Displaying drugs 1501 - 1525 of 2560 in total
Vonafexor
Investigational
Matched Synonyms: … 2-benzofurancarboxylic acid, 4-chloro-5-(4-((2,6-dichlorophenyl)sulfonyl)-1-piperazinyl)- …
Adapalene
Acne vulgaris is a multifactorial disorder of the pilosebaceous unit involving increased sebum production, inflammation, and hyperproliferation/hyperkeratinization of the follicular infundibulum. It is also associated with Cutibacterium acnes (also known as Propionibacterium acnes). Adapalene is a third-generation topical retinoid used for the treatment of acne vulgaris. Adapalene has similar efficacy...
Approved
Matched Synonyms: … 6-(3-(1-Adamantyl)-4-methoxyphenyl)-2-naphthoic acid …
Matched Iupac: … 6-[3-(adamantan-1-yl)-4-methoxyphenyl]naphthalene-2-carboxylic acid …
Matched Description: … multifactorial disorder of the pilosebaceous unit involving increased sebum production, inflammation, and ... [A193521] [Tazarotene] is more efficacious than adapalene but is designated as pregnancy category X and ... can also be combined with benzoyl peroxide (BPO), which possesses bactericidal properties[A193524], and …
Matched Mixtures name: … Adapalene and Benzoyl Peroxide ... ADAPALENE and BENZOYL PEROXIDE ... Adapalene and Benzoyl Peroxide …
Matched Categories: … Skin and Mucous Membrane Agents …
Matched Iupac: … 6-[3-(adamantan-1-yl)-4-methoxyphenyl]naphthalene-2-carboxylic acid …
Matched Description: … multifactorial disorder of the pilosebaceous unit involving increased sebum production, inflammation, and ... [A193521] [Tazarotene] is more efficacious than adapalene but is designated as pregnancy category X and ... can also be combined with benzoyl peroxide (BPO), which possesses bactericidal properties[A193524], and …
Matched Mixtures name: … Adapalene and Benzoyl Peroxide ... ADAPALENE and BENZOYL PEROXIDE ... Adapalene and Benzoyl Peroxide …
Matched Categories: … Skin and Mucous Membrane Agents …
Ambrisentan
Ambrisentan is an orally active selective type A endothelin receptor antagonist indicated for the treatment of pulmonary arterial hypertension. It is approved in Europe, Canada and the United States for use as a single agent to improve exercise ability and delay clinical worsening. In addition, it is approved in the...
Approved
Investigational
Matched Synonyms: … (2S)-2-[(4,6-dimethylpyrimidin-2-yl)oxy]-3-methoxy- 3,3-diphenylpropanoic acid …
Matched Iupac: … (2S)-2-[(4,6-dimethylpyrimidin-2-yl)oxy]-3-methoxy-3,3-diphenylpropanoic acid …
Matched Description: … ability and delay clinical worsening. ... It is approved in Europe, Canada and the United States for use as a single agent to improve exercise ... Patients studied displayed symptoms and etiologies predominantly of WHO Functional Class II-III. …
Matched Categories: … ambrisentan and tadalafil ... Acids, Carbocyclic ... Carboxylic Acids …
Matched Iupac: … (2S)-2-[(4,6-dimethylpyrimidin-2-yl)oxy]-3-methoxy-3,3-diphenylpropanoic acid …
Matched Description: … ability and delay clinical worsening. ... It is approved in Europe, Canada and the United States for use as a single agent to improve exercise ... Patients studied displayed symptoms and etiologies predominantly of WHO Functional Class II-III. …
Matched Categories: … ambrisentan and tadalafil ... Acids, Carbocyclic ... Carboxylic Acids …
Abequolixron
Investigational
Matched Synonyms: … ((3r)-3-(((2-chloro-3-(trifluoromethyl)phenyl)methyl)(2,2- diphenylethyl)amino)butoxy)phenyl)acetic acid ... -((3r)-3-(((2-chloro-3-(trifluoromethyl)phenyl)methyl)(2,2-diphenylethyl)amino)butoxy)phenyl)acetic acid ... -[(3R)-3-({[2-chloro-3-(trifluoromethyl)phenyl]methyl}(2,2-diphenylethyl)amino)butoxy]phenyl}acetic acid …
Matched Iupac: … -[(3R)-3-({[2-chloro-3-(trifluoromethyl)phenyl]methyl}(2,2-diphenylethyl)amino)butoxy]phenyl}acetic acid …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids …
Matched Iupac: … -[(3R)-3-({[2-chloro-3-(trifluoromethyl)phenyl]methyl}(2,2-diphenylethyl)amino)butoxy]phenyl}acetic acid …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids …
Zomepirac
Zomepirac, formerly marketed as Zomax tablets, was associated with fatal and near-fatal anaphylactoid reactions. The manufacturer voluntarily removed Zomax tablets from the Canadian, US, and UK markets in March 1983.
