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Displaying drugs 1476 - 1500 of 1775 in total

Trastuzumab deruxtecan

Trastuzumab deruxtecan is a HER2-directed antibody attached to a topoisomerase inhibitor that is approved for use in certain types of treatment-resistant HER2-positive cancers. It is classified as an antibody-drug conjugate. The cleavable peptide linker used to bind the antibody and drug in this product distinguishes it from other members of...
Approved
Investigational
Matched Description: … The cleavable peptide linker used to bind the antibody and drug in this product distinguishes it from ... A188988] Trastuzumab deruxtecan was developed by Daiichi Sankyo in collaboration with AstraZeneca and ... Trastuzumab deruxtecan is a HER2-directed antibody attached to a topoisomerase inhibitor that is approved for …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Matched Products: … ENHERTU POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION 100MG/VIAL …

Risankizumab

Risankizumab is a fully humanized IgG1 monoclonal antibody (mAb) directed against interleukin 23 (IL-23). It gained its first global approval in Japan in March 2019, followed by approval in Canada, the US, and Europe in April 2019. Risankizumab is used to treat plaque psoriasis, psoriatic arthritis, and Crohn's disease.[L39885,L44191,L44231] Risankizumab...
Approved
Investigational
Matched Description: … It gained its first global approval in Japan in March 2019, followed by approval in Canada, the US, and ... [A254716] Risankizumab is used to treat plaque psoriasis, psoriatic arthritis, and Crohn's disease. ... [L39885,L44191,L44231] Risankizumab is being investigated for atopic dermatitis.[A254716] …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Skin and Mucous Membrane Agents …
Matched Products: … Skyrizi 75 mg solution for injection in pre-filled syringe ... SKYRIZI SOLUTION FOR INJECTION IN PRE-FILLED PEN 150MG/ML ... SKYRIZI SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 150MG/ML …

(2r)-2-{[Formyl(Hydroxy)Amino]Methyl}Hexanoic Acid

Experimental
Matched Name: … (2r)-2-{[Formyl(Hydroxy)Amino]Methyl}Hexanoic Acid …

Prilocaine

A local anesthetic that is similar pharmacologically to lidocaine. Currently, it is used most often for infiltration anesthesia in dentistry. (From AMA Drug Evaluations Annual, 1992, p165)
Approved
Matched Description: … Currently, it is used most often for infiltration anesthesia in dentistry. …
Matched Mixtures name: … Citanest Forte ... Citanest Forte DENTAL ... 4% Citanest Forte Dental With Epinephrine 1:200,000 …
Matched Products: … TAKIPRIL SOLUTION FOR INJECTION 20MG/ML ... Takipril 20mg/ml Solution for Injection …

Cholestyramine

Cholestyramine or colestyramine is a bile acid sequestrant. Bile acid sequestrants are polymeric compounds which serve as ion exchange resins. Cholestyramine resin is quite hydrophilic, but insoluble in water.
Approved
Investigational
Matched Categories: … Medications that reduce magnesium levels ... Hypolipidemic Agents Indicated for Hyperlipidemia ... Non-statin Hypolipidemic Agents Indicated for Hyperlipidemia …
Matched Products: … Cholestyramine Powder for Suspension ... Cholestyramine for Oral Suspension ... PHL-cholestyramine Powder for Suspension 400gm/can …

Amiodarone

Amiodarone is a benzofuran derivative, anti-arrhythmic drug used commonly in a variety of settings. Most known for its approved indication in life-threatening ventricular arrhythmias, it is also used off-label in the outpatient and inpatient setting for atrial fibrillation. Because of its ability to cause serious toxicity and possibly death, amiodarone...
Approved
Investigational
Matched Description: … used off-label in the outpatient and inpatient setting for atrial fibrillation. ... Because of its ability to cause serious toxicity and possibly death, amiodarone use should be reserved ... for its approved indications, according to prescribing information. …
Matched Categories: … Metabolic Side Effects of Drugs and Substances ... Calcium Channel Blockers ... Sodium Channel Blockers ... Potassium Channel Blockers ... Medications that reduce magnesium levels …
Matched Products: … DIOLUX CONCENTRATE FOR SOLUTION FOR INJECTION 50MG/ML ... Amiodarone for Injection 50mg/ml ... Amiodarone Hydrochloride for Injection …

