Displaying drugs 13301 - 13325 of 13450 in total
TMC-647055
TMC647055 has been used in trials studying the treatment of Hepatitis C, Chronic Hepatitis C, Hepatitis C, Chronic, and Chronic Hepatitis C Virus.
Investigational
Matched Iupac: … cyclohexyl-22-methoxy-10,16-dimethyl-13-oxa-9lambda6-thia-1,8,10,16-tetraazapentacyclo[16.8.1.1^{2,6}.1^ …
Obicetrapib
Obicetrapib is under investigation in clinical trial NCT02241772 (A Study on the Effects of TA-8995 on Lp(a) in Subjects With Elevated Lp(a)).
Investigational
Matched Iupac: … 4-{[2-({[3,5-bis(trifluoromethyl)phenyl]methyl}[(2R,4S)-1-(ethoxycarbonyl)-2-ethyl-6-(trifluoromethyl …
Matched Description: … Lp(a) in Subjects With Elevated Lp(a)). ... Obicetrapib is under investigation in clinical trial NCT02241772 (A Study on the Effects of TA-8995 on …
Matched Description: … Lp(a) in Subjects With Elevated Lp(a)). ... Obicetrapib is under investigation in clinical trial NCT02241772 (A Study on the Effects of TA-8995 on …
Gepotidacin
Gepotidacin has been used in trials studying the treatment of Gonorrhea, Infections, Bacterial, and Infections, Respiratory Tract.
Investigational
Matched Iupac: … (3R)-3-({4-[({2H,3H,4H-pyrano[2,3-c]pyridin-6-yl}methyl)amino]piperidin-1-yl}methyl)-1,4,7-triazatricyclo …
Matched Salts cas: … 1624306-20-2 …
Matched Salts cas: … 1624306-20-2 …
Ifebemtinib
Investigational
Matched Iupac: … -({4-[(2-methyl-3-oxo-2,3-dihydro-1H-isoindol-4-yl)oxy]-5-(trifluoromethyl)pyrimidin-2-yl}amino)-N-(1- …
Dopastatin
Dopastatin is under investigation in clinical trial NCT04335357 (TBR-760 in Adult Patients With Non-functioning Pituitary Adenomas).
Investigational
Matched Iupac: … (2R)-N-[(4R,7S,10S,13R,16S,19R)-10-(4-aminobutyl)-4-{[(1S,2R)-1-carbamoyl-2-hydroxypropyl]carbamoyl}- ... pentaazacycloicosan-19-yl]-2,6-bis[2-({[(2R,4R,7R)-6-propyl-6,11-diazatetracyclo[7.6.1.0^{2,7}.0^{12,16}]hexadeca-1( …
INHIBITOR Q8467 OF DUPONT MERCK
Experimental
Matched Iupac: … 3-{[(4R,5S,6S,7R)-4,7-dibenzyl-3-(cyclopropylmethyl)-5,6-dihydroxy-2-oxo-1,3-diazepan-1-yl]methyl}-N- …
Mevastatin
Mevastatin or compactin is a cholesterol-lowering agent isolated from Penicillium citinium. It was the first discovered agent belonging to the class of cholesterol-lowering medications known as statins. During a search for antibiotic compounds produced by fungi in 1971, Akira Endo at Sankyo Co. (Japan) discovered a class of compounds that...
Experimental
Matched Iupac: … ,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl}-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1- …
Matched Description: … Mevastatin is a competitive inhibitor of HMG-Coenzyme A (HMG-CoA) reductase with a binding affinity 10,000 ... Mevastatin or compactin is a cholesterol-lowering agent isolated from Penicillium citinium. ... (Japan) discovered a class of compounds that appeared to lower plasma cholesterol levels. …
Matched Description: … Mevastatin is a competitive inhibitor of HMG-Coenzyme A (HMG-CoA) reductase with a binding affinity 10,000 ... Mevastatin or compactin is a cholesterol-lowering agent isolated from Penicillium citinium. ... (Japan) discovered a class of compounds that appeared to lower plasma cholesterol levels. …
Tetrahydrogestrinone
Experimental
Matched Iupac: … (1S,3aS,3bS,11aS)-1,11a-diethyl-1-hydroxy-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,11aH-cyclopenta[a]phenanthren …
LY-3200882
LY-3200882 is under investigation in clinical trial NCT04158700 (A Study of LY3200882 and Pembrolizumab in Participants With Advanced Cancer).
Investigational
Matched Iupac: … 2-{4-[(4-{[1-cyclopropyl-3-(oxan-4-yl)-1H-pyrazol-4-yl]oxy}pyridin-2-yl)amino]pyridin-2-yl}propan-2-ol …
Matched Description: … LY-3200882 is under investigation in clinical trial NCT04158700 (A Study of LY3200882 and Pembrolizumab …
Matched Description: … LY-3200882 is under investigation in clinical trial NCT04158700 (A Study of LY3200882 and Pembrolizumab …
Nitrocefin
Nitrocefin is a chromogenic cephalosporin substrate used to detect the presence of beta-lactamase enzymes, an important mediator of bacterial antibiotic resistance. While other detection methods exist, such as PCR, nitrocefin allows for rapid detection using few materials and inexpensive equipment.
