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Displaying drugs 1476 - 1500 of 2063 in total

Zilovertamab

Investigational
Matched Synonyms: … Immunoglobulin g1, anti-(human receptor tyrosine kinase ror-1) (human-mus musculus monoclonal uc-961 ... .gamma.1-chain), disulfide with human-mus musculus monoclonal uc-961 .kappa. …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Stapokibart

Stapokibart is under investigation in clinical trial NCT06424470 (Study on the Treatment of Prurigo Nodularis With Stapokibart Injection).
Investigational
Matched Synonyms: … Immunoglobulin G4 [227-proline], anti-(human interleukin 4 receptor subunit α) (human-Mus musculus monoclonal ... CM310 γ4-chain), disulfide with human-Mus musculus monoclonal CM310 κ-chain, dimer …

Pagibaximab

Investigational
Matched Synonyms: … ), DISULFIDE WITH HUMAN-MOUSE MONOCLONAL .KAPPA. ... chain), disulfide with human-mouse monoclonal κ-chain, dimer ... HEAVY CHAIN), DISULFIDE WITH HUMAN MOUSE MONOCLONAL HU96 110 .KAPPA. …
Matched Categories: … Amino Acids, Peptides, and Proteins …

CTX130

CTX130 is an allogeneic CRISPR/Cas9-mediated genetically modified CAR T cell therapy targeting CD70 antigen.
Investigational
Matched Synonyms: … Allogeneic CRISPR/Cas9-mediated genetically modified CAR T cells targeting CD70 antigen …
Matched Description: … CTX130 is an allogeneic CRISPR/Cas9-mediated genetically modified CAR T cell therapy targeting CD70 antigen …

Urokinase

Urokinase is an endogenous peptide that is cleaved in the presence of plasmin between lysine 158 and isoleucine 159 to yield active urokinase. Urokinase remains connected between these 2 chains by a sulfhydryl bond. Urokinase was granted FDA approval on 16 January 1978.
Approved
Investigational
Withdrawn
Matched Description: … Urokinase is an endogenous peptide that is cleaved in the presence of plasmin between lysine 158 and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Enzymes and Coenzymes …
Matched Products: … Kinlytic Open-cath …

Talditercept alfa

Talditercept alfa is under investigation in clinical trial NCT03039686 (Clinical Trial to Evaluate the Efficacy, Safety, and Tolerability of RO7239361 in Ambulatory Boys With Duchenne Muscular Dystrophy).
Investigational
Matched Synonyms: … protein with adnectin, anti-(human growth differentiation factor 8) (human clone bms-986089 fibronectin ... Bivalent Anti-Human Myostatin Adnectin-Igg1 ... Bms-986089 (fully human anti-myostatin adnectin) …
Matched Description: … under investigation in clinical trial NCT03039686 (Clinical Trial to Evaluate the Efficacy, Safety, and …

Dostarlimab

Dostarlimab is an IgG4 humanized monoclonal antibody targeted against the human programmed death receptor-1 (PD-1). PD-1 receptors are found on T-cells and, when activated, serve to inhibit immune responses - some cancers leverage this system by overexpressing PD-1 ligands, thereby effectively inhibiting the anti-tumor immune response that would typically attempt...
Approved
Investigational
Matched Synonyms: … Immunoglobulin G4, anti-programmed cell death protein 1 (PDCD1) (humanized clone ABT1 gamma4-chain), …
Matched Description: … immune-mediated anti-tumor activity and may therefore be used to treat a wide variety of cancers, including ... [L33320] PD-1 receptors are found on T-cells and, when activated, serve to inhibit immune responses - ... those of the skin, lung, kidneys, and liver. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES ... PD-1/PD-L1 (Programmed cell death protein 1/death ligand 1) inhibitors ... PD-1/PDL-1 (Programmed cell death protein 1/death ligand 1) inhibitors …