Gadoteric acid

Gadoteric acid, commonly used in the salt form gadoterate meglumine, is a macrocyclic, ionic gadolinium-based contrast agent (GBCA). It is composed of the organic acid DOTA (1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid) used for its chelating properties, and gadolinium (Gd3+). Gadoterate meglumine has one of the highest thermodynamic stability, apparent stability, and kinetic stability,...
Approved
Matched Description: … tissues in adult and pediatric patients (2 years of age and older) to detect and visualize areas with ... its chelating properties, and gadolinium (Gd3+). ... disruption of the blood-brain barrier (BBB) and/or abnormal vascularity. …
Matched Products: … DOTAGRAF SOLUTION FOR INJECTION 0.5 MMOL/ML ... CLARISCAN SOLUTION FOR INJECTION IN VIAL 0.5 MMOL/ML ... CLARISCAN SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 0.5 MMOL/ML …

Pegfilgrastim

Pegfilgrastim is a PEGylated form of the recombinant human granulocyte colony-stimulating factor (G-CSF) analogue, filgrastim. The drug is approved for use to decrease the incidence of infection, as manifested by febrile neutropenia, in susceptible patients with with non-myeloid cancer receiving myelosuppressive anti-cancer treatment. Although the risk of developing febrile neutropenia...
Approved
Matched Description: … pharmacokinetic profile and conditions of use. ... than 20% in many readily used chemotherapy regimens,[A248855] infections pose risks of hospitalization and ... [A29,A187607] Due to a longer half-life and slower elimination rate than filgrastim, pegfilgrastim requires …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins …
Matched Products: … Pelgraz 6 mg solution for injection in a pre-filled syringe ... Pelgraz Solution for Injection in pre-filled syringe 6mg/0.6mL ... Filpegla 6 mg / 0.6 mL Solution for Injection in Pre-filled Syringe …

Ranibizumab

Ranibizumab is a recombinant humanized IgG1 kappa isotype monoclonal antibody fragment directed against human vascular endothelial growth factor A (VEGF-A), which is a glycoprotein implicated in the pathophysiology of age-related macular degeneration.[A2301, L38978] Ranibizumab is used to treat various ocular disorders with abnormal growth of blood vessels, such as neovascular...
Approved
Matched Description: … , and Health Canada respectively. ... [L41429] It is marketed under the brand names LUCENTIS and SUSVIMO. ... after [bevacizumab], another anti-VEGF anticancer drug, was discovered to inhibit neovascularization and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … Lucentis 10mg/ml Solution for Injection ... ACCENTRIX 10MG/ML SOLUTION FOR INJECTION ... LUCENTIS 10 MG/ML SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE …

Belimumab

Belimumab is a fully human recombinant IgG1λ monoclonal antibody that inhibits soluble human B lymphocyte stimulator protein (BLyS, also referred to as BAFF and TNFSF13B), a B cell survival factor. BLyS levels are often elevated in immunodeficient and autoimmune disorders, such as systemic lupus erythematosus (SLE).[A251495, L42705] By binding to...
Approved
Matched Description: … antibody that inhibits soluble human B lymphocyte stimulator protein (BLyS, also referred to as BAFF and ... [A251520] It is currently used to treat SLE and lupus nephritis.[L42630] ... [L42630] BLyS levels are often elevated in immunodeficient and autoimmune disorders, such as systemic …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Products: … Benlysta Powder for Solution for Infusion 120mg ... Benlysta Powder for Solution for Infusion 400mg …

