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Displaying drugs 1576 - 1600 of 1789 in total

Rofecoxib

Rofecoxib is used for the treatment of osteoarthritis, rheumatoid arthritis, acute pain in adults, and primary dysmenorrhea, as well as acute treatment of migraine attacks with or without auras. Rofecoxib is a solid. This compound belongs to the stilbenes. These are organic compounds containing a 1,2-diphenylethylene moiety. Stilbenes (C6-C2-C6 )...
Approved
Investigational
Withdrawn
Matched Description: … Rofecoxib is used for the treatment of osteoarthritis, rheumatoid arthritis, acute pain in adults, and ... doses of 125, 25, and 50 mg is approximately 93%. ... The proteins that rofecoxib target include elastin and prostaglandin G/H synthase 2. …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … REOX 25 MG FORT TABLET, 14 ADET ... REOX 25 MG FORT TABLET, 28 ADET …

Dobutamine

A beta-1 agonist catecholamine that has cardiac stimulant action without evoking vasoconstriction or tachycardia. It is proposed as a cardiotonic after myocardial infarction or open heart surgery.
Approved
Matched Categories: … Adrenergic and Dopaminergic Agents …
Matched Products: … Pharmaniaga Dobutamine 12.5mg/mL Concentrate for Solution for Infusion ... INOTROP (Dobutamine HCl 25mg/ml Concentrate for Solution for Infusion) …

Mebrofenin

Approved
Experimental
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … Kit for the Preparation of Technetium Tc 99m Mebrofenin …

Aminolevulinic acid

A compound produced from succinyl-CoA and glycine as an intermediate in heme synthesis. It is used as a photochemotherapy for actinic keratosis. [PubChem]
Approved
Matched Description: … A compound produced from succinyl-CoA and glycine as an intermediate in heme synthesis. ... It is used as a photochemotherapy for actinic keratosis. [PubChem] …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Skin and Mucous Membrane Agents ... Photosensitizing Agents for Phototherapy …
Matched Products: … GLIOLAN, POWDER FOR ORAL SOLUTION, 30 MG/ML …

Palonosetron

Palonosetron (INN, trade name Aloxi) is an antagonist of 5-HT3 receptors that is indicated for the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). It is the most effective of the 5-HT3 antagonists in controlling delayed CINV nausea and vomiting that appear more than 24 hours after the first...
Approved
Investigational
Matched Description: … and treatment of chemotherapy-induced nausea and vomiting (CINV). ... Food and Drug Administration. ... class approved for this use by the U.S. …
Matched Categories: … Alimentary Tract and Metabolism ... Antiemetics and Antinauseants …
Matched Products: … Solution for Injection 50mcg/ml ... ALOXI Solution for Injection 50mcg/ml ... Valentron 0.25mg/5ml Solution for Injection …

Flumazenil

Fumazenil is an imidazobenzodiazepine derivative and a potent benzodiazepine receptor antagonist that competitively inhibits the activity at the benzodiazepine recognition site on the GABA/benzodiazepine receptor complex, thereby reversing the effects of benzodiazepine on the central nervous system.
Approved
Matched Description: … Fumazenil is an imidazobenzodiazepine derivative and a potent benzodiazepine receptor antagonist that …
Matched Products: … Flumazenil Kabi 0.1 mg/mL Solution for Injection ... FLUMAZENIL-BAXTER SOLUTION FOR INJECTION 1 MG/10 ML ... FLUMAZENIL-BAXTER SOLUTION FOR INJECTION 0.5 MG/5 ML …

Lenograstim

Lenograstim is a recombinant granulocyte colony-stimulating factor used as an immunostimulating agent.
Approved
Investigational
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins …
Matched Products: … GRANOCYTE 34 FOR INJECTION 263 mcg/ml …

