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Displaying drugs 1676 - 1700 of 1990 in total

Nanrilkefusp alfa

Nanrilkefusp alfa is a human fusion protein consisting of the cytokine interleukin (IL)-15 and the high-affinity binding sushi+ domain of IL-15 receptor alpha (IL-15Ra).
Investigational
Matched Description: … Nanrilkefusp alfa is a human fusion protein consisting of the cytokine interleukin (IL)-15 and the high-affinity …

Staurosporine

An indolocarbazole that is a potent protein kinase C inhibitor which enhances cAMP-mediated responses in human neuroblastoma cells. (Biochem Biophys Res Commun 1995;214(3):1114-20)
Experimental
Matched Description: … indolocarbazole that is a potent protein kinase C inhibitor which enhances cAMP-mediated responses in human …

Tasquinimod

The quinoline-3-carboxamide anti-angiogenic agent, tasquinimod, enhances the anti-prostate cancer efficacy of androgen ablation and taxotere without effecting serum PSA directly in human xenografts
Investigational
Matched Description: … taxotere without effecting serum PSA directly in human xenografts ... anti-angiogenic agent, tasquinimod, enhances the anti-prostate cancer efficacy of androgen ablation and …

EP-2104R

EP-2104R is an imaging pharmaceutical under development for the detection of blood clots. It is the first targeted high-resolution technique designed to visualize blood clots directly. It is being developed by EPIX Pharmaceuticals, Inc.
Investigational
Matched Categories: … Amino Acids, Peptides, and Proteins …

Namilumab

Namilumab has been used in trials studying the treatment of Plaque Psoriasis and Rheumatoid Arthritis.
Investigational
Matched Description: … Namilumab has been used in trials studying the treatment of Plaque Psoriasis and Rheumatoid Arthritis …
Matched Categories: … Amino Acids, Peptides, and Proteins …

ATP

An adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
Investigational
Nutraceutical
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …

IRX-2

IRX-2 contains a human leukocyte-derived cytokine mixture. It is being investigated to promote or enhance an anti-cancer immune response.
Investigational
Matched Description: … IRX-2 contains a human leukocyte-derived cytokine mixture. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …

Melarsoprol

Melarsoprol is under investigation in clinical trial NCT00330148 (Randomized Clinical Trial of Three Drug Combinations for Late-Stage Gambiense Human African Trypanosomiasis).
Investigational
Matched Description: … clinical trial NCT00330148 (Randomized Clinical Trial of Three Drug Combinations for Late-Stage Gambiense Human …
Matched Categories: … Agents Against Leishmaniasis and Trypanosomiasis ... Antiparasitic Products, Insecticides and Repellents …

TG-1042

TG-1042 (formerly known as ASN-002) is a recombinant adenovirus carrying the cDNA coding sequence for the human interferon gamma gene.
Investigational
Matched Description: … 1042 (formerly known as ASN-002) is a recombinant adenovirus carrying the cDNA coding sequence for the human …

TNX-901

TNX-901 is a therapeutic monoclonal antibodies designed to address significant unmet medical needs in the areas of asthma, allergy, inflammation and other diseases affecting the human immune system.
Investigational
Matched Description: … other diseases affecting the human immune system. ... antibodies designed to address significant unmet medical needs in the areas of asthma, allergy, inflammation and …
Matched Categories: … Amino Acids, Peptides, and Proteins …

RC118

RC118 is an antibody-drug conjugate that consists of a recombinant humanized IgG1 anti-Claudin18.2 monoclonal antibody conjugated to MMAE.
Investigational

Custirsen

Custirsen is a benzopyran with potential antineoplastic activity. Custirsen acts as a selective estrogen receptor modulator (SERM), inhibiting the proliferation of estrogen-sensitive breast cancer cells. This agent also inhibits growth and induces apoptosis of glioblastoma cells via a mechanism independent of estrogen receptor-related mechanisms. Custirsen is also being investigated in...
Investigational
Matched Description: … This agent also inhibits growth and induces apoptosis of glioblastoma cells via a mechanism independent …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …

PBGM01

PBGM01 is a non-replicating recombinant adeno-associated virus serotype hu68 vector, which contains human GLB1 transgene encoding the galactosidase beta 1 enzyme.
Investigational
Matched Description: … PBGM01 is a non-replicating recombinant adeno-associated virus serotype hu68 vector, which contains human …

AK119

AK119 is a humanized anti-CD73 monoclonal antibody being investigated in the clinical trial NCT04516564 (A Study of AK119 (Anti-CD73 Antibody), a Treatment for COVID-19, in Healthy Subjects).
Investigational

