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Displaying drugs 1426 - 1450 of 6848 in total
Chenodeoxycholic acid
Chenodeoxycholic acid (or Chenodiol) is an epimer of ursodeoxycholic acid (DB01586). Chenodeoxycholic acid is a bile acid naturally found in the body. It works by dissolving the cholesterol that makes gallstones and inhibiting production of cholesterol in the liver and absorption in the intestines, which helps to decrease the formation...
Approved
Matched Iupac: … (4R)-4-[(1R,3aS,3bR,4R,5aS,7R,9aS,9bS,11aR)-4,7-dihydroxy-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta …
Gefitinib
Gefitinib (originally coded ZD1839) is a drug used in the treatment of certain types of cancer. Acting in a similar manner to erlotinib (marketed as Tarceva), gefitinib selectively targets the mutant proteins in malignant cells. It is marketed by AstraZeneca under the trade name Iressa.
Approved
Investigational
Matched Synonyms: … N-(3-chloro-4-fluorophenyl)-7-methoxy-6-(3-(4-morpholinyl)propoxy)-4-quinazolinamine ... 4-(3'-chloro-4'-fluoroanilino)-7-methoxy-6-(3-morpholinopropoxy)quinazoline …
Matched Iupac: … N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[3-(morpholin-4-yl)propoxy]quinazolin-4-amine …
Matched Iupac: … N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[3-(morpholin-4-yl)propoxy]quinazolin-4-amine …
Tirofiban
Tirofiban prevents the blood from clotting during episodes of chest pain or a heart attack, or while the patient is undergoing a procedure to treat a blocked coronary artery. It is a non-peptide reversible antagonist of the platelet glycoprotein (GP) IIb/IIIa receptor, and inhibits platelet aggregation.
Approved
Matched Synonyms: … (2S)-2-(butylsulfonylamino)-3-[4-(4-piperidin-4-ylbutoxy)phenyl]propanoic acid ... N-(Butylsulfonyl)-O-(4-(4-piperidyl)butyl)-L-tyrosine …
Matched Iupac: … (2S)-2-(butane-1-sulfonamido)-3-{4-[4-(piperidin-4-yl)butoxy]phenyl}propanoic acid …
Matched Salts cas: … 150915-40-5 …
Matched Iupac: … (2S)-2-(butane-1-sulfonamido)-3-{4-[4-(piperidin-4-yl)butoxy]phenyl}propanoic acid …
Matched Salts cas: … 150915-40-5 …
Hydrocortisone butyrate
Approved
Vet approved
Matched Synonyms: … 11β,21-dihydroxy-17α-butyryloxy-4-pregnene-3,20-dione …
Hydrocortisone cypionate
Approved
Investigational
Vet approved
Hydrocortisone probutate
Approved
Vet approved
Hydrocortisone valerate
Approved
Vet approved
gamma-Aminobutyric acid
The most common inhibitory neurotransmitter in the central nervous system.
Approved
Investigational
Matched Synonyms: … 4-aminobutanoic acid ... 4-aminobutyric acid …
Matched Iupac: … 4-aminobutanoic acid …
Matched Mixtures name: … Therabenzaprine-90-5 …
Matched Iupac: … 4-aminobutanoic acid …
Matched Mixtures name: … Therabenzaprine-90-5 …
Sorafenib
Sorafenib is a bi-aryl urea and an oral multikinase inhibitor. It targets cell surface tyrosine kinase receptors and downstream intracellular kinases that are implicated in tumour cell proliferation and tumour angiogenesis. First approved by the FDA and European Commission in 2007 for the treatment of hepatocellular carcinoma, sorafenib is also...