Endostar

Endostar is under investigation for the treatment of Nasopharyngeal Carcinoma. Endostar has been investigated for the treatment of Non-small Cell Lung Cancer.
Investigational
Matched Synonyms: … Recombinant human endostatin protein ... N-TERMINAL-MGGSHHHHH-ENDOSTATIN (HUMAN RECOMBINANT) …
Matched Description: … Endostar has been investigated for the treatment of Non-small Cell Lung Cancer. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …

Cefoperazone

Cefoperazone is a semisynthetic broad-spectrum cephalosporin proposed to be effective against Pseudomonas infections. It is a third-generation antiobiotic agent and it is used in the treatment of various bacterial infections caused by susceptible organisms in the body, including respiratory tract infections, peritonitis, skin infections, endometritis, and bacterial septicemia. While its...
Approved
Investigational
Matched Description: … It is a third-generation antiobiotic agent and it is used in the treatment of various bacterial infections ... organisms in the body, including respiratory tract infections, peritonitis, skin infections, endometritis, and …
Matched Mixtures name: … CEFOPERAZONE SODIUM - SULBACTAM SODIUM ... CEFOPERAZONE SODIUM - SULBACTAM SODIUM ... CEFOPERAZONE SODIUM - SULBACTAM SODIUM …
Matched Salts name: … Cefoperazone sodium …
Matched Products: … CEFOPERAZONE SODIUM …

Ceftizoxime

A semisynthetic cephalosporin antibiotic which can be administered intravenously or by suppository. The drug is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range of both aerobic and anaerobic gram-positive and gram-negative organisms. It has few side effects and is reported to be safe...
Approved
Withdrawn
Matched Description: … A semisynthetic cephalosporin antibiotic which can be administered intravenously or by suppository. ... of both aerobic and anaerobic gram-positive and gram-negative organisms. ... It has few side effects and is reported to be safe and effective in aged patients and in patients with …
Matched Salts name: … Ceftizoxime sodium …
Matched Products: … CEFTIZOXIME SODIUM …

Aldesleukin

Aldesleukin, a lymphokine, is produced by recombinant DNA technology using a genetically engineered E. coli strain containing an analog of the human interleukin-2 gene. Genetic engineering techniques were used to modify the human IL-2 gene, and the resulting expression clone encodes a modified human interleukin-2. This recombinant form differs from...
Approved
Matched Synonyms: … Recombinant human interleukin-2 ... Recombinant interleukin-2 human ... 125-L-serine-2-133-interleukin 2 (human reduced) …
Matched Description: … Genetic engineering techniques were used to modify the human IL-2 gene, and the resulting expression ... clone encodes a modified human interleukin-2. ... recombinant DNA technology using a genetically engineered E. coli strain containing an analog of the human …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins ... Increased Lymphocyte Cell Production …
Matched Products: … Proleukin 18 x 10 6 IE - Pulver zur Herstellung einer Injektions- oder Infusionslösung …

Clesrovimab

Clesrovimab is under investigation in clinical trial NCT04938830 (Clesrovimab (MK-1654) in Infants and Children at Increased Risk for Severe Respiratory Syncytial Virus (RSV) Disease (MK-1654-007)).
Investigational
Matched Synonyms: … f protein) (human monoclonal rb1 .gamma.1-chain), disulfide with human monoclonal rb1 .kappa. ... Immunoglobulin g1 (262-tyrosine,264-threonine,266-glutamic acid), anti-(human respiratory syncytial virus …
Matched Description: … Clesrovimab is under investigation in clinical trial NCT04938830 (Clesrovimab (MK-1654) in Infants and …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Teropavimab

