Displaying drugs 1476 - 1500 of 2624 in total
Nafamostat
Nafamostat is a synthetic serine protease inhibitor that is commonly formulated with hydrochloric acid due to its basic properties. It has been used in trials studying the prevention of Liver Transplantation and Postreperfusion Syndrome. The use of nafamostat in Asian countries is approved as an anticoagulant therapy for patients undergoing...
Investigational
Matched Synonyms: … p-Guanidinobenzoic acid ester with 6-hydroxy-2-naphthamidine …
Matched Description: … It has been used in trials studying the prevention of Liver Transplantation and Postreperfusion Syndrome ... Nafamostat is a synthetic serine protease inhibitor that is commonly formulated with hydrochloric acid …
Matched Description: … It has been used in trials studying the prevention of Liver Transplantation and Postreperfusion Syndrome ... Nafamostat is a synthetic serine protease inhibitor that is commonly formulated with hydrochloric acid …
Ferrous ascorbate
Approved
Matched Synonyms: … L-Ascorbic acid, iron complex …
Matched Categories: … Blood and Blood Forming Organs ... Diet, Food, and Nutrition ... Acids, Acyclic ... Sugar Acids ... Hydroxy Acids …
Matched Categories: … Blood and Blood Forming Organs ... Diet, Food, and Nutrition ... Acids, Acyclic ... Sugar Acids ... Hydroxy Acids …
BGA002
Investigational
Matched Synonyms: … 16 base single stranded peptide nucleic acid oligonucleotide - 7 aminoacids peptide …
Dichlorvos
Dichlorvos or 2,2-dichlorovinyl dimethyl phosphate is a drug of the organophosphate class, frequently used as an insecticide for the control of indoor pests and for the protection of stored products from insect infestations. The compound has been available on the market since 1961 and its use is a controversial topic...
Vet approved
Matched Synonyms: … Phosphoric acid, 2,2-dichlorovinyl dimethyl ester ... Phosphoric acid, 2,2-dichloroethenyl dimethyl ester …
Matched Description: … , and cancer. ... environmental and health concerns. ... of the _organophosphate_ class, frequently used as an insecticide for the control of indoor pests and …
Matched Description: … , and cancer. ... environmental and health concerns. ... of the _organophosphate_ class, frequently used as an insecticide for the control of indoor pests and …
Clofibrate
A fibric acid derivative used in the treatment of hyperlipoproteinemia type III and severe hypertriglyceridemia. (From Martindale, The Extra Pharmacopoeia, 30th ed, p986)
Approved
Investigational
Matched Synonyms: … 2-(4-Chlorophenoxy)-2-methylpropanoic acid ethyl ester ... alpha-(p-Chlorophenoxy)isobutyric acid, ethyl ester ... 2-(p-Chlorophenoxy)-2-methylpropionic acid ethyl ester …
Matched Description: … A fibric acid derivative used in the treatment of hyperlipoproteinemia type III and severe hypertriglyceridemia …
Matched Categories: … Acids, Acyclic ... Clofibric Acid ... Carboxylic Acids ... Fibric Acids …
Matched Description: … A fibric acid derivative used in the treatment of hyperlipoproteinemia type III and severe hypertriglyceridemia …
Matched Categories: … Acids, Acyclic ... Clofibric Acid ... Carboxylic Acids ... Fibric Acids …
(R)-etodolac
Investigational
Matched Synonyms: … (1r)-1,8-diethyl-1,3,4,9-tetrahydropyrano(3,4-b)indole-1-acetic acid ... Pyrano(3,4-b)indole-1-acetic acid, 1,8-diethyl-1,3,4,9-tetrahydro-, (1r)- ... Pyrano(3,4-b)indole-1-acetic acid, 1,8-diethyl-1,3,4,9-tetrahydro-, (r)- …
1,8-Di-Hydroxy-4-Nitro-Xanthen-9-One
Experimental
Matched Name: … 1,8-Di-Hydroxy-4-Nitro-Xanthen-9-One …
Matched Iupac: … 1,8-dihydroxy-4-nitro-9H-xanthen-9-one …
Matched Iupac: … 1,8-dihydroxy-4-nitro-9H-xanthen-9-one …
Sulindac
Sulindac is a nonsteroidal anti-inflammatory drug (NSAID) of the arylalkanoic acid class that is marketed by Merck under the brand name Clinoril. Like other NSAIDs, it may be used in the treatment of acute or chronic inflammatory conditions. Sulindac is a prodrug, derived from sulfinylindene, that is converted in vivo...