Maxy-G34

MAXY-G34 is a pegylated variant of human granulocyte-colony stimulating factor (G-CSF). This variant contains multiple non-naturally occurring lysines that have been introduced into alpha helixes of wild type human G-CSF as PEGylation sites, and from which multiple undesired, naturally occurring lysines have been removed as compared to wild type human...
Investigational
Matched Description: … MAXY-G34 is a pegylated variant of human granulocyte-colony stimulating factor (G-CSF). ... 16, 34, 40, 105 and 159. ... removed as compared to wild type human G-CSF to avoid PEGylation of such sites. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …

Peptide YY (3-36)

Peptide YY (3-36), a synthetic human PYY 3-36, is a compound being evaluated for the treatment of obesity. It reduces appetite and increases satiety in obese patients.
Investigational
Matched Description: … It reduces appetite and increases satiety in obese patients. ... Peptide YY (3-36), a synthetic human PYY 3-36, is a compound being evaluated for the treatment of obesity …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …

Epafipase

Epafipase is under investigation in clinical trial NCT00037687 (Safety and Efficacy of Recombinant Human Platelet-activating Factor Acetylhydrolase for the Treatment of Severe Sepsis).
Investigational
Matched Description: … Epafipase is under investigation in clinical trial NCT00037687 (Safety and Efficacy of Recombinant Human …

ACTX-401

ACTX-401 is a single-stranded, non-replicating recombinant adeno-associated viral vector serotype 9 containing the human immunoglobulin u-binding protein 2 cDNA.
Investigational
Matched Description: … single-stranded, non-replicating recombinant adeno-associated viral vector serotype 9 containing the human …

BB-1701

BB-1701 is a humanized IgG1 kappa monoclonal antibody (anti-HER2 antibody) conjugated to eribulin developed by Bliss Biopharmaceutical.
Investigational

Islatravir

Islatravir is under investigation in clinical trial NCT04233216 (Doravirine/islatravir (DOR/ISL) in Heavily Treatment-experienced (HTE) Participants for Human Immunodeficiency Virus Type 1 (HIV-1) Infection (MK-8591A-019)).
Investigational
Matched Description: … NCT04233216 (Doravirine/islatravir (DOR/ISL) in Heavily Treatment-experienced (HTE) Participants for Human …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …

KITE-585

KITE-585 is an autologous, fully-human anti-B cell maturation antigen (BCMA) chimeric antigen receptor (CAR) T cell therapy. It is being investigated in the treatment of multiple myeloma.
Investigational
Matched Description: … KITE-585 is an autologous, fully-human anti-B cell maturation antigen (BCMA) chimeric antigen receptor …

HMI-203

HMI-203 is an investigational gene therapy developed by Homology Medicines, Inc. It consists of a recombinant adeno-associated virus (AAV) serotype HSC15 (rAAVHSC15) encoding human iduronate-2-sulfatase (hIDS).
Investigational
Matched Description: … It consists of a recombinant adeno-associated virus (AAV) serotype HSC15 (rAAVHSC15) encoding human iduronate …

Elafin

Elafin is a human protein that is produced naturally in the skin, lung and breast, protecting the respective tissue from destruction by the immune system. Elafin’s ability to block the activity of destructive enzymes that are involved in inflammatory reactions makes it a highly promising active compound for the treatment...
Investigational
Matched Description: … Elafin is a human protein that is produced naturally in the skin, lung and breast, protecting the respective ... The excellent tolerability of Elafin in human subjects was demonstrated in a Phase I clinical single ... inflammatory lung diseases or severe reperfusion injuries occurring after heart attacks, serious injuries and …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Ciglitazone

Developed by Takeda Pharmaceuticals in the early 1980s, it is considered the prototypical compound for the thiazolidinedione class. Ciglitazone was never used as a medication, but it sparked interest in the effects of thiazolidinediones. Several analogues were later developed, some of which—such as pioglitazone and troglitazone—made it to the market....
Experimental
Matched Description: … endothelial cell (HUVEC), and osteoblastogenesis in human mesenchymal stem cells. ... Ciglitazone significantly decreases VEGF production by human granulosa cells in an in vitro study, and ... Ciglitazone increases adipogenesis, decreases differentiation and angiogenesis in human umbilical vein …

TAS-106

TAS-106 is a new nucleoside antimetabolite. TAS-106 has demonstrated strong antitumor activity without serious toxicity in nude rat models bearing human tumours .
Investigational
Matched Description: … -106 has demonstrated strong antitumor activity without serious toxicity in nude rat models bearing human …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Displaying drugs 1676 - 1700 of 1990 in total