Displaying drugs 1426 - 1450 of 1936 in total
Tovinontrine
Tovinontrine is an orally administered, highly selective phosphodiesterase 9 (PDE9) small molecule inhibitor. Tovinontrine is under investigation in clinical trial NCT04474314 (A Study of IMR-687 in Subjects With Sickle Cell Disease).
Investigational
Matched Synonyms: … 6-((3S,4S)-4-METHYL-1-(2-PYRIMIDINYLMETHYL)-3-PYRROLIDINYL)-3-(TETRAHYDRO-2H-PYRAN-4-YL)IMIDAZO(1,5-A) ... 6-[(3S,4S)-4-methyl-1-(pyrimidin-2-ylmethyl)pyrrolidin-3-yl]-3- tetrahydropyran-4-yl-7H-imidazo[1,5-a] ... 6-[(3S,4S-4-methyl-1-(pyrimidin-2-ylmethyl)pyrrolidin-3-yl]-3-tetrahydropyran-4-yl-7H-imadazo[1,5-a]pyrazin …
Matched Iupac: … 6-[(3S,4S)-4-methyl-1-[(pyrimidin-2-yl)methyl]pyrrolidin-3-yl]-3-(oxan-4-yl)-7H,8H-imidazo[1,5-a]pyrazin …
Matched Description: … Tovinontrine is an orally administered, highly selective phosphodiesterase 9 (PDE9) small molecule inhibitor ... Tovinontrine is under investigation in clinical trial NCT04474314 (A Study of IMR-687 in Subjects With …
Matched Iupac: … 6-[(3S,4S)-4-methyl-1-[(pyrimidin-2-yl)methyl]pyrrolidin-3-yl]-3-(oxan-4-yl)-7H,8H-imidazo[1,5-a]pyrazin …
Matched Description: … Tovinontrine is an orally administered, highly selective phosphodiesterase 9 (PDE9) small molecule inhibitor ... Tovinontrine is under investigation in clinical trial NCT04474314 (A Study of IMR-687 in Subjects With …
Decyl(dimethyl)phosphine oxide
Experimental
Matched Name: … Decyl(dimethyl)phosphine oxide …
Matched Categories: … Phosphorus Compounds …
Matched Categories: … Phosphorus Compounds …
Cyclophosphamide
Precursor of an alkylating nitrogen mustard antineoplastic and immunosuppressive agent that must be activated in the liver to form the active aldophosphamide. It has been used in the treatment of lymphoma and leukemia. Its side effect, alopecia, has been used for defleecing sheep. Cyclophosphamide may also cause sterility, birth defects,...
Approved
Investigational
Matched Synonyms: … Bis(2-chloroethyl)phosphoramide cyclic propanolamide ester …
Matched Description: … Precursor of an alkylating nitrogen mustard antineoplastic and immunosuppressive agent that must be activated ... It has been used in the treatment of lymphoma and leukemia. ... Cyclophosphamide may also cause sterility, birth defects, mutations, and cancer. …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Cytochrome P-450 CYP2A6 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2B6 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C18 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C8 Substrates with a Narrow Therapeutic Index …
Matched Products: … CICLOFOSFAMIDA 1 G POLVO PARA RECONSTITUIR A SOLUCION INYECTABLE ... CICLOFOSFAMIDA 200 MG POLVO PARA RECONSTITUIR A SOLUCIÓN INYECTABLE. …
Matched Description: … Precursor of an alkylating nitrogen mustard antineoplastic and immunosuppressive agent that must be activated ... It has been used in the treatment of lymphoma and leukemia. ... Cyclophosphamide may also cause sterility, birth defects, mutations, and cancer. …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Cytochrome P-450 CYP2A6 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2B6 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C18 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C8 Substrates with a Narrow Therapeutic Index …
Matched Products: … CICLOFOSFAMIDA 1 G POLVO PARA RECONSTITUIR A SOLUCION INYECTABLE ... CICLOFOSFAMIDA 200 MG POLVO PARA RECONSTITUIR A SOLUCIÓN INYECTABLE. …
Mixed Carbamic Phosphoric Acid Anhydride of 7,8-Diaminononanic Acid
Experimental
Matched Name: … Mixed Carbamic Phosphoric Acid Anhydride of 7,8-Diaminononanic Acid …
Crotamiton
Crotamiton is a scabicidal and antipruritic agent available as a cream or lotion for topical use only. It is a colorless to slightly yellowish oil, having a faint amine-like odor. It is miscible with alcohol and with methanol.