Approved
Investigational
Matched Synonyms: … cis-5-Fluoro-2-methyl-1-((p-methylsulfinyl)benzylidene)indene-3-acetic acid ... (Z)-5-Fluoro-2-methyl-1-((p-(methylsulfinyl)phenyl)methylene)-1H-indene-3-acetic acid ... cis-5-Fluoro-2-methyl-1-((4-(methylsulfinyl)phenyl)methylene)-1H-indene-3-acetic acid …
Matched Iupac: … 2-[(1Z)-5-fluoro-1-[(4-methanesulfinylphenyl)methylidene]-2-methyl-1H-inden-3-yl]acetic acid …
Matched Description: … levels of the compound without inducing gastrointestinal effects, where the drug is excreted in the bile and ... is thought to primarily mediate its action by inhibiting prostaglandin synthesis by inhibiting COX-1 and ... Sulindac is a nonsteroidal anti-inflammatory drug (NSAID) of the arylalkanoic acid class that is marketed …
Matched Categories: … Acetic Acid Derivatives and Related Substances ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Iupac: … 2-[(1Z)-5-fluoro-1-[(4-methanesulfinylphenyl)methylidene]-2-methyl-1H-inden-3-yl]acetic acid …
Matched Description: … levels of the compound without inducing gastrointestinal effects, where the drug is excreted in the bile and ... is thought to primarily mediate its action by inhibiting prostaglandin synthesis by inhibiting COX-1 and ... Sulindac is a nonsteroidal anti-inflammatory drug (NSAID) of the arylalkanoic acid class that is marketed …
Matched Categories: … Acetic Acid Derivatives and Related Substances ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
5-[[trans-4-[4-(trifluoromethoxy)phenyl]cyclohexyl]oxy]-1H-1,2,3-triazole-4-carboxylic acid
Investigational
Matched Synonyms: … 5-((trans-4-(4-(trifluoromethoxy)phenyl)cyclohexyl)oxy)-1h-1,2,3-triazole-4-carboxylic acid ... 5-[[trans-4-[(trifluoromethoxy)phenyl]cyclohexyl]oxy]-1H-1,2,3-triazole-4-carboxylic acid …
Matched Name: … 5-[[trans-4-[4-(trifluoromethoxy)phenyl]cyclohexyl]oxy]-1H-1,2,3-triazole-4-carboxylic acid …
Matched Iupac: … 5-{[(1r,4r)-4-[4-(trifluoromethoxy)phenyl]cyclohexyl]oxy}-1H-1,2,3-triazole-4-carboxylic acid …
Matched Name: … 5-[[trans-4-[4-(trifluoromethoxy)phenyl]cyclohexyl]oxy]-1H-1,2,3-triazole-4-carboxylic acid …
Matched Iupac: … 5-{[(1r,4r)-4-[4-(trifluoromethoxy)phenyl]cyclohexyl]oxy}-1H-1,2,3-triazole-4-carboxylic acid …
Acitretin
An oral retinoid effective in the treatment of psoriasis. It is the major metabolite of etretinate with the advantage of a much shorter half-life when compared with etretinate.
Approved
Matched Synonyms: … (all-E)-9-(4-Methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-2,4,6,8-nonatetraenoic acid ... all-trans-3,7-Dimethyl-9-(4-methoxy-2,3,6-trimethylphenyl)-2,4,6,8-nonatetraenoic acid …
Matched Iupac: … (2E,4E,6E,8E)-9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethylnona-2,4,6,8-tetraenoic acid …
Matched Categories: … Skin and Mucous Membrane Agents …
Matched Iupac: … (2E,4E,6E,8E)-9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethylnona-2,4,6,8-tetraenoic acid …
Matched Categories: … Skin and Mucous Membrane Agents …
Indomethacin
Indometacin, or indomethacin, is a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic properties. NSAIDs consist of agents that are structurally unrelated; the NSAID chemical classification of indometacin is an indole-acetic acid derivative with the chemical name 1- (p-chlorobenzoyl)25-methoxy-2-methylindole-3-acetic acid. The pharmacological effect of indometacin is not fully understood,...
