Displaying drugs 1376 - 1400 of 1825 in total
Para-Iodo-D-Phenylalanine Hydroxamic Acid
Experimental
Matched Name: … Para-Iodo-D-Phenylalanine Hydroxamic Acid …
5-beta-D-ribofuranosylnicotinamide adenine dinucleotide
Experimental
Matched Name: … 5-beta-D-ribofuranosylnicotinamide adenine dinucleotide …
N-[Tosyl-D-Prolinyl]Amino-Ethanethiol
Experimental
Matched Name: … N-[Tosyl-D-Prolinyl]Amino-Ethanethiol …
N-[(4-methoxyphenyl)sulfonyl]-D-alanine
Experimental
Matched Name: … N-[(4-methoxyphenyl)sulfonyl]-D-alanine …
Zonisamide
Zonisamide is a sulfonamide anticonvulsant used as an adjunctive therapy in adults with partial-onset seizures.[L42530,L42535] Zonisamide may act by blocking repetitive firing of voltage-gated sodium channels, leading to a reduction of T-type calcium channel currents or by binding allosterically to GABA receptors. This latter action may inhibit the uptake of...
Approved
Investigational
Matched Synonyms: … Benzo[d]isoxazol-3-yl-methanesulfonamide …
Matched Description: … The US and Europe approved it in 2000 and 2005, respectively.[A1379,A1383] …
Matched Categories: … Calcium-Regulating Hormones and Agents …
Matched Products: … ZONISAMIDE DOC GENERICI …
Matched Description: … The US and Europe approved it in 2000 and 2005, respectively.[A1379,A1383] …
Matched Categories: … Calcium-Regulating Hormones and Agents …
Matched Products: … ZONISAMIDE DOC GENERICI …
Antimony potassium tartrate
Antimony potassium tartrate is a schistosomicide possibly useful against other parasites. It has irritant emetic properties and may cause lethal cardiac toxicity among other adverse effects.
Experimental
Matched Synonyms: … Potassium antimonyl D-tartrate …
Matched Description: … It has irritant emetic properties and may cause lethal cardiac toxicity among other adverse effects. …
Matched Description: … It has irritant emetic properties and may cause lethal cardiac toxicity among other adverse effects. …
Teniposide
Teniposide is a semisynthetic derivative of podophyllotoxin that exhibits antitumor activity. Teniposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA. This complex induces breaks in double stranded DNA and prevents repair by topoisomerase II binding. Accumulated breaks in DNA prevent cells from entering into the mitotic...
Approved
Matched Synonyms: … 4'-demethylepipodophyllotoxin 9-(4,6-O-(R)-2-thenylidene-beta-D-glucopyranoside) …
Matched Iupac: … 10R,11R,15R,16S)-16-{[(2R,4aR,6R,7R,8R,8aS)-7,8-dihydroxy-2-(thiophen-2-yl)-hexahydro-2H-pyrano[3,2-d] ... [1,3]dioxin-6-yl]oxy}-10-(4-hydroxy-3,5-dimethoxyphenyl)-4,6,13-trioxatetracyclo[7.7.0.0^{3,7}.0^{11,15 …
Matched Description: … Teniposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA. ... This complex induces breaks in double stranded DNA and prevents repair by topoisomerase II binding. ... Accumulated breaks in DNA prevent cells from entering into the mitotic phase of the cell cycle, and lead …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Iupac: … 10R,11R,15R,16S)-16-{[(2R,4aR,6R,7R,8R,8aS)-7,8-dihydroxy-2-(thiophen-2-yl)-hexahydro-2H-pyrano[3,2-d] ... [1,3]dioxin-6-yl]oxy}-10-(4-hydroxy-3,5-dimethoxyphenyl)-4,6,13-trioxatetracyclo[7.7.0.0^{3,7}.0^{11,15 …
Matched Description: … Teniposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA. ... This complex induces breaks in double stranded DNA and prevents repair by topoisomerase II binding. ... Accumulated breaks in DNA prevent cells from entering into the mitotic phase of the cell cycle, and lead …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
AVR-48
Investigational
Matched Synonyms: … 4-nitrophenyl-n-acetyl-beta-d-glucosaminide ... -d-glucopyranoside, 4-nitrophenyl 2-(acetylamino)-2-deoxy- ... 4-nitrophenyl 2-acetamido-2-deoxy-beta-d-glucopyranoside …
Phenprocoumon
Coumarin derivative that acts as a long-acting oral anticoagulant.
