Displaying drugs 13901 - 13925 of 13944 in total
CVnCoV
The CVnCov Vaccine (or CV07050101) is in development by CureVac AG. The vaccine uses mRNA technology to create a protein associated with SARS-CoV2, and upon administration and replication, to initiate subsequent immune responses in the body. As of June 2020, the company received regulatory approval from German and Belgian Authorities...
Investigational
Matched Synonyms: … SARS-CoV-2 mRNA vaccine …
Matched Description: … The vaccine uses mRNA technology to create a protein associated with SARS-CoV2, and upon administration ... 2020, the company received regulatory approval from German and Belgian Authorities to commence Phase 1 …
Matched Description: … The vaccine uses mRNA technology to create a protein associated with SARS-CoV2, and upon administration ... 2020, the company received regulatory approval from German and Belgian Authorities to commence Phase 1 …
Talarozole
Talarozole has been investigated for the treatment of Psoriasis and Cutaneous Inflammation.
Investigational
Matched Iupac: … N-{4-[2-ethyl-1-(1H-1,2,4-triazol-1-yl)butyl]phenyl}-1,3-benzothiazol-2-amine …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
Dihydroquinidine barbiturate
Experimental
Firocoxib
Firocoxib is a cycooxygenase-2 (COX-2) selective non-steroidal anti-inflammatory drug. It currently approved for veterinary use in dogs and horses under the brand names Equioxx and Previcox. Firocoxib was the first COX-2 inhibitor approved by the U.S. Food and Drug Administration for horses. Firocoxib is not intended or approved for use...
Experimental
Vet approved
Matched Iupac: … 3-(cyclopropylmethoxy)-4-(4-methanesulfonylphenyl)-5,5-dimethyl-2,5-dihydrofuran-2-one …
Matched Description: … Firocoxib is a cycooxygenase-2 (COX-2) selective non-steroidal anti-inflammatory drug. ... Firocoxib was the first COX-2 inhibitor approved by the U.S. …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Selective Cyclooxygenase 2 Inhibitors (NSAIDs) …
Matched Description: … Firocoxib is a cycooxygenase-2 (COX-2) selective non-steroidal anti-inflammatory drug. ... Firocoxib was the first COX-2 inhibitor approved by the U.S. …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Selective Cyclooxygenase 2 Inhibitors (NSAIDs) …
Deracoxib
Deracoxib is a non-steroidal anti-inflammatory drug of the coxib class, used in veterinary medicine to treat osteoarthritis in dogs. It is sold in tablets, which have added beefy flavour to increase palatability. Deramaxx received FDA approval in August 2002 for "the control of post operative pain and inflammation associated with...
Vet approved
Matched Iupac: … 4-[3-(difluoromethyl)-5-(3-fluoro-4-methoxyphenyl)-1H-pyrazol-1-yl]benzene-1-sulfonamide …
Matched Description: … Deracoxib is a non-steroidal anti-inflammatory drug of the coxib class, used in veterinary medicine to …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Description: … Deracoxib is a non-steroidal anti-inflammatory drug of the coxib class, used in veterinary medicine to …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Gaboxadol
Gaboxadol also known as 4,5,6,7-tetrahydroisoxazolo(5,4-c)pyridin-3-ol (THIP) is an experimental sleep aid drug developed by Lundbeck and Merck, who reported increased deep sleep without the reinforcing effects of benzodiazepines. Development of Gaboxadol was stopped in March 2007 after concerns regarding safety and efficacy. It acts on the GABA system, but in...
