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Displaying drugs 1551 - 1575 of 1920 in total

Oxcarbazepine

Oxcarbazepine is an anti-epileptic medication used in the treatment of partial onset seizures that was first approved for use in the United States in 2000.[L8627,L8630,L8633] It is a structural derivative of carbamazepine and exerts a majority of its activity via a pharmacologically active metabolite, MHD, which exists as a racemate...
Approved
Matched Description: … [L8627,L8630,L8633] It is a structural derivative of [carbamazepine][A186101] and exerts a majority of …
Matched Categories: … Metabolic Side Effects of Drugs and Substances ... Sodium Channel Blockers ... Voltage-Gated Sodium Channel Blockers …
Matched Products: … OXCARIL 150 MG FILM TABLET, 50 ADET ... OXCARIL 300 MG FILM TABLET, 50 ADET ... OXCARIL 600 MG FILM TABLET, 50 ADET …

Ertugliflozin

Ertugliflozin is a sodium-dependent glucose cotransporter-2 (SGLT2) inhibitor used to treat type II diabetes mellitus. It works to block glucose reabsorption from the glomerulus. Ertugliflozin was first approved by the FDA in December 2017.[A261951, L1132] It was also approved by the European Commission in March 2018.
Approved
Investigational
Matched Description: … Ertugliflozin is a sodium-dependent glucose cotransporter-2 (SGLT2) inhibitor used to treat type II diabetes …
Matched Mixtures name: … Steglujan (Ertugliflozin 5mg/Sitagliptin 100mg) Film-Coated Tablets ... Steglujan (Ertugliflozin 15mg/Sitagliptin 100mg) Film-Coated Tablets ... Segluromet (Ertugliflozin 2.5mg/ Metformin 500mg) Film-Coated Tablet …
Matched Categories: … Alimentary Tract and Metabolism ... metformin and ertugliflozin ... sitagliptin and ertugliflozin ... Sodium-Glucose Transporter 2 Inhibitors ... Sodium-glucose Cotransporter 2 (SGLT2) Inhibitors …
Matched Products: … STEGLATRO FILM-COATED TABLETS 5MG ... Steglatro 5mg Film-Coated Tablets ... STEGLATRO FILM-COATED TABLETS 15MG …

Mirabegron

Mirabegron is a sympathomimetic beta-3 adrenergic receptor agonist used to relax the smooth muscle of the bladder in the treatment of urinary frequency and incontinence. It is unique amongst overactive bladder treatment options in that, unlike other treatments such as solifenacin and darifenacin, it lacks significant antimuscarinic activity, which is...
Approved
Matched Description: … receptor agonist used to relax the smooth muscle of the bladder in the treatment of urinary frequency and ... amongst overactive bladder treatment options in that, unlike other treatments such as [solifenacin] and ... antimuscarinic activity,[A232553] which is responsible both for the therapeutic effects of these medications and …
Matched Categories: … Genito Urinary System and Sex Hormones ... Drugs for Urinary Frequency and Incontinence ... Sulfur Compounds …
Matched Products: … BETMIGA 25 MG UZATILMIŞ SALIMLI FILM TABLET , 10 TABLET ... BETMIGA 25 MG UZATILMIŞ SALIMLI FILM TABLET , 100 TABLET ... BETMIGA 25 MG UZATILMIŞ SALIMLI FILM TABLET , 50 TABLET …

Empagliflozin

Empagliflozin is an inhibitor of sodium-glucose co-transporter-2 (SGLT2), the transporters primarily responsible for the reabsorption of glucose in the kidney. It is used clinically as an adjunct to diet and exercise, often in combination with other drug therapies,[L13673,L13679,L11479] for the management of type 2 diabetes mellitus. The first known inhibitor...
Approved
Matched Description: … Empagliflozin is an inhibitor of sodium-glucose co-transporter-2 (SGLT2), the transporters primarily ... [L13688] The first known inhibitor of SGLTs, phlorizin, was isolated from the bark of apple trees ... led to the FDA approval of [canagliflozin] in 2013 and both [dapagliflozin] and empagliflozin in 2014 …
Matched Mixtures name: … Glyxambi Film-Coated Tablets 25mg/5mg ... Glyxambi Film-Coated Tablets 10mg/5mg ... GLYXAMBI FILM-COATED TABLETS 25 MG/5 MG …
Matched Categories: … Alimentary Tract and Metabolism ... metformin and empagliflozin ... linagliptin and empagliflozin ... metformin, linagliptin and empagliflozin ... Sodium-Glucose Transporter 2 Inhibitors …
Matched Products: … JARDIANCE FILM-COATED TABLETS 10MG ... JARDIANCE FILM-COATED TABLET 25MG ... Jardiance 10mg film coated tablets …

