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Displaying drugs 1451 - 1475 of 1667 in total

Dexrazoxane

An antimitotic agent with immunosuppressive properties. Dexrazoxane, the (+)-enantiomorph of razoxane, provides cardioprotection against anthracycline toxicity. It appears to inhibit formation of a toxic iron-anthracycline complex. [PubChem] The Food and Drug Administration has designated dexrazoxane as an orphan drug for use in the prevention or reduction in the incidence and...
Approved
Withdrawn
Matched Description: … [PubChem] The Food and Drug Administration has designated dexrazoxane as an orphan drug for use in the ... prevention or reduction in the incidence and severity of anthracycline-induced cardiomyopathy. …
Matched Categories: … Detoxifying Agents for Antineoplastic Treatment …
Matched Products: … Dexrazoxane for Injection …

Lutropin alfa

Lutropin alfa is a recombinant human luteinizing hormone produced in yeast with 2 subunits, alpha = 92 residues, beta = 121 residues. It is a heterodimeric glycoprotein made up of monomeric units. Lutropin alfa was the first and only recombinant human form of luteinizing hormone (LH) developed for use in...
Approved
Matched Description: … Lutropin alfa was the first and only recombinant human form of luteinizing hormone (LH) developed for ... biological activity of endogenous LH; an acute rise of LH, or LH surge, in females triggers ovulation and …
Matched Mixtures name: … Pergoveris 150IU/75IU powder and solvent for solution for injection ... Pergoveris Powder and Solvent for Solution for Injection 150iu/75iu …
Matched Categories: … Genito Urinary System and Sex Hormones ... Gonadotropins and Antigonadotropins ... Sex Hormones and Modulators of the Genital System …
Matched Products: … LUVERIS FOR INJECTION 75 iu/vial (Revised formula) …

Rabies virus inactivated antigen, A

Rabies virus inactivated antigen, A is an inactivated virus vacine for the intramuscular injection. It is an active immunization against rabies that can be administered pre- or post-exposure to the rabies virus.
Approved
Investigational
Matched Description: … Rabies virus inactivated antigen, A is an inactivated virus vacine for the intramuscular injection. …
Matched Categories: … Immune Sera and Immunoglobulins ... Antiinfectives for Systemic Use …
Matched Products: … Rabipur Lyophilised Powder for Injection …

Furosemide

Furosemide is a potent loop diuretic that acts on the kidneys to ultimately increase water loss from the body. It is an anthranilic acid derivative. Furosemide is used for edema secondary to various clinical conditions, such as congestive heart failure exacerbation, liver failure, renal failure, and high blood pressure. It...
Approved
Vet approved
Matched Description: … In addition to oral formulations, the solution for intravenous and intramuscular administration is also ... Furosemide has a fast onset and short duration of action and has been used safely and effectively in ... both pediatric and adult patients. …
Matched Mixtures name: … SPIRO COMP FORTE RAT100/20 ... SPIRO COMP FORTE RAT100/20 ... SPIRO COMP FORTE RAT100/20 …
Matched Salts name: … Furosemide sodium …
Matched Categories: … Sodium Potassium Chloride Symporter Inhibitors ... furosemide and potassium ... furosemide and potassium-sparing agents ... High-Ceiling Diuretics and Potassium-Sparing Agents ... Antihypertensive Agents Indicated for Hypertension …
Matched Products: … DIRINE FORTE (INJECTION) ... FUROSEMIDE-BAXTER SOLUTION FOR INJECTION 50 MG/5 ML ... FUROSEMIDE-BAXTER SOLUTION FOR INJECTION 20 MG/2 ML …

