Displaying drugs 126 - 150 of 5058 in total
Streptococcus pneumoniae type 15b capsular polysaccharide antigen
Streptococcus pneumoniae type 15b capsular polysaccharide antigen is a vaccine that contains highly purified capsular polysaccharides from the invasive pneumococcal type 15b of Streptococcus pneumoniae. It is an active immunization for intramuscular or subcutaneous injection against pneumococcal disease such as pneumococcal pneumonia and pneumococcal bacteremia.
Approved
Investigational
Matched Name: … Streptococcus pneumoniae type 15b capsular polysaccharide antigen …
Matched Description: … Streptococcus pneumoniae type 15b capsular polysaccharide antigen is a vaccine that contains highly purified …
Matched Description: … Streptococcus pneumoniae type 15b capsular polysaccharide antigen is a vaccine that contains highly purified …
Bacillus calmette-guerin substrain connaught live antigen
Bacillus calmette-guerin substrain connaught live antigen is intravesically administered for the treatment and prophylaxis of carcinoma in situ (CIS) of the urinary bladder and for the prophylaxis of primary or recurrent stage Ta and/or T1 papillary tumors following transurethral resection (TUR). The solution contains live, attenuated strain of Mycobacterium bovis....
Approved
Investigational
Matched Name: … Bacillus calmette-guerin substrain connaught live antigen …
Matched Description: … Bacillus calmette-guerin substrain connaught live antigen is intravesically administered for the treatment …
Matched Description: … Bacillus calmette-guerin substrain connaught live antigen is intravesically administered for the treatment …
Beremagene geperpavec
Beremagene geperpavec is a live, replication-defective herpes simplex virus type 1 (HSV-1)-based vector therapy. Developed by Krystal Biotech, it was first approved by the FDA on May 19, 2023, for the treatment of wounds associated with dystrophic epidermolysis bullosa (DEB). DEB is caused by mutations in the COL7A1 gene that...
Approved
Matched Synonyms: … Dna (recombinant herpes simplex virus type 1 strain kos plasmid vector kb103 human collagen col7a1-specifying …
Matched Description: … Beremagene geperpavec is a live, replication-defective herpes simplex virus type 1 (HSV-1)-based vector ... Beremagene geperpavec is genetically modified to deliver _COL7A1_, thereby restoring the levels of the COL7 protein …
Matched Description: … Beremagene geperpavec is a live, replication-defective herpes simplex virus type 1 (HSV-1)-based vector ... Beremagene geperpavec is genetically modified to deliver _COL7A1_, thereby restoring the levels of the COL7 protein …
Drotrecogin alfa
Drotrecogin alfa is activated human protein C that is synthesized by recombinant DNA technology. It is a glycoprotein of approximately 55 kilodalton molecular weight, consisting of a heavy chain and a light chain linked by a disulfide bond. Drotrecogin alfa was withdrawn from the market after a major study indicated...
Approved
Investigational
Withdrawn
Matched Synonyms: … Recombinant human activated protein C (rH-APC) ... Activated protein C …
Matched Description: … Drotrecogin alfa is activated human protein C that is synthesized by recombinant DNA technology. …
Matched Categories: … Recombinant Activated Protein C ... Protein Precursors …
Matched Description: … Drotrecogin alfa is activated human protein C that is synthesized by recombinant DNA technology. …
Matched Categories: … Recombinant Activated Protein C ... Protein Precursors …
Abatacept
Abatacept is a soluble fusion protein, which links the extracellular domain of human cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) to the modified Fc (hinge, CH2, and CH3 domains) portion of human immunoglobulin G1 (IgG1).[L20504,L42715] Structurally, abatacept is a glycosylated fusion protein with a MALDI-MS molecular weight of 92,300 Da and it...
Approved
Matched Synonyms: … Abatacept recombinant …
Matched Description: … [L20504,L42715] Structurally, abatacept is a glycosylated fusion protein with a MALDI-MS molecular weight ... Abatacept is a soluble fusion protein, which links the extracellular domain of human cytotoxic T-lymphocyte-associated ... It is produced through recombinant DNA technology in mammalian CHO cells. …
Matched Description: … [L20504,L42715] Structurally, abatacept is a glycosylated fusion protein with a MALDI-MS molecular weight ... Abatacept is a soluble fusion protein, which links the extracellular domain of human cytotoxic T-lymphocyte-associated ... It is produced through recombinant DNA technology in mammalian CHO cells. …
Insulin glulisine
Insulin glulisine is a short-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes. Insulin is typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human insulin, a peptide hormone produced by beta cells of the...