Experimental
Matched Iupac: … (6R,7R)-3-[(E)-2-(2,4-dinitrophenyl)ethenyl]-8-oxo-7-[2-(thiophen-2-yl)acetamido]-5-thia-1-azabicyclo …
Matched Description: … Nitrocefin is a chromogenic cephalosporin substrate used to detect the presence of beta-lactamase enzymes …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Description: … Nitrocefin is a chromogenic cephalosporin substrate used to detect the presence of beta-lactamase enzymes …
Matched Categories: … Compounds used in a research, industrial, or household setting …
MK-8666
MK-8666 is under investigation in clinical trial NCT01971554 (Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of MK-8666 in Participants With Type 2 Diabetes Mellitus (MK-8666-003)).
Investigational
Matched Iupac: … methanesulfonylpropoxy)-2',6'-dimethyl-[1,1'-biphenyl]-3-yl]methoxy}-9-azatricyclo[4.4.0.0^{2,4}]deca-1( …
Trypanothione
Experimental
Matched Iupac: … (2S)-2-amino-4-{[(1R)-1-{[({3-[(4-{2-[(2R)-2-[(4S)-4-amino-4-carboxybutanamido]-3-sulfanylpropanamido …
4-(Cytidine 5'-diphospho)-2-C-methyl-D-erythritol
Experimental
Matched Iupac: … {[(2R,3S,4R,5R)-3,4-dihydroxy-5-(2-hydroxy-4-imino-1,4-dihydropyrimidin-1-yl)oxolan-2-yl]methoxy}({hydroxy …
TETRAHEDRAL INTERMEDIATE OF BLASTICIDIN S
Experimental
Matched Iupac: … (2S,3S,6R)-6-[(4S)-4-amino-4-hydroxy-2-oxo-1,2,3,4-tetrahydropyrimidin-1-yl]-3-[(3S)-3-amino-5-(N-methylcarbamimidamido …
Sulfatide
Any of a class of cerebroside sulfuric esters, they are found largely in the medullated nerve fibers and may accumulate in metachromatic leukodystrophy.
Experimental
Matched Iupac: … 2R,3R,4S,5S,6R)-3,5-dihydroxy-2-{[(2S,3R,4E)-3-hydroxy-2-[(2R)-2-hydroxytetracosanamido]octadec-4-en-1- …
Matched Description: … Any of a class of cerebroside sulfuric esters, they are found largely in the medullated nerve fibers …
Matched Description: … Any of a class of cerebroside sulfuric esters, they are found largely in the medullated nerve fibers …
Pefcalcitol
Pefcalcitol has been investigated for the basic science of Psoriasis.
Investigational
Matched Iupac: … 2-[(1S)-1-[(3aS,7E,7aS)-7-{2-[(1Z,3S,5R)-3,5-dihydroxy-2-methylidenecyclohexylidene]ethylidene}-3a-methyl …
Volasertib
Volasertib has been used in trials studying the treatment of Leukemia, Neoplasms, Leukemia, Myeloid, Acute, Myelodysplastic Syndromes, and Leukemia, Monocytic, Acute, among others.
Investigational
Matched Iupac: … 2-yl)-5,6,7,8-tetrahydropteridin-2-yl]amino}-3-methoxy-N-[(1r,4r)-4-[4-(cyclopropylmethyl)piperazin-1- …
Cefcapene
Experimental
Matched Iupac: … (6R,7R)-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)pent-2-enamido]-3-[(carbamoyloxy)methyl]-8-oxo-5-thia-1-azabicyclo …
Geldanamycin
Experimental
Investigational
Matched Iupac: … 16R)-13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1( …
Velusetrag
Velusetrag has been used in trials studying the treatment of Gastroparesis and Alzheimer's Disease. It is a highly selective serotonin receptor agonist effective in patients with chronic constipation. It is being developed by Theravance. Velusetrag was discovered by Theravance through the application of its multivalent drug design in a research...
Investigational
Matched Iupac: … 3R,5S)-8-[(2R)-2-hydroxy-3-(N-methylmethanesulfonamido)propyl]-8-azabicyclo[3.2.1]octan-3-yl]-2-oxo-1- …
Matched Description: … It is a highly selective serotonin receptor agonist effective in patients with chronic constipation. ... Velusetrag was discovered by Theravance through the application of its multivalent drug design in a research …
Matched Description: … It is a highly selective serotonin receptor agonist effective in patients with chronic constipation. ... Velusetrag was discovered by Theravance through the application of its multivalent drug design in a research …
BMS-986142
BMS-986142 is under investigation in clinical trial NCT02880670 (Pharmacokinetics and Metabolism Study of Radiolabeled BMS-986142 in Healthy Male Subjects).
Investigational
Matched Iupac: … (2S)-6-fluoro-5-[3-(8-fluoro-1-methyl-2,4-dioxo-1,2,3,4-tetrahydroquinazolin-3-yl)-2-methylphenyl]-2- …
Fostroxacitabine bralpamide
Investigational
Matched Iupac: … (2S)-pentan-2-yl (2S)-2-{[(S)-{[(2S,4S)-4-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-1,3-dioxolan-2-yl …
Vinblastine N-oxide
Investigational
Matched Iupac: … ium-1-olate ... 13-(methoxycarbonyl)-1,11-diazatetracyclo[13.3.1.0^{4,12}.0^{5,10}]nonadeca-4(12),5(10),6,8-tetraen-1- …
Displaying drugs 13301 - 13325 of 13450 in total