Amiodarone

Amiodarone is a benzofuran derivative, anti-arrhythmic drug used commonly in a variety of settings. Most known for its approved indication in life-threatening ventricular arrhythmias, it is also used off-label in the outpatient and inpatient setting for atrial fibrillation. Because of its ability to cause serious toxicity and possibly death, amiodarone...
Approved
Investigational
Matched Description: … used off-label in the outpatient and inpatient setting for atrial fibrillation. ... Because of its ability to cause serious toxicity and possibly death, amiodarone use should be reserved ... for its approved indications, according to prescribing information. …
Matched Categories: … Metabolic Side Effects of Drugs and Substances ... Calcium Channel Blockers ... Sodium Channel Blockers ... Potassium Channel Blockers ... Medications that reduce magnesium levels …
Matched Products: … DIOLUX CONCENTRATE FOR SOLUTION FOR INJECTION 50MG/ML ... Amiodarone for Injection 50mg/ml ... Amiodarone Hydrochloride for Injection …

Epirubicin

An anthracycline which is the 4'-epi-isomer of doxorubicin. The compound exerts its antitumor effects by interference with the synthesis and function of DNA.
Approved
Matched Description: … The compound exerts its antitumor effects by interference with the synthesis and function of DNA. …
Matched Categories: … Anthracyclines and Related Substances ... Antineoplastic and Immunomodulating Agents ... Cytotoxic Antibiotics and Related Substances …
Matched Products: … EPIROL Epirubicin Hydrochloride Powder for Solution for Injection 10mg ... EPIROL Epirubicin Hydrochloride Powder for Solution for Injection 50mg ... Epirubicin for Injection …

Coenzyme M

Coenzyme M (commonly known by its salt form, Mesna) is a synthetic sulfhydryl (thiol) compound and is used for prophylaxis of Ifosfamide and cyclophosphamide induced hemorrhagic cystitis.
Approved
Investigational
Matched Description: … used for prophylaxis of Ifosfamide and cyclophosphamide induced hemorrhagic cystitis. ... Coenzyme M (commonly known by its salt form, Mesna) is a synthetic sulfhydryl (thiol) compound and is …
Matched Mixtures name: … IFEX and MESNEX ... IFEX and MESNEX ... IFEX and MESNEX …
Matched Categories: … Cough and Cold Preparations ... Detoxifying Agents for Antineoplastic Treatment …
Matched Products: … Mesna for Injection ... CONCENTRATE SOLUTION FOR INJECTION 400MG/4ML …

Trabectedin

Trabectedin, also referred as ET-743 during its development, is a marine-derived antitumor agent discovered in the Carribean tunicate Ecteinascidia turbinata and now produced synthetically. Trabectedin has a unique mechanism of action. It binds to the minor groove of DNA interfering with cell division and genetic transcription processes and DNA repair...
Approved
Investigational
Matched Description: … It is approved for use in Europe, Russia and South Korea for the treatment of advanced soft tissue sarcoma ... and DNA repair machinery. ... and ovarian cancer. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … YONDELIS 1MG FOR INJECTION ... YONDELIS Powder for Injection 1mg/vial …

Benzoic acid

A fungistatic compound that is widely used as a food preservative. It is conjugated to GLYCINE in the liver and excreted as hippuric acid. As the sodium salt form, sodium benzoate is used as a treatment for urea cycle disorders due to its ability to bind amino acids. This leads...
Approved
Investigational
Matched Description: … As the sodium salt form, sodium benzoate is used as a treatment for urea cycle disorders due to its ability ... It is conjugated to GLYCINE in the liver and excreted as hippuric acid. ... This leads to excretion of these amino acids and a decrease in ammonia levels. …
Matched Mixtures name: … Sodium Phenylacetate and Sodium Benzoate ... Sodium Phenylacetate and Sodium Benzoate ... Sodium Phenylacetate and Sodium Benzoate …
Matched Salts name: … Calcium benzoate ... Sodium benzoate …
Matched Categories: … sodium benzoate and sodium phenylacetate ... caffeine and sodium benzoate ... Tests for Gastric Secretion ... Alimentary Tract and Metabolism ... sodium benzoate …
Matched Products: … S Panax Mist for Refill …

Rabies virus inactivated antigen, B

Inactivated rabies virus antigen B is a component of rabies vaccines used for pre- and post-exposure prophylaxis against rabies.
Approved
Matched Description: … Inactivated rabies virus antigen B is a component of rabies vaccines used for pre- and post-exposure …
Matched Categories: … Immune Sera and Immunoglobulins ... Antiinfectives for Systemic Use …
Matched Products: … RABIES VACCINE FOR HUMAN USE (VERO CELL), FREEZE-DRIED FINAL BULK …

