This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Brand Names
Rabavert
Generic Name
Rabies virus inactivated antigen, A
DrugBank Accession Number
DB10283
Background

Rabies virus inactivated antigen, A is an inactivated virus vacine for the intramuscular injection. It is an active immunization against rabies that can be administered pre- or post-exposure to the rabies virus.

Type
Biotech
Groups
Approved, Investigational
Biologic Classification
Vaccines
Inactivated
Synonyms
  • Rabies virus strain flury lep antigen (propiolactone inactivated)
  • Rabies virus vaccine flury-lep strain

Pharmacology

Indication

Not Available

Pharmacology
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Associated Conditions
Associated Therapies
Contraindications & Blackbox Warnings
Contraindications
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
Adverseeffects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
DrugInteraction
AbataceptThe therapeutic efficacy of Rabies virus inactivated antigen, A can be decreased when used in combination with Abatacept.
AdalimumabThe therapeutic efficacy of Rabies virus inactivated antigen, A can be decreased when used in combination with Adalimumab.
AldesleukinThe therapeutic efficacy of Rabies virus inactivated antigen, A can be decreased when used in combination with Aldesleukin.
AlefaceptThe therapeutic efficacy of Rabies virus inactivated antigen, A can be decreased when used in combination with Alefacept.
AlemtuzumabThe therapeutic efficacy of Rabies virus inactivated antigen, A can be decreased when used in combination with Alemtuzumab.
AltretamineThe therapeutic efficacy of Rabies virus inactivated antigen, A can be decreased when used in combination with Altretamine.
AmsacrineThe therapeutic efficacy of Rabies virus inactivated antigen, A can be decreased when used in combination with Amsacrine.
AnakinraThe therapeutic efficacy of Rabies virus inactivated antigen, A can be decreased when used in combination with Anakinra.
Antilymphocyte immunoglobulin (horse)The therapeutic efficacy of Rabies virus inactivated antigen, A can be decreased when used in combination with Antilymphocyte immunoglobulin (horse).
Antithymocyte immunoglobulin (rabbit)The therapeutic efficacy of Rabies virus inactivated antigen, A can be decreased when used in combination with Antithymocyte immunoglobulin (rabbit).
Interactions
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Food Interactions
Not Available

Products

Products2
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Brand Name Prescription Products
NameDosageStrengthRouteLabellerMarketing StartMarketing EndRegionImage
RabAvertKit2.5 [iU]/1mLIntramuscularA-S Medication Solutions2016-12-19Not applicableUS flag
RabAvertKit2.5 [iU]/1mLIntramuscularBavarian Nordic A/S1997-11-11Not applicableUS flag
RabAvertKit2.5 [iU]/1mLIntramuscularGSK Vaccines GmbH2014-07-082020-03-31US flag
RabAvertKit2.5 [iU]/1mLIntramuscularGlaxoSmithKline Biologicals SA2016-12-192024-01-31US flag
RabAvertKit2.5 [iU]/1mLIntramuscularA-S Medication Solutions2014-07-082020-03-31US flag

Categories

ATC Codes
J06AA06 — Rabies serum
Drug Categories
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
FK894Q51YE
CAS number
Not Available

References

General References
Not Available
PubChem Substance
347910469
RxNav
830457

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
4Active Not RecruitingBasic ScienceRabies Human1
4CompletedBasic ScienceRabies2
4CompletedPreventionRabies1
4CompletedPreventionRabies Vaccine Allergy1
4CompletedTreatmentRabies1
4Unknown StatusHealth Services ResearchRabies1
4WithdrawnPreventionVirus Diseases1
3Active Not RecruitingPreventionCommunicable Diseases / Mononegavirales Infections / Rabies / Rhabdoviridae Infections / Virus Diseases / Virus Infection, RNA1
3CompletedPreventionAdverse Effect and Immunogenicity of Vaccine1
3CompletedPreventionEncephalitis, Japanese B / Meningococcal Disease / Meningococcal Meningitis / Rabies / Salmonella Typhi Infection / Yellow Fever1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
InjectionIntradermal; Intramuscular
KitIntramuscular2.5 [iU]/1mL
Injection, powder, lyophilized, for solutionIntramuscular≥ 2.5 IU
Injection, powder, lyophilized, for solutionIntramuscular
Injection, powder, for solutionIntramuscular2.5 iu/mL
Injection, powder, for solutionIntramuscular2.5 IU
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available

Drug created at November 30, 2015 21:24 / Updated at June 12, 2020 16:52