Bosentan

Bosentan is a dual endothelin receptor antagonist marketed under the trade name Tracleer by Actelion Pharmaceuticals. Bosentan is used to treat pulmonary hypertension by blocking the action of endothelin molecules that would otherwise promote narrowing of the blood vessels and lead to high blood pressure.
Approved
Investigational
Matched Description: … blocking the action of endothelin molecules that would otherwise promote narrowing of the blood vessels and …
Matched Categories: … Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics ... Sulfur Compounds …
Matched Products: … PROART FILM COATED TABLETS 125MG ... CLOKSAR 125 MG FILM TABLET, 56 TABLET ... DIAMOND 125 MG FILM TABLET, 112 ADET …

Zofenopril

Zofenopril is employed as both a cardioprotective and anti-hypertensive agent. It is an angiotensin-converting enzyme (ACE) inhibitor.
Approved
Matched Description: … Zofenopril is employed as both a cardioprotective and anti-hypertensive agent. …
Matched Mixtures name: … BIFRIL PLUS 30/12.5 MG FILM TABLET, 28 ADET ... BIFRIL PLUS 30/12.5 MG FILM TABLET, 84 ADET ... ZOPROTEC PLUS 30/12.5 MG FILM TABLET, 28 ADET …
Matched Salts name: … Zofenopril calcium …
Matched Categories: … Amino Acids, Peptides, and Proteins ... ACE Inhibitors and Diuretics ... Protease Inhibitors ... zofenopril and diuretics ... zofenopril and nebivolol …
Matched Products: … BIFRIL 15 MG (FILM-COATED TABLETS) ... BIFRIL 30 MG (FILM-COATED TABLETS) ... BIFRIL 30 MG FILM TABLET, 14 ADET …

Sitagliptin

Sitagliptin is an oral dipeptidyl peptidase-4 (DPP-4) inhibitor used in conjunction with diet and exercise to improve glycemic control in patients with type 2 diabetes mellitus[FDA label,A2260,A2255,A2256]. The effect of this medication leads to glucose dependent increases in insulin and decreases in glucagon to improve control of blood sugar[FDA label,A2255]....
Approved
Investigational
Matched Description: … Sitagliptin is an oral dipeptidyl peptidase-4 (DPP-4) inhibitor used in conjunction with diet and exercise ... The effect of this medication leads to glucose dependent increases in insulin and decreases in glucagon …
Matched Mixtures name: … Reddy-sitagliptin and Metformin Hydrochloride ... Reddy-sitagliptin and Metformin Hydrochloride ... Reddy-sitagliptin and Metformin Hydrochloride …
Matched Salts name: … Sitagliptin phosphate …
Matched Categories: … Protease Inhibitors ... Alimentary Tract and Metabolism ... metformin and sitagliptin ... sitagliptin and simvastatin ... sitagliptin and ertugliflozin …
Matched Products: … PTİAGLİN 100 MG FİLM KAPLI TABLET ... İVOBRA 5 MG FİLM KAPLI TABLET, 56 ADET ... Sitavia Film Coated Tablet 100mg …

Memantine

Initially approved by the FDA in 2013, memantine is an N-methyl-D-aspartate (NMDA) receptor antagonist used in the management of Alzheimer's Disease (AD). It is different from many other Alzheimer's Disease medications, as it works by a different mechanism than the cholinesterase enzyme inhibitors normally employed in the management of Alzheimer's...
Approved
Investigational
Matched Description: … blocks the effects of glutamate, a neurotransmitter in the brain that leads to neuronal excitability and ... doubling every 20 years, the prevalence of Alzheimer's Disease is predicted to reach 66 million by 2030 and …
Matched Mixtures name: … Memantine and Donepezil Hydrochlorides Extended-release ... Memantine and Donepezil Hydrochlorides Extended-release ... Memantine and Donepezil Hydrochlorides Extended-release …
Matched Categories: … donepezil and memantine ... donepezil, memantine and Ginkgo folium …
Matched Products: … MENTAX 10 MG FILM TABLET,FILM TABLET, 100 ADET ... AXURA 5/10/15/20MG FILM ST ... ALMENTA 15MG FILM TABLET, 28 ADET …