Approved
Matched Synonyms: … Insulin glulisine recombinant ... Insulin Glulisine (recombinant DNA origin) …
Matched Description: … Insulin also inhibits hepatic glucose production, enhances protein synthesis, and inhibits lipolysis ... This recombinant hormone differs from native human insulin in that the amino acid asparagine at position …
Matched Products: … APIDRA SOLOSTAR 100 UNITS/ML, SOLUTION FOR INJECTION IN A PRE-FILLED PEN ... Apidra SoloStar 100 Units/ml Solution for injection in a pre-filled pen …
Matched Description: … Insulin also inhibits hepatic glucose production, enhances protein synthesis, and inhibits lipolysis ... This recombinant hormone differs from native human insulin in that the amino acid asparagine at position …
Matched Products: … APIDRA SOLOSTAR 100 UNITS/ML, SOLUTION FOR INJECTION IN A PRE-FILLED PEN ... Apidra SoloStar 100 Units/ml Solution for injection in a pre-filled pen …
Rotavirus vaccine
Rotavirus commonly infects children and infants causing severe diarrhea and vomiting leading to potentially fatal dehydration. Two rotavirus vaccines are available for the prevention of rotavirus gastroenteritis, Rotateq and Rotarix. Rotateq is a live vaccine consisting of 5 reassorted human-bovine viral strains. Rotarix is a live attenuated vaccine containing the...
Approved
Matched Synonyms: … Rota virus, live attenuated …
Matched Salts name: … Human Rotavirus A type G1P(8) strain RIX4414 live antigen ... Human Rotavirus A type G1P7(5) strain WI79 live antigen ... Human Rotavirus A type G2P7(5) strain SC2 live antigen ... Human Rotavirus A type G4P7(5) strain BRB live antigen ... Human Rotavirus A type G3P7(5) strain WI78 live antigen …
Matched Categories: … rota virus, live attenuated ... Rota Virus Diarrhea Vaccines …
Matched Salts name: … Human Rotavirus A type G1P(8) strain RIX4414 live antigen ... Human Rotavirus A type G1P7(5) strain WI79 live antigen ... Human Rotavirus A type G2P7(5) strain SC2 live antigen ... Human Rotavirus A type G4P7(5) strain BRB live antigen ... Human Rotavirus A type G3P7(5) strain WI78 live antigen …
Matched Categories: … rota virus, live attenuated ... Rota Virus Diarrhea Vaccines …
Glucagon
Glucagon is a 29 amino acid hormone used as a diagnostic aid in radiologic exams to temporarily inhibit the movement of the gastrointestinal tract and to treat severe hypoglycemia.[L7634,L7637,L7640,L7643,L8519] Glucagon raises blood sugar through activation of hepatic glucagon receptors, stimulating glycogenolysis and the release of glucose.[L7640,L7643]
Glucagon was granted FDA...
Approved
Matched Synonyms: … Glucagon recombinant ... Glucagon (recombinant dna origin) …
Matched Categories: … Protein Precursors …
Matched Products: … Gvoke PFS 1 mg Pre-filled Syringe ... Gvoke PFS 0.5 mg Pre-filled Syringe …
Matched Categories: … Protein Precursors …
Matched Products: … Gvoke PFS 1 mg Pre-filled Syringe ... Gvoke PFS 0.5 mg Pre-filled Syringe …
Flutemetamol (18F)
Flutemetamol (18F) is a PET scanning radiopharmaceutical containing the radionuclide fluorine-18. It is indicated for Positron Emission Tomography (PET) imaging of the brain to estimate β amyloid neuritic plaque density in adult patients with cognitive impairment who are being evaluated for Alzheimer's disease (AD) or other causes of cognitive decline.
Approved
Investigational
Matched Synonyms: … Flutemetamol F 18 ... Flutemetamol F-18 …
Matched Iupac: … 2-[3-(¹⁸F)fluoro-4-(methylamino)phenyl]-1,3-benzothiazol-6-ol …
Matched Iupac: … 2-[3-(¹⁸F)fluoro-4-(methylamino)phenyl]-1,3-benzothiazol-6-ol …
Ebola Zaire vaccine (live, attenuated)
Ebola virus vaccine is a vaccine used to prevent Ebola virus disease caused by Zaire ebolavirus in adults, prevent outbreaks, and reduce the extent of the virus spreading in case of outbreaks. Ebola virus disease, formerly known as Ebola hemorrhagic fever, is a rare but severe and often deadly disease....