Teropavimab is under investigation in clinical trial NCT05729568 (A Study of GS-5423 and GS-2872 in Combination With Capsid Inhibitor Lenacapavir in Virologically Suppressed Adults With HIV-1 Infection).
Investigational
Matched Synonyms: … ) (human monoclonal 8c11-62a12 .gamma.1-chain), disulfide with human monoclonal 8c11-62a12 .kappa. ... Immunoglobulin g1 (434-leucine,440-serine), anti-(human immunodeficiency virus 1 envelope protein gp120env …
Matched Description: … Teropavimab is under investigation in clinical trial NCT05729568 (A Study of GS-5423 and GS-2872 in Combination …

VIS-410

VIS-410 is under investigation in clinical trial NCT03040141 (Study of Efficacy and Safety of IV VIS410 Plus Oseltamivir Versus Oseltamivir in Hospitalized Adults With Influenza A).
Investigational
Matched Synonyms: … WITH HUMAN MONOCLONAL VIS410 .KAPPA. ... IMMUNOGLOBULIN G1, ANTI-(INFLUENZA HEMAGGLUTININ) (HUMAN MONOCLONAL VIS410 .GAMMA.1-CHAIN), DISULFIDE …
Matched Description: … VIS-410 is under investigation in clinical trial NCT03040141 (Study of Efficacy and Safety of IV VIS410 …

o-Cymen-5-ol

Experimental
Matched Products: … NORO-X Forming HandSoap ... NORO-X Foaming HandSoap …

Depelestat

Investigational
Matched Synonyms: … Proteinase inhibitor m/nei (synthetic human) ... Recombinant human neutrophil inhibitor (hne) ... Human recombinant neutrophil elastase inhibitor, homologue of the second kunitz domain of inter-alpha-trypsin …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Paclitaxel

Paclitaxel is a chemotherapeutic agent marketed under the brand name Taxol among others. Used as a treatment for various cancers, paclitaxel is a mitotic inhibitor that was first isolated in 1971 from the bark of the Pacific yew tree which contains endophytic fungi that synthesize paclitaxel. It is available as...
Approved
Vet approved
Matched Description: … It is available as an intravenous solution for injection and the newer formulation contains albumin-bound ... paclitaxel is a mitotic inhibitor that was first isolated in 1971 from the bark of the Pacific yew tree …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... paclitaxel and encequidar …
Matched Products: … Paclitaxel Protein Bound Particles Albumin Bound ... Paclitaxel protein-bound particles for injectable suspension (albumin-bound) ... Paclitaxel Protein-Bound Particles for Injectable Suspension (Albumin-Bound) …

Domvanalimab

Domvanalimab is under investigation in clinical trial NCT05502237 (Zimberelimab and Domvanalimab in Combination With Chemotherapy Versus Pembrolizumab With Chemotherapy in Patients With Untreated Metastatic Non-small Cell Lung Cancer).
Investigational
Matched Synonyms: … Immunoglobulin g1 (236-alanine,237-alanine,de-c-terminal-lysine), anti-(human receptor tigit)(human-mus ... musculus monoclonal ab154 .gamma.1-chain), disulfide with human-mus musculus monoclonal ab154 .kappa …
Matched Description: … Domvanalimab is under investigation in clinical trial NCT05502237 (Zimberelimab and Domvanalimab in Combination ... Chemotherapy Versus Pembrolizumab With Chemotherapy in Patients With Untreated Metastatic Non-small Cell …

Epinephrine

Epinephrine, also known as adrenaline, is a hormone and neurotransmitter and produced by the adrenal glands that can also be used as a drug due to its various important functions. Though it has long been used in the treatment of hypersensitivity reactions, epinephrine in the auto-injector form (EpiPen) has been...
Approved
Vet approved
Matched Description: … Epinephrine, also known as _adrenaline_, is a hormone and neurotransmitter and produced by the adrenal ... It can be used in severe cases of croup [L4824]. ... Many new products/biosimilars and dosage routes have been approved under various names over the last …
Matched Mixtures name: … Lidocaine Hydrochloride and Epinephrine ... Lidocaine Hydrochloride and Epinephrine ... Lidocaine Hydrochloride and Epinephrine …
Matched Categories: … Adrenergic and Dopaminergic Agents ... Alpha-and Beta-adrenergic Agonists ... Antiglaucoma Preparations and Miotics ... Epinephrine and similars ... epinephrine and other drugs for obstructive airway diseases …
Matched Products: … Gingi-pak Max Z-twist No 1 ... Gingi-pak Max Z-twist No 2 ... Gingi-pak Max Z-twist No 3 …