Endostar

Endostar is under investigation for the treatment of Nasopharyngeal Carcinoma. Endostar has been investigated for the treatment of Non-small Cell Lung Cancer.
Investigational
Matched Synonyms: … Recombinant human endostatin protein …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins ... Proteins ... Angiogenic Proteins ... Angiostatic Proteins …

OMS906

OMS906 is a humanized Igg4 monoclonal antibody against mannan-binding lectin-associated serine protease-3 (MASP-3) currently being developed by Omeros.
Investigational
Matched Synonyms: … -3 (MASP-3) ... Humanized immunoglobulin G4 monoclonal antibody directed against mannan-binding lectin-associated serine protease …
Matched Description: … -3 (MASP-3) currently being developed by Omeros. ... OMS906 is a humanized Igg4 monoclonal antibody against mannan-binding lectin-associated serine protease …

Olaparib

Olaparib is a selective and potent inhibitor of poly (ADP-ribose) polymerase (PARP) enzymes, PARP1 and PARP2.[L41100, L40908, L43792] PARP inhibitors represent a novel class of anti-cancer therapy and they work by taking advantage of a defect in DNA repair in cancer cells with BRCA mutations and inducing cell death. Olaparib...
Approved
Matched Description: … Olaparib is a selective and potent inhibitor of poly (ADP-ribose) polymerase (PARP) enzymes, PARP1 and ... [L41100, L40908, L43792] It was first approved by the FDA and EU in December 2014,[A246020] and by Health ... [L41100, L40908, L43792] PARP inhibitors represent a novel class of anti-cancer therapy and they work …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … LYNPARZA FILM-COATED TABLET 150MG ... LYNPARZA FILM-COATED TABLET 100MG ... Lynparza 150 mg Film-Coated Tablets …

Finerenone

Finerenone, or BAY 94-8862, is a mineralocorticoid receptor antagonist indicated to reduce the risk of sustained decline in glomerular filtration rate, end stage kidney disease, cardiovascular death, heart attacks, and hospitalization due to heart failure in adults with chronic kidney disease associated with type II diabetes mellitus.[A236519,L34739] Patients with kidney...
Approved
Investigational
Matched Description: … [A236544] Spironolactone has low selectivity and affinity for the receptor; it dissociates quickly and ... decline in glomerular filtration rate, end stage kidney disease, cardiovascular death, heart attacks, and ... [A236544] Eplerenone is more selective and has longer lasting effects. …
Matched Products: … KERENDIA FILM-COATED TABLET 10MG ... KERENDIA FILM-COATED TABLET 20MG ... KERENDİA 10 MG FİLM KAPLI TABLET, 98 ADET …

Prucalopride

Prucalopride is a dihydrobenzofurancarboxamide derivative from the benzofurane family that selectively stimulates 5-HT4 receptors and thus, it presents enterokinetic properties. The high selectivity of prucalopride allowed further development as it prevented the cardiac adverse reactions observed due to non-target effects of precedent therapies. Prucalopride was developed by Shire Development LLC...
Approved
Matched Description: … dihydrobenzofurancarboxamide derivative from the benzofurane family that selectively stimulates 5-HT4 receptors and ... A40250] in Canada on December 7, 2011 and by the FDA on December 17, 2018. ... [A40254] Prucalopride was developed by Shire Development LLC and approved for use in Europe in 2009,[ …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … Resolor Film-coated Tablet 2 mg ... Resolor Film-coated Tablet 1 mg ... RESOLOR 1mg Film Coated Tablets …