Approved
Matched Synonyms: … Recombinant Vesicular Stomatitis Virus (rVSV) strain Indiana with a deletion of the VSV envelope glycoprotein ... (G) replaced with the Zaire Ebola Virus (ZEBOV) Kikwit 1995 strain surface glycoprotein (GP) …
Matched Description: … These may be accompanied by hypotension and respiratory, kidney and liver failure, as well as internal ... [L10854] By introducing the relatively inactive viral protein to the patient, the patient’s immune system ... Ebola virus vaccine is a vaccine used to prevent Ebola virus disease caused by _Zaire ebolavirus_ in …
Matched Description: … These may be accompanied by hypotension and respiratory, kidney and liver failure, as well as internal ... [L10854] By introducing the relatively inactive viral protein to the patient, the patient’s immune system ... Ebola virus vaccine is a vaccine used to prevent Ebola virus disease caused by _Zaire ebolavirus_ in …
Haemophilus influenzae type B strain 20752 capsular polysaccharide tetanus toxoid conjugate antigen
Haemophilus influenzae type b strain 20752 capsular polysaccharide tetanus toxoid conjugate antigen is an active immunization as a booster dose given intramuscularly to pediatric patients who have received a primary series with a Haemophilus b Conjugate Vaccine that is licensed for primarly immunization. The vaccine contains Haemophilus b capsular polysaccharide...
Approved
Investigational
Matched Name: … Haemophilus influenzae type B strain 20752 capsular polysaccharide tetanus toxoid conjugate antigen …
Matched Description: … Haemophilus influenzae type b strain 20752 capsular polysaccharide tetanus toxoid conjugate antigen is …
Matched Description: … Haemophilus influenzae type b strain 20752 capsular polysaccharide tetanus toxoid conjugate antigen is …
Conestat alfa
C1 Esterase Inhibitor (Recombinant) is a recombinant analogue of endogenous complement component-1 esterase inhibitor (rhC1INH), purified from the milk of transgenic rabbits. The primary function of endogenous C1INH is to regulate the activation of the complement and contact system pathways. It does this through inhibition of several target proteases within...
Approved
Investigational
Matched Synonyms: … C1 Inhibitor (Recombinant) ... Recombinant human C1-INH ... C1 Esterase Inhibitor (Recombinant) …
Matched Description: … C1 Esterase Inhibitor (Recombinant) is a recombinant analogue of endogenous complement component-1 esterase …
Matched Description: … C1 Esterase Inhibitor (Recombinant) is a recombinant analogue of endogenous complement component-1 esterase …
Anthrax vaccine
Anthrax vaccine is a vaccine used for the pre- or post-exposure prophylaxis of disease in those at high risk of, suspected or confirmed exposure to Bacillus anthracis. It is subcutaneously or intramuscularly administered. It is derived from cell-free filtrates of microaerophilic cultures of an avirulent, nonencapsulated strain of Bacillus anthracis...
Approved
Matched Synonyms: … Bacillus anthracis inactivated antigen ... Bacillus anthracis strain V770-NP1-R antigen ... Bacillus anthracis strain V770-NP1-R filtrate antigen …
Matched Description: … an avirulent, nonencapsulated strain of Bacillus anthracis which are grown in a chemically defined protein-free ... Anthrax vaccine is a vaccine used for the pre- or post-exposure prophylaxis of disease in those at high ... currently stored in the Strategic National Stockpile in preparation for an Anthrax terrorist attack or for pre-exposure …
Matched Description: … an avirulent, nonencapsulated strain of Bacillus anthracis which are grown in a chemically defined protein-free ... Anthrax vaccine is a vaccine used for the pre- or post-exposure prophylaxis of disease in those at high ... currently stored in the Strategic National Stockpile in preparation for an Anthrax terrorist attack or for pre-exposure …
Moroctocog alfa
Moroctocog alfa, also known as BDDrFVIII (B domain deleted recombinant factor VIII), is a recombinant DNA-based drug with functional characteristics comparable to those of endogenous coagulation Factor VIII, the essential human blood clotting protein that is impaired in Hemophilia A. Moroctocog alfa is identical in sequence to endogenously produced Factor...