Approved
Investigational
Matched Synonyms: … N-(4-Chloro-3-(trifluoromethyl)phenyl)-N'-(4-(2-(N-methylcarbamoyl)-4-pyridyloxy)phenyl)urea ... 4-(4-((((4-Chloro-3-(trifluoromethyl)phenyl)amino)carbonyl)amino)phenoxy)-N-methyl-2-pyridinecarboxamide …
Matched Iupac: … 4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)phenoxy]-N-methylpyridine-2-carboxamide …
Matched Iupac: … 4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)phenoxy]-N-methylpyridine-2-carboxamide …
Tegaserod
Novartis' brand name Zelnorm (tegaserod) had originally received approval from the US FDA in 2002 for the treatment of irritable bowel syndrome with constipation (IBS-C).[L5918,F4229] It was, however, voluntarily withdrawn from widespread use in the US market in 2007 after concerns arose over the possibility that tegaserod could potentially cause...
Approved
Investigational
Withdrawn
Matched Synonyms: … 1-(((5-Methoxyindol-3-yl)methylene)amino)-3-pentylguanidine …
Matched Iupac: … N'-[(E)-[(5-methoxy-1H-indol-3-yl)methylidene]amino]-N-pentylguanidine …
Matched Description: … (5-HT(4)) receptors in smooth muscle cells and in the gastrointestinal wall to facilitate actions like ... remains the only therapy for IBS-C that possesses the unique mechanism of action of acting on serotonin-4 …
Matched Categories: … Serotonin-4 Receptor Agonist ... Serotonin 4 Receptor Agonists ... Serotonin 5-HT2 Receptor Antagonists ... Serotonin 5-HT2A Receptor Antagonists ... Serotonin 5-HT2C Receptor Antagonists …
Matched Iupac: … N'-[(E)-[(5-methoxy-1H-indol-3-yl)methylidene]amino]-N-pentylguanidine …
Matched Description: … (5-HT(4)) receptors in smooth muscle cells and in the gastrointestinal wall to facilitate actions like ... remains the only therapy for IBS-C that possesses the unique mechanism of action of acting on serotonin-4 …
Matched Categories: … Serotonin-4 Receptor Agonist ... Serotonin 4 Receptor Agonists ... Serotonin 5-HT2 Receptor Antagonists ... Serotonin 5-HT2A Receptor Antagonists ... Serotonin 5-HT2C Receptor Antagonists …
Flecainide
Flecainide is a Class I anti-arrhythmic agent like encainide and propafenone. Flecainide’s development began in 1966 and was first synthesized in 1972 as an attempt to generate new anesthetics. It is used to prevent supraventricular and ventricular arrhythmias, as well as paroxysmal atrial fibrillation and flutter.[L8878,L5056]
Flecainide was granted FDA...
Approved
Withdrawn
Matched Salts cas: … 54143-56-5 …
Octisalate
Also known as Ethylhexyl Salicylate. Octyl salicylate is an oil soluble chemical sunscreen agent that absorbs UVB radiation. It does not protect against UVA. Octyl salicylate is used to augment the UVB protection in a sunscreen. Salicylates are weak UVB absorbers and they are generally used in combination with other...
Approved
Investigational
Matched Mixtures name: … Moisture Renew Red Alert (900) ... No-AD Spf30 5 Oz ... OP Dark Tanning Gel 4 …
Scopolamine
Scopolamine is a tropane alkaloid isolated from members of the Solanaceae family of plants, similar to atropine and hyoscyamine, all of which structurally mimic the natural neurotransmitter acetylcholine.[A228423, A228763] Scopolamine was first synthesized in 1959, but to date, synthesis remains less efficient than extracting scopolamine from plants. As an acetylcholine...
Approved
Investigational
Venlafaxine
Venlafaxine is an antidepressant and a serotonin and norepinephrine reuptake inhibitor (SNRI). Its active metabolite, desvenlafaxine, works by blocking the reuptake of serotonin and norepinephrine, which are key neurotransmitters in mood regulation. Venlafaxine is officially approved to treat major depressive disorder (MDD), generalized anxiety disorder (GAD), social anxiety disorder, and...
Approved
Matched Iupac: … 1-[2-(dimethylamino)-1-(4-methoxyphenyl)ethyl]cyclohexan-1-ol …
Matched Salts cas: … 99300-78-4 …
Matched Salts cas: … 99300-78-4 …
Podofilox
A lignan found in podophyllin resin from the roots of podophyllum plants. It is a potent spindle poison, toxic if taken internally, and has been used as a cathartic. It is very irritating to skin and mucous membranes, has keratolytic actions, has been used to treat warts and keratoses, and...
