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Displaying drugs 1601 - 1625 of 2021 in total

Palbociclib

Palbociclib is a piperazine pyridopyrimidine that acts in the cell cycle machinery. It is a second generation cyclin-dependent kinase inhibitor selected from a group of pyridopyrimidine compounds due to its favorable physical and pharmaceutical properties. Palbociclib was developed by Pfizer Inc after the discovery that identified the cyclin-dependent kinases as...
Approved
Investigational
Matched Description: … inhibitor[A176798] selected from a group of pyridopyrimidine compounds due to its favorable physical and ... electronic health records demonstrating safety and clinical efficacy. ... on March 2015 for the treatment of HR-positive, HER2-negative advanced or metastatic breast cancer and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … IBRELYN 100 (Palbociclib Capsules 100mg) ... PALVORED 100 (PALBOCICLIB CAPSULES 100MG) ... Ibrance Capsules 100mg …

Phenothrin

Experimental
Matched Categories: … Antiparasitic Products, Insecticides and Repellents ... Scabicides, Insecticides and Repellents …
Matched Products: … ANTI-BIT 408 MG/100 ML ŞAMPUAN, 100 ML ... ANTI-BIT 408 MG/100 ML ŞAMPUAN, 150 ML …

Chlorpromazine

The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class, chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking dopamine receptors. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
Approved
Investigational
Vet approved
Matched Description: … Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the …
Matched Products: … CHLORPROMAZINE 100 TABLET 100 mg ... โปเกตอล 100 ... CEPEZET 100 …

Topiramate

Topiramate is a anti-epileptic drug used to manage seizures and prevent migraines. It was initially approved by the FDA in 1996. In 2004, topiramate was approved for the prevention of migraine in adults.[A188309,L10544,L43478] Since 2012, the extended-release formulation has been approved in combination with phentermine for chronic weight management therapy...
Approved
Matched Description: … Topiramate is a anti-epileptic drug used to manage seizures and prevent migraines. ... topiramate from other antiepileptic drugs are a monosaccharide chemical structure containing a sulfamate, and …
Matched Salts name: … Topiramate calcium ... Topiramate potassium …
Matched Categories: … Alimentary Tract and Metabolism ... phentermine and topiramate …
Matched Products: … Qudexy XR ... Trokendi XR ... EXPLIGA XR …

Ferric derisomaltose

Iron deficiency is an extremely common condition and is the most frequent cause of anemia worldwide. Iron deficiency results when iron intake, iron stores, and loss of iron from the body do not adequately support production of erythrocytes, also known as red blood cells. Though it is generally considered non...
Approved
Matched Iupac: … iron(3+) (2S,3R,4R,5R)-6-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-({[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6 …
Matched Description: … Iron deficiency results when iron intake, iron stores, and loss of iron from the body do not adequately ... Iron deficiency is an extremely common condition and is the most frequent cause of anemia worldwide. ... This drug is a complex of iron (III) hydroxide and derisomaltose. …
Matched Categories: … Iron Compounds ... Iron Preparations ... Anemia, Iron-Deficiency ... Parenteral Iron Replacement …
Matched Products: … Monofer 100 mg/ml Injektions- oder Infusionslösung ... MONOFER® SOLUTION FOR INJECTION OR INFUSION 100 MG/ML ... Monofer 100 mg/ml solution for injection/infusion in vials …

Rabies immune globulin, human

IMOGAM Rabies Pasteurized is indicated for post-exposure prophylaxis in persons suspected of exposure to rabies, who have not previously received a complete immunization regimen with a cell culture produced rabies vaccine. Persons previously vaccinated with other types of rabies vaccines in whom adequate antibody levels have not been demonstrated should...
Approved
Matched Description: … adequate antibody levels have not been demonstrated should receive full post-exposure prophylaxis with RIG and ... Recommendations for passive and/or active immunization after exposure to an animal suspected of having ... Advisory Committee on Immunization (NACI), the Advisory Committee on Immunization Practices (ACIP), and …
Matched Products: … EQUIRAB 1000 IU/5ML IM/SC ÇÖZELTI IÇEREN FLAKON, 1 ADET …

Cefdinir

Cefdinir, also known as Omnicef, is a semi-synthetic, broad-spectrum antibiotic belonging to the third generation of the cephalosporin class. It has been proven to be effective for the treatment of common bacterial infections in the ear, sinus, throat, lungs, and skin. Cefdinir was approved by the FDA in 1997 to...
Approved
Matched International brands: … Xi Fu Ni …
Matched Description: … to be effective for the treatment of common bacterial infections in the ear, sinus, throat, lungs, and ... Cefdinir was approved by the FDA in 1997 to treat a variety of mild to moderate infections and was initially …
Matched Mixtures name: … TAMCEF PLUS 125 MG + 62,5 MG / 5 ML ORAL SUSPANSIYON HAZIRLAMAK ICIN KURU TOZ, 100 ML …
Matched Products: … แซมเนียร์ 100 มก. ชนิดแคปซูล ... CLASEM 125 MG/5ML ORAL SUSPANSIYON ICIN TOZ, 100 ML ... CLASEM 250 MG/5ML ORAL SUSPANSIYON ICIN TOZ, 100 ML …

