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Displaying drugs 126 - 150 of 11997 in total
Morphine, the main alkaloid of opium, was first obtained from poppy seeds in 1805. It is a potent analgesic, though its use is limited due to tolerance, withdrawal, and the risk of abuse. Morphine is still routinely used today, though there are a number of semi-synthetic opioids of varying strength...
Approved
Investigational
Matched Description: … Morphine was granted FDA approval in 1941.[L12114] ... Morphine, the main alkaloid of opium, was first obtained from poppy seeds in 1805. …
Matched Products: … Oramorph 10 mg - orale Lösung in Einzeldosisbehältern ... Oramorph 30 mg - orale Lösung in Einzeldosisbehältern ... Oramorph 100 mg - orale Lösung in Einzeldosisbehältern …
Indocyanine Green is a water soluble, tricarbocyanine dye with a peak spectral absorption at 800 nm. The chemical name for Indocyanine Green is 1 H-Benz[e]indolium, 2-[7-[1,3-dihydro-1,1-dimethyl-3-(4-sulfobutyl)-2H-benz[e] indol-2-ylidene]-1,3,5-heptatrienyl]-1,1-dimethyl-3-(4-sulfobutyl)-,hydroxide, inner salt, sodium salt. Indocyanine Green for Injection USP has a pH of approximately 6.5 when reconstituted. Each vial of Indocyanine Green for...
Approved
Investigational
Matched Categories: … Compounds used in a research, industrial, or household setting …
A metallic element of atomic number 30 and atomic weight 65.38. It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell division. Zinc deficiency is associated with anemia, short stature, hypogonadism, impaired wound...
Approved
Investigational
Matched Description: … important role in protein synthesis and in cell division. ... It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an ... In addition to the above, recent review articles have already demonstrated the important role of zinc …
Matched Mixtures name: … Zinc Lozenges With Vitamin C In A Nonmedicinal Base With Echinacea Lozenge ... C & D ... C-plus - Tab …
Rosuvastatin, also known as the brand name product Crestor, is a lipid-lowering drug that belongs to the statin class of medications, which are used to lower the risk of cardiovascular disease and manage elevated lipid levels by inhibiting the endogenous production of cholesterol in the liver. More specifically, statin medications...
Approved
Matched Description: … a sequence of metabolic reactions involved in the production of several compounds involved in lipid ... clinical studies to result in a 45.8% to 54.6% decreases in LDL cholesterol levels, which is about three-fold ... this class becoming one of the most widely prescribed medications in North America. …
Matched Categories: … Drugs Used in Diabetes …
Nilotinib, also known as AMN107, is a tyrosine kinase inhibitor under investigation as a possible treatment for chronic myelogenous leukemia (CML). A Phase I clinical trial in 2006 showed that this drug was relatively safe and offered significant therapeutic benefits in cases of CML which were found to be resistant...
Approved
Investigational
Matched Description: … benefits in cases of CML which were found to be resistant to treatment with imatinib (Gleevec), another ... A Phase I clinical trial in 2006 showed that this drug was relatively safe and offered significant therapeutic …
Maralixibat (also known as SHP625, LUM001, and lopixibat) is an ileal bile acid transporter inhibitor, like odevixibat.[A236823,A239249,L38834] Maralixibat is indicated for the treatment of cholestatic pruritus in patients with Alagille syndrome. Previously, patients with cholestatic pruritus associated with Alagille syndrome were treated with antihistamines, rifampin, ursodeoxycholic acid, cholestyramine, naltrexone, and...
Approved
Investigational
Matched Description: … [A236823,A239249,L38834] Maralixibat is indicated for the treatment of cholestatic pruritus in patients ... [L38834] In October 2022, the EMA's Committee for Medicinal Products for Human Use (CHMP) recommended ... maralixibat be granted marketing authorization for the treatment of cholestatic pruritus in patients …
Elbasvir is a direct-acting antiviral medication used as part of combination therapy to treat chronic hepatitis C, an infectious liver disease caused by infection with hepatitis C virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most common in...
Approved
Matched Description: … [A19626] In a computational target-based drug repurposing investigation published in April 2020, elbasvir ... an infectious liver disease caused by infection with hepatitis C virus (HCV). ... a direct-acting antiviral medication used as part of combination therapy to treat chronic hepatitis C, …
Matched Categories: … Treatments for Hepatitis C ... Hepatitis C Virus NS5A Inhibitor …
Human interferon beta is a polypeptide used in the management of relapsing forms of Multiple Sclerosis (MS), and was initially approved by the FDA in 1992. Multiple Sclerosis is a devastating neurodegenerative disease that is usually progressive and significantly debilitating with a profound impact on the quality of life. Interferon...