Fosfomycin

Fosfomycin was discovered in 1969 by scientists at the Spanish Penicillin and Antibiotics Company and is produced by Streptomyces fradiae.[A229338,A230348] It may also be produced synthetically and is commercially available as the disodium salt for intravenous administration and as the calcium or trometamol salt for oral administration. In terms of...
Approved
Matched Description: … salt for intravenous administration and as the calcium or trometamol salt for oral administration. ... Fosfomycin was discovered in 1969 by scientists at the Spanish Penicillin and Antibiotics Company and ... group and an epoxide ring. …
Matched Salts name: … Fosfomycin sodium ... Fosfomycin calcium monohydrate …
Matched Products: … FOSFOMYCIN SODIUM …

Rivaroxaban

Rivaroxaban is an anticoagulant and the first orally active direct factor Xa inhibitor. Unlike warfarin, routine lab monitoring of INR is not necessary. However there is no antidote available in the event of a major bleed. Only the 10 mg tablet can be taken without regard to food. The 15...
Approved
Matched Description: … Rivaroxaban is an anticoagulant and the first orally active direct factor Xa inhibitor. ... The 15 mg and 20 mg tablet should be taken with food. FDA approved on July 1, 2011. …
Matched Categories: … Blood and Blood Forming Organs ... rivaroxaban and acetylsalicylic acid ... Sulfur Compounds ... Protease Inhibitors ... Serine Protease Inhibitors …
Matched Products: … Xarelto 2.5mg Film-Coated Tablets ... Rivax 10mg Film Coated Tablets ... Rivax 20mg Film Coated Tablets …

Insulin human

Human Insulin, also known as Regular Insulin, is a short-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes. Human insulin is produced by recombinant DNA technology and is identical to endogenously produced insulin. Typically prescribed for the management of diabetes mellitus,...
Approved
Investigational
Matched Description: … Insulin also inhibits hepatic glucose production, enhances protein synthesis, and inhibits lipolysis ... Insulin, is a short-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and ... and proteolysis among many other functions. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Alimentary Tract and Metabolism ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Insulins and Analogues for Injection, Fast-Acting …
Matched Products: … Actrapid® FlexPen® 100 IU/ml Solution for Injection in Pre-filled Pen ... Mixtard® 30 FlexPen® 100 IU/ml Suspension for Injection in Pre-filled Pen …

Benidipine

Benidipine has the formula 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridine-dicarboxylic acid methyl 1-(phenylmethyl)-3-piperidinyl ester hydrochloride. It is a synthetic dihydropyridine derivative that has anti-hypertensive and anti-anginal actions. It was originated in Japan by Kyowa Hakko, it is submitted for FDA approval and it is currently available in some Asian countries like India and Japan.[L1385, L1386]
Experimental
Matched Description: … available in some Asian countries like India and Japan. ... It is a synthetic dihydropyridine derivative that has anti-hypertensive and anti-anginal actions. ... [A31948] It was originated in Japan by Kyowa Hakko, it is submitted for FDA approval and it is currently …
Matched Categories: … Calcium-Regulating Hormones and Agents ... Calcium Channel Blockers ... Selective Calcium Channel Blockers With Mainly Vascular Effects …
Matched Products: … BENIPIN 4 MG FILM TABLET,TABLET, 30 ADET ... BENIPIN 8 MG FILM TABLET,TABLET, 30 ADET ... BENİTİDE 4 MG FİLM KAPLI TABLET, 30 ADET …

Abrocitinib

Abrocitinib is an oral small-molecule inhibitor of Janus kinase 1 (JAK1). Janus kinases are intracellular enzymes involved in transduction pathways that regulate hematopoiesis and immune cell function. The Janus kinase (JAK)–signal transducer and activator of transcription (STAT) signalling pathway plays a central role in the pathogenesis of a variety of...
Approved
Investigational
Matched Description: … Janus kinases are intracellular enzymes involved in transduction pathways that regulate hematopoiesis and ... [L39774] The Janus kinase (JAK)–signal transducer and activator of transcription (STAT) signalling pathway ... plays a central role in the pathogenesis of a variety of autoimmune and inflammatory diseases, including …
Matched Categories: … Sulfur Compounds ... Protein Kinase Inhibitors …
Matched Products: … Cibinqo 50mg Film-Coated Tablets ... Cibinqo 100mg Film-Coated Tablets ... Cibinqo 200mg Film-Coated Tablets …