Ezogabine

Ezogabine (D23129) is a close structural analog of the centrally acting analgesic flupitrine. It is a neuronal potassium channel opener being developed as a first-in-class antiepileptic drug (AED) and is currently being studied in Phase 3 trials as an adjunctive treatment for partial-onset seizures in adult patients with refractory epilepsy....
Approved
Investigational
Matched Synonyms: … ethyl {2-amino-4-[(4-fluorobenzyl)amino]phenyl}carbamate …
Matched Iupac: … ethyl N-(2-amino-4-{[(4-fluorophenyl)methyl]amino}phenyl)carbamate …
Matched Description: … ) and is currently being studied in Phase 3 trials as an adjunctive treatment for partial-onset seizures ... It is a neuronal potassium channel opener being developed as a first-in-class antiepileptic drug (AED …
Matched Categories: … Potassium Channel Opener …

Dasatinib

Dasatinib is an orally available multikinase inhibitor indicated for the treatment of Philadelphia chromosome (Ph)-positive leukemias.[A2224,L45171] Ph is a chromosomal abnormality found in patients with chronic myelogenous leukemia (CML) and acute lymphocytic leukemia (ALL), where the ABL tyrosine kinase and the breakpoint cluster region (BCR) gene transcribe the chimeric protein...
Approved
Investigational
Matched Description: … pathogenesis of CML and 15-30% of ALL cases. ... A2224,L45171] Ph is a chromosomal abnormality found in patients with chronic myelogenous leukemia (CML) and ... acute lymphocytic leukemia (ALL), where the ABL tyrosine kinase and the breakpoint cluster region (BCR …
Matched Salts name: … Dasatinib monolauryl sulfate …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … LITEDA 100 MG ... REMBRE 100 MG ... Pharma 100 mg-Filmtabletten …

Trazodone

Trazodone is triazolopyridine derivative from the serotonin receptor antagonists and reuptake inhibitors (SARIs) class of antidepressants. It is used in adults and has been shown to be comparable in efficacy to other drugs such as tricyclic antidepressants (TCAs), selective serotonin reuptake inhibitors (SSRIs), and serotonin-norepinephrine receptor inhibitor (SNRIs) in the...
Approved
Investigational
Matched Description: … Trazodone is triazolopyridine derivative from the serotonin receptor antagonists and reuptake inhibitors ... [A181180] It is used in adults and has been shown to be comparable in efficacy to other drugs such as ... tricyclic antidepressants (TCAs), selective serotonin reuptake inhibitors (SSRIs), and serotonin-norepinephrine …
Matched Categories: … Serotonin antagonist and reuptake inhibitors (SARIs) …
Matched Products: … DESYREL XL 150 MG UZATILMIŞ SALIMLI FİLM TABLET , 10 TABLET ... DESYREL XL 150 MG UZATILMIŞ SALIMLI FİLM TABLET , 14 TABLET ... DESYREL XL 150 MG UZATILMIŞ SALIMLI FİLM TABLET , 20 TABLET …

Palivizumab

Humanized monoclonal antibody (IgG1k) produced by recombinant DNA technology, directed to an epitope in the A antigenic site of the F protein of respiratory syncytial virus (RSV). Synagis is a composite of human (95%) and murine (5%) antibody sequences. The human heavy chain sequence was derived from the constant domains...
Approved
Investigational
Matched Description: … regions of the VH genes Cor (1) and Cess (2). ... Synagis is a composite of human (95%) and murine (5%) antibody sequences. ... The human heavy chain sequence was derived from the constant domains of human IgG1 and the variable framework …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Immune Sera and Immunoglobulins …
Matched Products: … Synagis 100mg/ml solution for Injection ... SYNAGIS SOLUTION FOR INJECTION 100MG/ML ... SYNAGIS®100 MG SOLUCION PARA INYECCIÓN …

