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Displaying drugs 1526 - 1550 of 1780 in total
MK-4541 is a 4-azasteroid and a selective androgen receptor modulator (SARM). MK-4541 acts as a dual selective SARM and is both a potent androgen receptor antagonist and a 5α-reductase inhibitor.
Investigational
Matched Synonyms: … 9bS,11aS)-6,9a,11a-trimethyl-7-oxo-2,3,3a,3b,4,5,5a,9b,10,11-decahydro-1H-indeno[5,4-f]quinolin-1-yl]carbamate
Matched Description: … MK-4541 acts as a dual selective SARM and is both a potent androgen receptor antagonist and a 5α-reductase ... MK-4541 is a 4-azasteroid and a selective androgen receptor modulator (SARM). …
Angiotensin II is under investigation for the treatment of Sepsis, Septic Shock, Diabetes Mellitus, and Acute Renal Failure. Angiotensin II has been investigated for the treatment, basic science, and diagnostic of Hypertension, Renin Angiotensin System, and Idiopathic Membranous Nephropathy. As of December 21, 2017 the FDA approved La Jolla Pharmaceutical's...
Approved
Investigational
Matched Synonyms: … Human angiotensin II ... Angiotensin II (human) …
Matched Description: … The novelty of the medication lies in the fact that it is the first and only use of synthetic human angiotensin ... Angiotensin II is under investigation for the treatment of Sepsis, Septic Shock, Diabetes Mellitus, and ... , Renin Angiotensin System, and Idiopathic Membranous Nephropathy. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Gatipotuzumab is under investigation in clinical trial NCT01899599 (Pankomab-gex™ Versus Placebo as Maintenance Therapy in Advanced Ovarian Cancer).
Investigational
Matched Synonyms: … with human-mus musculus monoclonal pankomab-gex light chain, dimer ... Immunoglobulin g1, anti-(mucin muc1) (human-mus musculus monoclonal pankomab-gex heavy chain), disulfide …
Empegfilgrastim is under investigation in clinical trial NCT01569087 (Dose-finding Study of Empegfilgrastim for Neutropenia Prophylaxis in Patients With Breast Cancer).
Investigational
Matched Synonyms: … Colony-stimulating factor, granulocyte (synthetic human), 30-kilodalton pegylated …
Matched Description: … trial NCT01569087 (Dose-finding Study of Empegfilgrastim for Neutropenia Prophylaxis in Patients With Breast
Matched Categories: … Antineoplastic and Immunomodulating Agents …
CAN-106 a novel, long-acting monoclonal antibody directed against human complement C5.
Investigational
Matched Synonyms: … disulfide with human monoclonal CAN106 Kappa-chain, dimer ... Immunoglobulin G [27-histidine,57-histidine,253-tyrosine,255- threonine,257-glutamic acid], anti-(human ... complement C5) (human monoclonal CAN106 hybrid y2-chain CH1-hinge region/y4-chain CH2- CH3 region), …
Matched Description: … CAN-106 a novel, long-acting monoclonal antibody directed against human complement C5. …
Epimedium grandiflorum top is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Synonyms: … Epimedium Grandiflorum Leaf/stem …
Rabbit anti-thymocyte globulin. Thymoglobulin is a polyclonal antibody that suppresses certain types of immune cells responsible for acute organ rejection in transplant patients. Thymoglobulin is a mixture of antibodies intended to bind to various cell surface antigens. The most common mode of action of Thymoglobulin is via selective depletion of...
