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Displaying drugs 1576 - 1600 of 1946 in total
Pegfilgrastim is a PEGylated form of the recombinant human granulocyte colony-stimulating factor (G-CSF) analogue, filgrastim. The drug is approved for use to decrease the incidence of infection, as manifested by febrile neutropenia, in susceptible patients with with non-myeloid cancer receiving myelosuppressive anti-cancer treatment. Although the risk of developing febrile neutropenia...
Approved
Matched Description: … pharmacokinetic profile and conditions of use. ... than 20% in many readily used chemotherapy regimens,[A248855] infections pose risks of hospitalization and ... [A29,A187607] Due to a longer half-life and slower elimination rate than filgrastim, pegfilgrastim requires …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins …
Matched Products: … Pelgraz 6 mg solution for injection in a pre-filled syringe ... Pelgraz Solution for Injection in pre-filled syringe 6mg/0.6mL ... Filpegla 6 mg / 0.6 mL Solution for Injection in Pre-filled Syringe …
Streptokinase, is a sterile, purified preparation of a bacterial protein elaborated by group C (beta) -hemolytic streptococci.
Approved
Investigational
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Enzymes and Coenzymes …
Matched Products: … Streptokinase Karma 1 500 000 IU Powder for Solution for Infusion …
Pentetic acid, also known as diethylenetriaminepentaacetic acid (DTPA), is a synthetic polyamino carboxylic acid with eight coordinate bond forming sites that can sequester metal ions and form highly stable DTPA-metal ion complexes. DTPA, along with its calcium and zinc trisodium salts, are the only FDA approved agents for the treatment...
Approved
Matched Description: … acid with eight coordinate bond forming sites that can sequester metal ions and form highly stable DTPA-metal ... DTPA, along with its calcium and zinc trisodium salts, are the only FDA approved agents for the treatment ... [L2242] DPTA was developed by the pharmaceutical company CIS US and FDA approved on April 14, 2004. …
Matched Products: … TECHNESCAN DTPA FOR INJECTION 20.8 mg/vial ... Kit for the Preparation of Technetium Tc 99m Pentetate Injection …
Lanreotide is a drug employed in the management of acromegaly (a hormonal condition caused by excess growth hormone) in addition to symptoms caused by neuroendocrine tumors, especially carcinoid syndrome. This drug is a long-acting analog of the drug somatostatin, a growth hormone inhibitor. Lanreotide is manufactured by the company, Ipsen...
Approved
Matched Description: … Lanreotide is manufactured by the company, _Ipsen Pharmaceuticals_ as lanreotide acetate, and marketed ... It is approved in several countries worldwide, including the United Kingdom, Australia, and Canada. ... Lanreotide was first approved for use in the United States by the FDA on August 30, 2007. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Pituitary and Hypothalamic Hormones and Analogues ... Somatostatin and Analogues ... Sex Hormones and Insulins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Somatuline Autogel 120mg, prolonged-release solution for injection in a pre-filled syringe ... Somatuline Autogel 60mg, prolonged-release solution for injection in a pre-filled syringe ... Somatuline Autogel 90mg, prolonged-release solution for injection in a pre-filled syringe …
Voriconazole (Vfend, Pfizer) is a triazole antifungal medication used to treat serious fungal infections. It is used to treat invasive fungal infections that are generally seen in patients who are immunocompromised. These include invasive candidiasis, invasive aspergillosis, and emerging fungal infections. The increased affinity of voriconazole for 14-alpha sterol demethylase...
Approved
Matched Description: … These include invasive candidiasis, invasive aspergillosis, and emerging fungal infections. ... The increased affinity of voriconazole for 14-alpha sterol demethylase makes it useful against some [ …
Matched Categories: … Triazole and tetrazole derivatives ... Metabolic Side Effects of Drugs and Substances ... Steroid Synthesis Inhibitors ... Antimycotics for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … VFEND (200 MG POWDER FOR SOLUTION FOR INFUSION ... Vortimal Voriconazole 200mg POWDER FOR SOLUTION FOR INFUSION ... VORICONAZOLE ALVOGEN (200 MG POWDER FOR SOLUTION FOR INFUSION) …
Ropivacaine is an aminoamide local anesthetic drug marketed by AstraZeneca under the trade name Naropin. It exists as a racemate of its S- and R-enantiomers, although the marketed form is supplied only as the purified S-enantiomer.
