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Displaying drugs 151 - 175 of 11601 in total

Bendamustine

Bendamustine is a nitrogen mustard drug which has been used in the treatment of chronic lymphocytic leukemia (CLL) and indolent B-cell non-Hodgkin lymphoma (NHL). Bendamustine is a bifunctional mechlorethamine derivative capable of forming electrophilic alkyl groups that covalently bond to other molecules. Through this function as an alkylating agent, bendamustine...
Approved
Investigational
Matched Description: … Bendamustine is a nitrogen mustard drug which has been used in the treatment of chronic lymphocytic leukemia ... Bendamustine is a bifunctional mechlorethamine derivative capable of forming electrophilic alkyl groups …
Matched Categories: … P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index …
Matched Products: … GENSTINA® POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION INYECTABLE …

Reviparin

Reviparin is a low molecular weight heparin which seems to have a better safety profile than unfractionated heparin. It is prepared from porcine intestinal mucosa by nitrous acid depolymerization. Reviparin has a molecular weight of 3.9 kDa. It was developed by Abbott laboratories and in 2009, reviparin presented an orphan...
Approved
Investigational
Matched Description: … Reviparin is a low molecular weight heparin which seems to have a better safety profile than unfractionated ... Reviparin has a molecular weight of 3.9 kDa. …
Matched Products: … CLIVARIN 5726 IE A XA/ML ... CLIVARODI 17178 A XA/ML …

Dihydro-alpha-ergocryptine

Alpha-dihydroergocryptine is usually referred to the mixture of the alpha and beta dihydroergocryptine. These two compounds are differentiated in the position of a methyl group. This structural difference is due to a proteinogenic amino acid replacement from leucine to isoleucine. Both compounds are hydrogenated ergot derivatives. Alpha-dihydroergocryptine approved drug product...
Approved
Matched Description: … These two compounds are differentiated in the position of a methyl group. ... Alpha-dihydroergocryptine approved drug product is as a part of an ergoloid mixture. ... This structural difference is due to a proteinogenic amino acid replacement from leucine to isoleucine …

Thiosulfuric acid

Thiosulfuric acid is available in its salt forms sodium thiosulfate and sodium thiosulfate pentahydrate. Sodium thiosulfate is part of the World Health Organization’s list of essential medicines, and it has a variety of industrial uses, including food preservative, water de-chlorinator and paper pulp bleaching agent. Sodium thiosulfate is rapidly degraded...
Approved
Investigational
Matched Description: … Sodium thiosulfate is part of the World Health Organization’s list of essential medicines, and it has a ... [L43337] When administered 6 hours after cisplatin chemotherapy, Sodium thiosulfate leads to a lower ... cyanide poisoning[L310,L43332,A252832] and it is frequently used in conjunction with sodium nitrite (a …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Pantothenic acid

Pantothenic acid, also called pantothenate or vitamin B5 (a B vitamin), is a water-soluble vitamin discovered by Roger J. Williams in 1919. For many animals, pantothenic acid is an essential nutrient as it is required to synthesize coenzyme-A (CoA), as well as to synthesize and metabolize proteins, carbohydrates, and fats....
Approved
Nutraceutical
Vet approved
Matched Description: … Pantothenic acid, also called pantothenate or vitamin B5 (a B vitamin), is a water-soluble vitamin discovered ... For many animals, pantothenic acid is an essential nutrient as it is required to synthesize coenzyme-A …
Matched Mixtures name: … Toni Com Liq ... One A Day Tab ... ONE A DAY TABLET …

Carbon monoxide

Carbon monoxide (CO) is a colorless, odorless, and tasteless gas that has a slightly lower density than air. It is toxic to hemoglobin utilizing animals (including humans), when encountered in concentrations above about 35 ppm, although it is also formed in normal animal metabolism in low quantities, and is thought...
Approved
Investigational
Matched Description: … Carbon monoxide (CO) is a colorless, odorless, and tasteless gas that has a slightly lower density than ... Carbon monoxide (CO), is a ubiquitous environmental product of organic combustion, which is also formed ... The European Union has banned the use of carbon monoxide as a color stabilizer in meat and fish. …

Apraclonidine

Apraclonidine, also known as iopidine, is a sympathomimetic used in glaucoma therapy. It is an alpha2-adrenergic agonist.
Approved
Matched Description: … Apraclonidine, also known as iopidine, is a sympathomimetic used in glaucoma therapy. …

Argatroban

Argatroban is a direct, selective thrombin inhibitor. The American College of Cardiologists (ACC) recommend using bivalirudin or argatroban in patients who have had, or at risk for, heparin induced thrombocytopenia (HIT) and are undergoing percutaneous coronary intervention. Argatroban is a non-heparin anticoagulant shown to both normalize platelet count in patients...
Approved
Investigational
Matched Description: … Argatroban is a direct, selective thrombin inhibitor. ... Argatroban is a non-heparin anticoagulant shown to both normalize platelet count in patients with HIT ... Parental anticoagulants must be stopped and a baseline activated partial thromboplastin time must be …
Matched Categories: … Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A5 Substrates with a Narrow Therapeutic Index …