Approved
Investigational
Matched Synonyms: … 3-(alpha-Ethylbenzyl)-4-hydroxycoumarin ... 3-(alpha-Phenylpropyl)-4-hydroxycoumarin …
Matched Categories: … Blood and Blood Forming Organs …
Matched Categories: … Blood and Blood Forming Organs …
sn-glycerol 3-phosphate
Experimental
Matched Synonyms: … D-Glycerol 1-phosphate ... D-(glycerol 1-phosphate) …
Mitiperstat
Mitiperstat is under investigation in clinical trial NCT05492877 (An Efficacy and Safety Study of Mitiperstat (AZD4831) (MPO Inhibitor) vs Placebo in the Treatment of Moderate to Severe COPD.).
Investigational
Matched Synonyms: … 1-({2-[(1R)-1-aminoethyl]-4-chlorophenyl}methyl)-2-sulfanylidene-1,2,3,5-tetrahydro-4H-pyrrolo[3,2-d] ... 4H-Pyrrolo[3,2-d]pyrimidin-4-one, 1-[[2-[(1R)-1-aminoethyl]-4-chlorophenyl]methyl]-1,2,3,5-tetrahydro …
Matched Description: … Mitiperstat is under investigation in clinical trial NCT05492877 (An Efficacy and Safety Study of Mitiperstat …
Matched Description: … Mitiperstat is under investigation in clinical trial NCT05492877 (An Efficacy and Safety Study of Mitiperstat …
Serine
A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from glycine or threonine. It is involved in the biosynthesis of purines; pyrimidines; and other amino acids.
Investigational
Nutraceutical
Matched Synonyms: … alpha-Amino-beta-hydroxypropionic acid …
Matched Description: … It is involved in the biosynthesis of purines; pyrimidines; and other amino acids. …
Matched Mixtures name: … Aminosyn II and Dextrose ... Aminosyn II and Dextrose ... Amino Acid InJ.W.elecw.25%dex …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … It is involved in the biosynthesis of purines; pyrimidines; and other amino acids. …
Matched Mixtures name: … Aminosyn II and Dextrose ... Aminosyn II and Dextrose ... Amino Acid InJ.W.elecw.25%dex …
Matched Categories: … Amino Acids, Peptides, and Proteins …
PD173955
Experimental
Matched Synonyms: … 6-(2,6-dichlorophenyl)-8-methyl-2-{[3-(methylthio)phenyl]amino}pyrido[2,3-d]pyrimidin-7(8H)-one …
Matched Iupac: … 6-(2,6-dichlorophenyl)-8-methyl-2-{[3-(methylsulfanyl)phenyl]amino}-7H,8H-pyrido[2,3-d]pyrimidin-7-one …
Matched Iupac: … 6-(2,6-dichlorophenyl)-8-methyl-2-{[3-(methylsulfanyl)phenyl]amino}-7H,8H-pyrido[2,3-d]pyrimidin-7-one …
3-[2,6,8-Trioxo-9-[(2R,3R,4R)-2,3,4,5-tetrahydroxypentyl]-3H-purin-7-yl]propyl dihydrogen phosphate
Experimental
Matched Synonyms: … 5-Deoxy-5-{2,6,8-trioxo-7-[3-(phosphonooxy)propyl]-1,2,3,6,7,8-hexahydro-9H-purin-9-yl}-D-arabinitol …
Vilamakitug
Vilamakitug is under investigation in clinical trial NCT05201352 (Evaluation of Efficacy of Trifluridine/tipiracil Plus an Anti-il-1α True Human Antibody Versus Trifluridine/tipiracil Plus Placebo in Metastatic Colorectal Cancer Patients After Failure of Oxaliplatin, Irinotecan, Fluoropyrimidine).