Approved
Matched Synonyms: … B-domain deleted recombinant factor VIII ... Human factor VIII, recombinant B-domain deleted ... Antihemophilic factor recombinant plasma/albumin free …
Matched Description: … factor VIII-Fc fusion protein which has an extended half-life compared with conventional factor VIII ... Moroctocog alfa, also known as BDDrFVIII (B domain deleted recombinant factor VIII), is a recombinant ... amino acid, 170 kDa protein [FDA Label]. …
Matched Categories: … Protein Precursors ... Recombinant Proteins …
Matched Description: … factor VIII-Fc fusion protein which has an extended half-life compared with conventional factor VIII ... Moroctocog alfa, also known as BDDrFVIII (B domain deleted recombinant factor VIII), is a recombinant ... amino acid, 170 kDa protein [FDA Label]. …
Matched Categories: … Protein Precursors ... Recombinant Proteins …
Apadamtase alfa
Thrombotic thrombocytopenic purpura (TTP) is a rare blood clotting disorder characterized by thrombocytopenia, microangiopathic hemolytic anemia, and various degrees of organ damage. It may be inherited (congenital TTP; cTTP) or acquired due to autoantibodies (immune-mediated TTP; iTTP), although cTTP accounts for <5% of all cases of TTP. Patients with cTTP...
Approved
Investigational
Matched Synonyms: … ADAMTS13, recombinant-krhn ... Recombinant human adamts13 ... Metalloproteinase ADAMTS13 (human recombinant BAX930) …
Matched Description: … [A262071] Apadamtase alfa, sold under the brand name Adzynma (ADAMTS13, recombinant-krhn), was approved …
Matched Categories: … Recombinant Proteins …
Matched Description: … [A262071] Apadamtase alfa, sold under the brand name Adzynma (ADAMTS13, recombinant-krhn), was approved …
Matched Categories: … Recombinant Proteins …
Etanercept
Dimeric fusion protein consisting of the extracellular ligand-binding portion of the human 75 kilodalton (p75) tumor necrosis factor receptor (TNFR) linked to the Fc portion of human IgG1.[L14862,A216522] The Fc component of etanercept contains the CH2 domain, the CH3 domain and hinge region, but not the CH1 domain of IgG1....
Approved
Investigational
Matched Synonyms: … Recombinant human TNF …
Matched Description: … Dimeric fusion protein consisting of the extracellular ligand-binding portion of the human 75 kilodalton ... Etanercept is produced by recombinant DNA technology in a Chinese hamster ovary (CHO) mammalian cell …
Matched Products: … BENEPALI 50MG ILO IM F PEN ... ENBREL (PRE-FILLED SYRINGE) ... Enbrel Solution for Injection in a Pre-filled Pen 50mg …
Matched Description: … Dimeric fusion protein consisting of the extracellular ligand-binding portion of the human 75 kilodalton ... Etanercept is produced by recombinant DNA technology in a Chinese hamster ovary (CHO) mammalian cell …
Matched Products: … BENEPALI 50MG ILO IM F PEN ... ENBREL (PRE-FILLED SYRINGE) ... Enbrel Solution for Injection in a Pre-filled Pen 50mg …
Trimipramine
Tricyclic antidepressant similar to imipramine, but with more antihistaminic and sedative properties.
Approved
Matched Synonyms: … 10,11-dihydro-N,N,β-trimethyl-5H-dibenz[b,f]azepine-5-propanamine ... 5-(γ-dimethylamino-β-methylpropyl)-10,11-dihydro-5H-dibenzo[b,f]azepine ... 5-[3-(dimethylamino)-2-methylpropyl]-10,11-dihydro-5H-dibenz[b,f]azepine …
Thyrotropin alfa
Thyrotropin alfa is a recombinant form of thyroid stimulating hormone used in performing certain tests in patients who have or have had thyroid cancer. It is also used along with a radioactive agent to destroy remaining thyroid tissue in certain patients who have had their thyroid gland removed because of...
Approved
Vet approved
Matched Synonyms: … Recombinant thyrotropin alfa ... Recombinant Human Thyroid Stimulating Hormone …
Matched Description: … Thyrotropin alfa is a recombinant form of thyroid stimulating hormone used in performing certain tests …
Matched Description: … Thyrotropin alfa is a recombinant form of thyroid stimulating hormone used in performing certain tests …
rhThrombin
rhThrombin (recombinant human thrombin) is being developed by ZymoGenetics, Inc. as a general aid to achieving hemostasis during surgery. ZymoGenetics is developing rhThrombin, a recombinant form of human thrombin that is not derived from animal or human blood, as an aid to controlling bleeding during surgery. Thrombin is used in...