Flumazenil

Fumazenil is an imidazobenzodiazepine derivative and a potent benzodiazepine receptor antagonist that competitively inhibits the activity at the benzodiazepine recognition site on the GABA/benzodiazepine receptor complex, thereby reversing the effects of benzodiazepine on the central nervous system.
Approved
Matched Description: … Fumazenil is an imidazobenzodiazepine derivative and a potent benzodiazepine receptor antagonist that …
Matched Products: … Flumazenil Kabi 0.1 mg/mL Solution for Injection ... FLUMAZENIL-BAXTER SOLUTION FOR INJECTION 1 MG/10 ML ... FLUMAZENIL-BAXTER SOLUTION FOR INJECTION 0.5 MG/5 ML …

Lanreotide

Lanreotide is a drug employed in the management of acromegaly (a hormonal condition caused by excess growth hormone) in addition to symptoms caused by neuroendocrine tumors, especially carcinoid syndrome. This drug is a long-acting analog of the drug somatostatin, a growth hormone inhibitor. Lanreotide is manufactured by the company, Ipsen...
Approved
Matched Description: … Lanreotide is manufactured by the company, _Ipsen Pharmaceuticals_ as lanreotide acetate, and marketed ... It is approved in several countries worldwide, including the United Kingdom, Australia, and Canada. ... Lanreotide was first approved for use in the United States by the FDA on August 30, 2007. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Pituitary and Hypothalamic Hormones and Analogues ... Somatostatin and Analogues ... Sex Hormones and Insulins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Somatuline Autogel 120mg, prolonged-release solution for injection in a pre-filled syringe ... Somatuline Autogel 60mg, prolonged-release solution for injection in a pre-filled syringe ... Somatuline Autogel 90mg, prolonged-release solution for injection in a pre-filled syringe …

Isavuconazonium

Isavuconazonium is a second-generation triazole antifungal approved on March 6, 2015 by the FDA and July 2015 by the EMA for the treatment of adults with invasive aspergillosis and invasive mucormycosis, marketed by Astellas under the brand Cresemba. It is the prodrug form of isavuconazole, the active moiety, and it...
Approved
Investigational
Matched Description: … [A38834] It is the prodrug form of isavuconazole, the active moiety, and it is available in oral and ... 2015 by the EMA for the treatment of adults with invasive aspergillosis and invasive mucormycosis, marketed ... Isavuconazonium is a second-generation triazole antifungal approved on March 6, 2015 by the FDA and July …
Matched Salts name: … Isavuconazonium sulfate …
Matched Categories: … Isavuconazole and Prodrugs …
Matched Products: … CRESEMBA POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION 200MG …

Dulaglutide

Dulaglutide, marketed by Eli Lilly as Trulicity, is a once-weekly subcutaneous glucagon-like peptide-1 (GLP-1) receptor agonist designed using recombinant DNA technology; it has been approved as an adjunct therapy to diet and exercise in the management of 2 diabetes (T2DM). Dulaglutide was initially approved by the FDA in 2014, and...
Approved
Investigational
Matched Description: … [A236070] Dulaglutide was initially approved by the FDA in 2014, and in February 2020 was approved for ... use in patients with T2DM and multiple cardiovascular risk factors for the prevention of cardiovascular ... agonist designed using recombinant DNA technology; it has been approved as an adjunct therapy to diet and …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Trulicity 1.5mg solution for injection in pre-filled pen ... Trulicity 0.75mg solution for injection in pre-filled pen …

Peginterferon alfa-2a

Peginterferon alfa-2a is a form of recombinant interferon used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most...
Approved
Investigational
Matched Description: … 36% for genotype 1 and 59% for genotypes 2-6 after 48 weeks of treatment. ... development of endocrine and autoimmune disorders, retinopathies, cardiovascular and neuropsychiatric ... categorized into nine distinct genotypes, with genotype 1 being the most common in the United States, and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Treatments for Hepatitis C ... Intercellular Signaling Peptides and Proteins …
Matched Products: … PEGASYS PRE-FILLED SYRINGE FOR INJECTION 180 mcg/0.5 ml ... PEGASYS PRE-FILLED SYRINGE FOR INJECTION 135 mcg/0.5 ml …