Approved
Matched Description: … Crotamiton is a scabicidal and antipruritic agent available as a cream or lotion for topical use only ... It is miscible with alcohol and with methanol. ... It is a colorless to slightly yellowish oil, having a faint amine-like odor. …
Matched Categories: … Scabicides and Pediculicides ... Hydrocarbons, Cyclic ... Compounds used in a research, industrial, or household setting …
Matched Products: … A-Bite Cream ... CROTAMITON LOCION AL 10 % …
Matched Categories: … Scabicides and Pediculicides ... Hydrocarbons, Cyclic ... Compounds used in a research, industrial, or household setting …
Matched Products: … A-Bite Cream ... CROTAMITON LOCION AL 10 % …
5-O-phosphono-alpha-D-ribofuranosyl diphosphate
The key substance in the biosynthesis of histidine, tryptophan, and purine and pyrimidine nucleotides.
Approved
Experimental
Investigational
Matched Synonyms: … α-D-ribofuranose 5-(dihydrogen phosphate) 1-(trihydrogen diphosphate) …
Matched Iupac: … [({[(2R,3R,4S,5R)-3,4-dihydroxy-5-[(phosphonooxy)methyl]oxolan-2-yl]oxy}(hydroxy)phosphoryl)oxy]phosphonic …
Matched Description: … The key substance in the biosynthesis of histidine, tryptophan, and purine and pyrimidine nucleotides …
Matched Categories: … Sugar Phosphates …
Matched Iupac: … [({[(2R,3R,4S,5R)-3,4-dihydroxy-5-[(phosphonooxy)methyl]oxolan-2-yl]oxy}(hydroxy)phosphoryl)oxy]phosphonic …
Matched Description: … The key substance in the biosynthesis of histidine, tryptophan, and purine and pyrimidine nucleotides …
Matched Categories: … Sugar Phosphates …
Midecamycin
Midecamycin is a naturally occurring 16-membered macrolide that fits under the category of acetoxy-substituted macrolide antibiotics. In this molecule, an acetoxy group is substituted on the position 9 of the 16-member ring and on position 4 of the terminal sugar. Until 2017, midecamycin was still under the list of approved...
Experimental
Matched Synonyms: … Espinomycin A ... Medemycin A1 ... Medecamycin A1 …
Matched Description: … In this molecule, an acetoxy group is substituted on the position 9 of the 16-member ring and on position ... Midecamycin is a naturally occurring 16-membered macrolide[A33072] that fits under the category of acetoxy-substituted …
Matched Categories: … Macrolides, Lincosamides and Streptogramins …
Matched Description: … In this molecule, an acetoxy group is substituted on the position 9 of the 16-member ring and on position ... Midecamycin is a naturally occurring 16-membered macrolide[A33072] that fits under the category of acetoxy-substituted …
Matched Categories: … Macrolides, Lincosamides and Streptogramins …
PIK-75
PIK-75 is a preferential p110 alpha/gamma PI3K inhibitor.
Investigational
Matched Synonyms: … Benzenesulfonic acid, 2-methyl-5-nitro-, 2-((6-bromoimidazo(1,2-a)pyridin-3-yl)methylene)-1-methylhydrazide …
Matched Iupac: … N'-[(E)-{6-bromoimidazo[1,2-a]pyridin-3-yl}methylidene]-N,2-dimethyl-5-nitrobenzene-1-sulfonohydrazide …
Matched Description: … PIK-75 is a preferential p110 alpha/gamma PI3K inhibitor.[A253097] …
Matched Iupac: … N'-[(E)-{6-bromoimidazo[1,2-a]pyridin-3-yl}methylidene]-N,2-dimethyl-5-nitrobenzene-1-sulfonohydrazide …
Matched Description: … PIK-75 is a preferential p110 alpha/gamma PI3K inhibitor.[A253097] …
GYM329
GYM329 is a recombinant humanized IgG1-based monoclonal antibody which binds to human latent myostatin in a pH-dependent manner
Investigational
Matched Synonyms: … recombinant humanized IgG1-based monoclonal antibody which binds to human latent myostatin in a pH dependent …
Matched Description: … in a pH-dependent manner ... GYM329 is a recombinant humanized IgG1-based monoclonal antibody which binds to human latent myostatin …
Matched Description: … in a pH-dependent manner ... GYM329 is a recombinant humanized IgG1-based monoclonal antibody which binds to human latent myostatin …
Epinastine
Epinastine is used for the prevention of itching associated with allergic conjunctivitis. It has a multi-action effect that inhibits the allergic response in 3 ways: 1. stabilizes mast cells by preventing mast cell degranulation to control the allergic response, 2. prevents histamine binding to both the H1- and H2-receptors to...