Approved
Matched Iupac: … hydroxy-10-(3,4,5-trimethoxyphenyl)-4,6,13-trioxatetracyclo[7.7.0.0^{3,7}.0^{11,15}]hexadeca-1,3(7),8- …
Dopamine
One of the catecholamine neurotransmitters in the brain. It is derived from tyrosine and is the precursor to norepinephrine and epinephrine. Dopamine is a major transmitter in the extrapyramidal system of the brain, and important in regulating movement. A family of receptors (receptors, dopamine) mediate its action.
Approved
Matched Synonyms: … 4-(2-aminoethyl)catechol ... 4-(2-aminoethyl)pyrocatechol ... 4-(2-aminoethyl)-1,2-benzenediol …
Matched Iupac: … 4-(2-aminoethyl)benzene-1,2-diol …
Matched Mixtures name: … Dopamine HCl 3.2mg/ml Dextrose 5% Inj USP ... Dopamine HCl 1.6mg/ml Dextrose 5% Inj USP ... Dopamine HCl 0.8mg/ml Dextrose 5% Inj USP …
Matched Products: … Dopamine HCl Inj 4% ... ./5มล.) ... PREDOPAM 50 MG/5 ML INF. HAZ. ICIN KON.COZ.ICEREN AMPUL, 5 ADET …
Matched Iupac: … 4-(2-aminoethyl)benzene-1,2-diol …
Matched Mixtures name: … Dopamine HCl 3.2mg/ml Dextrose 5% Inj USP ... Dopamine HCl 1.6mg/ml Dextrose 5% Inj USP ... Dopamine HCl 0.8mg/ml Dextrose 5% Inj USP …
Matched Products: … Dopamine HCl Inj 4% ... ./5มล.) ... PREDOPAM 50 MG/5 ML INF. HAZ. ICIN KON.COZ.ICEREN AMPUL, 5 ADET …
Vadadustat
One of the most common symptoms of advanced renal disease is anemia, caused primarily by the inability of the kidney to respond to anemic conditions with a corresponding increase in erythropoietin (EPO) production. The treatment of anemia associated with chronic kidney disease (CKD) has traditionally involved the administration of exogenous...
Approved
Investigational
Matched Synonyms: … N-(5-(3-Chlorophenyl)-3-hydroxypyridine-2-carbonyl)glycine ... Glycine, N-((5-(3-chlorophenyl)-3-hydroxy-2-pyridinyl)carbonyl)- …
Matched Iupac: … 2-{[5-(3-chlorophenyl)-3-hydroxypyridin-2-yl]formamido}acetic acid …
Matched Iupac: … 2-{[5-(3-chlorophenyl)-3-hydroxypyridin-2-yl]formamido}acetic acid …
Influenza A virus A/South Australia/55/2014 live (attenuated) antigen
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Olaparib
Olaparib is a selective and potent inhibitor of poly (ADP-ribose) polymerase (PARP) enzymes, PARP1 and PARP2.[L41100, L40908, L43792] PARP inhibitors represent a novel class of anti-cancer therapy and they work by taking advantage of a defect in DNA repair in cancer cells with BRCA mutations and inducing cell death. Olaparib...
Approved
Matched Synonyms: … 4-(3-{[4-(cyclopropylcarbonyl)piperazin-1-yl]carbonyl}-4-fluorobenzyl)phthalazin-1(2H)-one …
Matched Iupac: … 4-{[3-(4-cyclopropanecarbonylpiperazine-1-carbonyl)-4-fluorophenyl]methyl}-1,2-dihydrophthalazin-1-one …
Matched Iupac: … 4-{[3-(4-cyclopropanecarbonylpiperazine-1-carbonyl)-4-fluorophenyl]methyl}-1,2-dihydrophthalazin-1-one …
Sulfamerazine
A sulfanilamide that is used as an antibacterial agent.