Withdrawn
Matched Synonyms: … 5-(4-Chlorobenzoyl)-1,4-dimethyl-1H-pyrrole-2-acetic acid …
Matched Iupac: … 2-[5-(4-chlorobenzoyl)-1,4-dimethyl-1H-pyrrol-2-yl]acetic acid …
Matched Description: … Zomepirac, formerly marketed as Zomax tablets, was associated with fatal and near-fatal anaphylactoid ... The manufacturer voluntarily removed Zomax tablets from the Canadian, US, and UK markets in March 1983 …
Matched Salts name: … Zomepirac sodium ... Zomepirac sodium anhydrous …
Matched Categories: … Acetic Acid Derivatives and Related Substances ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Iupac: … 2-[5-(4-chlorobenzoyl)-1,4-dimethyl-1H-pyrrol-2-yl]acetic acid …
Matched Description: … Zomepirac, formerly marketed as Zomax tablets, was associated with fatal and near-fatal anaphylactoid ... The manufacturer voluntarily removed Zomax tablets from the Canadian, US, and UK markets in March 1983 …
Matched Salts name: … Zomepirac sodium ... Zomepirac sodium anhydrous …
Matched Categories: … Acetic Acid Derivatives and Related Substances ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Glucarpidase
Glucarpidase is a recombinant carboxypeptidase G2 produced by genetically modified Escherichia coli bacteria. It is a 390-amino acid homodimer protein. High-dose methotrexate, an antifolate agent, has been widely and safely used for many decades in treating various cancers; however, even with aggressive hydration, urine alkalinization, and leucovorin rescue, some patients...
Approved
Investigational
Matched Synonyms: … Pteroylmonoglutamic acid hydrolase G2 …
Matched Description: … It is a 390-amino acid homodimer protein. ... [L39855] High-dose [methotrexate], an antifolate agent, has been widely and safely used for many decades ... This can lead to delayed renal clearance of methotrexate and elevated drug plasma levels, increasing …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes …
Matched Description: … It is a 390-amino acid homodimer protein. ... [L39855] High-dose [methotrexate], an antifolate agent, has been widely and safely used for many decades ... This can lead to delayed renal clearance of methotrexate and elevated drug plasma levels, increasing …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes …
Indium In-111 pentetate
Indium In-111 pentetate disodium is a radioactive diagnostic indicated for use in radionuclide cisternography. Decay of In-111 by electron capture allows for detection with a gamma camera for visualization of the brain and spinal column.
Approved
Matched Synonyms: … Indium (111In) pentetic acid …
Matched Description: … In-111 by electron capture allows for detection with a gamma camera for visualization of the brain and …
Matched Categories: … indium (111In) pentetic acid …
Matched Description: … In-111 by electron capture allows for detection with a gamma camera for visualization of the brain and …
Matched Categories: … indium (111In) pentetic acid …
(5-hydroxyindolo[1,2-a]quinazolin-7-yl)acetic acid
Experimental
Matched Synonyms: … (5-oxo-5,6-dihydro-indolo[1,2-a]quinazolin-7-yl)-acetic acid …
Matched Name: … (5-hydroxyindolo[1,2-a]quinazolin-7-yl)acetic acid …
Matched Iupac: … 2-{5-oxo-5H,6H-indolo[1,2-a]quinazolin-7-yl}acetic acid …
Matched Name: … (5-hydroxyindolo[1,2-a]quinazolin-7-yl)acetic acid …
Matched Iupac: … 2-{5-oxo-5H,6H-indolo[1,2-a]quinazolin-7-yl}acetic acid …
S-Ethylisothiourea
S-Ethylisothiourea is a nitric oxide synthase inhibitor.
Experimental
Matched Synonyms: … CARBAMIMIDOTHIOIC ACID, ETHYL ESTER …
Matched Categories: … Hypnotics and Sedatives …
Matched Categories: … Hypnotics and Sedatives …
Cilomilast
Cilomilast (Ariflo, SB-207,499) is a drug which was developed for the treatment of respiratory disorders such as asthma and Chronic Obstructive Pulmonary Disease (COPD). It is orally active and acts as a selective Phosphodiesterase-4 inhibitor. Following four clinical trials, the drug proved to be effective in treating COPD, however it...