Approved
Matched Description: … It exists as a racemate of its S- and R-enantiomers, although the marketed form is supplied only as the …
Matched Products: … ROPIVACAINE-AFT SOLUTION FOR INJECTION 1% W/V ... ROPIVACAINE-AFT SOLUTION FOR INFUSION 0.2% W/V ... ROPIVACAINE-AFT SOLUTION FOR INJECTION 0.2% W/V …
Approved
Experimental
Investigational
Matched Categories: … Alimentary Tract and Metabolism ... Drugs for Constipation …
Matched Products: … EVAGEL POWDER FOR ORAL SOLUTION 3.5g ... CONSIGEL POWDER FOR ORAL SOLUTION 3.5G …
Insulin detemir is a long-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes.[A2358, A2359, A2360, A44] Insulin is typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human insulin, a peptide hormone produced by beta...
Approved
Matched Description: … [A2358, A2359, A2360, A44] Insulin also inhibits hepatic glucose production, enhances protein synthesis ... 1 and Type 2 Diabetes. ... , and inhibits lipolysis and proteolysis among many other functions. …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Levemir FlexPen 100U/ML Solution for injection in a prefilled pen ... Levemir® FlexPen® 100 U/ml Solution for Injection in Pre-filled Pen …
Busulfan is a bifunctional alkylating agent, having a selective immunosuppressive effect on bone marrow. It is not a structural analog of the nitrogen mustards. It has been used in the palliative treatment of chronic myeloid leukemia (myeloid leukemia, chronic), but although symptomatic relief is provided, no permanent remission is brought...
Approved
Investigational
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … Busulfan Kabi Injection 6mg/ml Concentrate for Solution for Infusion ... Busulfan for Injection …
Antiprotozoal agent effective in trypanosomiasis, leishmaniasis, and some fungal infections; used in treatment of pneumocystis pneumonia in HIV-infected patients. It may cause diabetes mellitus, central nervous system damage, and other toxic effects.
Approved
Investigational
Matched Description: … Antiprotozoal agent effective in trypanosomiasis, leishmaniasis, and some fungal infections; used in ... It may cause diabetes mellitus, central nervous system damage, and other toxic effects. …
Matched Categories: … Agents Against Leishmaniasis and Trypanosomiasis ... Antiparasitic Products, Insecticides and Repellents ... Antibiotics for Pneumocystis Pneumonia …
Matched Products: … Pentamidine Isetionate for Injection BP ... DBL™ PENTAMIDINE ISETHIONATE FOR INJECTION BP 300mg ... DBL PENTAMIDINE ISETHIONATE FOR INJECTION BP 300 mg/vial …
Plerixafor is a small-molecule inhibitor of C-X-C chemokine receptor type 4 (CXCR4) that acts as a hematopoietic stem cell mobilizer.[A7117,L45678] It is used to stimulate the release of stem cells from the bone marrow into the blood in patients with non-Hodgkin's lymphoma (NHL) and multiple myeloma to stimulate their immune...
Approved
Investigational
Matched Iupac: … 1-({4-[(1,4,8,11-tetraazacyclotetradecan-1-yl)methyl]phenyl}methyl)-1,4,8,11-tetraazacyclotetradecane …
Matched Description: … of achieving the optimal CD34+ cell target for tandem transplantation in fewer apheresis procedures. ... Since CXCR4 and SDF-1α are involved in the trafficking and homing of CD34+ cells to the marrow compartment ... [A7115] Plerixafor has orphan drug status in the United States and European Union and was approved …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … Mozobil 20 mg/ml solution for injection ... Mozobil Solution for Injection 20mg/ml …
Experimental
Matched Name: … 2,2,2-TRIFLUORO-1-{5-[(3-PHENYL-5,6-DIHYDROIMIDAZO[1,2-A]PYRAZIN-7(8H)-YL)CARBONYL]THIOPHEN-2-YL}ETHANE …
Matched Iupac: … 2,2,2-trifluoro-1-(5-{3-phenyl-5H,6H,7H,8H-imidazo[1,2-a]pyrazine-7-carbonyl}thiophen-2-yl)ethane-1,1 …
Experimental
Matched Name: … 3-[6-bromo-2-fluoro-3-(1H-pyrazolo[3,4-c]pyridazin-3-ylmethyl)phenoxy]-5-chlorobenzonitrile …
Matched Iupac: … 3-[6-bromo-2-fluoro-3-({1H-pyrazolo[3,4-c]pyridazin-3-yl}methyl)phenoxy]-5-chlorobenzonitrile …
5-(7-(6-chloro-4-(5-hydro-4-methyl-2-oxazolyl)phenoxy)heptyl)-3-methyl isoxazole is a solid. This compound belongs to the phenol ethers. These are aromatic compounds containing an ether group substituted with a benzene ring. 5-(7-(6-chloro-4-(5-hydro-4-methyl-2-oxazolyl)phenoxy)heptyl)-3-methyl isoxazole targets the protein genome polyprotein.