Approved
Investigational
Matched Synonyms: … 3-amino-9,13b-dihydro-1H-dibenz(c,f)imidazo(1,5-a)azepine …
Matched Description: … H2-receptors to stop itching and provide lasting protection, and 3. prevents the release of proinflammatory ... cell degranulation to control the allergic response, 2. prevents histamine binding to both the H1- and ... It has a multi-action effect that inhibits the allergic response in 3 ways: 1. stabilizes mast cells …
Matched Categories: … Decongestants and Antiallergics …
Matched Description: … H2-receptors to stop itching and provide lasting protection, and 3. prevents the release of proinflammatory ... cell degranulation to control the allergic response, 2. prevents histamine binding to both the H1- and ... It has a multi-action effect that inhibits the allergic response in 3 ways: 1. stabilizes mast cells …
Matched Categories: … Decongestants and Antiallergics …
Etizolam
Etizolam is a thienodiazepine which is chemically related to benzodiazepine (BDZ) drug class; it differs from BDZs in having a benzene ring replaced with a thiophene ring. It is an agonist at GABA-A receptors and possesses amnesic, anxiolytic, anticonvulsant, hypnotic, sedative and skeletal muscle relaxant properties. Initially introduced in 1983...
Experimental
Matched Synonyms: … 4-(o-Chlorophenyl)-2-ethyl-9-methyl-6H-thieno(3,2-f)-s-triazolo(4,3-a)(1,4)diazepine …
Matched Description: … It is an agonist at GABA-A receptors and possesses amnesic, anxiolytic, anticonvulsant, hypnotic, sedative ... Initially introduced in 1983 in Japan as treatment for neurological conditions such as anxiety and sleep ... and skeletal muscle relaxant properties. …
Matched Categories: … Benzodiazepine hypnotics and sedatives ... Hypnotics and Sedatives ... Benzodiazepines and benzodiazepine derivatives …
Matched Description: … It is an agonist at GABA-A receptors and possesses amnesic, anxiolytic, anticonvulsant, hypnotic, sedative ... Initially introduced in 1983 in Japan as treatment for neurological conditions such as anxiety and sleep ... and skeletal muscle relaxant properties. …
Matched Categories: … Benzodiazepine hypnotics and sedatives ... Hypnotics and Sedatives ... Benzodiazepines and benzodiazepine derivatives …
Antineoplaston A10
Antineoplaston A10 has been used in trials studying the treatment of Sarcoma, Lymphoma, Lung Cancer, Liver Cancer, and Kidney Cancer, among others.
Investigational
Matched Synonyms: … Antineoplaston A 10 …
Matched Name: … Antineoplaston A10 …
Matched Description: … Liver Cancer, and Kidney Cancer, among others. ... Antineoplaston A10 has been used in trials studying the treatment of Sarcoma, Lymphoma, Lung Cancer, …
Matched Categories: … Hydrocarbons, Cyclic …
Matched Name: … Antineoplaston A10 …
Matched Description: … Liver Cancer, and Kidney Cancer, among others. ... Antineoplaston A10 has been used in trials studying the treatment of Sarcoma, Lymphoma, Lung Cancer, …
Matched Categories: … Hydrocarbons, Cyclic …
Zalunfiban
Investigational
Matched Synonyms: … 2-amino-n-(4-(5-oxo-7-(piperazin-1-yl)-5h-(1,3,4)thiadiazolo(3,2-a)pyrimidin-2-yl)pyridin-2-yl)acetamide ... Acetamide, 2-amino-n-(5-(5-oxo-7-(1-piperazinyl)-5h-1,3,4-thiadiazolo(3,2- a)pyrimidin-2-yl)-3-pyridinyl …
Lipoic acid
A vitamin-like antioxidant.