Approved
Investigational
Matched Description: … [L12078] Interferon-beta has been used in the past in clinical studies with other coronaviruses due to ... (MS), and was initially approved by the FDA in 1992. ... Human interferon beta is a polypeptide used in the management of relapsing forms of Multiple Sclerosis …
Daptomycin is a cyclic lipopeptide antibacterial agent with a broad spectrum of activity against Gram-positive bacteria, including methicillin-susceptible and -resistant Staphylococcus aureus (MSSA/MRSA) and vancomycin-resistant Enterococci (VRE).[A231379, A231384, L32534] Chemically, daptomycin comprises 13 amino acids, including several non-standard and D-amino acids, with the C-terminal 10 amino acids forming an ester-linked...
Approved
Investigational
Matched Description: … Chemically, daptomycin comprises 13 amino acids, including several non-standard and D-amino acids, with the C-terminal ... [A231374, L32534] Daptomycin was first discovered in the early 1980s by researchers at Eli Lilly in soil ... samples from Mount Ararat in Turkey. …
Matched Products: … Daptomycin in Sodium Chloride …
Haloperidol is a high potency first-generation (typical) antipsychotic and one of the most frequently used antipsychotic medications used worldwide. While haloperidol has demonstrated pharmacologic activity at a number of receptors in the brain, it exerts its antipsychotic effect through its strong antagonism of the dopamine receptor (mainly D2), particularly within...
Approved
Matched Description: … [A180625] The efficacy of haloperidol was first established in controlled trials in the 1960s. ... from drug interaction studies in vivo. ... [A180616] While haloperidol has demonstrated pharmacologic activity at a number of receptors in the brain …
Matched Products: … MYUNG IN HALOPERIDOL TABLET 1.5 mg ... MYUNG IN HALOPERIDOL INJECTION 5 mg/ml …
Miglustat, commonly marketed under the trade name Zavesca, is a drug used to treat Gaucher disease. It inhibits the enzyme glucosylceramide synthase, an essential enzyme for the synthesis of most glycosphingolipids. It is only used for patients who cannot be treated with enzyme replacement therapy with imiglucerase. Miglustat is now...
Approved
Matched Description: … Miglustat is now the first and only approved therapy for patients with Niemann-Pick disease type C (NP-C ... patients in the European Union, Brazil, and South Korea. ... Miglustat was first developed as an anti-HIV agent in the 1990s. …
Duchenne muscular dystrophy (DMD) is an X-linked recessive allelic disorder characterized by a lack of functional dystrophin protein, which leads to progressive ambulatory, pulmonary, and cardiac function and is invariably fatal. A related, albeit a less severe, form of muscular dystrophy known as Becker muscular dystrophy (BMD) is characterized by...
Approved
Investigational
Matched Description: … Although corticosteroids are effective in slowing disease progression in both DMD and BMD patients, they ... on further verification in confirmatory trials. ... [A218186, L15526] In this manner, PMOs are much less susceptible to endo- and exonucleases and exhibit …
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Description: … , or inactivated, through exposure to heat or chemicals such as formaldehyde 3. ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated …
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Description: … , or inactivated, through exposure to heat or chemicals such as formaldehyde 3. ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated …
Octocrylene is a compound often used as an additive in sun screen, and is thought to have skin moisturizing effects because of its emollient properties. What makes this chemical such a popular additive to sun block, is its ability to neutralize UV radiation dissipated by sunlight, and to minimize skin...
Approved
Investigational
Matched Description: … Octocrylene is a compound often used as an additive in sun screen, and is thought to have skin moisturizing ... Because of its effectiveness, the chemical has been approved across the globe for use in cosmetics and …
Matched Mixtures name: … Black Rice Platinum Absolute Youth SPF 15 ... Risarium Black Rice Extreme Age-defying Line Reducing Moisture Face Cream SPF 15 ... Vitamin Cream C plus C
Motixafortide is a cyclic peptide hematopoietic stem cell mobilizer used to improve stem cell collection prior to autologous transplantation. Hematopoietic stem cell transplantation (HSCT) is commonly employed in the context of hematologic cancers - high-dose chemotherapy regimens destroy cancerous blood cells, which are then replaced via infusion of the patient's...