Carbocisteine

Dyspnea and cough are common symptoms of chronic obstructive pulmonary disease (COPD) and other respiratory conditions characterized by increased mucus production. Individuals with COPD have a greater risk of pulmonary infection due to the growth and accumulation of viruses and bacteria in thick bronchial mucus. Carbocisteine is a mucolytic drug...
Approved
Investigational
Matched Description: … [L32383] Several licenses for this drug were withdrawn following serious and fatal paradoxical effects ... [A230993] Carbocisteine is currently not FDA or Health Canada approved, but is approved for use in Asia ... Dyspnea and cough are common symptoms of chronic obstructive pulmonary disease (COPD)[A231169] and other …
Matched Mixtures name: … AXIM TOSTHERAPY FORTE® …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Cough and Cold Preparations …
Matched Products: … MUKO-S FORT 375 MG TABLET , 20 ADET ... MUKOTIK FORT 375 MG TABLET, 20 ADET ... MUKOTIK FORT 375 MG TABLET, 50 ADET …

Melphalan

Melphalan is a nitrogen mustard or bischloroethylamine type alkylating agent. It was first synthesized in the early 1950s by substituting L-phenylalanine for the methyl group on nitrogen mustard.[A261150, A261155] Melphalan is used in the treatment of multiple myeloma and ovarian carcinoma. It is also used for high-conditioning before hematopoietic stem...
Approved
Matched Description: … [A261150, A261155] Melphalan is used in the treatment of multiple myeloma and ovarian carcinoma. ... [L40928] It is also used for high-conditioning before hematopoietic stem cell transplant. ... [L40928] It was first synthesized in the early 1950s by substituting L-phenylalanine for the methyl group …
Matched Mixtures name: … Melphalan for Injection ... Melphalan for Injection …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Products: … Melphalan for Injection ... ALKERAN FOR INJECTION 50 mg/vial …

Etoposide

A semisynthetic derivative of podophyllotoxin that exhibits antitumor activity. Etoposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA. This complex induces breaks in double stranded DNA and prevents repair by topoisomerase II binding. Accumulated breaks in DNA prevent entry into the mitotic phase of cell division,...
Approved
Matched Description: … Etoposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA. ... Etoposide acts primarily in the G2 and S phases of the cell cycle. ... This complex induces breaks in double stranded DNA and prevents repair by topoisomerase II binding. …
Matched Salts name: … Etoposide phosphate …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … MYLAN ETOPOSIDE CONCENTRATE FOR SOLUTION FOR INJECTION 20MG/ML ... ETOPOSIDE CONCENTRATE FOR SOLUTION FOR INJECTION 20mg/ml …

Epirubicin

An anthracycline which is the 4'-epi-isomer of doxorubicin. The compound exerts its antitumor effects by interference with the synthesis and function of DNA.
Approved
Matched Description: … The compound exerts its antitumor effects by interference with the synthesis and function of DNA. …
Matched Categories: … Anthracyclines and Related Substances ... Antineoplastic and Immunomodulating Agents ... Cytotoxic Antibiotics and Related Substances …
Matched Products: … EPIROL Epirubicin Hydrochloride Powder for Solution for Injection 10mg ... EPIROL Epirubicin Hydrochloride Powder for Solution for Injection 50mg ... Epirubicin for Injection …

Hepatitis B Vaccine (Recombinant)

Hepatitis B Vaccine is an ingredient in the EMA-withdrawn product Quintanrix. It is marketed in Canada as Engerix B. It is also a part of Twinrix (Hep A/Hep B vaccine) available also in Canada. The hepatitis B virus induces a severe form of viral hepatitis. Other causative agents are hepatitis...
Approved
Withdrawn
Matched Description: … There is no specific treatment for hepatitis. ... The hepatitis B virus induces a severe form of viral hepatitis. ... Other causative agents are hepatitis A virus, and the non-A, non-B hepatitis viruses. …
Matched Mixtures name: … Hexaxim Suspension for Injection …
Matched Categories: … Antiinfectives for Systemic Use ... Amino Acids, Peptides, and Proteins ... Bacterial and viral vaccines, combined ... haemophilus influenzae B and hepatitis B …
Matched Products: … Engerix-B 20 Adult Dose Suspension for Injection ... Engerix-B 10 Junior Dose Suspension for Injection ... ENGERIX-B SUSPENSION FOR INJECTION IN PREFILLED SYRINGE 20MCG/ML …

