Displaying drugs 151 - 175 of 13294 in total
Cilostazol
Cilostazol is a quinolinone derivative and antiplatelet agent with vasodilating properties that has been used in the symptomatic treatment of intermittent claudication in patients with peripheral ischaemia. It is marketed under the brand name Pletal by Otsuka Pharmaceutical Co.. Cilostazol works by inhibiting both primary and secondary aggregation and reducing...
Approved
Investigational
Matched Synonyms: … 6-(4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy)-3,4-dihydrocarbostyril ... 3,4-dihydro-6-(4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy)-2(1H)-quinolinone ... 6-(4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy)-3,4-dihydro-2(1H)-quinolinone …
Matched Iupac: … 6-[4-(1-cyclohexyl-1H-1,2,3,4-tetrazol-5-yl)butoxy]-1,2,3,4-tetrahydroquinolin-2-one …
Matched Description: … Cilostazol is a quinolinone derivative and antiplatelet agent with vasodilating properties that has been …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Compounds used in a research, industrial, or household setting …
Matched Iupac: … 6-[4-(1-cyclohexyl-1H-1,2,3,4-tetrazol-5-yl)butoxy]-1,2,3,4-tetrahydroquinolin-2-one …
Matched Description: … Cilostazol is a quinolinone derivative and antiplatelet agent with vasodilating properties that has been …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Compounds used in a research, industrial, or household setting …
Cefmenoxime
Cefmenoxime is a novel broad-spectrum and third-generation cephalosporin antibiotic that is typically used in the treatment of female gynecologic and obstetric infections. It is reported to exhibit high activity against a wide variety of gram-positive and gram-negative bacteria.
Approved
Matched Synonyms: … )-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-en-2-carbonsaeure ... ]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid ... (6R,7R)-7-((Z)-2-(2-Amino-4-thiazolyl)-2-methoxyiminoacetamido)-3-((1-methyl-1H-5-tetraazolylthio)methyl …
Matched Iupac: … -5-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid ... (6R,7R)-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-3-{[(1-methyl-1H-1,2,3,4-tetrazol …
Matched Description: … Cefmenoxime is a novel broad-spectrum and third-generation cephalosporin antibiotic that is typically ... It is reported to exhibit high activity against a wide variety of gram-positive and gram-negative bacteria …
Matched Iupac: … -5-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid ... (6R,7R)-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-3-{[(1-methyl-1H-1,2,3,4-tetrazol …
Matched Description: … Cefmenoxime is a novel broad-spectrum and third-generation cephalosporin antibiotic that is typically ... It is reported to exhibit high activity against a wide variety of gram-positive and gram-negative bacteria …
Cefamandole
Cefamandole is also known as cephamandole. It is a parenterally administered broad-spectrum cephalosporin antibiotic. It is generally formulated as a formate ester, cefamandole nafate. It is no longer marketed in the United States.
Approved
Experimental
Matched Synonyms: … (6R,7R)-7-(R)-Mandelamido-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0 ... -5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid ... (6R,7R)-7-{[(2R)-2-hydroxy-2-phenylacetyl]amino}-3-{[(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl}-8-oxo …
Matched Iupac: … 8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid ... (6R,7R)-7-[(2R)-2-hydroxy-2-phenylacetamido]-3-{[(1-methyl-1H-1,2,3,4-tetrazol-5-yl)sulfanyl]methyl}- …
Matched Description: … It is generally formulated as a formate ester, [cefamandole nafate]. ... It is a parenterally administered broad-spectrum cephalosporin antibiotic. …
Matched Iupac: … 8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid ... (6R,7R)-7-[(2R)-2-hydroxy-2-phenylacetamido]-3-{[(1-methyl-1H-1,2,3,4-tetrazol-5-yl)sulfanyl]methyl}- …
Matched Description: … It is generally formulated as a formate ester, [cefamandole nafate]. ... It is a parenterally administered broad-spectrum cephalosporin antibiotic. …
Florbetaben F-18
Florbetaben is a fluorine-18 (18F)-labeled stilbene derivative used for Positron Emission Tomography (PET) imaging of the brain. It is used for the non-invasive detection of the density of ß-amyloid neuritic plaques in the brain of adult patients with cognitive impairment.