Approved
Investigational
Matched Synonyms: … Recombinant thrombin …
Matched Description: … rhThrombin (recombinant human thrombin) is being developed by ZymoGenetics, Inc. as a general aid to ... ZymoGenetics is developing rhThrombin, a recombinant form of human thrombin that is not derived from ... The production of recombinant proteins is not dependent on the availability of blood from animals or …
Matched Description: … rhThrombin (recombinant human thrombin) is being developed by ZymoGenetics, Inc. as a general aid to ... ZymoGenetics is developing rhThrombin, a recombinant form of human thrombin that is not derived from ... The production of recombinant proteins is not dependent on the availability of blood from animals or …
Susoctocog alfa
Intravenous susoctocog alfa is a recombinant, B-domain deleted, porcine sequence antihaemophilic factor VIII (FVIII) product that has recently been approved for the treatment of bleeding episodes in adults with acquired haemophilia A (AHA). AHA is a rare bleeding disorder that results in a prolonged clotting time as measured by the...
Approved
Investigational
Matched Synonyms: … Antihemophilic factor (recombinant) porcine sequence ... ANTIHEMOPHILIC FACTOR (RECOMBINANT), PORCINE SEQUENCE ... Porcine recombinant factor VIII B-domain truncated …
Matched Description: … autoantibodies neutralize circulating human factor VIII and create a functional deficiency of this procoagulant protein ... Intravenous susoctocog alfa is a recombinant, B-domain deleted, porcine sequence antihaemophilic factor ... It is the first recombinant porcine FVIII treatment approved for AHA that allows physicians to manage …
Matched Description: … autoantibodies neutralize circulating human factor VIII and create a functional deficiency of this procoagulant protein ... Intravenous susoctocog alfa is a recombinant, B-domain deleted, porcine sequence antihaemophilic factor ... It is the first recombinant porcine FVIII treatment approved for AHA that allows physicians to manage …
Scorpion (centruroides) immune Fab2 antivenin (equine)
Centruroides (scorpion) Immune F(ab')2 (equine) is a purified preparation of immune globulin F(ab’)2 fragments that are derived from plasma of the horses immunized with venom of C. noxius, C. l. limpidus, C. l. tecomanus, and C. s. suffusus. It is intravenously administered patients with clinical signs of scorpion envenomation so...
Approved
Matched Synonyms: … Centruroides (scorpion) Immune F(ab')2 (equine) ... Centruroides (scorpion) immune F(ab')2 (equine) injection ... Centruroides (scorpion) immune F(ab)2 intravenous (equine) …
Matched Description: … Centruroides (scorpion) Immune F(ab')2 (equine) is a purified preparation of immune globulin F(ab’)2 ... Severe scorpion stings may cause loss of muscle control and respiratory failure, warranting heavy sedation …
Matched Description: … Centruroides (scorpion) Immune F(ab')2 (equine) is a purified preparation of immune globulin F(ab’)2 ... Severe scorpion stings may cause loss of muscle control and respiratory failure, warranting heavy sedation …
Imipramine
Imipramine, the prototypical tricyclic antidepressant (TCA), is a dibenzazepine-derivative TCA. TCAs are structurally similar to phenothiazines. They contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individuals, imipramine does not affect mood or arousal, but may cause sedation. In depressed individuals, imipramine exerts...
Approved
Matched Synonyms: … 10,11-dihydro-N,N-dimethyl-5H-dibenz[b,f]azepine-5-propanamine ... 5-[3-(dimethylamino)propyl]-10,11-dihydro-5H-dibenz[b,f]azepine …
Loxapine
An antipsychotic agent used in schizophrenia. [PubChem]
Approved
Matched Synonyms: … 2-Chloro-11-(4-methyl-1-piperazinyl)dibenz[b,f][1,4]oxazepine …
Amoxapine
Amoxapine, the N-demethylated derivative of the antipsychotic agent loxapine, is a dibenzoxazepine-derivative tricyclic antidepressant (TCA). TCAs are structurally similar to phenothiazines. They contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individuals, amoxapine does not affect mood or arousal, but may cause sedation....
Approved
Matched Synonyms: … 2-Chloro-11-(1-piperazinyl)dibenz(b,f)(1,4)oxazepine …
Mianserin
A tetracyclic compound with antidepressant effects. Mianserin was previously available internationally, however in most markets it has been phased out in favour of mirtazapine.
Approved
Investigational
Matched Synonyms: … 1,2,3,4,10,14b-Hexahydro-2-methyldibenzo(c,f)pyrazino(1,2-a)azepine …
Displaying drugs 126 - 150 of 5058 in total