Hydroxycitronellal

Hydroxycitronellal is a synthetic fragrance that is widely used in many cosmetics and hygiene products such as deodorants, soaps, antiseptics, and other household items. It has the smell of lilac, lily, and lily of the valley . Hydroxycitronellal has also been shown to be a dermatologic irritant and allergen, and...
Approved
Experimental
Matched Synonyms: … Citronellal hydrate …
Matched Description: … Hydroxycitronellal has also been shown to be a dermatologic irritant and allergen, and as a result commercially ... such as deodorants, soaps, antiseptics, and other household items. ... Hydroxycitronellal is a synthetic fragrance that is widely used in many cosmetics and hygiene products …

Ioflupane I-123

Ioflupane (I-123) is a radiopharmaceutical used to image dopamine neurons and diagnose Parkinsonian syndromes.
Approved
Matched Description: … Ioflupane (I-123) is a radiopharmaceutical used to image dopamine neurons and diagnose Parkinsonian syndromes …
Matched Products: … DATSCAN SOLUTION FOR INJECTION 74 MBQ/ML …

3-FORMYL-2-HYDROXY-5-METHYL-HEXANOIC ACID HYDROXYAMIDE

Experimental
Matched Name: … 3-FORMYL-2-HYDROXY-5-METHYL-HEXANOIC ACID HYDROXYAMIDE …
Matched Iupac: … (2S,3R)-3-formyl-N,2-dihydroxy-5-methylhexanamide …

Lenograstim

Lenograstim is a recombinant granulocyte colony-stimulating factor used as an immunostimulating agent.
Approved
Investigational
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins …
Matched Products: … GRANOCYTE 34 FOR INJECTION 263 mcg/ml …

Temsirolimus

Temsirolimus is a derivative of sirolimus used in the treatment of renal cell carcinoma (RCC). It was developed by Wyeth Pharmaceuticals under the trade name Torisel. Temsirolimus was approved by the FDA in late May 2007 as well as the European Medicines Agency (EMEA) on November 2007.
Approved
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Sirolimus and Prodrugs …
Matched Products: … Torisel Concentrate for Injection 25mg/mL …

Ganirelix

Ganirelix is a synthetic decapeptide and a competitive gonadotropin-releasing hormone (GnRH) antagonist. Derived from endogenous GnRH, ganirelix has amino acid substitutions. Ganirelix is indicated for controlled ovarian hyperstimulation in assisted reproduction techniques. The first case of pregnancy achieved after the use of ganirelix in an assisted reproduction program was reported...
Approved
Matched Description: … Ganirelix is a synthetic decapeptide and a competitive gonadotropin-releasing hormone (GnRH) antagonist ... Ganirelix is indicated for controlled ovarian hyperstimulation in assisted reproduction techniques. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Pituitary and Hypothalamic Hormones and Analogues ... Sex Hormones and Insulins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … ORGALUTRAN 0.25MG/0.5ML (SOLUTION FOR INJECTION) ... ORGALUTRAN SOLUTION FOR INJECTION 0.25 mg/0.5 ml …