Approved
Matched Synonyms: … 4-((1E)-2-(4-(2-(2-(2-((SUP 18(F))FLUOROETHOXY)ETHOXY)ETHOXY)PHENYL)ETH-1-EN-1-YL)-N-METHYLANILINE …
Matched Description: … Florbetaben is a fluorine-18 (18F)-labeled stilbene derivative used for Positron Emission Tomography …
Matched Description: … Florbetaben is a fluorine-18 (18F)-labeled stilbene derivative used for Positron Emission Tomography …
Eptotermin alfa
A bone morphogenetic protein that is widely expressed during EMBRYONIC DEVELOPMENT. It is both a potent osteogenic factor and a specific regulator of nephrogenesis. Eptotermin alfa is an ingredient in the EMA-withdrawn product Osigraft.
Approved
Investigational
Withdrawn
Matched Synonyms: … OP-1 ... Osteogenic protein 1 …
Matched Description: … It is both a potent osteogenic factor and a specific regulator of nephrogenesis. ... A bone morphogenetic protein that is widely expressed during EMBRYONIC DEVELOPMENT. …
Matched Description: … It is both a potent osteogenic factor and a specific regulator of nephrogenesis. ... A bone morphogenetic protein that is widely expressed during EMBRYONIC DEVELOPMENT. …
Levacetylmethadol
Levacetylmethadol is a narcotic analgesic with a long onset and duration of action. It is used mainly in the treatment of narcotic dependence.
Levacetylmethadol was withdrawn from use in the European Union due to its high risk of QT interval prolongation. The production of levacetylmethadol in the US has ceased...
Approved
Investigational
Withdrawn
Matched Synonyms: … 1-alpha-Acetylmethadol ... (1S,4S)-4-(dimethylamino)-1-ethyl-2,2-diphenylpentyl acetate …
Matched Description: … Levacetylmethadol is a narcotic analgesic with a long onset and duration of action. …
Matched Categories: … Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A7 Substrates with a Narrow Therapeutic Index …
Matched Description: … Levacetylmethadol is a narcotic analgesic with a long onset and duration of action. …
Matched Categories: … Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A7 Substrates with a Narrow Therapeutic Index …
Dacarbazine
An antineoplastic agent. It has significant activity against melanomas. (from Martindale, The Extra Pharmacopoeia, 31st ed, p564). Dacarbazine with Oblimersen is in clinical trials for the treatment of malignant melanoma.
Approved
Investigational
Matched Synonyms: … 4-(3,3-dimethyl-1-triazeno)imidazole-5-carboxamide ... 5-(3,3-dimethyl-1-triazeno)imidazole-4-carboxamide ... 4-(5)-(3,3-dimethyl-1-triazeno)imidazole-5(4)-carboxamide …
Matched Iupac: … 5-[(1E)-3,3-dimethyltriaz-1-en-1-yl]-1H-imidazole-4-carboxamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2E1 Substrates with a Narrow Therapeutic Index …
Matched Products: … TREXTECH® 200 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCIÓN INYECTABLE …
Matched Iupac: … 5-[(1E)-3,3-dimethyltriaz-1-en-1-yl]-1H-imidazole-4-carboxamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2E1 Substrates with a Narrow Therapeutic Index …
Matched Products: … TREXTECH® 200 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCIÓN INYECTABLE …
Sufentanil
Sufentanil is an opioid analgesic that is used as an adjunct in anesthesia, in balanced anesthesia, and as a primary anesthetic agent. It is administered by the intravenous, epidural and sublingual routes.
Also known as Dsuvia, the sublingual form is used for the management of acute pain in adults that...
Approved
Investigational
Matched Synonyms: … N-(4-(Methoxymethyl)-1-(2-(2-thienyl)ethyl)-4-piperidyl)propionanilide ... N-(4-(Methoxymethyl)-1-(2-(2-thienyl)ethyl)-4-piperidinyl)-N-phenylpropanamide …
Matched Iupac: … N-[4-(methoxymethyl)-1-[2-(thiophen-2-yl)ethyl]piperidin-4-yl]-N-phenylpropanamide …
Matched Description: … Sufentanil is an opioid analgesic that is used as an adjunct in anesthesia, in balanced anesthesia, and as a ... This route of administration is intended to be a simple, effective, non-invasive analgesic option to …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … N-[4-(methoxymethyl)-1-[2-(thiophen-2-yl)ethyl]piperidin-4-yl]-N-phenylpropanamide …
Matched Description: … Sufentanil is an opioid analgesic that is used as an adjunct in anesthesia, in balanced anesthesia, and as a ... This route of administration is intended to be a simple, effective, non-invasive analgesic option to …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Oteseconazole
Oteseconazole is an azole metalloenzyme inhibitor that targets fungal CYP51. CYP51, also known as 14α demethylase, participates in the formation of ergosterol, a compound that plays a vital role in the integrity of cell membranes.[L41635,A247020] By binding and inhibiting CYP51, oteseconazole is active against most microorganisms associated with recurrent vulvovaginal...