Approved
Investigational
Nutraceutical
Matched Description: … A vitamin-like antioxidant. …
Matched Mixtures name: … Protect Cardio AF ... SURBEX Natopherol ALA PLUS ... ActiveLife ALA Plus Capsule …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism ... Various Alimentary Tract and Metabolism Products ... Coenzymes ... Compounds used in a research, industrial, or household setting …
Matched Products: … A-LIPOR® ... ALA-SR 300mg Tablet ... ALPHA LIPON AL 600 …
Matched Mixtures name: … Protect Cardio AF ... SURBEX Natopherol ALA PLUS ... ActiveLife ALA Plus Capsule …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism ... Various Alimentary Tract and Metabolism Products ... Coenzymes ... Compounds used in a research, industrial, or household setting …
Matched Products: … A-LIPOR® ... ALA-SR 300mg Tablet ... ALPHA LIPON AL 600 …
Beclomethasone dipropionate
Beclomethasone dipropionate is a second-generation synthetic corticosteroid and diester of beclomethasone, which is structurally similar to dexamethasone. It is a prodrug of an active metabolite beclomethasone 17-monopropionate (17-BMP) which acts on the glucocorticoid receptor to mediates its therapeutic action. Beclomethasone dipropionate itself posesses weak glucocorticoid receptor binding affinity and is...
Approved
Investigational
Matched International brands: … Clenil-A …
Matched Iupac: … 2,9a,11a-trimethyl-7-oxo-1-(propanoyloxy)-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Matched Description: … later in a dry powder inhaler and an aqueous nasal spray. ... Beclomethasone dipropionate is a second-generation[A179842] synthetic corticosteroid and diester of beclomethasone ... [A179839] Formulations for oral inhalation, intranasal, and topical use are available for beclomethasone …
Matched Mixtures name: … Ibicar S (Salbutamol 100 mcg/actuation and Beclometasone 50 mcg/actuation) Pressurised Inhalation …
Matched Categories: … Alimentary Tract and Metabolism ... formoterol and beclometasone ... salbutamol and beclometasone ... beclometasone and antibiotics ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … CYCLOCAPS BECLOME 100+CYCL ... CYCLOCAPS BECLOME 200+CYCL ... CYCLOCAPS BECLOME 400+CYCL …
Matched Iupac: … 2,9a,11a-trimethyl-7-oxo-1-(propanoyloxy)-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Matched Description: … later in a dry powder inhaler and an aqueous nasal spray. ... Beclomethasone dipropionate is a second-generation[A179842] synthetic corticosteroid and diester of beclomethasone ... [A179839] Formulations for oral inhalation, intranasal, and topical use are available for beclomethasone …
Matched Mixtures name: … Ibicar S (Salbutamol 100 mcg/actuation and Beclometasone 50 mcg/actuation) Pressurised Inhalation …
Matched Categories: … Alimentary Tract and Metabolism ... formoterol and beclometasone ... salbutamol and beclometasone ... beclometasone and antibiotics ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … CYCLOCAPS BECLOME 100+CYCL ... CYCLOCAPS BECLOME 200+CYCL ... CYCLOCAPS BECLOME 400+CYCL …
Flavin-N7 protonated-adenine dinucleotide
Experimental
Matched Name: … Flavin-N7 protonated-adenine dinucleotide …
Matched Iupac: … )oxy](hydroxy)phosphoryl}oxy)methyl]-3,4-dihydroxyoxolan-2-yl]-9H-purin-6-aminium ... -5-{7,8-dimethyl-2,4-dioxo-2H,3H,4H,10H-benzo[g]pteridin-10-yl}-2,3,4-trihydroxypentyl]oxy}(hydroxy)phosphoryl …