Experimental
Matched Name: … 5-(7-(6-chloro-4-(5-hydro-4-methyl-2-oxazolyl)phenoxy)heptyl)-3-methyl isoxazole …
Matched Iupac: … 5-(7-{2-chloro-4-[(4S)-4-methyl-4,5-dihydro-1,3-oxazol-2-yl]phenoxy}heptyl)-3-methyl-1,2-oxazole …
Matched Description: … This compound belongs to the phenol ethers. ... 5-(7-(6-chloro-4-(5-hydro-4-methyl-2-oxazolyl)phenoxy)heptyl)-3-methyl isoxazole is a solid. ... containing an ether group substituted with a benzene ring. 5-(7-(6-chloro-4-(5-hydro-4-methyl-2-oxazolyl)phenoxy
The 4-carboxyaldehyde form of vitamin B 6 which is converted to pyridoxal phosphate which is a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. [PubChem]
Experimental
Nutraceutical
Matched Synonyms: … 2-methyl-3-hydroxy-4-formyl-5-hydroxymethylpyridine …
Matched Description: … for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic ... The 4-carboxyaldehyde form of vitamin B 6 which is converted to pyridoxal phosphate which is a coenzyme …
Cholestyramine or colestyramine is a bile acid sequestrant. Bile acid sequestrants are polymeric compounds which serve as ion exchange resins. Cholestyramine resin is quite hydrophilic, but insoluble in water.
Approved
Investigational
Matched Categories: … Hypolipidemic Agents Indicated for Hyperlipidemia ... Non-statin Hypolipidemic Agents Indicated for Hyperlipidemia …
Matched Products: … Cholestyramine Powder for Suspension ... Cholestyramine for Oral Suspension ... PHL-cholestyramine Powder for Suspension 400gm/can …
Thiocolchicoside is a semi-synthetic derivative of the colchicine, a natural anti-inflammatory glycoside which originates from the flower seeds of Superba gloriosa. It is a muscle relaxant with anti-inflammatory and analgesic effects. It has potent convulsant activity and should not be administered to individuals prone to seizures.
Experimental
Matched Description: … It is a muscle relaxant with anti-inflammatory and analgesic effects. ... It has potent convulsant activity and should not be administered to individuals prone to seizures. ... Thiocolchicoside is a semi-synthetic derivative of the colchicine, a natural anti-inflammatory glycoside …
Matched Mixtures name: … TIOMED® FORTE ... TIOMED® FORTE
Matched Products: … MYAL FORT 8 MG KAPSUL, 10 ADET ... MYAL FORT 8 MG KAPSUL, 14 ADET ... MYAL FORT 8 MG KAPSUL, 20 ADET …
Investigational
Matched Synonyms: … -cyano-3-phenoxybenzyl (rs)-2-(4-chloro-phenyl)-3-methylbutyrate …
Iodine is commonly used as an antiseptic for minor cuts and abrasions, preventing infections that may result from contaminated wounds. Additionally, iodine has been studied in the treatment of fibrocystic disease and breast cancer.[A3413,A192153,A192156,A192159]
Approved
Investigational
Matched Description: … Iodine is commonly used as an antiseptic for minor cuts and abrasions, preventing infections that may ... Additionally, iodine has been studied in the treatment of fibrocystic disease and breast cancer. …
Matched Mixtures name: … For-2 ... PEDIVITE FORTE CAPSULE ... Doctor's Choice Brand for Men …
Matched Categories: … Antiseptics and Disinfectants ... Diet, Food, and Nutrition ... Herbs and Natural Products …
Matched Products: … XENETIX 350-50ML SOLN FOR INTRAVASCULAR INJ ... XENETIX 300-50ML SOLN FOR INTRAVASCULAR INJ ... XENETIX 350-100ML SOLN FOR INTRAVASCULAR INJ …
Pantoprazole is a first-generation proton pump inhibitor (PPI) used for the management of gastroesophageal reflux disease (GERD), for gastric protection to prevent recurrence of stomach ulcers or gastric damage from chronic use of NSAIDs, and for the treatment of pathological hypersecretory conditions including Zollinger-Ellison (ZE) Syndrome. It can also be...