Polymyxin B

Polymyxin B was discovered in the 1940s . They are basic polypeptides of about eight amino acids and have cationic detergent action on cell membranes . Polymyxin B is used for infections with gram-negative organisms, but may be neurotoxic and nephrotoxic[A176426,FDA Label]. All gram-positive bacteria, fungi, and the gram-negative cocci,...
Approved
Vet approved
Matched Description: … Polymyxin B is used for infections with gram-negative organisms, but may be neurotoxic and nephrotoxic ... It is appropriate for treatment of infections of the urinary tract, meninges, and blood stream, caused ... Polymyxin B has a narrow therapeutic index and so its use is limited and unlikely to be used first line …
Matched Mixtures name: … DEXAMETASONA SODIO FOSFATO+ POLIMIXINA B SULFATO + NEOMICINA SULFATOSOLUCION OFTALMICA ... NEOMICINA SULFATO 3.5 MG + DEXAMATASONA SODIO FOSFATO 1.3MG + POLIMIXINA B SULFATO 6.600U.I / ML SOLUCION ... DEXAMETASONA SODIO FOSFATO 1.3 MG/ML. SOLUCIÓN OFTÁLMICA ESTÉRIL. …
Matched Salts name: … Polymyxin B sulfate …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... Ophthalmological and Otological Preparations ... Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … Polymyxin B for Injection USP ... POLY-MxB for Injection U.S.P. 500,000 Units (Lyophilized) …

Benzoic acid

A fungistatic compound that is widely used as a food preservative. It is conjugated to GLYCINE in the liver and excreted as hippuric acid. As the sodium salt form, sodium benzoate is used as a treatment for urea cycle disorders due to its ability to bind amino acids. This leads...
Approved
Investigational
Matched Description: … As the sodium salt form, sodium benzoate is used as a treatment for urea cycle disorders due to its ability ... It is conjugated to GLYCINE in the liver and excreted as hippuric acid. ... This leads to excretion of these amino acids and a decrease in ammonia levels. …
Matched Mixtures name: … Sodium Phenylacetate and Sodium Benzoate ... Sodium Phenylacetate and Sodium Benzoate ... REXOM WINACOL SYRUP FOR CHILDREN …
Matched Salts name: … Calcium benzoate ... Sodium benzoate …
Matched Categories: … sodium benzoate and sodium phenylacetate ... caffeine and sodium benzoate ... Tests for Gastric Secretion ... Alimentary Tract and Metabolism ... sodium benzoate …
Matched Products: … S Panax Mist for Refill …

Selenium

Selenium is a trace metal in the human body particularly important as a component of glutathione peroxidase, an important enzyme in the prevention of cellular damage by free radicals and reactive oxygen species [FDA Label]
Approved
Investigational
Vet approved
Matched Description: … of glutathione peroxidase, an important enzyme in the prevention of cellular damage by free radicals and …
Matched Mixtures name: … Multivitamins and Minerals for Men ... Multivitamins and Minerals for Women ... Luna Vitamin and Mineral Bar for Women …
Matched Categories: … Alimentary Tract and Metabolism ... Diet, Food, and Nutrition …
Matched Products: … selenase ® 100 micrograms, solution for injection (50 micrograms/ml) ... selenase 500 micrograms, solution for injection (50 micrograms/ml) …

Calfactant

Calfactant is a sterile, non-pyrogenic lung surfactant intended for intratracheal instillation. It is an off-white suspension of an extract of natural surfactant from calf lungs suspended in 0.9% saline. Each milliliter of calfactant contains 35mg of phospholipids (including 26 mg phosphatidylcholine of which 16 mg is disaturated phosphatidylcholine) and 0.65mg...
Approved
Matched Description: … 0.65mg of proteins including surfactant-associated proteins B and C. ... Calfactant is approved for use in the United States of America. ... phospholipids (including 26 mg phosphatidylcholine of which 16 mg is disaturated phosphatidylcholine) and …
Matched Products: … BLES (bovine lipid extract surfactant) 27 mg/ml Suspension for Intratracheal Instillation …

4,6-Dideoxy-4-{[(1S,5R,6S)-3-formyl-5,6-dihydroxy-4-oxo-2-cyclohexen-1-yl]amino}-α-D-xylo-hex-5-enopyranose

