Displaying drugs 13626 - 13650 of 13829 in total
9-amino-n-[3-(dimethylamino)propyl]acridine-4-carboxamide
9-amino-n-[3-(dimethylamino)propyl]acridine-4-carboxamide is an inactive derivative of the antitumour agents N-[2-(dimethylamino)ethyl]acridine-4-carboxamide (DACA) and 9-amino-DACA.
Experimental
Matched Description: … agents N-[2-(dimethylamino)ethyl]acridine-4-carboxamide (DACA) and 9-amino-DACA. ... 9-amino-n-[3-(dimethylamino)propyl]acridine-4-carboxamide is an inactive derivative of the antitumour …
Quisqualic acid
Quisqualic acid is an agonist at two subsets of excitatory amino acid receptors, ionotropic receptors that directly control membrane channels and metabotropic receptors that indirectly mediate calcium mobilization from intracellular stores. The compound is obtained from the seeds and fruit of Quisqualis chinensis.
Experimental
Matched Iupac: … (2S)-2-amino-3-(3,5-dioxo-1,2,4-oxadiazolidin-2-yl)propanoic acid …
Matched Description: … The compound is obtained from the seeds and fruit of _Quisqualis chinensis_. ... Quisqualic acid is an agonist at two subsets of excitatory amino acid receptors, ionotropic receptors …
Matched Description: … The compound is obtained from the seeds and fruit of _Quisqualis chinensis_. ... Quisqualic acid is an agonist at two subsets of excitatory amino acid receptors, ionotropic receptors …
Cyclopropane
Cyclopropane was initially investigated because it was thought to be the toxic element in ethylene. Instead, it turned out to be an excellent anesthetic with very rapid onset and recovery while maintaining stable hemodynamics. Its use was ultimately limited because it was highly explosive.
Experimental
Matched Description: … Cyclopropane was initially investigated because it was thought to be the toxic element in ethylene. …
BN‐Brachyury vaccine
BN‐Brachyury vaccine is a novel prime‐boost therapeutic cancer immunotherapy. It is composed of the MVA-BN-brachyury-TRICOM vaccine and the fowlpox virus(FPV)‐Brachyury booster vaccine.
Investigational
Matched Description: … It is composed of the [MVA-BN-brachyury-TRICOM vaccine] and the fowlpox virus(FPV)‐Brachyury booster …
Eftansomatropin alfa
Eftansomatropin alfa (GX-H9) comprises a recombinant human growth hormone fused to hyFc, a synthetic hybrid Fc fragment. It is under investigation for the treatment of growth hormone deficiency.
Investigational
Matched Description: … [L48275] It is under investigation for the treatment of growth hormone deficiency. …
Estrane-3,17-dione
Estrane-3,17-dione is a potent inhibitor of isomerase.
Experimental
Matched Description: … Estrane-3,17-dione is a potent inhibitor of isomerase. …
MK-886
MK-886 is an experimental inhibitor of leukotriene synthesis.
Experimental
Matched Iupac: … 3-[3-(tert-butylsulfanyl)-1-[(4-chlorophenyl)methyl]-5-(propan-2-yl)-1H-indol-2-yl]-2,2-dimethylpropanoic …
Matched Description: … MK-886 is an experimental inhibitor of leukotriene synthesis. …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Description: … MK-886 is an experimental inhibitor of leukotriene synthesis. …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Tabituximab barzuxetan yttrium Y-90
A version of tabituximab barzuxetan radiolabeled with yttrium-90.
Investigational
Matched Description: … A version of [tabituximab barzuxetan] radiolabeled with yttrium-90. …
Tropatepine
Tropatepine has been used in France for its antiparkinsons activities .
Experimental
Matched Iupac: … (1R,5S)-8-methyl-3-{9-thiatricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3(8),4,6,11,13-hexaen-2-ylidene}-8-azabicyclo …
Matched Description: … Tropatepine has been used in France for its antiparkinsons activities [A175024]. …
Matched Description: … Tropatepine has been used in France for its antiparkinsons activities [A175024]. …
Pyrroloquinoline Quinone
A pyrrolo-quinoline having two adjacent keto-groups at the 4 and 5 positions and three acidic carboxyl groups. It is a coenzyme of some DEHYDROGENASES. [PubChem]
Experimental
Matched Description: … It is a coenzyme of some DEHYDROGENASES. [PubChem] …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Etaracizumab
Etaracizumab has been investigated for the treatment of Psoriasis, Renal Cell Carcinoma, Stage IV Renal Cell Cancer, Recurrent Renal Cell Cancer, and Stage III Renal Cell Cancer.
Investigational
Matched Description: … Etaracizumab has been investigated for the treatment of Psoriasis, Renal Cell Carcinoma, Stage IV Renal …
PAS-004
PAS-004 is an allosteric MEK 1/2 inhibitor being developed by Pasithea Therapeutics. It is being investigated for the treatment of neurofibromatosis 1 and Noonan syndrome.
Investigational
Matched Description: … PAS-004 is an allosteric MEK 1/2 inhibitor being developed by Pasithea Therapeutics. ... It is being investigated for the treatment of neurofibromatosis 1 and Noonan syndrome. …
Matrix-M
Matrix-M is a saponin-based adjuvant made of nanometer particles, cholesterol, and phospholipid that is developed by Novavax. This compound is administered alongside vaccines to enhance biological functions: creating robust and long-lasting immune responses that may allow for dose-sparing of vaccines.
