Displaying drugs 13851 - 13875 of 14019 in total
AG0302-COVID19
Sponsored by Anges, Inc. in Japan, the AG0302-COVID19 is a DNA-based vaccine that recently completed Phase I/II trials (NCT04527081)[A226813, L30548].
Investigational
Matched Description: … Sponsored by Anges, Inc. in Japan, the AG0302-COVID19 is a DNA-based vaccine that recently completed …
(S)-Fluoxetine
An N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine that has S configuration (the antidepressant drug fluoxetine is a racemate comprising equimolar amounts of (R)- and (S)-fluoxetine).
Experimental
Matched Description: … has S configuration (the antidepressant drug fluoxetine is a racemate comprising equimolar amounts of …
FB-101
FB-101 is a c-Abl inhibitor. Developed by 1st Biotherapeutics, it is being investigated for the treatment of neurological disorders, such as Parkinson's Disease and amyotrophic lateral sclerosis (ALS).
Experimental
Investigational
Matched Description: … Developed by 1st Biotherapeutics, it is being investigated for the treatment of neurological disorders …
AMG-553
AMG-553 is an adoptive, anti-FLT3 chimeric antigen receptor T-cell therapy generated through transduction of autologous T-cells with a self-inactivating human immunodeficiency virus-1 based lentiviral vector.
Investigational
Matched Description: … 553 is an adoptive, anti-FLT3 chimeric antigen receptor T-cell therapy generated through transduction of …
Cyclopropane
Cyclopropane was initially investigated because it was thought to be the toxic element in ethylene. Instead, it turned out to be an excellent anesthetic with very rapid onset and recovery while maintaining stable hemodynamics. Its use was ultimately limited because it was highly explosive.
Experimental
Matched Description: … Cyclopropane was initially investigated because it was thought to be the toxic element in ethylene. …
Putrescine
Putrescine is a toxic diamine formed by putrefaction from the decarboxylation of arginine and ornithine. Putrescine is a solid. This compound belongs to the polyamines. These are compounds containing more than one amine group. Known drug targets of putrescine include putrescine-binding periplasmic protein, ornithine decarboxylase, and S-adenosylmethionine decarboxylase proenzyme.
Experimental
Matched Description: … Putrescine is a toxic diamine formed by putrefaction from the decarboxylation of arginine and ornithine ... Known drug targets of putrescine include putrescine-binding periplasmic protein, ornithine decarboxylase …
ARO-APOC3
ARO-APOC3 is an investigational RNAi therapeutic targeting apolipoprotein C-III (APOC3). It received an Orphan Drug designation by the FDA for the treatment of familial chylomicronemia syndrome.
Investigational
Matched Description: … It received an Orphan Drug designation by the FDA for the treatment of familial chylomicronemia syndrome …
Vixotrigine
Vixotrigine has been investigated for the treatment of Bipolar Disorder and Bipolar Depression.
Investigational
Matched Iupac: … (2S,5R)-5-{4-[(2-fluorophenyl)methoxy]phenyl}pyrrolidine-2-carboxamide …
Matched Description: … Vixotrigine has been investigated for the treatment of Bipolar Disorder and Bipolar Depression. …
Matched Description: … Vixotrigine has been investigated for the treatment of Bipolar Disorder and Bipolar Depression. …
Avagacestat
Avagacestat has been investigated for the basic science and treatment of Alzheimer Disease.
Investigational
Matched Iupac: … (2R)-5,5,5-trifluoro-2-(N-{[2-fluoro-4-(1,2,4-oxadiazol-3-yl)phenyl]methyl}4-chlorobenzenesulfonamido …
Matched Description: … Avagacestat has been investigated for the basic science and treatment of Alzheimer Disease. …
Matched Description: … Avagacestat has been investigated for the basic science and treatment of Alzheimer Disease. …
BMS-777607
BMS-777607 has been investigated for the basic science of Malignant Solid Tumour.
Investigational
Matched Iupac: … N-{4-[(2-amino-3-chloropyridin-4-yl)oxy]-3-fluorophenyl}-4-ethoxy-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine …
Matched Description: … BMS-777607 has been investigated for the basic science of Malignant Solid Tumour. …
Matched Description: … BMS-777607 has been investigated for the basic science of Malignant Solid Tumour. …
Tanezumab
Tanezumab has been investigated for the treatment of Osteoarthritis, Knee and Neuralgia, Postherpetic.
Investigational
Matched Description: … Tanezumab has been investigated for the treatment of Osteoarthritis, Knee and Neuralgia, Postherpetic …
Barium
Barium is under investigation for the diagnostic of Known or Suspected Abdominal Disease.
Investigational
Matched Description: … Barium is under investigation for the diagnostic of Known or Suspected Abdominal Disease. …
ASP-7317
ASP-7317 consists of human embryonic stem cell-derived retinal pigment epithelium cells.
Investigational
Matched Description: … ASP-7317 consists of human embryonic stem cell-derived retinal pigment epithelium cells. …
Butyrylcholinesterase
Investigational
Tropatepine
Tropatepine has been used in France for its antiparkinsons activities .