Ioflupane I-123

Ioflupane (I-123) is a radiopharmaceutical used to image dopamine neurons and diagnose Parkinsonian syndromes.
Approved
Matched Description: … Ioflupane (I-123) is a radiopharmaceutical used to image dopamine neurons and diagnose Parkinsonian syndromes …
Matched Products: … DATSCAN SOLUTION FOR INJECTION 74 MBQ/ML …

Pyridoxal

The 4-carboxyaldehyde form of vitamin B 6 which is converted to pyridoxal phosphate which is a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. [PubChem]
Experimental
Nutraceutical
Matched Synonyms: … 2-methyl-3-hydroxy-4-formyl-5-hydroxymethylpyridine …
Matched Description: … The 4-carboxyaldehyde form of vitamin B 6 which is converted to pyridoxal phosphate which is a coenzyme ... for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic …

Pholcodine

Pholcodine formula is 3-o-morpholinoethylmorphine and it is classified as an antitussive which is defined as an opioid cough suppressant. It belongs to the opioid family of compounds and it is widely used. Pholcodine activity is the suppression of unproductive cough and it also has a mild sedative effect with little...
Approved
Illicit
Matched Description: … Pholcodine formula is 3-o-morpholinoethylmorphine and it is classified as an antitussive which is defined ... It belongs to the opioid family of compounds and it is widely used. ... [A31738] Pholcodine activity is the suppression of unproductive cough and it also has a mild sedative …
Matched Categories: … Cough and Cold Preparations ... Opium Alkaloids and Derivatives …
Matched Products: … Pholcodyl Forte Syrup ... Tussedyl Forte Syrup 15mg/5ml ... Ducodin Forte Linctus 15mg/5ml …

Temsirolimus

Temsirolimus is a derivative of sirolimus used in the treatment of renal cell carcinoma (RCC). It was developed by Wyeth Pharmaceuticals under the trade name Torisel. Temsirolimus was approved by the FDA in late May 2007 as well as the European Medicines Agency (EMEA) on November 2007.
Approved
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Sirolimus and Prodrugs …
Matched Products: … Torisel Concentrate for Injection 25mg/mL …

5-hydroxy-4-(7-methoxy-1,1-dioxido-2H-1,2,4-benzothiadiazin-3-yl)-2-(3-methylbutyl)-6-phenylpyridazin-3(2H)-one

Experimental
Matched Name: … 5-hydroxy-4-(7-methoxy-1,1-dioxido-2H-1,2,4-benzothiadiazin-3-yl)-2-(3-methylbutyl)-6-phenylpyridazin …

Cocoa butter

Cocoa butter is an edible natural fat obtained from the Theobroma cocoa seeds that is predominantly found in dark chocolate . It is a rich source of monounsaturated and saturated fatty acids that mainly contains approximately 33% DB04224, 25% DB03796, and 33% DB03193 but does not contain caffeine or theobromine....
Approved
Matched Description: … Still, it is a common active ingredient for prevention of skin dryness in cosmetic and skincare products ... Cocoa butter is included in chocolate and other food products, and can also be found in over-the-counter ... It is a rich source of monounsaturated and saturated fatty acids [A33040] that mainly contains approximately …
Matched Mixtures name: … Up and Up Hemorrhoidal …
Matched Categories: … Antipruritics and Local Anesthetics ... Diet, Food, and Nutrition …
Matched Products: … Dermatitica Synergy for treatment of Dermatitis …

Carmustine

A cell-cycle phase nonspecific alkylating antineoplastic agent. It is used in the treatment of brain tumors and various other malignant neoplasms. (From Martindale, The Extra Pharmacopoeia, 30th ed, p462) This substance may reasonably be anticipated to be a carcinogen according to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985)....
Approved
Investigational
Matched Description: … It is used in the treatment of brain tumors and various other malignant neoplasms. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … Carmustine for Injection USP ... BiCNU-100MG (CARMUSTINE FOR INJECTION USP 100MG) & DEHYDRATED ALCOHOL INJECTION USP AS A COMBIPACK …