Approved
Matched Description: … antibiotics including [amoxicillin], [clarithromycin], and [metronidazole], for example. ... from chronic use of NSAIDs, and for the treatment of pathological hypersecretory conditions including ... and bone fractures later in life. …
Matched Categories: … Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord) ... Alimentary Tract and Metabolism ... pantoprazole, amoxicillin and clarithromycin ... pantoprazole, amoxicillin, clarithromycin and metronidazole ... Drugs for Acid Related Disorders …
Matched Products: … panpriva 40mg Powder for Solution for Injection ... Pantoprazole NORMON powder for solution for injection 40mg ... ALPANZOLE POWDER FOR SOLUTION FOR INJECTION 40 MG/VIAL …
Dulaglutide, marketed by Eli Lilly as Trulicity, is a once-weekly subcutaneous glucagon-like peptide-1 (GLP-1) receptor agonist designed using recombinant DNA technology; it has been approved as an adjunct therapy to diet and exercise in the management of 2 diabetes (T2DM). Dulaglutide was initially approved by the FDA in 2014, and...
Approved
Investigational
Matched Description: … [A236070] Dulaglutide was initially approved by the FDA in 2014, and in February 2020 was approved for ... use in patients with T2DM and multiple cardiovascular risk factors for the prevention of cardiovascular ... agonist designed using recombinant DNA technology; it has been approved as an adjunct therapy to diet and
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Trulicity 1.5mg solution for injection in pre-filled pen ... Trulicity 0.75mg solution for injection in pre-filled pen …
Peginterferon alfa-2a is a form of recombinant interferon used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most...
Approved
Investigational
Matched Description: … 36% for genotype 1 and 59% for genotypes 2-6 after 48 weeks of treatment. ... development of endocrine and autoimmune disorders, retinopathies, cardiovascular and neuropsychiatric ... categorized into nine distinct genotypes, with genotype 1 being the most common in the United States, and
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Treatments for Hepatitis C ... Intercellular Signaling Peptides and Proteins …
Matched Products: … PEGASYS PRE-FILLED SYRINGE FOR INJECTION 180 mcg/0.5 ml ... PEGASYS PRE-FILLED SYRINGE FOR INJECTION 135 mcg/0.5 ml …
Micafungin is an antifungal drug. It belongs to the antifungal class of compounds known as echinocandins and exerts its effect by inhibiting the synthesis of 1,3-beta-D-glucan, an integral component of the fungal cell wall.
Approved
Investigational
Matched Iupac: … 11,20,21,25-tetrahydroxy-15-[(1R)-1-hydroxyethyl]-26-methyl-2,5,8,14,17,23-hexaoxo-18-(4-{5-[4-(pentyloxy)phenyl
Matched Description: … It belongs to the antifungal class of compounds known as echinocandins and exerts its effect by inhibiting ... the synthesis of 1,3-beta-D-glucan, an integral component of the fungal cell wall. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antimycotics for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … Mycamine 50 mg/vial powder for solution for infusion ... MYCAMINE POWDER FOR SOLUTION FOR INFUSION 50MG/VIAL ... Micafungin for Injection …
Lurbinectedin is a DNA alkylating agent that has been investigated in the treatment of a variety of cancers, including mesothelioma, chronic lymphocytic leukemia (CLL), breast cancer, and small-cell lung cancer (SCLC). It is a derivative of the marine-derived agent ecteinascidin (trabectedin), an anticancer agent found in extracts of the tunicate...
Approved
Investigational
Matched Description: … including mesothelioma,[A214325] chronic lymphocytic leukemia (CLL),[A214328] breast cancer,[A214322] and ... [L14336] This accelerated approval is based on the rate and duration of therapeutic response observed ... [A214331] On June 15, 2020, the FDA granted accelerated approval and orphan drug designation to lurbinectedin …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … ZEPZELCA POWDER FOR SOLUTION FOR INFUSION 4MG/VIAL …
Levofloxacin is a fluoroquinolone antibiotic and the optical S-(-) isomer of racemic ofloxacin. It reportedly carries 8 to 128-fold more activity against both gram-negative and gram-positive bacteria compared to R-(+)-ofloxacin and remains stereochemically stable following administration (i.e. it does not invert to the inactive isomer). Levofloxacin, along with other quinolones...
Approved
Investigational
Matched Synonyms: … Ofloxacin S-(-)-form
Matched Description: … Levofloxacin is a fluoroquinolone antibiotic and the optical S-(-) isomer of racemic [ofloxacin]. ... [A31453,A190756] Levofloxacin was first approved by the FDA in 1996, and was approved in Canada and ... [A190663] It reportedly carries 8 to 128-fold more activity against both gram-negative and gram-positive …
Matched Categories: … Alimentary Tract and Metabolism ... levofloxacin and ornidazole ... Metabolic Side Effects of Drugs and Substances ... lansoprazole, amoxicillin and levofloxacin ... Antibacterials for Systemic Use …
Matched Products: … For Infusion 5mg/ml ... Levores 5mg/ml Solution for Infusion ... JW Levofloxacin Solution for Infusion 5mg/mL …
Displaying drugs 1576 - 1600 of 1946 in total