Isoniazid

Antibacterial agent used primarily as a tuberculostatic. It remains the treatment of choice for tuberculosis.
Approved
Investigational
Matched Description: … Antibacterial agent used primarily as a tuberculostatic. …

Ioxaglic acid

Ioxaglic acid is marketed as Hexabrix. This drug is an ionic tri-iodinated benzoate used as a low-osmolality contrast agent during diagnostic imaging procedures. Like other organic iodine compounds, ioxaglic acid blocks x-rays and is opaque in its appearance on x-ray film, improving the visualization of important structures and organs during...
Approved
Investigational
Matched Description: … This drug is an ionic tri-iodinated benzoate used as a low-osmolality contrast agent during diagnostic ... Ioxaglic acid has a low osmolarity and is associated with fewer side effects compared to older contrast …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Ethanol

A clear, colorless liquid rapidly absorbed from the gastrointestinal tract and distributed throughout the body. It has bactericidal activity and is used often as a topical disinfectant. It is widely used as a solvent and preservative in pharmaceutical preparations as well as serving as the primary ingredient in alcoholic beverages.
Approved
Matched Description: … It has bactericidal activity and is used often as a topical disinfectant. ... A clear, colorless liquid rapidly absorbed from the gastrointestinal tract and distributed throughout ... It is widely used as a solvent and preservative in pharmaceutical preparations as well as serving as …
Matched Mixtures name: … Nox-A-Sting ... Soothe-A-sting ... Soothe-A-Sting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … Mavs Com Hand Sanitizer ... TongYi CleanGuard In-car Atomization Bactericide ... Recens A …

Abemaciclib

Abemaciclib is an antitumor agent and dual inhibitor of cyclin-dependent kinases 4 (CDK4) and 6 (CDK6) that are involved in the cell cycle and promotion of cancer cell growth in case of unregulated activity. On September 28, 2017, FDA granted approval of abemaciclib treatment under the market name Verzenio for...
Approved
Investigational
Matched Categories: … MATE 1 Substrates with a Narrow Therapeutic Index ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …

Patent Blue

Patent blue is aniline dye and it is one of the most common dyes used. It is a sodium or calcium salt of diethylammonium hydroxide inner salt. It has the chemical designation of (4-(alpha-(p-(diethylamino)phenyl)-2,4-disulfobenzylidene)-2,5-cyclohexadiene-1-ylidene)diethylammonium hydroxide. Patent blue was developed by Guerbet and approved by Health Canada on December 31, 1979....
Approved
Matched Description: … [A32573] It is a sodium or calcium salt of diethylammonium hydroxide inner salt. …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Larotrectinib

Larotrectinib is an orally administered inhibitor of tropomyosin receptor kinase (Trk), a receptor tyrosine kinase activated by neurotrophins which is mutated in a variety of cancer cell types and plays an important role in tumor cell growth and survival. Upon administration, larotrectinib binds to Trk, thereby preventing neurotrophin-Trk interaction and...
Approved
Investigational
Matched Iupac: … (3S)-N-{5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidin-3-yl}-3-hydroxypyrrolidine …
Matched Description: … Larotrectinib is an orally administered inhibitor of tropomyosin receptor kinase (Trk), a receptor tyrosine ... kinase activated by neurotrophins which is mutated in a variety of cancer cell types and plays an important …

Zinc gluconate

Zinc gluconate is a zinc salt of gluconic acid comprised of two gluconic acid molecules for each zinc cation (2+). Zinc gluconate is a generally recognized as safe (GRAS) substance by FDA . It is available as a trace mineral supplement and over the counter as a lozenge form for...
Approved
Vet approved
Matched Description: … It is available as a trace mineral supplement and over the counter as a lozenge form for a reduced duration ... Zinc gluconate is a generally recognized as safe (GRAS) substance by FDA [L2081]. ... Zinc gluconate is a zinc salt of gluconic acid comprised of two gluconic acid molecules for each zinc …
Matched Mixtures name: … A+ Zinc Tab ... One A Day With Non-medicinal Echinacea ... Evc Liquid Vitamins A,c,b6 With Beta Caro&zn …
Matched Products: … ZINC INJECTABLE A 1mg/ml, solution injectable pour perfusion …

Glutamic acid

A peptide that is a homopolymer of glutamic acid.
Approved
Nutraceutical
Matched Description: … A peptide that is a homopolymer of glutamic acid. …

Ergocalciferol

Ergocalciferol is an inactivated vitamin D analog. It is synthesized by some plants in the presence of UVB light. The production of ergocalciferol was prompted by the identification of dietary deficiency, more specifically vitamin D, as the main causative factor for the development of rickets. Ergocalciferol was isolated for the...
Approved
Nutraceutical
Matched Description: … double bond between C22 and C23 and the presence of a methyl group at C24. ... considered the first vitamin D analog and is differentiated from [cholecalciferol] by the presence of a …
Matched Mixtures name: … One A Day Tab ... Aquasol A & D Drops ... Complete One A Day Tab …