Investigational
Matched Synonyms: … cis-4-cyano-4-(3-(cyclopentyloxy)-4-methoxyphenyl)cyclohexanecarboxylic acid …
Matched Iupac: … (1s,4s)-4-cyano-4-[3-(cyclopentyloxy)-4-methoxyphenyl]cyclohexane-1-carboxylic acid …
Matched Description: … It is orally active and acts as a selective Phosphodiesterase-4 inhibitor. ... SB-207,499) is a drug which was developed for the treatment of respiratory disorders such as asthma and …
Matched Categories: … Carboxylic Acids ... Acids, Carbocyclic …
Matched Iupac: … (1s,4s)-4-cyano-4-[3-(cyclopentyloxy)-4-methoxyphenyl]cyclohexane-1-carboxylic acid …
Matched Description: … It is orally active and acts as a selective Phosphodiesterase-4 inhibitor. ... SB-207,499) is a drug which was developed for the treatment of respiratory disorders such as asthma and …
Matched Categories: … Carboxylic Acids ... Acids, Carbocyclic …
Avalglucosidase alfa
Avalglucosidase alfa, or NeoGAA, is a drug for enzyme replacement therapy specifically designed for Pompe disease, a rare inherited neuromuscular disorder caused by the deficiency of the alpha-glucosidase (GAA) enzyme. GAA is an essential enzyme that hydrolyzes glycogen into free glucose for use in cellular functions. In Pompe disease, the...
Approved
Investigational
Matched Synonyms: … Neo-recombinant human acid alpha-glucosidase …
Matched Description: … , especially in smooth, cardiac, and skeletal muscle cells. ... muscle weakness, which leads to premature death and debilitating effects on people’s lives. ... In Pompe disease, the GAA enzyme is missing and patients are unable to properly break down glycogen, …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
Matched Description: … , especially in smooth, cardiac, and skeletal muscle cells. ... muscle weakness, which leads to premature death and debilitating effects on people’s lives. ... In Pompe disease, the GAA enzyme is missing and patients are unable to properly break down glycogen, …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
Lithium citrate
Approved
Matched Synonyms: … Citric acid, trilithium salt …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... Tricarboxylic Acids …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... Tricarboxylic Acids …
Gluconolactone
Gluconolactone is a naturally-occurring food additive used as a sequestrant, an acidifier, or a curing, pickling, or leavening agent. It is a cyclic ester of D-gluconic acid. Pure gluconolactone is a white odorless crystalline powder.
Approved
Experimental
Matched Synonyms: … Gluconic acid lactone ... D-gluconic acid delta-lactone …
Matched Description: … It is a cyclic ester of D-gluconic acid. Pure gluconolactone is a white odorless crystalline powder. …
Matched Categories: … Acids, Acyclic ... Sugar Acids ... Hydroxy Acids ... Carboxylic Acids …
Matched Description: … It is a cyclic ester of D-gluconic acid. Pure gluconolactone is a white odorless crystalline powder. …
Matched Categories: … Acids, Acyclic ... Sugar Acids ... Hydroxy Acids ... Carboxylic Acids …
Allopurinol
Gout is a disease that occurs by the deposition of monosodium urate crystals (MSU) in body tissues, especially around joints . This disease has been well-documented in historical medical records and appears in the biographies of several prominent, historically recognized individuals .
Allopurinol is a xanthine oxidase enzyme inhibitor that...
Approved
Matched Description: … This disease has been well-documented in historical medical records and appears in the biographies of ... It was initially approved by the FDA in 1966 [L5674] and is now formulated by several manufacturers [ ... enzyme inhibitor that is considered to be one of the most effective drugs used to decrease urate levels and …
Matched Salts name: … Allopurinol sodium …
Matched Categories: … Preparations Inhibiting Uric Acid Production …
Matched Products: … Allopurinol sodium …
Matched Salts name: … Allopurinol sodium …
Matched Categories: … Preparations Inhibiting Uric Acid Production …
Matched Products: … Allopurinol sodium …
Oxfendazole
Oxfendazole is a sulfoxide metabolite of fenbendazole. This benzimidazole antihelminthic protects livestock from roundworm. strongyles, and pinworn.