Avizakimab

Avizakimab is under investigation in clinical trial NCT03371251 (Study of BOS161721 in Systemic Lupus Erythematosus (SLE) Patients on a Background of Limited Standard of Care).
Investigational
Matched Synonyms: … Immunoglobulin g1 (251-tyrosine,253-threonine,255-glutamic acid), anti-(human interleukin 21) (human-mus ... musculus monoclonal bos161721 .gamma.1-chain), disulfide with human-mus musculus monoclonal bos161721 …
Matched Description: … Avizakimab is under investigation in clinical trial NCT03371251 (Study of BOS161721 in Systemic Lupus …

Tick-borne encephalitis vaccine (whole virus, inactivated)

Tick-borne encephalitis (TBE) is a disease caused by the TBE virus (TBEV), transmitted by ticks from the genus Ixodes. The disease course is variable. Some patients will be asymptomatic or experience a mild febrile illness, while others will experience the full course including neurological symptoms. TBE often manifests in a...
Approved
Matched Name: … Tick-borne encephalitis vaccine (whole virus, inactivated) …
Matched Description: … and then propagated in chicken embryo fibroblast (CEF) cells, since the 1990's, the whole process has ... Some patients will be asymptomatic or experience a mild febrile illness, while others will experience ... last for years and rare chronic forms of the disease have also been noted. …

Neoantigen specific TCR-T cell therapy

Investigational
Matched Name: … Neoantigen specific TCR-T cell therapy …

Azathioprine

Azathioprine is a prodrug of 6-mercaptopurine, first synthesized in 1956 by Gertrude Elion, William Lange, and George Hitchings in an attempt to produce a derivative of 6-mercaptopurine with a better therapeutic index.[A189678,A189687,A189690] Azathioprine is used to treat inflammatory conditions like rheumatoid arthritis and as an immunosuppressant in the prevention of...
Approved
Matched Description: … Azathioprine is a prodrug of 6-mercaptopurine, first synthesized in 1956 by Gertrude Elion, William Lange, and ... and as an immunosuppressant in the prevention of renal transplant rejection. ... [A189678,A189687,A189690] Azathioprine is used to treat inflammatory conditions like rheumatoid arthritis …
Matched Salts name: … Azathioprine sodium …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Nucleic Acids, Nucleotides, and Nucleosides …
Matched Products: … Azathioprine Sodium ... Azathioprine Sodium for Injection …

Typhoid Vaccine Live

Salmonella typhi Ty21a live antigen is a live attenuated vaccine for oral administration only. It contains the attenuated strain Salmonella typhi Ty21a. The vaccine prevents the development of typhoid fever, an acute, febrile enteric disease caused by Salmonella typhi by inducing a local immune response in the intestinal tract.
Approved
Matched Products: … Vivotif 2 x 10^9 - 2 x 10^10 CFU magensaftresistente Hartkapsel …

Obinepitide

Obinepitide is a synthetic analogue of two natural human hormones, PYY and Pancreatic Polypeptide, which normally are released during a meal. These hormones are known to play a role in the regulation of food intake and appetite in man as satiety signal from the GI-tract to the CNS. In obinepitide,...
Investigational
Matched Synonyms: … (34-L-glutamine)pancreatic hormone (human) …
Matched Description: … Obinepitide is a synthetic analogue of two natural human hormones, PYY and Pancreatic Polypeptide, which ... These hormones are known to play a role in the regulation of food intake and appetite in man as satiety …
Displaying drugs 1476 - 1500 of 2063 in total