Displaying drugs 1701 - 1725 of 3090 in total
Chlorambucil
A nitrogen mustard alkylating agent used as antineoplastic agent for the treatment of various malignant and nonmalignant diseases. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
Approved
Matched Synonyms: … Phenylbutyric acid nitrogen mustard ... 4-(p-bis(beta-chloroethyl)aminophenyl)butyric acid ... 4-(p-bis(β-chloroethyl)aminophenyl)butyric acid …
Matched Iupac: … 4-{4-[bis(2-chloroethyl)amino]phenyl}butanoic acid …
Matched Description: … nitrogen mustard alkylating agent used as antineoplastic agent for the treatment of various malignant and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Iupac: … 4-{4-[bis(2-chloroethyl)amino]phenyl}butanoic acid …
Matched Description: … nitrogen mustard alkylating agent used as antineoplastic agent for the treatment of various malignant and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
m-Hydroxyhippuric acid
Experimental
Matched Synonyms: … 3-hydroxyhippuric acid ... 2-[(3-hydroxyphenyl)formamido]acetic acid …
Matched Name: … m-Hydroxyhippuric acid …
Matched Iupac: … 2-[(3-hydroxyphenyl)formamido]acetic acid …
Matched Categories: … Benzamides and benzamide derivatives ... Keto Acids ... Acids, Carbocyclic ... Carboxylic Acids …
Matched Name: … m-Hydroxyhippuric acid …
Matched Iupac: … 2-[(3-hydroxyphenyl)formamido]acetic acid …
Matched Categories: … Benzamides and benzamide derivatives ... Keto Acids ... Acids, Carbocyclic ... Carboxylic Acids …
Testosterone enantate benzilic acid hydrazone
Approved
Experimental
Matched Synonyms: … Testosterone enanthate benzilic acid hydrazone ... Testosterone 17-enanthate 3-benzilic acid hydrazone …
Matched Name: … Testosterone enantate benzilic acid hydrazone …
Matched Categories: … Testosterone and derivatives ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Name: … Testosterone enantate benzilic acid hydrazone …
Matched Categories: … Testosterone and derivatives ... Hormones, Hormone Substitutes, and Hormone Antagonists …
NDI-5001
Investigational
Matched Synonyms: … 1,1'-(1,12-dodecanediyl)bis(cyclopropanecarboxylic acid) ... Cyclopropanecarboxylic acid, 1,1'-(1,12-dodecanediyl)bis- ... 1-(12-(1 carboxycyclopropyl)dodecyl)cyclopropane-1-carboxylic acid …
Ceritinib
Ceritinib is used for the treatment of adults with anaplastic lymphoma kinase (ALK)-positive metastatic non-small cell lung cancer (NSCLC) following failure (secondary to resistance or intolerance) of prior crizotinib therapy. About 4% of patients with NSCLC have a chromosomal rearrangement that generates a fusion gene between EML4 (echinoderm microtubule-associated protein-like...
Approved
Matched Synonyms: … -{2-[(5-chloro-2-{[2-isopropoxy-5-methyl-4-(piperidin-4-yl)phenyl]amino}pyrimidin-4-yl)amino]phenyl}propane …
Matched Iupac: … 5-chloro-N2-[5-methyl-4-(piperidin-4-yl)-2-(propan-2-yloxy)phenyl]-N4-[2-(propane-2-sulfonyl)phenyl]pyrimidine …
Matched Description: … rearrangement that generates a fusion gene between EML4 (echinoderm microtubule-associated protein-like 4) and ... lymphoma kinase), which results in constitutive kinase activity that contributes to carcinogenesis and ... autophosphorylation of ALK, ALK-mediated phosphorylation of the downstream signaling protein STAT3, and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Iupac: … 5-chloro-N2-[5-methyl-4-(piperidin-4-yl)-2-(propan-2-yloxy)phenyl]-N4-[2-(propane-2-sulfonyl)phenyl]pyrimidine …
Matched Description: … rearrangement that generates a fusion gene between EML4 (echinoderm microtubule-associated protein-like 4) and ... lymphoma kinase), which results in constitutive kinase activity that contributes to carcinogenesis and ... autophosphorylation of ALK, ALK-mediated phosphorylation of the downstream signaling protein STAT3, and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Nemvaleukin alfa
Investigational
Matched Synonyms: … 75-133-interleukin 2 (125-serine) (human) fusion protein with peptide linker (gg) fusion protein with ... 75-133-Interleukin 2 [125-serine] (human) fusion protein with peptide linker (GG) fusion protein with …
Baclofen
Baclofen is a gamma-aminobutyric acid (GABA) agonist used as a skeletal muscle relaxant. Although originally designed in 1962 to treat epilepsy, baclofen was not effective in treating this condition but instead was shown to reduce spasticity in selected patients. Baclofen was reintroduced in 1971 as a treatment for spasticity and...