Rocuronium

Rocuronium (rapid onset-curonium) is a desacetoxy analogue of vecuronium with a more rapid onset of action. It is an aminosteroid non-depolarizing neuromuscular blocker or muscle relaxant used in modern anaesthesia, to facilitate endotracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation. Introduced in 1994, rocuronium has...
Approved
Matched Description: … It is commonly marketed under the trade names Zemuron and Esmeron. ... Introduced in 1994, rocuronium has rapid onset, and intermediate duration of action. ... neuromuscular blocker or muscle relaxant used in modern anaesthesia, to facilitate endotracheal intubation and …
Matched Products: … Rocuronium Kabi 10mg/ml Solution for Injection/Infusion ... ROCURONIUM BROMIDE SOLUTION FOR INJECTION 10mg/ml ... Braun 10mg/ml Solution for Injection / Infusion …

Carbocisteine

Dyspnea and cough are common symptoms of chronic obstructive pulmonary disease (COPD) and other respiratory conditions characterized by increased mucus production. Individuals with COPD have a greater risk of pulmonary infection due to the growth and accumulation of viruses and bacteria in thick bronchial mucus. Carbocisteine is a mucolytic drug...
Approved
Investigational
Matched Description: … [L32383] Several licenses for this drug were withdrawn following serious and fatal paradoxical effects ... Dyspnea and cough are common symptoms of chronic obstructive pulmonary disease (COPD)[A231169] and other ... viruses and bacteria in thick bronchial mucus. …
Matched Mixtures name: … AXIM TOSTHERAPY FORTE® …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Cough and Cold Preparations …
Matched Products: … MUKO-S FORT 375 MG TABLET , 20 ADET ... MUKOTIK FORT 375 MG TABLET, 20 ADET ... MUKOTIK FORT 375 MG TABLET, 50 ADET …

Calfactant

Calfactant is a sterile, non-pyrogenic lung surfactant intended for intratracheal instillation. It is an off-white suspension of an extract of natural surfactant from calf lungs suspended in 0.9% saline. Each milliliter of calfactant contains 35mg of phospholipids (including 26 mg phosphatidylcholine of which 16 mg is disaturated phosphatidylcholine) and 0.65mg...
Approved
Matched Description: … 0.65mg of proteins including surfactant-associated proteins B and C. ... phospholipids (including 26 mg phosphatidylcholine of which 16 mg is disaturated phosphatidylcholine) and ... decrease the incidence of respiratory distress syndrome, mortality due to respiratory distress syndrome, and …
Matched Products: … BLES (bovine lipid extract surfactant) 27 mg/ml Suspension for Intratracheal Instillation …

Cetuximab

Cetuximab is a recombinant chimeric human/mouse IgG1 monoclonal antibody that competitively binds to epidermal growth factor receptor (EGFR) and competitively inhibits the binding of epidermal growth factor (EGF). EGFR is a member of the ErbB family of receptor tyrosine kinases found in both normal and tumour cells; it is responsible...
Approved
Matched Description: … cells; it is responsible for regulating epithelial tissue development and homeostasis. ... [A227963] Approved by the FDA in February 2004 under the brand name ERBITUX, cetuximab is used for ... the treatment of head and neck cancer and metastatic, KRAS wild-type colorectal cancer, and metastatic …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Matched Products: … ERBITUX 5MG/ML SOLUTION FOR INFUSION …

Aldesleukin

Aldesleukin, a lymphokine, is produced by recombinant DNA technology using a genetically engineered E. coli strain containing an analog of the human interleukin-2 gene. Genetic engineering techniques were used to modify the human IL-2 gene, and the resulting expression clone encodes a modified human interleukin-2. This recombinant form differs from...
Approved
Matched Description: … Genetic engineering techniques were used to modify the human IL-2 gene, and the resulting expression ... This recombinant form differs from native interleukin-2 in the following ways: a) Aldesleukin is not ... glycosylated because it is derived from E. coli; b) the molecule has no N-terminal alanine; the codon for …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins …
Matched Products: … PROLEUKIN POWDER FOR INFUSION 18 miu/vial …
Displaying drugs 1576 - 1600 of 1789 in total