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Displaying drugs 1376 - 1400 of 9542 in total
Tramadol is a centrally acting synthetic opioid analgesic and SNRI (serotonin/norepinephrine reuptake-inhibitor) that is structurally related to codeine and morphine. Due to its good tolerability profile and multimodal mechanism of action, tramadol is generally considered a lower-risk opioid option for the treatment of moderate to severe pain. It is considered...
Approved
Investigational
Matched Iupac: … 2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexan-1-ol …
Matched Description: … It is considered a Step 2 option on the World Health Organization's pain ladder and has about 1/10th …
Matched Mixtures name: … DOR-2® ... Theratramadol-60
Matched Products: … TRAMASINDOL 50 MG /1 ML ... TRAMADOL CLORHIDRATO 50 MG/ 1 ML ... TRAMADOL CLORHIDRATO AMPOLLAS 50 MG / 1 ML. …
Dorzolamide is a non-bacteriostatic sulfonamide derivative and topical carbonic anhydrase (CA) inhibitor that treats elevated intraocular pressure (IOP) associated with open-angle glaucoma and ocular hypertension. It works by blocking an enzyme in the ciliary process that regulates ion balance and fluid pressure in the eyes. Unlike oral CA inhibitors, dorzolamide...
Approved
Matched Synonyms: … (4S,6S)-4-ethylamino-6-methyl-7,7-dioxo-4,5,6,7-tetrahydro-7lambda*6*-thieno[2,3-b]thiopyran-2-sulfonic ... (4S,trans)-4-(ethylamino)-6-methyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide ... 4-Ethylamino-6-methyl-7,7-dioxo-4,5,6,7-tetrahydro-7lambda*6*-thieno[2,3-b]thiopyran-2-sulfonic acid …
Matched Iupac: … (2S,4S)-4-(ethylamino)-2-methyl-1,1-dioxo-2H,3H,4H-1lambda6-thieno[2,3-b]thiopyran-6-sulfonamide …
Matched Salts cas: … 130693-82-2
Matched Mixtures name: … XOLATIM %2+ %0,5 GÖZ DAMLASI, ÇÖZELTİ ,5 ML,1 ŞİŞE ... DORZASOPT GÖZ DAMLASI ,1 ŞIŞE ... DUOSOPT FREE 20 MG+5 MG/ML GÖZ DAMLASI, ÇÖZELTİ, 60 ADET …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … DORZAMED %2 GÖZ DAMLASI ,1 ŞIŞE ... XOLADOR %2 GÖZ DAMLASI ,5 ML, 1 ŞIŞE ... TRUVEX EYE DROPS 2% W/V …
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Vibegron is a potent, selective beta-3 adrenergic receptor (β3) agonist that relaxes the detrusor smooth muscle of the bladder, thereby increasing bladder capacity. Vibegron was first approved in Japan in September 2018 for the treatment of overactive bladder, a condition associated with distressing symptoms of urge urinary incontinence, urgency, and...
Approved
Investigational
Matched Iupac: … [1,2-a]pyrimidine-6-carboxamide ... (6S)-N-(4-{[(2S,5R)-5-[(R)-hydroxy(phenyl)methyl]pyrrolidin-2-yl]methyl}phenyl)-4-oxo-4H,6H,7H,8H-pyrrolo …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Pertuzumab is a recombinant humanized monoclonal antibody that targets the extracellular dimerization domain (subdomain II) of the human epidermal growth factor receptor 2 protein (HER2). It consists of two heavy chains and two lights chains that have 448 and 214 residues respectively. It was first approved by the FDA in...
Approved
Matched Description: … the extracellular dimerization domain (subdomain II) of the human epidermal growth factor receptor 2
Matched Categories: … Receptor, ErbB-2, antagonists & inhibitors ... HER2 (Human Epidermal Growth Factor Receptor 2) inhibitors …
2,2'-Dibenzothiazyl disulfide is an accelerator used in the processing process for natural and synthetic rubber and plastic regeneration. It is also a known allergen and dermatological sensitizer. Sensitivity to 2,2'-Dibenzothiazyl disulfide may be identified with a clinical patch test.
Approved
Experimental
Matched Synonyms: … 2-Benzothiazolyl disulfide ... 2-Mercaptobenzothiazole disulfide ... Bis(2-benzothiazyl) disulfide …
Matched Iupac: … 2-(1,3-benzothiazol-2-yldisulfanyl)-1,3-benzothiazole …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
Xamoterol is a β1-adrenoceptor partial agonist that has shown to improve systolic and diastolic function in studies with heart failure patients. It modulates the sympathetic control of the heart but has no agonist action on β2-adrenoceptors.