Investigational
Matched Synonyms: … 4,5,6,7-tetrahydroisoxazolo(5,4-c)pyridin-3-ol …
Matched Iupac: … 2H,3H,4H,5H,6H,7H-[1,2]oxazolo[5,4-c]pyridin-3-one …
Matched Description: … Gaboxadol also known as 4,5,6,7-tetrahydroisoxazolo(5,4-c)pyridin-3-ol (THIP) is an experimental sleep ... It acts on the GABA system, but in a seemingly different way from benzodiazepines and other sedatives …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … 2H,3H,4H,5H,6H,7H-[1,2]oxazolo[5,4-c]pyridin-3-one …
Matched Description: … Gaboxadol also known as 4,5,6,7-tetrahydroisoxazolo(5,4-c)pyridin-3-ol (THIP) is an experimental sleep ... It acts on the GABA system, but in a seemingly different way from benzodiazepines and other sedatives …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
RG-7795
Investigational
Matched Iupac: … (2R,3R,5S)-2-{5-amino-2-oxo-2H,3H-[1,3]thiazolo[4,5-d]pyrimidin-3-yl}-5-(hydroxymethyl)oxolan-3-yl acetate …
Banoxantrone
Banoxantrone is a highly selective bioreductive drug that is activated in, and is preferentially toxic to, hypoxic cells in tumours. It has been shown to work synergistically with fractionated radiation to significantly delay growth of tumours compared to administration of either banoxantrone or radiation alone. Banoxantrone was also efficacious in...
Investigational
Matched Iupac: … 2-[(4-{[2-(dimethyl-oxo-$l^{5}-azanyl)ethyl]amino}-5,8-dihydroxy-9,10-dioxo-9,10-dihydroanthracen-1-yl ... )amino]-N,N-dimethylethanamine oxide …
Matched Description: … Banoxantrone is a highly selective bioreductive drug that is activated in, and is preferentially toxic …
Matched Description: … Banoxantrone is a highly selective bioreductive drug that is activated in, and is preferentially toxic …
CVnCoV Vaccine
The CVnCov Vaccine (or CV07050101) is in development by CureVac AG. The vaccine uses mRNA technology to create a protein associated with SARS-CoV2, and upon administration and replication, to initiate subsequent immune responses in the body. As of June 2020, the company received regulatory approval from German and Belgian Authorities...
Investigational
Matched Description: … The vaccine uses mRNA technology to create a protein associated with SARS-CoV2, and upon administration ... 2020, the company received regulatory approval from German and Belgian Authorities to commence Phase 1 …
Phenaridine
Phenaridine (2,5-Dimethylfentanyl) is a synthetic fentanyl derivative opioid. It was developed in 1972, and is used for surgical anasthesia in Russia. Phenaridine has similar effects to fentanyl. In rat studies, it was less potent than fentanyl. Side effects include itching, nausea and serious to life threatening respiratory depression. Fentanyl analogs...
Illicit
Matched Iupac: … N-[2,5-dimethyl-1-(2-phenylethyl)piperidin-4-yl]-N-phenylpropanamide …
Matched Description: … Phenaridine (2,5-Dimethylfentanyl) is a synthetic fentanyl derivative opioid. …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Description: … Phenaridine (2,5-Dimethylfentanyl) is a synthetic fentanyl derivative opioid. …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Bombesin
Bombesin is under investigation in clinical trial NCT01205321 (PET/CT Imaging for Radiation Dosimetry, Plasma Pharmacokinetics, Biodistribution, Safety and Tolerability and Diagnostic Performance of BAY86-7548 in Patients With Prostate Cancer and Healthy Volunteers).
Investigational
Matched Iupac: … }butanamido]pentanamido]-4-methylpentanamido]acetamido}-3-carbamoylpropanamido]-N-[(1S)-1-{[(1S)-1-{[ ... (1S)-1-[({[(1S)-1-{[(1S)-1-{[(1S)-1-carbamoyl-3-(methylsulfanyl)propyl]carbamoyl}-3-methylbutyl]carbamoyl ... 1H-indol-3-yl)ethyl]pentanediamide ... (2S)-2-[(2S)-2-{2-[(2S)-2-[(2S)-5-carbamimidamido-2-[(2S)-4-carbamoyl-2-{[(2S)-5-oxopyrrolidin-2-yl]formamido ... }-2-(1H-imidazol-4-yl)ethyl]carbamoyl}methyl)carbamoyl]-2-methylpropyl]carbamoyl}ethyl]carbamoyl}-2-( …
Matched Salts cas: … 33910-70-2 …
Matched Salts cas: … 33910-70-2 …
Semapimod
Semapimod has been used in trials studying the treatment of Crohn Disease.