Investigational
Vet approved
Matched Synonyms: … 5-(phenylsulfinyl)-2-benzimidazolecarbamic acid methyl ester ... (5-(phenylsulfinyl)-1H-benzimidazol-2-yl)carbamic acid methyl ester …
Matched Description: … This benzimidazole antihelminthic protects livestock from roundworm. strongyles, and pinworn. …
Matched Description: … This benzimidazole antihelminthic protects livestock from roundworm. strongyles, and pinworn. …
PXL-770 free acid anhydrous
Investigational
Matched Synonyms: … PXL770 free acid anhydrous ... PXL 770 free acid anhydrous …
Matched Name: … PXL-770 free acid anhydrous …
Matched Name: … PXL-770 free acid anhydrous …
CH-1504 L-isomer
CH-1504 L-isomer is under investigation in clinical trial NCT01116141 (A Study of CH-4051 in Patients With Rheumatoid Arthritis (RA)).
Investigational
Matched Synonyms: … 4-methylene-n-(4-(2-(2,4-diaminoquinazolin-6-yl)ethyl)benzoyl)-l-glutamic acid ... L-glutamic acid, n-(4-(2-(2,4-diamino-6-quinazolinyl)ethyl)benzoyl)-4-methylene- ... (2s)-2-((4-(2-(2,4-diaminoquinazolin-6-yl)ethyl)benzoyl)amino)-4-methylene-pentanedioic acid …
Cinoxacin
Synthetic antimicrobial related to oxolinic acid and nalidixic acid and used in urinary tract infections.
Approved
Investigational
Withdrawn
Matched Synonyms: … 1-ethyl-6,7-methylenedioxy-4(1H)-oxocinnoline-3-carboxylic acid ... 5-Ethyl-8-oxo-5,8-dihydro-1,3-dioxa-5,6-diaza-cyclopenta[b]naphthalene-7-carboxylic acid …
Matched Iupac: … 1-ethyl-4-oxo-1H,4H,7H-[1,3]dioxolo[4,5-g]cinnoline-3-carboxylic acid …
Matched Description: … Synthetic antimicrobial related to oxolinic acid and nalidixic acid and used in urinary tract infections …
Matched Categories: … Acids, Heterocyclic …
Matched Iupac: … 1-ethyl-4-oxo-1H,4H,7H-[1,3]dioxolo[4,5-g]cinnoline-3-carboxylic acid …
Matched Description: … Synthetic antimicrobial related to oxolinic acid and nalidixic acid and used in urinary tract infections …
Matched Categories: … Acids, Heterocyclic …
Indralin
Investigational
Matched Synonyms: … 2-thiophenecarboxylic acid, 5-((1e)-2-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)-1-propen ... 1e)-2-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)-1-propen-1-yl)-2-thiophenecarboxylic acid …
Matched Iupac: … 1E)-2-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)prop-1-en-1-yl]thiophene-2-carboxylic acid …
Matched Categories: … Receptors, Retinoic Acid, agonists …
Matched Iupac: … 1E)-2-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)prop-1-en-1-yl]thiophene-2-carboxylic acid …
Matched Categories: … Receptors, Retinoic Acid, agonists …
2-(3,4-Dihydroxyphenyl)Acetic Acid
A deaminated metabolite of levodopa. [PubChem]
Experimental
Matched Name: … 2-(3,4-Dihydroxyphenyl)Acetic Acid …
Matched Iupac: … 2-(3,4-dihydroxyphenyl)acetic acid …
Matched Iupac: … 2-(3,4-dihydroxyphenyl)acetic acid …
Pyridoxyl-Glutamic Acid-5'-Monophosphate
Experimental
Matched Name: … Pyridoxyl-Glutamic Acid-5'-Monophosphate …
2-Oxo-3-Pentenoic Acid
Experimental
Matched Name: … 2-Oxo-3-Pentenoic Acid …
Matched Iupac: … (3Z)-2-oxopent-3-enoic acid …
Matched Iupac: … (3Z)-2-oxopent-3-enoic acid …
6-phospho-D-gluconic acid
Experimental
Matched Name: … 6-phospho-D-gluconic acid …
Matched Iupac: … (2R,3S,4R,5R)-2,3,4,5-tetrahydroxy-6-(phosphonooxy)hexanoic acid …
Matched Categories: … Sugar Acids ... Acids, Acyclic ... Hydroxy Acids ... Carboxylic Acids …
Matched Iupac: … (2R,3S,4R,5R)-2,3,4,5-tetrahydroxy-6-(phosphonooxy)hexanoic acid …
Matched Categories: … Sugar Acids ... Acids, Acyclic ... Hydroxy Acids ... Carboxylic Acids …
4-iodo-acetamido phenylboronic acid
Experimental
Matched Name: … 4-iodo-acetamido phenylboronic acid …
Matched Iupac: … [3-(2-iodoacetamido)phenyl]boronic acid …
Matched Iupac: … [3-(2-iodoacetamido)phenyl]boronic acid …
Displaying drugs 1501 - 1525 of 2560 in total