Investigational
Matched Synonyms: … Immunoglobulin g4, anti-(human interleukin 1.alpha.) …
Denfivontinib
Investigational
Matched Synonyms: … 8-Bromo-2-((1-methylpiperidin-4-yl)amino)-4-((4-phenoxyphenyl)amino)pyrido[4,3-D]pyrimidin-5(6H)-one ... 8-bromo-2-[(1-methylpiperidin-4-yl)amino]-4-(4-phenoxyanilino)-6H-pyrido[4,3-d]pyrimidin-5-one …
Matched Iupac: … 8-bromo-2-[(1-methylpiperidin-4-yl)amino]-4-[(4-phenoxyphenyl)amino]-5H,6H-pyrido[4,3-d]pyrimidin-5-one …
Matched Iupac: … 8-bromo-2-[(1-methylpiperidin-4-yl)amino]-4-[(4-phenoxyphenyl)amino]-5H,6H-pyrido[4,3-d]pyrimidin-5-one …
Belvarafenib
Investigational
Matched Synonyms: … 4-amino-n-(1-((3-chloro-2-fluorophenyl)amino)-6-methylisoquinolin-5-yl)thieno(3,2-d)pyrimidine-7-carboxamide ... Thieno(3,2-d)pyrimidine-7-carboxamide, 4-amino-n-(1-((3-chloro-2-fluorophenyl)amino)-6-methyl-5-isoquinolinyl …
Matched Iupac: … 4-amino-N-{1-[(3-chloro-2-fluorophenyl)amino]-6-methylisoquinolin-5-yl}thieno[3,2-d]pyrimidine-7-carboxamide …
Matched Iupac: … 4-amino-N-{1-[(3-chloro-2-fluorophenyl)amino]-6-methylisoquinolin-5-yl}thieno[3,2-d]pyrimidine-7-carboxamide …
Azacitidine
Azacitidine is a pyrimidine nucleoside analogue with anti-neoplastic activity. It differs from cytosine by the presence of nitrogen in the C5-position, key in its hypomethylating activity.[A1406,A1413,A1415] Two main mechanisms of action have been proposed for azacitidine. One of them is the induction of cytotoxicity. As an analogue of cytidine, it...
Approved
Investigational
Matched Synonyms: … 4-amino-1-beta-D-ribofuranosyl-s-triazin-2(1H)-one …
Matched Description: … inhibiting protein and DNA synthesis. ... [A1407] Due to its anti-neoplastic activity and its ability to inhibit methylation in replicating DNA ... As an analogue of cytidine, it is able to incorporate into RNA and DNA, disrupting RNA metabolism and …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Nucleic Acids, Nucleotides, and Nucleosides …
Matched Description: … inhibiting protein and DNA synthesis. ... [A1407] Due to its anti-neoplastic activity and its ability to inhibit methylation in replicating DNA ... As an analogue of cytidine, it is able to incorporate into RNA and DNA, disrupting RNA metabolism and …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Nucleic Acids, Nucleotides, and Nucleosides …
Iothalamic acid
Iothalamic acid is an iodine containing organic anion used as a diagnostic contrast agent.
Approved
Matched Synonyms: … 1-deoxy-1-(methylamino)-D-glucitol 5-acetamido-2,4,6 triiodo-N-methylisophthalamate …
Histidine
An essential amino acid that is required for the production of histamine.
Investigational
Nutraceutical
Matched Synonyms: … (S)-alpha-amino-1H-Imidazole-4-propanoic acid ... (S)-alpha-Amino-1H-imidazole-4-propionic acid …
Matched Mixtures name: … Aminosyn II and Dextrose ... Aminosyn II and Dextrose ... Amino Acid InJ.W.elecw.25%dex …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Mixtures name: … Aminosyn II and Dextrose ... Aminosyn II and Dextrose ... Amino Acid InJ.W.elecw.25%dex …
Matched Categories: … Amino Acids, Peptides, and Proteins …
TAK-733
TAK-733 has been used in trials studying the treatment of Advanced Metastatic Melanoma, Advanced Nonhematologic Malignancies, and Advanced Non-hematologic Malignancies.