Investigational
Matched Iupac: … N,N'-bis({3,5-bis[(1E)-1-(carbamimidamidoimino)ethyl]phenyl})decanediamide …
Matched Salts cas: … 872830-80-3 ... 164301-51-3 …
Matched Salts cas: … 872830-80-3 ... 164301-51-3 …
Vixotrigine
Vixotrigine has been investigated for the treatment of Bipolar Disorder and Bipolar Depression.
Investigational
Matched Iupac: … (2S,5R)-5-{4-[(2-fluorophenyl)methoxy]phenyl}pyrrolidine-2-carboxamide …
Tosufloxacin
Investigational
Matched Iupac: … 7-(3-aminopyrrolidin-1-yl)-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic …
Matched Salts cas: … 1400591-39-0 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Salts cas: … 1400591-39-0 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Chinese cinnamon
Experimental
Telcagepant
Telcagepant has been investigated for the treatment of Migraine. It is an antagonist of the receptor for calcitonin gene-related peptide (CGRP), a primary neuropeptide involved in the pathophysiology of migraine. CGRP and its receptors are found in areas of the central and peripheral nervous system that are important for the...
Investigational
Matched Iupac: … N-[(3R,6S)-6-(2,3-difluorophenyl)-2-oxo-1-(2,2,2-trifluoroethyl)azepan-3-yl]-4-{2-oxo-1H,2H,3H-imidazo ... [4,5-b]pyridin-1-yl}piperidine-1-carboxamide …
Matched Description: … It is an antagonist of the receptor for calcitonin gene-related peptide (CGRP), a primary neuropeptide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Description: … It is an antagonist of the receptor for calcitonin gene-related peptide (CGRP), a primary neuropeptide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Famprofazone
Famprofazone is a nonsteroidal anti-inflammatory agent found in combination products such as ‘Gewodin’ which is marketed in Taiwan. It is important to note that the drug is metabolized to methamphetamine and amphetamine in the body and can lead to positive tests results for illicit drug use.[A236369,L34724] Famprofazone is included in...
Experimental
Matched Iupac: … 1-methyl-5-{[methyl(1-phenylpropan-2-yl)amino]methyl}-2-phenyl-4-(propan-2-yl)-2,3-dihydro-1H-pyrazol ... -3-one …
Matched Description: … Famprofazone is a nonsteroidal anti-inflammatory agent found in combination products such as ‘Gewodin …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Description: … Famprofazone is a nonsteroidal anti-inflammatory agent found in combination products such as ‘Gewodin …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Mirfentanil
Mirfentanil is a derivative of fentanyl that presents high selectivity for the mu opioid receptor. At lower doses, it antagonizes the analgesic effects of alfentanil and substitutes for naloxone in morphine-treated monkeys; however, it also reverses naloxone-precipitated withdrawal in pigeons trained to discriminate morphine from naloxone. At high doses, it...
Experimental
Matched Iupac: … N-[1-(2-phenylethyl)piperidin-4-yl]-N-(pyrazin-2-yl)furan-2-carboxamide …
Matched Description: … Mirfentanil is a derivative of fentanyl that presents high selectivity for the mu opioid receptor. …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Description: … Mirfentanil is a derivative of fentanyl that presents high selectivity for the mu opioid receptor. …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
DDP-200
DDP200 is developed by Dynogen for the treatment of non-incontinent form of overactive bladder (OAB) with particular focus on both male and female patients with urinary frequency, urinary urgency and nocturia.
Investigational
Lefradafiban
Lefradafiban is an oral platelet glycoprotein IIb/IIIa receptor antagonist being investigated in the treatment of angina.
Investigational
Matched Iupac: … oxopyrrolidin-3-yl]acetate ... methyl 2-[(3S,5S)-5-{[(4'-{[(methoxycarbonyl)amino]methanimidoyl}-[1,1'-biphenyl]-4-yl)oxy]methyl}-2- …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Pyridoxamine
Pyridoxamine has been used in trials studying the treatment of Kidney Stones.
Investigational
Matched Iupac: … 4-(aminomethyl)-5-(hydroxymethyl)-2-methylpyridin-3-ol …
Matched Categories: … Vitamin B Complex ... Heterocyclic Compounds, 1-Ring …
Matched Categories: … Vitamin B Complex ... Heterocyclic Compounds, 1-Ring …
Displaying drugs 13901 - 13925 of 13944 in total