Spironolactone

Spironolactone is a potassium-sparing diuretic. It binds to mineralocorticoid receptors and functions as aldosterone antagonists. It promotes sodium and water excretion and potassium retention. Spironolactone was originally developed purely for this ability before other pharmacodynamic properties of the drug were discovered.[A11837, A178246] It is indicated to treat several conditions, including...
Approved
Matched Description: … [A178192] It promotes sodium and water excretion and potassium retention. ... Spironolactone is a potassium-sparing diuretic. ... It binds to mineralocorticoid receptors and functions as aldosterone antagonists. …
Matched Mixtures name: … Spironolactone and Hydrochlorothiazide ... Spironolactone and Hydrochlorothiazide ... Spironolactone and Hydrochlorothiazide …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists ... Potassium-Sparing Diuretics …
Matched Products: … SPIROLON 100 TABLET 100 mg ... CARPIATON 100 ... LETONAL 100 …

Itraconazole

First synthesized in the early 1980s, itraconazole is a broad-spectrum triazole antifungal agent used to treat a variety of infections. It is a 1:1:1:1 racemic mixture of four diastereomers, made up of two enantiomeric pairs, each possessing three chiral centers. Itraconazole was first approved in the US in 1992 and...
Approved
Investigational
Matched Description: … [L50051] Itraconazole was first approved in the US in 1992 [L50056] and is available orally. …
Matched Categories: … Triazole and tetrazole derivatives ... Metabolic Side Effects of Drugs and Substances …
Matched Products: … CANDIFORCE-100 Itraconazole Capsules BP 100 mg ... Inox Capsule 100 mg ... MICOTRAZOL® 100 MG …

Ritonavir

Ritonavir is an HIV protease inhibitor that interferes with the reproductive cycle of HIV. Although it was initially developed as an independent antiviral agent, it has been shown to possess advantageous properties in combination regimens with low-dose ritonavir and other protease inhibitors. It is now more commonly used as a...
Approved
Investigational
Matched Iupac: … methyl({[2-(propan-2-yl)-1,3-thiazol-4-yl]methyl})carbamoyl]amino}butanamido]-1,6-diphenylhexan-2-yl]carbamate …
Matched Description: … formulations and as capsules. ... it has been shown to possess advantageous properties in combination regimens with low-dose ritonavir and ... protease inhibitors such as [DB09297] and overall drug exposure. …
Matched Mixtures name: … Viekira XR ... Lopinavir and Ritonavir ... Lopinavir and ritonavir …
Matched Categories: … lopinavir and ritonavir ... darunavir and ritonavir ... atazanavir and ritonavir ... nirmatrelvir and ritonavir ... ombitasvir, paritaprevir and ritonavir …
Matched Products: … Norvir Tablet 100mg ... Norvir Tablets 100 mg ... RINAVO® 100 MG TABLETAS …

Alanyl glutamine

Alanyl Glutamine is under investigation in clinical trial NCT00338221 (Clinical Trial of Alanyl-Glutamine or Glycine in Children With Persistent Diarrhea or Malnutrition).
Investigational
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions …
Matched Products: … DIPEPTIVEN 100 ML SOLUSYON ... DIPEPTIVEN INFUSION (50ML, 100ML GLASS BOTTLE) ... DİPEPİTVEN %20 İNFÜZYONLUK ÇÖZELTİ KONSANTRESİ, 100 ML …

2-Methyl-2-propanyl [(1R)-2-methyl-1-(1,3,4-oxadiazol-2-yl)propyl]carbamate

Experimental
Matched Name: … 2-Methyl-2-propanyl [(1R)-2-methyl-1-(1,3,4-oxadiazol-2-yl)propyl]carbamate …
Matched Iupac: … tert-butyl N-[(1R)-2-methyl-1-(1,3,4-oxadiazol-2-yl)propyl]carbamate …

Acarbose

Acarbose is a complex oligosaccharide that acts as an inhibitor of several enzymes responsible for the breakdown of complex carbohydrates in the intestines. It inhibits both pancreatic alpha-amylase and membrane-bound alpha-glucosidases - including intestinal glucoamylase, sucrase, maltase, and isomaltase - which are responsible for the metabolism of complex starches and...
Approved
Investigational
Matched Description: … starches and oligo-, tri-, and disaccharides into absorbable simple sugars. ... It inhibits both pancreatic alpha-amylase and membrane-bound alpha-glucosidases - including intestinal ... the subsequent postprandial increase in blood glucose and insulin levels. …
Matched Categories: … Alimentary Tract and Metabolism ... metformin and acarbose …
Matched Products: … GLUCOBAY 100 TABLET 100 mg ... DITRIUM 100 ... GLUCOBAY 100 …

Acebutolol

A cardioselective beta-adrenergic antagonist with little effect on the bronchial receptors. The drug has stabilizing and quinidine-like effects on cardiac rhythm as well as weak inherent sympathomimetic action.
Approved
Investigational
Matched Description: … The drug has stabilizing and quinidine-like effects on cardiac rhythm as well as weak inherent sympathomimetic …
Matched Categories: … Beta Blocking Agents and Thiazides ... Beta Blocking Agents, Selective, and Thiazides ... acebutolol and thiazides ... Alcohols ... Amino Alcohols …
Matched Products: … Rhotral 100 ... Monitan 100 ... Acebutolol-100 …