Investigational
Matched Synonyms: … (R)-3-(2,3-DIHYDROXYPROPYL)-6-FLUORO-5-(2-FLUORO-4-IODOPHENYLAMINO)-8-METHYLPYRIDO(2,3-D)PYRIMIDINE-4,7 ... 3-[(2R)-2,3-dihydroxypropyl]-6-fluoro-5-[(2-fluoro-4-iodophenyl)amino]-8-methylpyrido[2,3-d]pyrimidine …
Matched Iupac: … (2R)-2,3-dihydroxypropyl]-6-fluoro-5-[(2-fluoro-4-iodophenyl)amino]-8-methyl-3H,4H,7H,8H-pyrido[2,3-d] …
Matched Description: … trials studying the treatment of Advanced Metastatic Melanoma, Advanced Nonhematologic Malignancies, and …
Matched Iupac: … (2R)-2,3-dihydroxypropyl]-6-fluoro-5-[(2-fluoro-4-iodophenyl)amino]-8-methyl-3H,4H,7H,8H-pyrido[2,3-d] …
Matched Description: … trials studying the treatment of Advanced Metastatic Melanoma, Advanced Nonhematologic Malignancies, and …
Inavolisib
Inavolisib (GDC-0077) is under investigation in clinical trial NCT03006172 (To Evaluate the Safety, Tolerability, and Pharmacokinetics of GDC-0077 Single Agent in Participants With Solid Tumors and in Combination With Endocrine and Targeted Therapies in Participants With Breast Cancer).
Investigational
Matched Synonyms: … (2S)-2-((2-((4S)-4-(difluoromethyl)-2-oxo-3-oxazolidinyl)-5,6-dihydroimidazo(1,2-D)(1,4)benzoxazepin- ... propanamide, 2-((2-((4S)-4-(difluoromethyl)-2-oxo-3-oxazolidinyl)-5,6-dihydroimidazo(1,2-D)(1,4)benzoxazepin …
Matched Description: … Endocrine and Targeted Therapies in Participants With Breast Cancer). ... GDC-0077) is under investigation in clinical trial NCT03006172 (To Evaluate the Safety, Tolerability, and ... Pharmacokinetics of GDC-0077 Single Agent in Participants With Solid Tumors and in Combination With …
Matched Description: … Endocrine and Targeted Therapies in Participants With Breast Cancer). ... GDC-0077) is under investigation in clinical trial NCT03006172 (To Evaluate the Safety, Tolerability, and ... Pharmacokinetics of GDC-0077 Single Agent in Participants With Solid Tumors and in Combination With …
Domperidone
A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
Approved
Investigational
Vet approved
Matched Synonyms: … 1-(3-(4-(5-chloro-2-oxo-2,3-dihydrobenzo[d]imidazol-1-yl)piperidin-1-yl)propyl)-1H-benzo[d]imidazol-2 ... 5-chloro-1-(1-(3-(2-oxo-2,3-dihydrobenzo[d]imidazol-1-yl)propyl)piperidin-4-yl)-1H-benzo[d]imidazol-2 …
Matched Description: … It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool …
Matched Categories: … Alimentary Tract and Metabolism ... Dopamine D2 Receptor Antagonists …
Matched Products: … DOM ... Dom-domperidone ... DOMPERIDONE DOC GENERICI …
Matched Description: … It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool …
Matched Categories: … Alimentary Tract and Metabolism ... Dopamine D2 Receptor Antagonists …
Matched Products: … DOM ... Dom-domperidone ... DOMPERIDONE DOC GENERICI …
TG01 vaccine
Investigational
Matched Synonyms: … -V-p21 RAS(5-21). 13-D-p21 RAS(5-21) ... 12-A-p21 RAS(5-21). 12-C-p21 RAS(5-21). 12-D-p21 RAS(5-21). 12-Rp21 RAS(5-21). 12-S-p21 RAS(5-21). 12 …
Displaying drugs 1376 - 1400 of 1825 in total