyl-N-dibenzoparathiazine ... N-(2'-dimethylamino-2'-methyl)ethylphenothiazine …
Matched Description: … allowing it to be used for a number of indications including allergic reactions, pain, sedation, nausea, and …
Matched Mixtures name: … Meperidine Hcl and Promethazine Hcl ... Promethazine Hydrochloride and Codeine Phosphate ... Promethazine HCl and Codeine Phosphate …
Matched Categories: … prednisolone and promethazine ... Miscellaneous Anxiolytics Sedatives and Hypnotics …
Matched Description: … allowing it to be used for a number of indications including allergic reactions, pain, sedation, nausea, and …
Matched Mixtures name: … Meperidine Hcl and Promethazine Hcl ... Promethazine Hydrochloride and Codeine Phosphate ... Promethazine HCl and Codeine Phosphate …
Matched Categories: … prednisolone and promethazine ... Miscellaneous Anxiolytics Sedatives and Hypnotics …
Fluoxymesterone
An anabolic steroid that has been used in the treatment of male hypogonadism, delayed puberty in males, and in the treatment of breast neoplasms in women.
Approved
Illicit
Matched Synonyms: … 17α-Methyl-9α-fluoro-11β-hydroxytesterone ... 11β,17β-Dihydroxy-9α-fluoro-17α-methyl-4-androster-3-one …
Matched Description: … anabolic steroid that has been used in the treatment of male hypogonadism, delayed puberty in males, and …
Matched Categories: … Genito Urinary System and Sex Hormones ... Sex Hormones and Modulators of the Genital System ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Description: … anabolic steroid that has been used in the treatment of male hypogonadism, delayed puberty in males, and …
Matched Categories: … Genito Urinary System and Sex Hormones ... Sex Hormones and Modulators of the Genital System ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Losartan
Losartan is an angiotensin II receptor blocker (ARB) used to treat hypertension. Angiotensin-converting enzyme (ACE) inhibitors are used for a similar indication but are associated with a cough. When patients with ACE inhibitor associated coughs are switched to ARBs like losartan, they have an incidence of cough similar to placebo...
Approved
Matched Synonyms: … (2-butyl-4-chloro-1-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1H-imidazol-5-yl)methanol ... 2-n-butyl-4-chloro-5-hydroxymethyl-1-[(2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl]imidazole …
Matched Iupac: … (2-butyl-4-chloro-1-{[2'-(2H-1,2,3,4-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl]methyl}-1H-imidazol-5-yl)methanol …
Matched Description: … available as losartan potassium oral tablets as well as a combination tablet of losartan potassium and ... [L7423,L7426] Patients taking losartan should have their renal function and potassium levels monitored …
Matched Mixtures name: … Losartan Potassium and Hydrochlorothiazide ... Losartan Potassium and Hydrochlorothiazide ... Losartan Potassium and Hydrochlorothiazide …
Matched Categories: … losartan and diuretics ... losartan and amlodipine ... Angiotensin II receptor blockers (ARBs) and diuretics ... Angiotensin II receptor blockers (ARBs) and calcium channel blockers …
Matched Iupac: … (2-butyl-4-chloro-1-{[2'-(2H-1,2,3,4-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl]methyl}-1H-imidazol-5-yl)methanol …
Matched Description: … available as losartan potassium oral tablets as well as a combination tablet of losartan potassium and ... [L7423,L7426] Patients taking losartan should have their renal function and potassium levels monitored …
Matched Mixtures name: … Losartan Potassium and Hydrochlorothiazide ... Losartan Potassium and Hydrochlorothiazide ... Losartan Potassium and Hydrochlorothiazide …
Matched Categories: … losartan and diuretics ... losartan and amlodipine ... Angiotensin II receptor blockers (ARBs) and diuretics ... Angiotensin II receptor blockers (ARBs) and calcium channel blockers …
3-({1-[3-CARBAMIMIDOYL-1-(4-CARBAMIMIDOYL-BENZYLCARBAMOYL)-PROPYLCARBAMOYL]-2-METHYL-BUTYLSULFAMOYL}-METHYL)-BENZOIC ACID
Experimental
Matched Name: … METHYL)-BENZOIC ACID ... 3-({1-[3-CARBAMIMIDOYL-1-(4-CARBAMIMIDOYL-BENZYLCARBAMOYL)-PROPYLCARBAMOYL]-2-METHYL-BUTYLSULFAMOYL}- …
Matched Iupac: … -methylbutyl]sulfamoyl}methyl)benzoic acid ... 3-({[(1R,2R)-1-{[(1S)-3-carbamimidoyl-1-{[(4-carbamimidoylphenyl)methyl]carbamoyl}propyl]carbamoyl}-2 …
Matched Iupac: … -methylbutyl]sulfamoyl}methyl)benzoic acid ... 3-({[(1R,2R)-1-{[(1S)-3-carbamimidoyl-1-{[(4-carbamimidoylphenyl)methyl]carbamoyl}propyl]carbamoyl}-2 …
17alpha-methyl-3beta,17beta-dihydroxyandrost-4-ene
Experimental
Illicit
Matched Name: … 17alpha-methyl-3beta,17beta-dihydroxyandrost-4-ene …
17Alpha-methyl-3beta,17beta-dihydroxy-5alpha-androstane
Experimental
Illicit
Matched Name: … 17Alpha-methyl-3beta,17beta-dihydroxy-5alpha-androstane …
2-amino-8-methyl-4(1H)-quinazolinone
Experimental
Matched Name: … 2-amino-8-methyl-4(1H)-quinazolinone …
Matched Iupac: … 2-amino-8-methyl-1,4-dihydroquinazolin-4-one …
Matched Iupac: … 2-amino-8-methyl-1,4-dihydroquinazolin-4-one …
4-(Aminosulfonyl)-N-[(3,4,5-Trifluorophenyl)Methyl]-Benzamide
Experimental
Matched Name: … 4-(Aminosulfonyl)-N-[(3,4,5-Trifluorophenyl)Methyl]-Benzamide …
Matched Iupac: … 4-sulfamoyl-N-[(3,4,5-trifluorophenyl)methyl]benzamide …
Matched Iupac: … 4-sulfamoyl-N-[(3,4,5-trifluorophenyl)methyl]benzamide …
4-(Aminosulfonyl)-N-[(2,3,4-Trifluorophenyl)Methyl]-Benzamide
Experimental
Matched Name: … 4-(Aminosulfonyl)-N-[(2,3,4-Trifluorophenyl)Methyl]-Benzamide …
Matched Iupac: … 4-sulfamoyl-N-[(2,3,4-trifluorophenyl)methyl]benzamide …
Matched Iupac: … 4-sulfamoyl-N-[(2,3,4-trifluorophenyl)methyl]benzamide …
DERIVATIVE OF AKLANONIC ACID METHYL ESTER (AAME)
Experimental
Matched Name: … DERIVATIVE OF AKLANONIC ACID METHYL ESTER (AAME) …
Matched Iupac: … methyl 2-{3-[(1R,3S)-1,3-dihydroxypentyl]-4,5-dihydroxy-9,10-dioxo-9,10-dihydroanthracen-2-yl}acetate …
Matched Iupac: … methyl 2-{3-[(1R,3S)-1,3-dihydroxypentyl]-4,5-dihydroxy-9,10-dioxo-9,10-dihydroanthracen-2-yl}acetate …
Displaying drugs 1251 - 1275 of 2129 in total