Minocycline

Minocycline was first described in the literacture in 1966. It is a second generation tetracycline antibiotic that is active against gram-negative and gram-positive bacteria. Like other semisynthetic tetracyclines, minocycline has modifications to carbons 7-9 on the D ring to generate higher efficacy than previous tetracyclines. Minocycline was granted FDA approval...
Approved
Investigational
Matched Description: … [A190681] It is a second generation tetracycline antibiotic that is active against gram-negative and …
Matched Categories: … Alimentary Tract and Metabolism ... Antiinfectives and Antiseptics for Local Oral Treatment ... Medications that reduce magnesium levels …
Matched Products: … SKID 100 ... Enca 100mg ... MYNOFECT - 100 …

Abemaciclib

Abemaciclib is an antitumor agent and dual inhibitor of cyclin-dependent kinases 4 (CDK4) and 6 (CDK6) that are involved in the cell cycle and promotion of cancer cell growth in case of unregulated activity. On September 28, 2017, FDA granted approval of abemaciclib treatment under the market name Verzenio for...
Approved
Investigational
Matched Description: … Abemaciclib is an antitumor agent and dual inhibitor of cyclin-dependent kinases 4 (CDK4) and 6 (CDK6 ... ) that are involved in the cell cycle and promotion of cancer cell growth in case of unregulated activity ... granted approval of abemaciclib treatment under the market name Verzenio for the treatment of HR-positive and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … VERZENIO® 100 MG ... เวอซีนิโอ (100 มก.) ... VERZENIO FILM-COATED TABLET 100MG …

Bendamustine

Bendamustine is a nitrogen mustard drug which has been used in the treatment of chronic lymphocytic leukemia (CLL) and indolent B-cell non-Hodgkin lymphoma (NHL). Bendamustine is a bifunctional mechlorethamine derivative capable of forming electrophilic alkyl groups that covalently bond to other molecules. Through this function as an alkylating agent, bendamustine...
Approved
Investigational
Matched Description: … a nitrogen mustard drug which has been used in the treatment of chronic lymphocytic leukemia (CLL) and ... Through this function as an alkylating agent, bendamustine causes intra- and inter-strand crosslinks ... It is active against both active and quiescent cells, although the exact mechanism of action is unknown …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … BENTERO 100 ... RAMIZA 100 ... XEBINA®100MG …

(3S)-3-cyclopentyl-6-methyl-7-[(4-methylpiperazin-1-yl)sulfonyl]-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide

Experimental
Matched Name: … cyclopentyl-6-methyl-7-[(4-methylpiperazin-1-yl)sulfonyl]-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide …

Mepolizumab

Eosinophils are involved in inflammatory immune responses, and prolonged hypereosinophilia (typically defined as absolute eosinophil levels of 1500/mm3 or more) is associated with a spectrum of diseases, including severe asthma, eosinophilic granulomatosis with polyangiitis (EGPA), and hypereosinophilic syndrome (HES). The pathogenesis of eosinophilia is complex, but IL-5 is recognized as...
Approved
Investigational
Matched Description: … Eosinophils are involved in inflammatory immune responses, and prolonged hypereosinophilia (typically ... Activated eosinophils further stimulate an inflammatory response and also induce tissue lesions and promote ... spectrum of diseases, including severe asthma, eosinophilic granulomatosis with polyangiitis (EGPA), and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … นูคาล่า (100 มก.) ... NUCALA® 100MG/ML SOLUCION INYECTABLE ... NUCALA POWDER FOR SOLUTION FOR INJECTION 100mg …

Histidine

An essential amino acid that is required for the production of histamine.
Investigational
Nutraceutical
Matched Mixtures name: … Aminosyn II and Dextrose ... Aminosyn II and Dextrose ... Aminosyn Sulfite Free …
Matched Salts name: … Copper histidine …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … CAREDO Treating Periodontitis Toothpastes 100g …

Pentosan polysulfate

Pentosan polysulfate is a sulfated pentosyl polysaccharide with heparin-like properties.
Approved
Matched Salts name: … Calcium pentosan polysulfate …
Matched Categories: … Genito Urinary System and Sex Hormones …
Matched Products: … ELMIRON 100 MG KAPSÜL, 100 ADET ... Elmidam 100 mg Sert Kapsül, 100 ADET ... ELMİDAM 100 MG SERT KAPSÜL, 100 ADET …
Displaying drugs 1601 - 1625 of 2021 in total