Approved
Matched Iupac: … N-(2-{[2-hydroxy-3-(4-hydroxyphenoxy)propyl]amino}ethyl)morpholine-4-carboxamide …
Matched Salts cas: … 90730-93-1
Matched Categories: … Adrenergic beta-1 Receptor Agonists ... Heterocyclic Compounds, 1-Ring …
Aripiprazole is an atypical antipsychotic orally indicated for the treatment of schizophrenia, bipolar I, major depressive disorder, irritability associated with autism, and Tourette's. It is also indicated as an injection for agitation associated with schizophrenia or bipolar mania. Aripiprazole exerts its effects through agonism of dopaminergic and 5-HT1A receptors and...
Approved
Investigational
Matched Iupac: … 7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}-1,2,3,4-tetrahydroquinolin-2-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Adrenergic alpha-1 Receptor Antagonists ... Heterocyclic Compounds, 1-Ring …
Matched Products: … ARİPA 2 MG TABLET, 2 ADET ... ARİPA 2 MG TABLET, 7 ADET ... ARİPA 2 MG TABLET, 28 ADET …
Approved
Experimental
Matched Iupac: … 1-[1,3-bis(hydroxymethyl)-2,5-dioxoimidazolidin-4-yl]-1,3-bis(hydroxymethyl)urea …
Withdrawn from the Canadian, US, and UK markets in 1963 due to interactions with food products containing tyrosine.
Approved
Withdrawn
Matched Synonyms: … 1-(2-(Benzylcarbamoyl)ethyl)-2-isonicotinoylhydrazine ... 2-(2-(Benzylcarbamoyl)ethyl)hydrazide isonicotinic acid ... 2-(2-(Benzylcarbamyl)ethyl)hydrazide isonicotinic acid …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Nicotine is highly toxic alkaloid. It is the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and ultimately blocks synaptic transmission. Nicotine is also important medically because of its presence in tobacco smoke.
Approved
Matched Synonyms: … (S)-3-(1-methylpyrrolidin-2-yl)pyridine ... 3-(2-(N-methylpyrrolidinyl))pyridine ... (S)-3-(N-methylpyrrolidin-2-yl)pyridine …
Matched Iupac: … 3-[(2S)-1-methylpyrrolidin-2-yl]pyridine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … Habitrol Step 1 ... NICOTINE Transdermal System Step 1 ... foster and thrive STEP 1
Ponesimod is a selective sphingosine 1-phosphate receptor 1 modulator indicated in the treatment of relapsing forms of multiple sclerosis in adults.[A232079,L32709] Ponesimod was developed out of a need for a more selective modulator of sphingosine 1-phosphate receptor 1 than fingolimod. Fingolimod's activity at sphingosine 1-phosphate receptor 3 was suspected to...
Approved
Investigational
Matched Iupac: … (2Z,5Z)-5-({3-chloro-4-[(2R)-2,3-dihydroxypropoxy]phenyl}methylidene)-3-(2-methylphenyl)-2-(propylimino …
Matched Description: … Ponesimod is a selective sphingosine 1-phosphate receptor 1 modulator indicated in the treatment of relapsing ... phosphate receptor 1 than [fingolimod]. ... A232079,L32709] Ponesimod was developed out of a need for a more selective modulator of sphingosine 1- …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Sphingosine 1-phosphate Receptor Modulator ... Sphingosine 1 Phosphate Receptor Modulators ... Sphingosine-1-phosphate (S1P) receptor modulators …
Streptomycin, an antibiotic derived from Streptomyces griseus, was the first aminoglycoside to be discovered and used in practice in the 1940s.[A233325,A233390] Selman Waksman and eventually Albert Schatz were recognized with the Nobel Prize in Medicine for their discovery of streptomycin and its antibacterial activity.[A233325,A232294] Although streptomycin was the first antibiotic...
Approved
Vet approved
Matched Synonyms: … 2,4-diguanidino-3,5,6-trihydroxycyclohexyl 5-deoxy-2-O-(2-deoxy-2-methylamino-alpha-L-glucopyranosyl) …
Matched Iupac: … yl]oxy}-4-formyl-4-hydroxy-5-methyloxolan-2-yl]oxy}-2,4,5-trihydroxycyclohexyl]guanidine ... carbamimidamido-6-{[(2R,3R,4R,5S)-3-{[(2S,3S,4S,5R,6S)-4,5-dihydroxy-6-(hydroxymethyl)-3-(methylamino)oxan-2- …
Matched Products: … STREPTOMYCIN SULFATE FOR INJECTION 1 g/vial ... STREPTOMYCIN SULFAT ENJEKTABL FLAKON, 1 ADET ... KRİSTALİZE STREPTOMİSİN SÜLFAT 1 G ENJEKSİYONLUK ÇÖZELTİ TOZU, 50 ADET …
Vasopressin (arginine-vasopressin or antidiuretic hormone) is a nonapeptide primarily produced in the hypothalamus that exhibits diverse physiological functions related to diuresis, hemodynamic modulation, and behaviour.[A110, A111, A112, A113, A228008] Vasopressin is very similar to oxytocin, differing in the third and eighth amino acids. Despite a wide variety of functions, exogenous...