Experimental
Matched Iupac: … (1R,5S)-8-methyl-3-{9-thiatricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3(8),4,6,11,13-hexaen-2-ylidene}-8-azabicyclo …
Matched Description: … Tropatepine has been used in France for its antiparkinsons activities [A175024]. …
Matched Description: … Tropatepine has been used in France for its antiparkinsons activities [A175024]. …
BMS-564929
BMS-564929 is an investigational therapeutic agent built to be a selective androgen receptor modulator (SARM). So far, it has been developed by Bristol-Myers Squibb for the symptomatic treatment of andropause.
Experimental
Matched Iupac: … 4-[(7R,7aS)-7-hydroxy-1,3-dioxo-hexahydro-1H-pyrrolo[1,2-c]imidazol-2-yl]-2-chloro-3-methylbenzonitrile …
Matched Description: … So far, it has been developed by Bristol-Myers Squibb for the symptomatic treatment of andropause. …
Matched Description: … So far, it has been developed by Bristol-Myers Squibb for the symptomatic treatment of andropause. …
TBX-3400
TBX-3400 is an investigational cell-based immunotherapy consisting of autologous peripheral blood mononuclear cells (PBMCs) treated ex vivo with TBX-4000, which is a recombinant TAT-MYC fusion protein.[L44281,L44286]
Investigational
Matched Description: … TBX-3400 is an investigational cell-based immunotherapy consisting of autologous peripheral blood mononuclear …
DCVAC/OvCa
DCVAC/OvCa is a therapy comprising autologous dendritic cells pulsed with killed ovarian cancer cells and matured by TLR3 ligand ex vivo. It is under investigation for the treatment of ovarian cancer.
Investigational
Matched Description: … It is under investigation for the treatment of ovarian cancer. …
Acetic acid C-11
Acetic acid C-11 is under investigation in clinical trial NCT01953965 (Look at Way the Heart Functions in People With Pulmonary Hypertension (PH) Who Have Near Normal Right Ventricle (RV) Function and People With Pulmonary Hypertension Who Have Impaired RV Function. Using Imaging Studies PET Scan and Cardiac MRI.).
Investigational
Matched Description: … Acetic acid C-11 is under investigation in clinical trial NCT01953965 (Look at Way the Heart Functions ... in People With Pulmonary Hypertension (PH) Who Have Near Normal Right Ventricle (RV) Function and People …
Ricolinostat
Ricolinostat is under investigation for the treatment of Breast Carcinoma and Metastatic Breast Cancer.
Investigational
Matched Iupac: … 7-{[2-(diphenylamino)pyrimidin-5-yl]formamido}-N-hydroxyheptanamide …
Matched Description: … Ricolinostat is under investigation for the treatment of Breast Carcinoma and Metastatic Breast Cancer …
Matched Description: … Ricolinostat is under investigation for the treatment of Breast Carcinoma and Metastatic Breast Cancer …
GSK-1004723
Gsk1004723 has been investigated for the treatment of Allergic Rhinitis and Rhinitis, Allergic, Seasonal.
Investigational
Matched Iupac: … 2-{[(2R)-1-(4-{4-[3-(azepan-1-yl)propoxy]phenyl}butyl)pyrrolidin-2-yl]methyl}-4-[(4-chlorophenyl)methyl …
Matched Description: … Gsk1004723 has been investigated for the treatment of Allergic Rhinitis and Rhinitis, Allergic, Seasonal …
Matched Description: … Gsk1004723 has been investigated for the treatment of Allergic Rhinitis and Rhinitis, Allergic, Seasonal …
Rotigaptide
Rotigaptide is under investigation for the basic science of Heart Disease and Vascular Disease.
Investigational
Matched Iupac: … (2R)-N-(carbamoylmethyl)-2-(2-{[(2R,4S)-1-[(2R)-1-[(2R)-2-acetamido-3-(4-hydroxyphenyl)propanoyl]pyrrolidine ... -2-carbonyl]-4-hydroxypyrrolidin-2-yl]formamido}acetamido)propanamide …
Matched Description: … Rotigaptide is under investigation for the basic science of Heart Disease and Vascular Disease. …
Matched Description: … Rotigaptide is under investigation for the basic science of Heart Disease and Vascular Disease. …
AQ-13
AQ-13 is an 4-aminoquinoline analog being investigated for the treatment of malaria.
Investigational
Matched Description: … AQ-13 is an 4-aminoquinoline analog being investigated for the treatment of malaria. …
AV-0113
AV-0113 consists of IL-12 secreting dendritic cells loaded with autologous tumor lysate.
Investigational
Matched Description: … AV-0113 consists of IL-12 secreting dendritic cells loaded with autologous tumor lysate. …
Carisbamate
Carisbamate has been investigated in Alcohol Abuse, Substance Abuse, and Alcohol Dependence.
Investigational
Matched Iupac: … (2S)-2-(2-chlorophenyl)-2-hydroxyethyl carbamate …
Matched Description: … Carisbamate has been investigated in Alcohol Abuse, Substance Abuse, and Alcohol Dependence. …
Matched Description: … Carisbamate has been investigated in Alcohol Abuse, Substance Abuse, and Alcohol Dependence. …
Displaying drugs 13851 - 13875 of 14019 in total