Approved
Matched Synonyms: … 4-Amino-3-(4-chlorophenyl)butyric acid ... DL-4-Amino-3-p-chlorophenylbutanoic acid ... beta-(Aminomethyl)-p-chlorohydrocinnamic acid …
Matched Iupac: … 4-amino-3-(4-chlorophenyl)butanoic acid …
Matched Description: … [A245338] Baclofen was reintroduced in 1971 as a treatment for spasticity and was later approved by the ... used to manage severe muscle spasms of cerebral or spinal cord origins, including multiple sclerosis and ... [L39429] Baclofen was investigated for use in alcohol dependence and withdrawal; however, evidence …
Matched Salts name: … Baclofen hydrochloride …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... gamma-Aminobutyric Acid-ergic Agonist …
Matched Iupac: … 4-amino-3-(4-chlorophenyl)butanoic acid …
Matched Description: … [A245338] Baclofen was reintroduced in 1971 as a treatment for spasticity and was later approved by the ... used to manage severe muscle spasms of cerebral or spinal cord origins, including multiple sclerosis and ... [L39429] Baclofen was investigated for use in alcohol dependence and withdrawal; however, evidence …
Matched Salts name: … Baclofen hydrochloride …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... gamma-Aminobutyric Acid-ergic Agonist …
methyl 4-bromo-N-[8-(hydroxyamino)-8-oxooctanoyl]-L-phenylalaninate
Experimental
Matched Name: … methyl 4-bromo-N-[8-(hydroxyamino)-8-oxooctanoyl]-L-phenylalaninate …
(2,6-Dimethylphenoxy)acetic acid
Experimental
Matched Synonyms: … (2,6-Xylyloxy) acetic acid …
Matched Name: … (2,6-Dimethylphenoxy)acetic acid …
Matched Iupac: … 2-(2,6-dimethylphenoxy)acetic acid …
Matched Name: … (2,6-Dimethylphenoxy)acetic acid …
Matched Iupac: … 2-(2,6-dimethylphenoxy)acetic acid …
Thioctamide
Experimental
Matched Synonyms: … Thioctic acid amide …
Matched Categories: … Enzymes and Coenzymes ... Fatty Acids ... Carboxylic Acids …
Matched Categories: … Enzymes and Coenzymes ... Fatty Acids ... Carboxylic Acids …
METHYL(2-ACETOXY-2-(2-CARBOXY-4-AMINO-PHENYL))ACETATE
Experimental
Matched Name: … METHYL(2-ACETOXY-2-(2-CARBOXY-4-AMINO-PHENYL))ACETATE …
Matched Iupac: … 2-[(1R)-1-(acetyloxy)-2-methoxy-2-oxoethyl]-5-aminobenzoic acid …
Matched Iupac: … 2-[(1R)-1-(acetyloxy)-2-methoxy-2-oxoethyl]-5-aminobenzoic acid …
Brilliant blue G
Brilliant Blue G is used in an ophthalmic solution for staining the internal limiting membrane (ILM) of the eye during ophthalmic procedures.[A188841,A188844] This membrane is thin and translucent, making it difficult to identify during eye surgeries that require high levels of visual accuracy. Brilliant blue G, like its name, imparts...
Approved
Matched Synonyms: … Acid Blue 90 ... Acid Blue 90 …
Matched Description: … [A188841,A188844] This membrane is thin and translucent, making it difficult to identify during eye surgeries …
Matched Categories: … Indicators and Reagents …
Matched Description: … [A188841,A188844] This membrane is thin and translucent, making it difficult to identify during eye surgeries …
Matched Categories: … Indicators and Reagents …
Creatine
An amino acid derivative that occurs in vertebrate tissues and in urine. In muscle tissue, creatine generally occurs as phosphocreatine. Creatine is excreted as creatinine in the urine.
Approved
Investigational
Nutraceutical
Matched Synonyms: … (α-methylguanido)acetic acid ... (alpha-Methylguanido)acetic acid ... alpha-Methylguanidino acetic acid …
Matched Iupac: … 2-(N-methylcarbamimidamido)acetic acid …
Matched Description: … An amino acid derivative that occurs in vertebrate tissues and in urine. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids …
Matched Iupac: … 2-(N-methylcarbamimidamido)acetic acid …
Matched Description: … An amino acid derivative that occurs in vertebrate tissues and in urine. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids …
Dodecyl sulfate
Experimental
Matched Synonyms: … Dodecylsulfuric acid ... Lauryl sulfuric acid ... Sulfuric acid, monododecyl ester …
Matched Iupac: … (dodecyloxy)sulfonic acid …
Matched Categories: … Sulfur Acids ... Sulfonic Acids ... Alkanesulfonic Acids …
Matched Iupac: … (dodecyloxy)sulfonic acid …
Matched Categories: … Sulfur Acids ... Sulfonic Acids ... Alkanesulfonic Acids …
Dexibuprofen
Dexibuprofen, S(+)-ibuprofen, is a non-steroidal anti-inflammatory drug (NSAID). It is a pharmacologically effective enantiomer of racemic ibuprofen that differs in physicochemical properties. It is proposed to be more pharmacologically active and tolerable with a better safety profile than ibuprofen due to higher concentration of active S enantiomer. Dexibuprofen has a...