Experimental
Matched Synonyms: … 4,6-Dideoxy-4-{[(1s,5r,6s)-3-formyl-5,6-dihydroxy-4-oxocyclohex-2-en-1-yl]amino}-alpha-d-xylo-hex-5-enopyranose …
Matched Name: … 4,6-Dideoxy-4-{[(1S,5R,6S)-3-formyl-5,6-dihydroxy-4-oxo-2-cyclohexen-1-yl]amino}-α-D-xylo-hex-5-enopyranose …

Cetuximab

Cetuximab is a recombinant chimeric human/mouse IgG1 monoclonal antibody that competitively binds to epidermal growth factor receptor (EGFR) and competitively inhibits the binding of epidermal growth factor (EGF). EGFR is a member of the ErbB family of receptor tyrosine kinases found in both normal and tumour cells; it is responsible...
Approved
Matched Description: … cells; it is responsible for regulating epithelial tissue development and homeostasis. ... [A227963] Approved by the FDA in February 2004 under the brand name ERBITUX, cetuximab is used for ... the treatment of head and neck cancer and metastatic, KRAS wild-type colorectal cancer, and metastatic …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Matched Products: … ERBITUX 5MG/ML SOLUTION FOR INFUSION …

Coenzyme M

Coenzyme M (commonly known by its salt form, Mesna) is a synthetic sulfhydryl (thiol) compound and is used for prophylaxis of Ifosfamide and cyclophosphamide induced hemorrhagic cystitis.
Approved
Investigational
Matched Description: … Coenzyme M (commonly known by its salt form, Mesna) is a synthetic sulfhydryl (thiol) compound and is ... used for prophylaxis of Ifosfamide and cyclophosphamide induced hemorrhagic cystitis. …
Matched Mixtures name: … IFEX and MESNEX ... IFEX and MESNEX ... IFEX and MESNEX …
Matched Categories: … Cough and Cold Preparations ... Detoxifying Agents for Antineoplastic Treatment …
Matched Products: … Mesna for Injection ... CONCENTRATE SOLUTION FOR INJECTION 400MG/4ML …

Indacaterol

Indacaterol is a novel, ultra-long-acting, rapid onset β(2)-adrenoceptor agonist developed for Novartis for the once-daily management of asthma and chronic obstructive pulmonary disease. It was approved by the European Medicines Agency (EMA) on 30 November 2009 and by the FDA on 1 July 2011. It is marketed in Europe as...
Approved
Matched Description: … for the once-daily management of asthma and chronic obstructive pulmonary disease. ... It is marketed in Europe as Onbrez and in America as Arcapta Neohaler. ... It was approved by the European Medicines Agency (EMA) on 30 November 2009 and by the FDA on 1 July 2011 …
Matched Categories: … Drugs for Obstructive Airway Diseases ... indacaterol and mometasone ... indacaterol and glycopyrronium bromide ... indacaterol, glycopyrronium bromide and mometasone …
Matched Products: … Onbrez Breezhaler Powder for inhalation Hard Capsule 300 mcg ... Onbrez Breezhaler Powder for Inhalation Hard Capsule 150 mcg …

Exametazime

Exametazime is a diagnostic radiopharmaceutical agent commonly used for the preparation of Tc99m Exametazime injection. It acts as a chelating agent for the radioisotope technetium-99m to form a cationic complex. It is used in the detection of altered regional cerebral perfusion and for the radiolabeling of autologous leukocytes.
Approved
Matched Description: … It is used in the detection of altered regional cerebral perfusion and for the radiolabeling of autologous ... It acts as a chelating agent for the radioisotope technetium-99m to form a cationic complex. ... Exametazime is a diagnostic radiopharmaceutical agent commonly used for the preparation of Tc99m Exametazime …
Matched Products: … CERETEC FOR INJECTION 0.5 mg/vial …

Betiatide

Approved
Experimental
Matched Products: … Kit for the Preparation of Technetium Tc99m Mertiatide …
Displaying drugs 1451 - 1475 of 1667 in total