Approved
Investigational
Matched Synonyms: … 1-(p-chlorobenzoyl)-5-methoxy-2-methylindole-3-acetic acid ... {1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1H-indol-3-yl}acetic acid …
Matched Iupac: … 2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetic acid …
Matched Description: … Drug Administration in 1965, [A486] along with other acetic acid derivatives such as [diclofenac] and ... thromboxane biosynthesis via the arachidonic acid (AA) pathway. ... Indometacin was first discovered in 1963 and it was first approved for use in the U.S. by the Food and …
Matched Categories: … Acetic Acid Derivatives and Related Substances ... Antiinflammatory and Antirheumatic Products ... indometacin and antiinfectives ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Topical Products for Joint and Muscular Pain …
Matched Iupac: … 2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetic acid …
Matched Description: … Drug Administration in 1965, [A486] along with other acetic acid derivatives such as [diclofenac] and ... thromboxane biosynthesis via the arachidonic acid (AA) pathway. ... Indometacin was first discovered in 1963 and it was first approved for use in the U.S. by the Food and …
Matched Categories: … Acetic Acid Derivatives and Related Substances ... Antiinflammatory and Antirheumatic Products ... indometacin and antiinfectives ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Topical Products for Joint and Muscular Pain …
Methyl vanillate
Experimental
Matched Synonyms: … Vanillic acid, methyl ester ... 4-hydroxy-3-methoxybenzoic acid methyl ester …
Matched Categories: … Hydroxy Acids ... Acids, Carbocyclic ... Carboxylic Acids …
Matched Categories: … Hydroxy Acids ... Acids, Carbocyclic ... Carboxylic Acids …
Aspartame
Flavoring agent sweeter than sugar, metabolized as phenylalanine and aspartic acid.
Investigational
Nutraceutical
Matched Synonyms: … 3-Amino-N-(α-methoxycarbonylphenethyl) succinamic acid ... 3-Amino-N-(alpha-methoxycarbonylphenethyl) succinamic acid ... 3-Amino-N-(α-carboxyphenethyl)succinamic acid N-methyl ester …
Matched Iupac: … (3S)-3-amino-3-{[(2S)-1-methoxy-1-oxo-3-phenylpropan-2-yl]carbamoyl}propanoic acid …
Matched Description: … Flavoring agent sweeter than sugar, metabolized as phenylalanine and aspartic acid. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Diet, Food, and Nutrition …
Matched Iupac: … (3S)-3-amino-3-{[(2S)-1-methoxy-1-oxo-3-phenylpropan-2-yl]carbamoyl}propanoic acid …
Matched Description: … Flavoring agent sweeter than sugar, metabolized as phenylalanine and aspartic acid. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Diet, Food, and Nutrition …
L-alloisoleucine
Experimental
Matched Synonyms: … (2S,3R)-2-amino-3-methylpentanoic acid …
Matched Iupac: … (2S,3R)-2-amino-3-methylpentanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Branched-Chain …
Matched Iupac: … (2S,3R)-2-amino-3-methylpentanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Branched-Chain …
Diisopropyl methylphosphonate
Experimental
Matched Synonyms: … Methylphosphonic acid bis(1-methylethyl)ester …
3'-Uridinemonophosphate
Experimental
Matched Synonyms: … 3'-Uridylic acid …
Matched Iupac: … 4-hydroxy-5-(4-hydroxy-2-oxo-1,2-dihydropyrimidin-1-yl)-2-(hydroxymethyl)oxolan-3-yl]oxy}phosphonic acid …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Iupac: … 4-hydroxy-5-(4-hydroxy-2-oxo-1,2-dihydropyrimidin-1-yl)-2-(hydroxymethyl)oxolan-3-yl]oxy}phosphonic acid …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Cetyl palmitate
Experimental
Matched Synonyms: … Hexadecanoic acid, hexadecyl ester …
Matched Categories: … Fatty Acids ... Palmitic Acids …
Matched Categories: … Fatty Acids ... Palmitic Acids …
Dynasore
Experimental
Matched Synonyms: … 3-Hydroxynaphthalene-2-carboxylic acid (3,4-dihydroxybenzylidene)hydrazide …
Lithium carbonate
Lithium has been used to treat manic episodes since the 19th century . Though it is widely used, its mechanism of action is still unknown[FDA Label][A14585,A176642,A176651,L5843]. Lithium carbonate has a narrow therapeutic range and so careful monitoring is required to avoid adverse effects[FDA Label].
Approved
Matched Synonyms: … Carbonic acid, dilithium salt …
Matched Description: … Lithium carbonate has a narrow therapeutic range and so careful monitoring is required to avoid adverse …
Matched Categories: … Acids ... Carbonic Acid ... Acids, Noncarboxylic …
Matched Description: … Lithium carbonate has a narrow therapeutic range and so careful monitoring is required to avoid adverse …
Matched Categories: … Acids ... Carbonic Acid ... Acids, Noncarboxylic …
Lumiracoxib
Lumiracoxib is a COX-2 selective non-steroidal anti-inflammatory drug (NSAID). On August 11, 2007, Australia's Therapeutic Goods Administration (TGA, the Australian equivalent of the FDA) cancelled the registration of lumiracoxib in Australia due to concerns that it may cause liver failure. New Zealand and Canada have also followed suit in recalling...
