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Displaying drugs 1701 - 1725 of 2451 in total
Midecamycin
Midecamycin is a naturally occurring 16-membered macrolide that fits under the category of acetoxy-substituted macrolide antibiotics. In this molecule, an acetoxy group is substituted on the position 9 of the 16-member ring and on position 4 of the terminal sugar. Until 2017, midecamycin was still under the list of approved...
Experimental
Matched Categories: … Cytochrome P-450 CYP3A Inhibitors ... Cytochrome P-450 CYP3A4 Inhibitors ... Cytochrome P-450 Enzyme Inhibitors ... Cytochrome P-450 CYP3A4 Inhibitors (strength unknown) …
Tetrathiomolybdate
Tetrathiomolybdate is an oral, small-molecule, anticopper agent that is highly specific for lowering the levels of free copper in serum. COPREXA has completed pivotal clinical trials for the treatment of neurologic Wilson's disease. It is also developed for fibrotic disorders based upon the rationale that the fibrotic disease process is...
Investigational
Matched Categories: … Enzyme Inhibitors ... Growth Inhibitors ... Adenosine Triphosphatases, antagonists & inhibitors …
Sparsomycin
An antitumor antibiotic produced by Streptomyces sparsogenes. It inhibits protein synthesis in 70S and 80S ribosomal systems. [PubChem]
Experimental
Matched Categories: … Enzyme Inhibitors ... Protein Synthesis Inhibitors …
N-(6-Aminohexyl)-5-Chloro-1-Naphthalenesulfonamide
Experimental
Matched Categories: … Enzyme Inhibitors ... Calcium-Calmodulin-Dependent Protein Kinases, antagonists & inhibitors …
Ranpirnase
Ranpirnase is a ribonuclease enzyme found in Rana pipiens oocytes. It is being studied in the treatment of cancer. It is manufactured by Alfacell Corporation. It is the first ribonuclease to enter cancer clinical trials.
Investigational
Matched Categories: … Enzyme Inhibitors ... Protein Synthesis Inhibitors …
Ranirestat
Ranirestat is a structurally novel and stereospecifically potent aldose reductase (AKR1B; EC 1.1.1.21) inhibitor, which contains a succinimide ring that undergoes ring-opening at physiological pH levels. It has been used in trials studying the treatment of Mild to Moderate Diabetic Sensorimotor Polyneuropathy.
Investigational
Matched Categories: … Enzyme Inhibitors ... Aldehyde Reductase, antagonists & inhibitors …
Isatoic anhydride
Experimental
Matched Categories: … Enzyme Inhibitors ... beta-Lactamase Inhibitors …
Candesartan
Candesartan is an angiotensin-receptor blocker (ARB) that may be used alone or with other agents to treat hypertension. It is available as a prodrug in the form of candesartan cilexetil.
Experimental
Matched Categories: … P-glycoprotein inhibitors ... OATP1B1/SLCO1B1 Inhibitors ... Cytochrome P-450 CYP2C8 Inhibitors ... Cytochrome P-450 CYP2C9 Inhibitors ... Cytochrome P-450 Enzyme Inhibitors …
Ilorasertib
Ilorasertib has been used in trials studying the treatment of Myelodysplasia, Solid Neoplasm, Advanced Cancers, Advanced Solid Tumors, and Acute Myelogenous Leukemia, among others.
Investigational
Matched Categories: … Enzyme Inhibitors ... Protein Kinase Inhibitors …
Gepotidacin
Gepotidacin has been used in trials studying the treatment of Gonorrhea, Infections, Bacterial, and Infections, Respiratory Tract.
Investigational
Matched Categories: … Enzyme Inhibitors ... Topoisomerase Inhibitors …
Ibezapolstat
Ibezapolstat is under investigation in clinical trial NCT04247542 (ACX-362E Ibezapolstat for Oral Treatment of Clostridioides Difficile Infection).
Investigational
Matched Categories: … Enzyme Inhibitors ... Nucleic Acid Synthesis Inhibitors …
Tesmilifene
Tesmilifene is a novel potentiator of chemotherapy which, when added to doxorubicin, achieved an unexpected and very large survival advantage over doxorubicin alone in a randomized trial in advanced breast cancer.
Investigational
Matched Categories: … P-glycoprotein inhibitors ... Cytochrome P-450 CYP3A Inhibitors ... Cytochrome P-450 CYP3A4 Inhibitors ... Cytochrome P-450 Enzyme Inhibitors ... Cytochrome P-450 CYP3A4 Inhibitors (strength unknown) …
Ramiprilat
The active metabolite of the prodrug Ramipril.
Experimental
Matched Categories: … Enzyme Inhibitors ... Protease Inhibitors ... Angiotensin-Converting Enzyme Inhibitors …
Perindoprilat
The active metabolite of the prodrug Perindopril.
Experimental
Matched Categories: … Enzyme Inhibitors ... Protease Inhibitors ... Angiotensin-Converting Enzyme Inhibitors …
2-deoxy-2,3-dehydro-N-acetylneuraminic acid
Experimental
Matched Categories: … Enzyme Inhibitors ... Neuraminidase, antagonists & inhibitors …
E-6005
E6005 has been used in trials studying the treatment of Atopic Dermatitis.
Investigational
Matched Categories: … Phosphodiesterase Inhibitors ... Phosphodiesterase 4 Inhibitors …
Onvansertib
Onvansertib is under investigation in clinical trial NCT03303339 (Onvansertib in Combination With Either Low-dose Cytarabine or Decitabine in Adult Patients With Acute Myeloid Leukemia (AML).).
Investigational
Matched Categories: … Enzyme Inhibitors ... Protein Kinase Inhibitors …
Vorolanib
Vorolanib is under investigation in clinical trial NCT03904719 (CM082 and JS001 in Patients With Advanced Small-cell Lung Cancer (SCLC)).
Investigational
Matched Categories: … Enzyme Inhibitors ... Protein Kinase Inhibitors …
Ecabet
Ecabet is a prescription eye drop for the treatment of dry eye syndrome. Ecabet represents a new class of molecules that increases the quantity and quality of mucin produced by conjunctival goblet cells and corneal epithelia. Mucin is a glycoprotein component of tear film that lubricates while retarding moisture loss...
Investigational
Matched Categories: … Enzyme Inhibitors ... Protease Inhibitors ... Pepsin A, antagonists & inhibitors …
Albinterferon Alfa-2B
Albumin-interferon alpha (Albuferon) is a novel, long-acting form of interferon alpha. Recombinant interferon alpha is approved for the treatment of hepatitis C, hepatitis B, and a broad range of cancers. Human Genome Sciences modified interferon alpha to improve its pharmacological properties by using the company's proprietary albumin fusion technology. Human...
Investigational
Matched Categories: … Cytochrome P-450 CYP1A2 Inhibitors ... Cytochrome P-450 Enzyme Inhibitors ... Cytochrome P-450 CYP1A2 Inhibitors (strength unknown) …
Fosinoprilat
Fosinoprilat is the active phosphinic acid metabolite of prodrug fosinopril, which is activated by esterases in vivo. It binds zinc with phosphinic acid group.
Experimental
Matched Categories: … Enzyme Inhibitors ... Protease Inhibitors ... Angiotensin-Converting Enzyme Inhibitors …
CA-170
CA-170 is a selective, small molecule inhibitor of PD-L1.
Investigational
Matched Categories: … Immune Checkpoint Inhibitors …
Displaying drugs 1701 - 1725 of 2451 in total