Matched Iupac: … )oxy](hydroxy)phosphoryl}oxy)methyl]-3,4-dihydroxyoxolan-2-yl]-9H-purin-6-aminium ... -5-{7,8-dimethyl-2,4-dioxo-2H,3H,4H,10H-benzo[g]pteridin-10-yl}-2,3,4-trihydroxypentyl]oxy}(hydroxy)phosphoryl …
3-Aminomethyl-Pyridinium-Adenine-Dinucleotide
Experimental
Matched Name: … 3-Aminomethyl-Pyridinium-Adenine-Dinucleotide …
Matched Iupac: … ({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphonato}oxy)(hydroxy)phosphoryl …
Matched Iupac: … ({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphonato}oxy)(hydroxy)phosphoryl …
Procinonide
Approved
Investigational
Matched Synonyms: … .,17,21-tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal with acetone, 21-propionate …
Fosciclopirox
Investigational
Matched Synonyms: … ((6-cyclohexyl-4-methyl-2-oxopyridin-1(2h)-yl)oxy)methyl dihydrogen phosphate …
5-Bromo-2'-deoxyuridine 5'-(dihydrogen phosphate)
Experimental
Matched Name: … 5-Bromo-2'-deoxyuridine 5'-(dihydrogen phosphate) …
Erythropoietin
Erythropoietin (EPO) is a growth factor produced in the kidneys that stimulates the production of red blood cells. It works by promoting the division and differentiation of committed erythroid progenitors in the bone marrow [FDA Label]. Epoetin alfa (Epoge) was developed by Amgen Inc. in 1983 as the first rhEPO...
Approved
Matched Description: … The biosimilar is approved by the FDA and EMA as a safe, effective and affordable biological product ... Erythropoietin (EPO) is a growth factor produced in the kidneys that stimulates the production of red ... and displays equivalent clinical efficacy, potency, and purity to the reference product [A7504]. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Intercellular Signaling Peptides and Proteins …
Matched Products: … EXETIN-A ... EPO STADA 2000IU/0.6ml Solution for Injection in a Pre-filled Syringe ... EPO STADA 4000IU/0.4ml Solution for Injection in a Pre-filled Syringe …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Intercellular Signaling Peptides and Proteins …
Matched Products: … EXETIN-A ... EPO STADA 2000IU/0.6ml Solution for Injection in a Pre-filled Syringe ... EPO STADA 4000IU/0.4ml Solution for Injection in a Pre-filled Syringe …
JQ1
First-in-class potent and selective inhibitor of the BRD4 signaling pathway.
Investigational
Matched Synonyms: … (s)-(+)-tert-butyl 2-(4-(4-chlorophenyl)-2,3,9-trimethyl-6h-thieno(3,2-f)(1,2,4)triazolo(4,3-a)(1,4)diazepin ... 6h-thieno(3,2-f)(1,2,4)triazolo(4,3-a)(1,4)diazepine-6-acetic acid, 4-(4-chlorophenyl)-2,3,9-trimethyl ... Tert-butyl 2-((6s)-4-(4-chlorophenyl)-2,3,9-trimethyl-6h-thieno(3,2-f)(1,2,4)triazolo(4,3-a)(1,4)diazepin …
Matched Description: … First-in-class potent and selective inhibitor of the BRD4 signaling pathway.[A252967] …
Matched Description: … First-in-class potent and selective inhibitor of the BRD4 signaling pathway.[A252967] …
(1R,2R,3S,4R,6S)-3,4,6-Trihydroxy-5-{[(S)-hydroxy(3-hydroxy-2-oxopropoxy)phosphoryl]oxy}-1,2-cyclohexanediyl bis[dihydrogen (phosphate)]
Experimental
Matched Name: … bis[dihydrogen (phosphate)] ... (1R,2R,3S,4R,6S)-3,4,6-Trihydroxy-5-{[(S)-hydroxy(3-hydroxy-2-oxopropoxy)phosphoryl]oxy}-1,2-cyclohexanediyl …
Matched Iupac: … {[(1R,2S,3R,5S,6R)-2,3,5-trihydroxy-4-{[hydroxy(3-hydroxy-2-oxopropoxy)phosphoryl]oxy}-6-(phosphonooxy …
Matched Iupac: … {[(1R,2S,3R,5S,6R)-2,3,5-trihydroxy-4-{[hydroxy(3-hydroxy-2-oxopropoxy)phosphoryl]oxy}-6-(phosphonooxy …
Displaying drugs 1426 - 1450 of 1936 in total