Approved
Vet approved
Matched Synonyms: … 2-(4-Aminobenzenesulfonamido)-4-methylpyrimidine ... 4-Amino-N-(4-methyl-2-pyrimidinyl)-benzenesulfonamide ... 2-Sulfa-4-methylpyrimidine …
Matched Iupac: … 4-amino-N-(4-methylpyrimidin-2-yl)benzene-1-sulfonamide …
Matched Iupac: … 4-amino-N-(4-methylpyrimidin-2-yl)benzene-1-sulfonamide …
Tegafur
Tegafur (INN, BAN, USAN) is a prodrug of DB00544 (5-FU), an antineoplastic agent used as the treatment of various cancers such as advanced gastric and colorectal cancers. It is a pyrimidine analogue used in combination therapies as an active chemotherapeutic agent in conjunction with DB09257 and DB03209, or along with...
Approved
Investigational
Matched Synonyms: … 1-(2-Tetrahydrofuryl)-5-fluorouracil …
Matched Iupac: … 5-fluoro-1-(oxolan-2-yl)-1,2,3,4-tetrahydropyrimidine-2,4-dione …
Matched Description: … high concentrations of 5-FU at a lower dose of tegafur [L933]. ... Tegafur (INN, BAN, USAN) is a prodrug of [DB00544] (5-FU), an antineoplastic agent used as the treatment ... Tegafur is usually given in combination with other drugs that enhance the bioavailability of the 5-FU …
Matched Iupac: … 5-fluoro-1-(oxolan-2-yl)-1,2,3,4-tetrahydropyrimidine-2,4-dione …
Matched Description: … high concentrations of 5-FU at a lower dose of tegafur [L933]. ... Tegafur (INN, BAN, USAN) is a prodrug of [DB00544] (5-FU), an antineoplastic agent used as the treatment ... Tegafur is usually given in combination with other drugs that enhance the bioavailability of the 5-FU …
Sumatriptan
Sumatriptan is a serotonin receptor agonist commonly used to treat migraines and sometimes cluster headaches.[L6793,L6796,L6799,L6805,L6808,L6811] Sumatriptan is the first of the triptans and was made available in Europe in 1991 to treat migraines. Sumatriptan was granted FDA approval on 28 December 1992.
Approved
Investigational
Matched Synonyms: … (3-[2-(dimethylamino)ethyl]-1H-indol-5-yl)-N-methylmethanesulfonamide ... 3-[2-(dimethylamino)ethyl]-N-methylindole-5-methanesulfonamide ... 3-(2-(dimethylamino)ethyl)-N-methyl-1H-indole-5-methanesulfonamide …
Matched Iupac: … 1-{3-[2-(dimethylamino)ethyl]-1H-indol-5-yl}-N-methylmethanesulfonamide …
Matched Salts cas: … 103628-48-4 …
Matched Categories: … Serotonin 5-HT1 Receptor Agonists ... Selective Serotonin 5-HT1 Receptor Agonists …
Matched Products: … SUTRIP 100 MG TABLET, 4 ADET …
Matched Iupac: … 1-{3-[2-(dimethylamino)ethyl]-1H-indol-5-yl}-N-methylmethanesulfonamide …
Matched Salts cas: … 103628-48-4 …
Matched Categories: … Serotonin 5-HT1 Receptor Agonists ... Selective Serotonin 5-HT1 Receptor Agonists …
Matched Products: … SUTRIP 100 MG TABLET, 4 ADET …
Letermovir
Letermovir recieved approval from the FDA on November 8th, 2017 for use in prophylaxis of cytomegalovirus (CMV) infection in allogeneic hematopoietic stem cell transplant patients. It is the first of a new class of CMV anti-infectives called DNA terminase complex inhibitors. Letermovir has recieved both priority and orphan drug status...
Approved
Investigational
Matched Iupac: … 2-[(4S)-8-fluoro-3-[2-methoxy-5-(trifluoromethyl)phenyl]-2-[4-(3-methoxyphenyl)piperazin-1-yl]-3,4-dihydroquinazolin ... -4-yl]acetic acid …
Displaying drugs 1426 - 1450 of 6848 in total