Approved
Matched Synonyms: … Rabbit anti-human thymocyte globulin ... Anti-human thymocyte immunoglobulin, rabbit ... Rabbit anti-human thymocyte immunoglobulin …
Matched Description: … Thymoglobulin is a polyclonal antibody that suppresses certain types of immune cells responsible for ... The most common mode of action of Thymoglobulin is via selective depletion of T-cells. ... Thymoglobulin is a mixture of antibodies intended to bind to various cell surface antigens. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Fluids and Secretions ... Antineoplastic and Immunomodulating Agents ... Antibody-Surface Protein Interactions …
Investigational
Matched Synonyms: … Autologous CD34+ cells transduced ex vivo with a lentiviral vector (Chim-CD18-WPRE) encoding the ITGB2 ... Hematopoietic stem cells modified with a lentiviral vector containing the CD18 (integrin beta 2) gene …
Investigational
Matched Synonyms: … Human recombinant factor VIIa variant (P10Q, K32E, T106N, V253N), desialylated …
Satralizumab is a recombinant humanized monoclonal antibody targeted against human interleukin-6 (IL-6) receptors, similar to tocilizumab, which is produced in Chinese hamster ovary cells and based on an IgG2 framework. Satralizumab is used in the treatment of neuromyelitis optica spectrum disorder (NMOSD), a rare autoimmune inflammatory disorder of the central...
Approved
Matched Synonyms: … Humanised anti-IL-6 receptor monoclonal antibody
Matched Description: … 6) receptors, similar to [tocilizumab], which is produced in Chinese hamster ovary cells and based on ... Satralizumab is a recombinant humanized monoclonal antibody targeted against human interleukin-6 (IL- ... [A218551] Some of the pro-inflammatory mechanisms involved in NMOSD are thought to be mediated, at least
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
A166 is an antibody-drug conjugate composed of a novel cytotoxic drug (Duo-5, anti-microtubule agent) site-specifically conjugated to an anti-HER2 antibody (trastuzumab) via a stable protease-cleavable valine citrulline linker.
Investigational
Matched Synonyms: … Recombinant humanized IgG1 anti-HER2 monoclonal antibody conjugated to Duostatin-5 …
Matched Description: … A166 is an antibody-drug conjugate composed of a novel cytotoxic drug (Duo-5, anti-microtubule agent) ... site-specifically conjugated to an anti-HER2 antibody (trastuzumab) via a stable protease-cleavable …
Tenoxicam, an antiinflammatory agent with analgesic and antipyretic properties, is used to treat osteoarthritis and control acute pain.
Approved
Matched Description: … and control acute pain. ... Tenoxicam, an antiinflammatory agent with analgesic and antipyretic properties, is used to treat osteoarthritis …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … BART
Investigational
Matched Name: … Allogeneic human pancreatic islets of Langerhans …
Risedronic acid is a third generation bisphosphonate that is used for the treatment of some forms of osteoperosis and Paget's disease[FDA Label][A959,A203111]. It functions by preventing resorption of bone[FDA Label] .
Approved
Investigational
Matched Description: … acid is a third generation bisphosphonate that is used for the treatment of some forms of osteoperosis and
Matched Mixtures name: … Actonel With Calcium ... Actonel With Calcium ... Actonel with Calcium
Matched Categories: … Calcium-Regulating Hormones and Agents ... risedronic acid and calcium, sequential ... risedronic acid, calcium and colecalciferol, sequential ... Drugs Affecting Bone Structure and Mineralization ... risedronic acid and colecalciferol …
Matched Products: … ACTONEL PLUS CALCIUM 35MG …
Parathyroid Hormone-Related Protein 1-36 is under investigation in clinical trial NCT00853723 (Comparison Study of Pthrp and PTH to Treat Osteoporosis).