Gefitinib

Gefitinib (originally coded ZD1839) is a drug used in the treatment of certain types of cancer. Acting in a similar manner to erlotinib (marketed as Tarceva), gefitinib selectively targets the mutant proteins in malignant cells. It is marketed by AstraZeneca under the trade name Iressa.
Approved
Investigational
Matched Description: … Acting in a similar manner to erlotinib (marketed as Tarceva), gefitinib selectively targets the mutant proteins …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Protein Kinase Inhibitors …
Matched Products: … VEIASU FILM-COATED TABLETS 250 MG ... Iressa 250mg Film-coated Tablet ... GEFTINAT FILM COATED TABLETS 250 MG …

Cefprozil

Cefprozil is a cephalosporin antibiotic that is commonly employed to treat a variety of bacterial infections, including those of the ear and skin, bronchitis, and others.
Approved
Matched Description: … skin, bronchitis, and others. ... antibiotic that is commonly employed to treat a variety of bacterial infections, including those of the ear and …
Matched Categories: … Sulfur Compounds …
Matched Products: … PREFIX 250 MG FILM TABLET, 10 ADET ... PREFIX 250 MG FILM TABLET, 14 ADET ... PREFIX 250 MG FILM TABLET, 20 ADET …

Dicloxacillin

One of the penicillins which is resistant to penicillinase.
Approved
Investigational
Vet approved
Matched Salts name: … Dicloxacillin sodium ... Dicloxacillin sodium anhydrous …
Matched Categories: … Sulfur Compounds …
Matched Products: … Dicloxacillin Sodium …

Lornoxicam

Lornoxicam (chlortenoxicam) is a new nonsteroidal anti-inflammatory drug (NSAID) of the oxicam class with analgesic, anti-inflammatory and antipyretic properties. Lornoxicam differs from other oxicam compounds in its potent inhibition of prostaglandin biosynthesis, a property that explains the particularly pronounced efficacy of the drug. Lornoxicam is approved for use in Japan.
Approved
Investigational
Matched Description: … new nonsteroidal anti-inflammatory drug (NSAID) of the oxicam class with analgesic, anti-inflammatory and …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Sulfur Compounds …
Matched Products: … XEFO 4 MG FILM KAPLI TABLET, 20 ADET ... XEFO RAPID 8 MG FILM KAPLI TABLET ... XEFO 8 MG FILM KAPLI TABLET, 20 ADET …

Ebastine

Ebastine is under investigation for the treatment of Irritable Bowel Syndrome (IBS). Ebastine has been investigated for the treatment of Urticaria.
Approved
Investigational
Matched Products: … EBAFIT 10 MG FILM KAPLI TABLET, 10 ADET ... KESTINE FILM-COATED TABLET 20MG ... EBAFIT 10 MG FILM KAPLI TABLET, 30 ADET …

Cefditoren

Cefditoren is an oral third-generation cephalosporin. It is commonly marketed under the trade name Spectracef by Cornerstone BioPharma.
Approved
Investigational
Matched Categories: … Sulfur Compounds …
Matched Products: … CEFITEN 200 MG FILM TABLET, 10 ADET ... CEFITEN 400 MG FILM TABLET, 14 ADET ... CEFITEN 400 MG FILM TABLET, 20 ADET …

Axitinib

Axitinib is a second generation tyrosine kinase inhibitor that works by selectively inhibiting vascular endothelial growth factor receptors (VEGFR-1, VEGFR-2, VEGFR-3). Through this mechanism of action, axitinib blocks angiogenesis, tumour growth and metastases. It is reported to exhibit potency that is 50-450 times higher than that of the first generation...
Approved
Investigational
Matched Description: … [L6676] Through this mechanism of action, axitinib blocks angiogenesis, tumour growth and metastases. ... [A179398] It is most commonly marketed under the name Inlyta® and is available in oral formulations. …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Benzamides and benzamide derivatives ... Protein Kinase Inhibitors …
Matched Products: … Inlyta Film-coated Tablets 1mg ... Inlyta Film-coated Tablets 5mg ... INLYTA 3 MG FİLM KAPLI TABLET, 28 ADET …
Displaying drugs 1551 - 1575 of 1920 in total