Investigational
Matched Description: … Matrix-M is a saponin-based adjuvant made of nanometer particles, cholesterol, and phospholipid that ... biological functions: creating robust and long-lasting immune responses that may allow for dose-sparing of …
Acetic acid C-11
Acetic acid C-11 is under investigation in clinical trial NCT01953965 (Look at Way the Heart Functions in People With Pulmonary Hypertension (PH) Who Have Near Normal Right Ventricle (RV) Function and People With Pulmonary Hypertension Who Have Impaired RV Function. Using Imaging Studies PET Scan and Cardiac MRI.).
Investigational
Matched Description: … Acetic acid C-11 is under investigation in clinical trial NCT01953965 (Look at Way the Heart Functions ... in People With Pulmonary Hypertension (PH) Who Have Near Normal Right Ventricle (RV) Function and People …
(S)-Fluoxetine
An N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine that has S configuration (the antidepressant drug fluoxetine is a racemate comprising equimolar amounts of (R)- and (S)-fluoxetine).
Experimental
Matched Description: … has S configuration (the antidepressant drug fluoxetine is a racemate comprising equimolar amounts of …
FB-101
FB-101 is a c-Abl inhibitor. Developed by 1st Biotherapeutics, it is being investigated for the treatment of neurological disorders, such as Parkinson's Disease and amyotrophic lateral sclerosis (ALS).
Experimental
Investigational
Matched Description: … Developed by 1st Biotherapeutics, it is being investigated for the treatment of neurological disorders …
AMG-553
AMG-553 is an adoptive, anti-FLT3 chimeric antigen receptor T-cell therapy generated through transduction of autologous T-cells with a self-inactivating human immunodeficiency virus-1 based lentiviral vector.
Investigational
Matched Description: … 553 is an adoptive, anti-FLT3 chimeric antigen receptor T-cell therapy generated through transduction of …
MaxAdFVIII
MaxAdFVIII is an adenoviral vector that expresses the full-length human Factor VIII (hFVIII) cDNA. First developed by GenStar, it is being investigated for the treatment of hemophilia.
Investigational
Matched Description: … First developed by GenStar, it is being investigated for the treatment of hemophilia. …
Bacteroides thetaiotaomicron
Bacteroides thetaiotaomicron is a live biotherapeutic. Developed by 4D Pharma, Thetanix, an oral formulation comprising lyophilized Bacteroides thetaiotaomicron, is being investigated for the treatment of Crohn’s disease.
Investigational
Matched Description: … formulation comprising lyophilized Bacteroides thetaiotaomicron, is being investigated for the treatment of …
Ispectamab debotansine
Ispectamab debotansine is an antibody drug conjugate comprised of an anti-B cell maturation (BCMA) IgG1 humanized antibody conjugated covalently to the dibenzocyclooctyne (DBCO) noncleavable linker maytansinoid warhead.
Investigational
Matched Description: … Ispectamab debotansine is an antibody drug conjugate comprised of an anti-B cell maturation (BCMA) IgG1 …
Bapineuzumab
Bapineuzumab has been investigated for the treatment of Alzheimer's Disease.
Investigational
Matched Description: … Bapineuzumab has been investigated for the treatment of Alzheimer's Disease. …
Bi104
Bi104 is being investigated for the treatment of Angelman syndrome.
Investigational
Matched Description: … Bi104 is being investigated for the treatment of Angelman syndrome. …
Carisbamate
Carisbamate has been investigated in Alcohol Abuse, Substance Abuse, and Alcohol Dependence.
Investigational
Matched Iupac: … (2S)-2-(2-chlorophenyl)-2-hydroxyethyl carbamate …
Matched Description: … Carisbamate has been investigated in Alcohol Abuse, Substance Abuse, and Alcohol Dependence. …
Matched Description: … Carisbamate has been investigated in Alcohol Abuse, Substance Abuse, and Alcohol Dependence. …
Staurosporine
An indolocarbazole that is a potent protein kinase C inhibitor which enhances cAMP-mediated responses in human neuroblastoma cells. (Biochem Biophys Res Commun 1995;214(3):1114-20)
Experimental
Matched Iupac: … (2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.1^{2,6}.0^{7,28 …
Matched Description: … indolocarbazole that is a potent protein kinase C inhibitor which enhances cAMP-mediated responses in …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Description: … indolocarbazole that is a potent protein kinase C inhibitor which enhances cAMP-mediated responses in …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
GLPG-1205
GLPG-1205 is under investigation in clinical trial NCT03725852 (A Clinical Study to Test How Effective and Safe GLPG1205 is for Patients With Idiopathic Pulmonary Fibrosis (IPF)).
Investigational
Matched Iupac: … 9-(2-cyclopropylethynyl)-2-{[(2S)-1,4-dioxan-2-yl]methoxy}-4H,6H,7H-pyrimido[4,3-a]isoquinolin-4-one …
Matched Description: … GLPG-1205 is under investigation in clinical trial NCT03725852 (A Clinical Study to Test How Effective …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Description: … GLPG-1205 is under investigation in clinical trial NCT03725852 (A Clinical Study to Test How Effective …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Displaying drugs 13626 - 13650 of 13829 in total