Mitomycin

Mitomycin is an antineoplastic antibiotic first isolated by Japanese microbiologists in the 1950s from cultures of Streptomyces caespitosus.[L12867,A193419] It is an alkylating agent that inhibits DNA synthesis (and, at higher concentrations, RNA and protein synthesis) by cross-linking the complementary strands of the DNA double helix. Few other antibiotics have been...
Approved
Matched Description: … [L12867,A193419] It is an alkylating agent that inhibits DNA synthesis (and, at higher concentrations ... , RNA and protein synthesis) by cross-linking the complementary strands of the DNA double helix. ... of cancers - the most recent of which is an April 2020 approval for its use in low-grade Upper Tract …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Indicators and Reagents ... Cytotoxic Antibiotics and Related Substances …
Matched Products: … MITONCO 10mg powder for solution for injection/infusion or intravesical ... Mitomycin for Injection ... Mitomycin for Injection USP …

Pentamidine

Antiprotozoal agent effective in trypanosomiasis, leishmaniasis, and some fungal infections; used in treatment of pneumocystis pneumonia in HIV-infected patients. It may cause diabetes mellitus, central nervous system damage, and other toxic effects.
Approved
Investigational
Matched Description: … Antiprotozoal agent effective in trypanosomiasis, leishmaniasis, and some fungal infections; used in ... It may cause diabetes mellitus, central nervous system damage, and other toxic effects. …
Matched Categories: … Agents Against Leishmaniasis and Trypanosomiasis ... Antiparasitic Products, Insecticides and Repellents ... Antibiotics for Pneumocystis Pneumonia ... Medications that reduce magnesium levels …
Matched Products: … Pentamidine Isetionate for Injection BP ... DBL™ PENTAMIDINE ISETHIONATE FOR INJECTION BP 300mg ... DBL PENTAMIDINE ISETHIONATE FOR INJECTION BP 300 mg/vial …

2,3,6A,7,8,9-HEXAHYDRO-11H-[1,4]DIOXINO[2,3-G]PYRROLO[2,1-B][1,3]BENZOXAZIN-11-ONE

Experimental
Matched Name: … 2,3,6A,7,8,9-HEXAHYDRO-11H-[1,4]DIOXINO[2,3-G]PYRROLO[2,1-B][1,3]BENZOXAZIN-11-ONE …

Pyridoxine

Pyridoxine is the 4-methanol form of vitamin B6, an important water-soluble vitamin that is naturally present in many foods. As its classification as a vitamin implies, Vitamin B6 (and pyridoxine) are essential nutrients required for normal functioning of many biological systems within the body. While many plants and microorganisms are...
Approved
Investigational
Nutraceutical
Vet approved
Matched Description: … , pyridoxal 5'-phosphate and pyridoxamine 5'-phosphate. ... pyridoxine, pyridoxal, and pyridoxamine, and their phosphorylated derivatives, pyridoxine 5'-phosphate ... Vitamin B6, principally in its biologically active coenzyme form pyridoxal 5'-phosphate, is involved …
Matched Mixtures name: … Isotonix Advanced B-complex Vitamins With Potassium and Magnesium ... Feminique W Iron and Calcium Tab ... Levomefolate Calcium, Cyanocobalamin and Pyridoxine Hydrochloride …
Matched Categories: … Alimentary Tract and Metabolism ... Diet, Food, and Nutrition ... isoniazid, sulfamethoxazole, trimethoprim and pyridoxine ... Antiinfectives for Systemic Use ... Drugs for Treatment of Tuberculosis …
Matched Products: … LIBAVIT-B 6 FORT AMPUL, 3 ADET ... LIBAVIT-B 6 FORT AMPUL, 50 ADET ... LIBAVIT-B 6 FORT AMPUL, 25 ADET …