Approved
Investigational
Matched Description: … of C-X-C Motif Chemokine Receptor 4 (CXCR4), a protein that helps to anchor stem cells to bone marrow ... [A261476] Motixafortide was approved by the FDA in September 2023, in combination with filgrastim ... , for use in stem cell mobilization prior to autologous stem cell transplant in patients with multiple …
Interferon alfa-n1 consists of purified, natural (n is for natural) alpha interferon subtypes, at least two of which are glycosylated. This differs from recombinant alpha interferons, which are individual non-glycosylated proteins produced from individual alpha interferon genes.
Approved
Investigational
An antiandrogen with about the same potency as cyproterone in rodent and canine species.
Approved
Investigational
Matched Description: … An antiandrogen with about the same potency as cyproterone in rodent and canine species. …
Colloidal oatmeal is produced by grinding fine granules of oatmeal and boiling it to extract the colloidal material. It contains high concentrations of starches and beta-glucan that exhibits water-absorbing properties. Phenols are also contained in colloidal oatmeal, which possess antioxidant and anti-inflammatory activities, as well as UV-absorbing activity. Colloidal oatmeal...
Approved
Nutraceutical
Matched Description: … It is available in topical products as a skin soothing agent. ... Phenols are also contained in colloidal oatmeal, which possess antioxidant and anti-inflammatory activities …
Matched Mixtures name: … Infinite Aloe All-IN-one Skin Care …
Matched Products: … 3-In-1 Relief CVS …
Histrelin is a gonadotropin-releasing hormone (GnRH) agonist that acts as a potent inhibitor of gonadotropin when administered as an implant delivering continuous therapeutic doses. This drug is a synthetic analog of naturally occurring GnRH with a higher potency. Histrelin implants are non-biodegradable, diffusion-controlled, hydrogel polymer reservoirs containing histrelin acetate that...
Approved
Withdrawn
Matched Description: … the FDA in May 2007). ... L41755] Initially, histrelin implants were developed to reduce testosterone to castration levels in ... As the product Supprelin LA, histrelin is indicated for the treatment of CPP in children (approved by …
Beractant is a pulmonary surfactant used for the treatment of Respiratory Distress Syndrome (RDS) in premature infants. Considered a natural source of surfactant as it is made from bovine lung extract, beractant contains a mixture of phospholipids, neutral lipids, fatty acids, and surfactant-associated proteins such as SP-B and SP-C. The...
Approved
Matched Description: … It is suspended in 0.9% sodium chloride solution, and heat-sterilized. ... phospholipids, neutral lipids, fatty acids, and surfactant-associated proteins such as SP-B and SP-C. ... the leading cause of death in preterm infants. …
A benzimidazole broad-spectrum anthelmintic structurally related to mebendazole that is effective against many diseases. (From Martindale, The Extra Pharmacopoeia, 30th ed, p38)
Approved
Vet approved
Matched Products: … MESIN -C 200 MG / 5ML ORAL SUSPENSION …
Oprelvekin, the active ingredient in Neumega®, is recombinant Interleukin-11 (IL-11), which is produced in Escherichia coli (E. coli) by recombinant DNA technology. With a molecular mass of approximately 19,000 daltons, the non-glycosylated protein is 177 amino acids in length in comparison to the natural IL-11, which is 178 amino acid...
Approved
Investigational
Matched Description: … In mice and nonhuman primate studies of animals with moderate and severe myelosuppression, in addition ... in Escherichia coli (E. coli) by recombinant DNA technology. ... length in comparison to the natural IL-11, which is 178 amino acid long. …
Centruroides (scorpion) Immune F(ab')2 (equine) is a purified preparation of immune globulin F(ab’)2 fragments that are derived from plasma of the horses immunized with venom of C. noxius, C. l. limpidus, C. l. tecomanus, and C. s. suffusus. It is intravenously administered patients with clinical signs of scorpion envenomation so...
Approved
Matched Description: … noxius*, *C. l. limpidus*, *C. l. tecomanus*, and *C. s. suffusus*. ... immune globulin F(ab’)2 fragments that are derived from plasma of the horses immunized with venom of *C. ... It was approved by FDA in 2011 and is marketed under the name Anascorp [L2196]. …
N-acetyltyrosine, also referred to as N-acetyl-L-tyrosine, is used in place of as a tyrosine precursor. DB00135 is a non-essential amino acid with a polar side group. N-acetyltyrosine is administered as parenteral nutrition or intravenous infusion due to its enhanced solubility compared to tyrosine . It is typically administered as a...
Approved
Matched Description: … N-acetyltyrosine, also referred to as N-acetyl-L-tyrosine, is used in place of as a tyrosine precursor …
Matched Mixtures name: … Aminosyn II in Dextrose ... Aminosyn II in Dextrose ... Aminosyn II in Dextrose …
Displaying drugs 126 - 150 of 11997 in total