Approved
Investigational
Matched Synonyms: … 2-((2-chloro-6-fluorophenyl)amino)-5-methylbenzeneacetic acid …
Matched Iupac: … 2-{2-[(2-chloro-6-fluorophenyl)amino]-5-methylphenyl}acetic acid …
Matched Description: … New Zealand and Canada have also followed suit in recalling the drug. …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Acids, Carbocyclic ... Carboxylic Acids …
Matched Iupac: … 2-{2-[(2-chloro-6-fluorophenyl)amino]-5-methylphenyl}acetic acid …
Matched Description: … New Zealand and Canada have also followed suit in recalling the drug. …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Acids, Carbocyclic ... Carboxylic Acids …
(2Z)-2-(Benzoylamino)-3-[4-(2-bromophenoxy)phenyl]acrylic acid
Experimental
Matched Synonyms: … (2Z)-2-(benzoylamino)-3-[4-(2-bromophenoxy)phenyl]-2-propenoic acid …
Matched Name: … (2Z)-2-(Benzoylamino)-3-[4-(2-bromophenoxy)phenyl]acrylic acid …
Matched Iupac: … (2Z)-3-[4-(2-bromophenoxy)phenyl]-2-(phenylformamido)prop-2-enoic acid …
Matched Name: … (2Z)-2-(Benzoylamino)-3-[4-(2-bromophenoxy)phenyl]acrylic acid …
Matched Iupac: … (2Z)-3-[4-(2-bromophenoxy)phenyl]-2-(phenylformamido)prop-2-enoic acid …
Guanosine-2'-monophosphate
Experimental
Matched Synonyms: … 2'-guanylic acid …
Matched Iupac: … )-2-(2-amino-6-oxo-6,9-dihydro-1H-purin-9-yl)-4-hydroxy-5-(hydroxymethyl)oxolan-3-yl]oxy}phosphonic acid …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Iupac: … )-2-(2-amino-6-oxo-6,9-dihydro-1H-purin-9-yl)-4-hydroxy-5-(hydroxymethyl)oxolan-3-yl]oxy}phosphonic acid …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Arbaclofen
Arbaclofen, or STX209, is the R-enantiomer of baclofen. It is believed to be a selective gamma-amino butyric acid type B receptor agonist, and has been investigated as a treatment for autism spectrum disorder and fragile X syndrome in randomized, double blind, placebo controlled trials. It has also been investigated as...
Investigational
Matched Synonyms: … (R)-4-amino-3-(4-chlorophenyl)butanoic acid …
Matched Iupac: … (3R)-4-amino-3-(4-chlorophenyl)butanoic acid …
Matched Description: … It is believed to be a selective gamma-amino butyric acid type B receptor agonist, and has been investigated ... as a treatment for autism spectrum disorder and fragile X syndrome in randomized, double blind, placebo ... It has also been investigated as a treatment for spasticity due to multiple sclerosis and spinal cord …
Matched Iupac: … (3R)-4-amino-3-(4-chlorophenyl)butanoic acid …
Matched Description: … It is believed to be a selective gamma-amino butyric acid type B receptor agonist, and has been investigated ... as a treatment for autism spectrum disorder and fragile X syndrome in randomized, double blind, placebo ... It has also been investigated as a treatment for spasticity due to multiple sclerosis and spinal cord …
Cinalukast
Used in the treatment of asthma, cinalukast selectively antagonizes leukotriene D4 (LTD4) at the cysteinyl leukotriene receptor, CysLT1, in the human airway. Cinalukast inhibits the actions of LTD4 at the CysLT1 receptor, preventing airway edema, smooth muscle contraction, and enhanced secretion of thick, viscous mucus.
Experimental
Matched Synonyms: … 3'-((E)-2-(4-cyclobutyl-2-thiazolyl)vinyl)-2,2-diethylsuccinanilic acid …
Matched Iupac: … 3-({3-[(E)-2-(4-cyclobutyl-1,3-thiazol-2-yl)ethenyl]phenyl}carbamoyl)-2,2-diethylpropanoic acid …
Matched Description: … inhibits the actions of LTD4 at the CysLT1 receptor, preventing airway edema, smooth muscle contraction, and …
Matched Categories: … Sulfur Compounds …
Matched Iupac: … 3-({3-[(E)-2-(4-cyclobutyl-1,3-thiazol-2-yl)ethenyl]phenyl}carbamoyl)-2,2-diethylpropanoic acid …
Matched Description: … inhibits the actions of LTD4 at the CysLT1 receptor, preventing airway edema, smooth muscle contraction, and …
Matched Categories: … Sulfur Compounds …
Phosphorylcolamine
Experimental
Matched Synonyms: … Colamine phosphoric acid …
Matched Iupac: … (2-aminoethoxy)phosphonic acid …
Matched Iupac: … (2-aminoethoxy)phosphonic acid …
Displaying drugs 1476 - 1500 of 2624 in total