Investigational
Matched Synonyms: … 1-36 human humoral hypercalcemic factor ... Parathormone-related peptide (1-36) (human) ... 1-36 human parathyroid hormone-related protein …
Matched Description: … Hormone-Related Protein 1-36 is under investigation in clinical trial NCT00853723 (Comparison Study of Pthrp and
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Intercellular Signaling Peptides and Proteins …
Ocimum tenuiflorum top is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Matched Synonyms: … Holy Basil Leaf/stem …
Experimental
Matched Synonyms: … Thin-leaf polygala root …
Investigational
Matched Synonyms: … 1-193-BACTERICIDAL/PERMEABILITY-INCREASING PROTEIN (132-ALANINE) (HUMAN) ... 1-193-BACTERICIDAL/PERMEABILITY-INCREASING PROTEIN (132-ALANINE) (HUMAN REDUCED) …
Dilpacimab is under investigation in clinical trial NCT03368859 (A Study of ABT-165 Plus FOLFIRI vs Bevacizumab Plus FOLFIRI in Subjects With Metastatic Colorectal Cancer Previously Treated With Fluoropyrimidine, Oxaliplatin and Bevacizumab).
Investigational
Matched Synonyms: … heavy chain), disulfide with synthetic human pr-1283233 light chain, dimer ... Immunoglobulin, anti-(notch ligand dll4/vascular endothelial growth factor) (synthetic human pr-1283233 …
Matched Description: … in Subjects With Metastatic Colorectal Cancer Previously Treated With Fluoropyrimidine, Oxaliplatin and
Matched Categories: … Amino Acids, Peptides, and Proteins …
Cabergoline, an ergot derivative, is a long-acting dopamine agonist and prolactin inhibitor. It is used to treat hyperprolactinemic disorders and Parkinsonian Syndrome. Cabergoline possesses potent agonist activity on dopamine D2 receptors.
Approved
Matched Description: … Cabergoline, an ergot derivative, is a long-acting dopamine agonist and prolactin inhibitor. ... It is used to treat hyperprolactinemic disorders and Parkinsonian Syndrome. …
Matched Categories: … Ergot Alkaloids and Derivatives ... Genito Urinary System and Sex Hormones …
Matched Products: … SHELDY
SBT-100 is an anti-signal transducer and activator of transcription 3 (STAT3) B VHH13 single-domain antibody (sdAb). It was granted orphan drug designation by the FDA for the treatment of pancreatic cancer and osteosarcoma.[L44131,L44136]
Investigational
Matched Synonyms: … Anti-STAT3 B VHH13 single domain antibody
Matched Description: … SBT-100 is an anti-signal transducer and activator of transcription 3 (STAT3) B VHH13 single-domain antibody ... It was granted orphan drug designation by the FDA for the treatment of pancreatic cancer and osteosarcoma …
Approved
Investigational
Matched Products: … Humco Aluminum Acetate Burrow …
Investigational
Matched Synonyms: … Human recombinant histidyl-t-RNA synthetase (residues 2-506) …
INVAC-1 is under investigation in clinical trial NCT03265717 (DNA Plasmid Encoding a Modified Human Telomerase Reverse Transcriptase (Htert), Invac-1 in Chronic Lymphocytic Leukemia).
Investigational
Matched Synonyms: … Human telomerase reverse transcriptase (htert) dna vaccine invac-1 ... Invac-1, a double stranded dna plasmid vaccine construct encoding ubiquitin-human telomerase reverse …
Matched Description: … INVAC-1 is under investigation in clinical trial NCT03265717 (DNA Plasmid Encoding a Modified Human Telomerase …
Efruxifermin is under investigation in clinical trial NCT06215716 (A Study Evaluating Efruxifermin in Subjects With Non-cirrhotic Nonalcoholic Steatohepatitis (Nash)/metabolic Dysfunction-associated Steatohepatitis (MASH) and Fibrosis).
Investigational
Matched Synonyms: … factor 21 (98-arginine,171-glycine,180-glutamic acid) (human mutant clone amg876) ... Immunoglobulin g (synthetic human constant domain fc fragment) fusion protein with fibroblast growth ... Immunoglobulin g1 (human .gamma.1-chain c-region c-terminal fragment) fusion protein with peptide linker …
Matched Description: … Non-cirrhotic Nonalcoholic Steatohepatitis (Nash)/metabolic Dysfunction-associated Steatohepatitis (MASH) and
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Displaying drugs 1526 - 1550 of 1780 in total