Leuprolide

Leuprolide is a synthetic 9-residue peptide analogue of gonadotropin-releasing hormone (GnRH). Unlike the endogenous decapeptide GnRH, leuprolide contains a single D-amino acid (D-leucyl) residue, which helps to increase its circulating half-life from three to four minutes to approximately three hours. As a GnRH mimic, leuprolide is capable of binding to...
Approved
Investigational
Matched Description: … Leuprolide is a synthetic 9-residue peptide analogue of gonadotropin-releasing hormone (GnRH). ... Unlike the endogenous decapeptide GnRH, leuprolide contains a single D-amino acid (D-leucyl) residue, ... [A203222] As a GnRH mimic, leuprolide is capable of binding to the GnRH receptor (GnRHR) and inducing …
Matched Products: … LUPRON ® DEPOT 11.25 MG POLVO LIOFILIOZADO PARA RECONSTITUIR A SUSPENSIÓN INYECTABLE …

Edetic acid

A chelating agent (chelating agents) that sequesters a variety of polyvalent cations. It is used in pharmaceutical manufacturing and as a food additive.
Approved
Vet approved
Matched Description: … A chelating agent (chelating agents) that sequesters a variety of polyvalent cations. ... It is used in pharmaceutical manufacturing and as a food additive. …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Omega-3-carboxylic acids

The omega-3 carboxylic acid (OM3-CA) is a new formulation of omega-3 fatty acids that present an enhanced bioavailability in the treatment of dyslipidemia. The increased bioavailability is explained because OM3-CA is found in a form of polyunsaturated free fatty acids as opposed to other products whose form is as ethyl...
Approved
Investigational
Matched Description: … acid as the most abundant species found in a proportion of 55% and 20% respectively. ... The omega-3 carboxylic acid (OM3-CA) is a new formulation of omega-3 fatty acids that present an enhanced ... The increased bioavailability is explained because OM3-CA is found in a form of polyunsaturated free …

D-alpha-Tocopherol acetate

Alpha-tocopherol is the primary form of vitamin E that is preferentially used by the human body to meet appropriate dietary requirements. In particular, the RRR-alpha-tocopherol (or sometimes called the d-alpha-tocopherol stereoisomer) stereoisomer is considered the natural formation of alpha-tocopherol and generally exhibits the greatest bioavailability out of all of the...
Approved
Nutraceutical
Vet approved
Matched Description: … used as a food additive when needed [A32451]. ... subsequently most commonly indicated for dietary supplementation in individuals who may demonstrate a ... is naturally found in various foods, added to others, or used in commercially available products as a …
Matched Mixtures name: … Vitamin A C E W.niacinam.beta Car.and Min. …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Imipramine

Imipramine, the prototypical tricyclic antidepressant (TCA), is a dibenzazepine-derivative TCA. TCAs are structurally similar to phenothiazines. They contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individuals, imipramine does not affect mood or arousal, but may cause sedation. In depressed individuals, imipramine exerts...
Approved
Matched Description: … In depressed individuals, imipramine exerts a positive effect on mood. ... Imipramine, the prototypical tricyclic antidepressant (TCA), is a dibenzazepine-derivative TCA. ... They contain a tricyclic ring system with an alkyl amine substituent on the central ring. …
Matched Categories: … P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2B6 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C18 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic Index …

Gadobenic acid

Gadobenic acid, usually available in the salt form gadobenate dimeglumine, is a linear MRI gadolinium-based contrast agent (GBCA) used primarily for MR imaging of the liver. It differs from other GBCAs due to the benzene ring that confers weak protein binding, thus leading to an increased R1 and R2 relaxivity....
Approved
Investigational
Matched Description: … Gadobenic acid, usually available in the salt form gadobenate dimeglumine, is a linear MRI gadolinium-based ... dimeglumine is specifically taken up by hepatocytes and excreted through the biliary system, it is a …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Quinidine

Quinidine is a D-isomer of quinine present in the bark of the Cinchona tree and similar plant species. This alkaloid was first described in 1848 and has a long history as an antiarrhythmic medication.[A38016,A250050] Quinidine is considered the first antiarrhythmic drug (class Ia) and is moderately efficacious in the acute...
Approved
Investigational
Matched Description: … Quinidine is a D-isomer of [quinine] present in the bark of the Cinchona tree and similar plant species ... This alkaloid was first described in 1848 and has a long history as an antiarrhythmic medication. ... A phenomenon known as “quinidine syncope” was first described in the 1950s, characterized by syncopal …
Matched Categories: … P-glycoprotein substrates with a Narrow Therapeutic Index ... Compounds used in a research, industrial, or household setting ... Cytochrome P-450 CYP2C9 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2E1 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …

Selenious acid

Selenious acid is the acid form of sodium selenite, a form of selenium . Selenium is an essential trace element and antioxidant. It is a cofactor metabolic enzyme regulation. It also plays an important role in maintaining the general health of tissue and muscle and has antioxidant properties. Selenium is...
Approved
Investigational
Matched Description: … It is a cofactor metabolic enzyme regulation. ... Selenious acid is the acid form of sodium selenite, a form of selenium [L1910]. ... Selenium is a component of glutathione peroxidase enzyme, which protects cell components from oxidative …
Displaying drugs 151 - 175 of 11601 in total