Furosemide

Furosemide is a potent loop diuretic that acts on the kidneys to ultimately increase water loss from the body. It is an anthranilic acid derivative. Furosemide is used for edema secondary to various clinical conditions, such as congestive heart failure exacerbation, liver failure, renal failure, and high blood pressure. It...
Approved
Vet approved
Matched Description: … In addition to oral formulations, the solution for intravenous and intramuscular administration is also ... Furosemide has a fast onset and short duration of action and has been used safely and effectively in ... both pediatric and adult patients. …
Matched Mixtures name: … SPIRO COMP FORTE RAT100/20 ... SPIRO COMP FORTE RAT100/20 ... SPIRO COMP FORTE RAT100/20 …
Matched Salts name: … Furosemide sodium …
Matched Categories: … Sodium Potassium Chloride Symporter Inhibitors ... furosemide and potassium ... furosemide and potassium-sparing agents ... High-Ceiling Diuretics and Potassium-Sparing Agents ... Medications that reduce magnesium levels …
Matched Products: … DIRINE FORTE (INJECTION) ... FUROSEMIDE-BAXTER SOLUTION FOR INJECTION 50 MG/5 ML ... FUROSEMIDE-BAXTER SOLUTION FOR INJECTION 20 MG/2 ML …

Carbetocin

Carbetocin is a drug used to control postpartum hemorrhage, bleeding after giving birth. It is an analogue of oxytocin, and its action is similar to that of oxytocin -- it causes contraction of the uterus.
Approved
Investigational
Matched Description: … It is an analogue of oxytocin, and its action is similar to that of oxytocin -- it causes contraction …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Pituitary and Hypothalamic Hormones and Analogues ... Oxytocin and Analogues ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Sex Hormones and Insulins …
Matched Products: … DURATOCIN RTS SOLUTION FOR INJECTION 100 MCG/ML ... Pharmidea Carbetocin 100 microgram/ml solution for injection …

Fosaprepitant

Fosaprepitant is an intravenously administered antiemetic drug. It is a prodrug of Aprepitant. It aids in the prevention of acute and delayed nausea and vomiting associated with chemotherapy treatment.
Approved
Matched Description: … It aids in the prevention of acute and delayed nausea and vomiting associated with chemotherapy treatment …
Matched Categories: … Aprepitant and Prodrugs …
Matched Products: … Powder for Solution for Infusion 150mg …

Bupivacaine

Bupivacaine is a widely used local anesthetic agent.
Approved
Investigational
Matched Mixtures name: … Sensorcaine Forte ... Bupivacaine Hci and Epinephrine ... Bupivacaine Hydrochloride and Epinephrine …
Matched Salts name: … Bupivacaine hydrochloride anhydrous …
Matched Categories: … bupivacaine and meloxicam …
Matched Products: … Regivell Heavy 0.5% Solution for Injection ... Bupicaine D 0.5% w/v Solution for Injection ... BUPIVACAINE-BAXTER SOLUTION FOR INJECTION 5 MG/ML …

Benzyl benzoate

Benzyl benzoate is one of the older preparations used to treat scabies. Scabies is a skin infection caused by the mite sarcoptes scabiei. It is characterised by severe itching (particularly at night), red spots, and may lead to a secondary infection. Benzyl benzoate is lethal to this mite and so...
Approved
Matched Description: … It is also used to treat lice infestation of the head and body. ... Benzyl benzoate is lethal to this mite and so is useful in the treatment of scabies. ... It is characterised by severe itching (particularly at night), red spots, and may lead to a secondary …
Matched Categories: … Antiparasitic Products, Insecticides and Repellents ... Scabicides, Insecticides and Repellents …
Matched Products: … SCABİN %25 FORT LİKİT …

Trabectedin

Trabectedin, also referred as ET-743 during its development, is a marine-derived antitumor agent discovered in the Carribean tunicate Ecteinascidia turbinata and now produced synthetically. Trabectedin has a unique mechanism of action. It binds to the minor groove of DNA interfering with cell division and genetic transcription processes and DNA repair...
Approved
Investigational
Matched Description: … It is approved for use in Europe, Russia and South Korea for the treatment of advanced soft tissue sarcoma ... and DNA repair machinery. ... and ovarian cancer. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … YONDELIS 1MG FOR INJECTION ... YONDELIS Powder for Injection 1mg/vial …
Displaying drugs 1476 - 1500 of 1775 in total