Approved
Investigational
Matched Synonyms: … (+)-(S)-p-isobutylhydratropic acid ... (2S)-2-(4-isobutylphenyl)propanoic acid ... (S)-α-methyl-4-(2-methylpropyl)benzeneacetic acid …
Matched Iupac: … (2S)-2-[4-(2-methylpropyl)phenyl]propanoic acid …
Matched Description: … It is proposed to be more pharmacologically active and tolerable with a better safety profile than ibuprofen ... the racemic ibuprofen and displays improved oral bioavilability [A19259]. ... Dexibuprofen has a slower dissolution rate in the simulated gastric and enteric juices compared with …
Matched Categories: … Ibuprofen and isomer ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Acids, Carbocyclic ... Carboxylic Acids …
Matched Iupac: … (2S)-2-[4-(2-methylpropyl)phenyl]propanoic acid …
Matched Description: … It is proposed to be more pharmacologically active and tolerable with a better safety profile than ibuprofen ... the racemic ibuprofen and displays improved oral bioavilability [A19259]. ... Dexibuprofen has a slower dissolution rate in the simulated gastric and enteric juices compared with …
Matched Categories: … Ibuprofen and isomer ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Acids, Carbocyclic ... Carboxylic Acids …
Diflunisal
Diflunisal, a salicylate derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with pharmacologic actions similar to other prototypical NSAIAs. Diflunisal possesses anti-inflammatory, analgesic and antipyretic activity. Though its mechanism of action has not been clearly established, most of its actions appear to be associated with inhibition of prostaglandin synthesis via the...
Approved
Investigational
Matched Synonyms: … 5-(2,4-difluorophenyl)salicylic acid ... 2-(hydroxy)-5-(2,4-difluorophenyl)benzoic acid ... 2',4'-difluoro-4-hydroxy-3-biphenylcarboxylic acid …
Matched Iupac: … 2',4'-difluoro-4-hydroxy-[1,1'-biphenyl]-3-carboxylic acid …
Matched Description: … rheumatoid arthritis and osteoarthritis. ... Diflunisal possesses anti-inflammatory, analgesic and antipyretic activity. ... Diflunisal is used to relieve pain accompanied with inflammation and in the symptomatic treatment of …
Matched Categories: … Salicylic Acid and Derivatives …
Matched Iupac: … 2',4'-difluoro-4-hydroxy-[1,1'-biphenyl]-3-carboxylic acid …
Matched Description: … rheumatoid arthritis and osteoarthritis. ... Diflunisal possesses anti-inflammatory, analgesic and antipyretic activity. ... Diflunisal is used to relieve pain accompanied with inflammation and in the symptomatic treatment of …
Matched Categories: … Salicylic Acid and Derivatives …
Thenoyltrifluoroacetone
Thenoyltrifluoroacetone is a chelating agent and inhibitor of cellular respiration.