Approved
Matched Iupac: … 2-({1-[19-amino-13-benzyl-10-(2-carbamoylethyl)-7-(carbamoylmethyl)-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18 ... )-5-[(diaminomethylidene)amino]pentanamide; 6-amino-2-({1-[19-amino-13-benzyl-10-(2-carbamoylethyl)-7 ... -pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosane-4-carbonyl]pyrrolidin-2-yl}formamido)-N-(carbamoylmethyl ... -(carbamoylmethyl)-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosane ... -4-carbonyl]pyrrolidin-2-yl}formamido)-N-(carbamoylmethyl)hexanamide …
Matched Description: … /sub> and V2 cellular receptors. ... during systemic shock by increasing vasoconstriction and renal fluid reuptake by acting through V1< …
Matched Salts cas: … 113-79-1
Matched Products: … ./2 ml Konzentrat zur Herstellung einer Infusionslösung …
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Fluoroestradiol F-18 is an imaging agent used with positron emission tomography (PET) to detect estrogen receptor-positive breast cancer lesions. The ability to image ER-positive tumors in vivo is advantageous in that, while helping to visualize tumor progression/regression, it may also be used to assess for heterogeneity in ER expression across...
Approved
Matched Iupac: … (1R,2R,3aS,3bR,9bS,11aS)-2-(¹⁸F)fluoro-11a-methyl-1H,2H,3H,3aH,3bH,4H,5H,9bH,10H,11H,11aH-cyclopenta[ …
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Approved
Matched Synonyms: … Acetic acid, magnesium salt (2:1) …
Matched Iupac: … magnesium(2+) diacetate …
Acetaminophen (paracetamol), also commonly known as Tylenol, is the most commonly taken analgesic worldwide and is recommended as first-line therapy in pain conditions by the World Health Organization (WHO). It is also used for its antipyretic effects, helping to reduce fever. This drug was initially approved by the U.S. FDA...
Approved
Matched Mixtures name: … Adventure Medical Kits 1-2 Person First Aid ... Adventure Medical Kits 1-2 Person National Ski Patrol First Aid ... VICK® FORT-9
Matched Products: … พาราแมน -2 ... PANADOL DROPS 60 mg/0.6 ml ... พานาดอล 0-2
Oxaliplatin is a platinum-based chemotherapy drug in the same family as cisplatin and carboplatin. Compared to cisplatin the two amine groups are replaced by diamino cyclohexane (DACH) group to provide a greater antitumor effect. However, this leads to poorer water solubility, which was compensated by the addition of the chloride...
Approved
Investigational
Matched Iupac: … (3aR,7aR)-octahydro-2',5'-dioxaspiro[cyclohexa[d]1,3-diaza-2-platinacyclopentane-2,1'-cyclopentane]-3 …
Matched Description: … [A797] Oxaliplatin was approved by the FDA on January 9, 2004 and is currently marketed by Sanofi-Aventis …
Matched Products: … OXERIN 2 MG/ML ... OXITAN INJECTION 2 MG/ML ... ICEREN FLAKON, 1 ADET …
Polysilicone-15 is a silicone based UVB absorber [L2796, L2797, L2799, F87, F88, F89]. The compound is a colorless to pale yellow viscous liquid which is soluble in organic solvents of medium polarity and insoluble in water [L2796, L2797, L2799, F87, F88, F89]. It is the first polymeric UVB filer consisting...
Approved
Gemfibrozil is a fibric acid agent, similar to clofibrate, used to treat Type IIb, IV, and V hyperlipidemias.[A185777,L8525] Gemfibrozil is not a first line treatment and is prescribed to patients who have not responded adequately to weight loss, diet, exercise, and other medications. Gemfibrozil was granted FDA approval on 21...
Approved
Aliskiren is the first drug in the renin inhibitor drug class and is used for the treatment of hypertension. It was developed by Speedel and Novartis and initially approved by the FDA in early 2007. Aliskiren has been proven to efficacious in reducing blood pressure when used alone or in...
Approved
Investigational
Matched Iupac: … ]methyl}-8-methyl-2-(propan-2-yl)nonanamide ... (2S,4S,5S,7S)-5-amino-N-(2-carbamoyl-2,2-dimethylethyl)-4-hydroxy-7-{[4-methoxy-3-(3-methoxypropoxy)phenyl …
Matched Salts cas: … 173334-58-2
Displaying drugs 1376 - 1400 of 9542 in total