Experimental
Matched Synonyms: … 1,1,1-Trifluoro-3-(2-thenoyl)acetone …
Matched Description: … Thenoyltrifluoroacetone is a chelating agent and inhibitor of cellular respiration. …
Matched Description: … Thenoyltrifluoroacetone is a chelating agent and inhibitor of cellular respiration. …
(+)-2-(4-biphenyl)propionic acid
Experimental
Matched Synonyms: … (2S)-2-(4-Biphenylyl)propanoic acid ... 2-(1,1'-biphenyl-4-yl)propanoic acid …
Matched Name: … (+)-2-(4-biphenyl)propionic acid …
Matched Iupac: … (2S)-2-{[1,1'-biphenyl]-4-yl}propanoic acid …
Matched Name: … (+)-2-(4-biphenyl)propionic acid …
Matched Iupac: … (2S)-2-{[1,1'-biphenyl]-4-yl}propanoic acid …
Guanosine 3'-monophosphate
Experimental
Matched Synonyms: … Guanylic acid ... 3'-Guanylic acid …
Matched Iupac: … acid ... 2R,3S,4R,5R)-5-(2-amino-6-oxo-6,9-dihydro-1H-purin-9-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]oxy}phosphonic …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Iupac: … acid ... 2R,3S,4R,5R)-5-(2-amino-6-oxo-6,9-dihydro-1H-purin-9-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]oxy}phosphonic …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Propofol Hemisuccinate
Experimental
Matched Synonyms: … Succinic acid monopropofol ester ... Butanedioic acid, 1-(2,6-bis(1-methylethyl)phenyl) ester …
Matched Iupac: … 4-[2,6-bis(propan-2-yl)phenoxy]-4-oxobutanoic acid …
Matched Iupac: … 4-[2,6-bis(propan-2-yl)phenoxy]-4-oxobutanoic acid …
Magnesium ascorbate
Approved
Nutraceutical
Matched Synonyms: … Ascorbic acid, magnesium salt ... L(+)-ascorbic acid magnesium salt …
Matched Categories: … Diet, Food, and Nutrition ... Acids, Acyclic ... Sugar Acids ... Hydroxy Acids ... Carboxylic Acids …
Matched Categories: … Diet, Food, and Nutrition ... Acids, Acyclic ... Sugar Acids ... Hydroxy Acids ... Carboxylic Acids …
Desipramine
Desipramine hydrochloride is a dibenzazepine-derivative tricyclic antidepressant (TCA). TCAs are structurally similar to phenothiazines. They contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individuals, desipramine does not affect mood or arousal, but may cause sedation. In depressed individuals, desipramine exerts a positive...
Approved
Investigational
Matched Description: … TCAs also block histamine-H1 receptors, α1-adrenergic receptors and muscarinic ... Desipramine hydrochloride is a dibenzazepine-derivative tricyclic antidepressant (TCA). ... as amitriptyline and clomipramine. …
Matched Salts name: … Desipramine hydrochloride …
Matched Categories: … Tricyclics and Other Norepinephrine-reuptake Inhibitors ... Histamine Antagonists ... Histamine H1 Antagonists …
Matched Products: … Desipramine Hydrochloride …
Matched Salts name: … Desipramine hydrochloride …
Matched Categories: … Tricyclics and Other Norepinephrine-reuptake Inhibitors ... Histamine Antagonists ... Histamine H1 Antagonists …
Matched Products: … Desipramine Hydrochloride …
Bumetanide
Bumetanide is a sulfamyl diuretic.
Approved
Matched Synonyms: … 3-butylamino-4-(phenoxy)-5-sulfamoylbenzoic acid ... 3-butylamino-4-phenoxy-5-sulfamoyl-benzoic acid ... 3-butylamino-4-phenoxy-5-sulfamoylbenzoic acid …
Matched Iupac: … 3-(butylamino)-4-phenoxy-5-sulfamoylbenzoic acid …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics ... bumetanide and potassium …
Matched Iupac: … 3-(butylamino)-4-phenoxy-5-sulfamoylbenzoic acid …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics ... bumetanide and potassium …
Ornithine
Produced during the urea cycle, ornithine is an amino acid produced from the splitting off of urea from arginine. L-Ornithine allows for the disposal of excess nitrogen and acts as a precursor of citrulline and arginine.
Approved
Nutraceutical
Matched Synonyms: … (S)-2,5-diaminovaleric acid ... (S)-2,5-Diaminopentanoic acid ... (S)-α,δ-diaminovaleric acid …
Matched Iupac: … (2S)-2,5-diaminopentanoic acid …
Matched Description: … L-Ornithine allows for the disposal of excess nitrogen and acts as a precursor of citrulline and arginine ... arginine. ... Produced during the urea cycle, ornithine is an amino acid produced from the splitting off of urea from …
Matched Mixtures name: … GNC PP L-Arginine L-Ornithine Tablet ... PRIMENE 10% AMINO ACID INTRAVENOUS INFUSION …
Matched Salts name: … Ornithine hydrochloride …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Alimentary Tract and Metabolism ... Bile and Liver Therapy ... Amino Acids ... Amino Acids, Basic …
Matched Iupac: … (2S)-2,5-diaminopentanoic acid …
Matched Description: … L-Ornithine allows for the disposal of excess nitrogen and acts as a precursor of citrulline and arginine ... arginine. ... Produced during the urea cycle, ornithine is an amino acid produced from the splitting off of urea from …
Matched Mixtures name: … GNC PP L-Arginine L-Ornithine Tablet ... PRIMENE 10% AMINO ACID INTRAVENOUS INFUSION …
Matched Salts name: … Ornithine hydrochloride …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Alimentary Tract and Metabolism ... Bile and Liver Therapy ... Amino Acids ... Amino Acids, Basic …
Displaying drugs 1701 - 1725 of 3090 in total