Approved
Investigational
Matched Synonyms: … (R)-2-(2,4-difluorophenyl)-1,1-difluoro-3-(1H-tetrazol-1-yl)-1(5-(4-(2,2,2-trifluoroethoxy)phenyl)pyridin ... 2-Pyridineethanol, α-(2,4difluorophenyl)-β β-difluoro- α-(1H-tetrazol-1-ylmethyl)-5-(4-(2,2,2-trifluoroethoxy …
Matched Iupac: … (2R)-2-(2,4-difluorophenyl)-1,1-difluoro-3-(1H-1,2,3,4-tetrazol-1-yl)-1-{5-[4-(2,2,2-trifluoroethoxy) …
Matched Description: … that plays a vital role in the integrity of cell membranes. ... [L41635] CYP51, also known as 14α demethylase, participates in the formation of ergosterol, a compound ... [L41635] Unlike previous-generation azole antifungals, oteseconazole has a high selectivity for CYP51 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … (2R)-2-(2,4-difluorophenyl)-1,1-difluoro-3-(1H-1,2,3,4-tetrazol-1-yl)-1-{5-[4-(2,2,2-trifluoroethoxy) …
Matched Description: … that plays a vital role in the integrity of cell membranes. ... [L41635] CYP51, also known as 14α demethylase, participates in the formation of ergosterol, a compound ... [L41635] Unlike previous-generation azole antifungals, oteseconazole has a high selectivity for CYP51 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Practolol
A beta-adrenergic antagonist that has been used in the emergency treatment of cardiac arrhythmias.
Approved
Matched Synonyms: … 1-(4-acetamidophenoxy)-3-isopropylamino-2-propanol ... N-(4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)phenyl)acetamide …
Matched Description: … A beta-adrenergic antagonist that has been used in the emergency treatment of cardiac arrhythmias. …
Matched Categories: … Adrenergic beta-1 Receptor Antagonists …
Matched Description: … A beta-adrenergic antagonist that has been used in the emergency treatment of cardiac arrhythmias. …
Matched Categories: … Adrenergic beta-1 Receptor Antagonists …
Ceftibuten
Ceftibuten is a third-generation cephalosporin antibiotic that is orally-administered. It is typically used to treat acute bacterial exacerbations of chronic bronchitis (ABECB), acute bacterial otitis media, pharyngitis, and tonsilitis.
Approved
Investigational
Matched Synonyms: … (+)-(6R,7R)-7-((Z)-2-(2-amino-4-thiazolyl)-4-carboxycrotonamido)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct- …
Matched Iupac: … (6R,7R)-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-4-carboxybut-2-enamido]-8-oxo-5-thia-1-azabicyclo[4.2.0] …
Matched Description: … Ceftibuten is a third-generation cephalosporin antibiotic that is orally-administered. …
Matched Mixtures name: … BUCEF PLUS 180/62.5 MG TOZ ICEREN SASE, 20 ADET ... BUCEF PLUS 90/62.5 MG TOZ ICEREN SASE, 20 ADET ... WINCEF PLUS 400/125 MG FILM KAPLI TABLET, 20 ADET …
Matched Products: … BUCEF 180 MG SASE, 20 ADET ... BUCEF 90 MG SASE, 20 ADET ... BUCEF 200 MG KAPSUL, 20 ADET …
Matched Iupac: … (6R,7R)-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-4-carboxybut-2-enamido]-8-oxo-5-thia-1-azabicyclo[4.2.0] …
Matched Description: … Ceftibuten is a third-generation cephalosporin antibiotic that is orally-administered. …
Matched Mixtures name: … BUCEF PLUS 180/62.5 MG TOZ ICEREN SASE, 20 ADET ... BUCEF PLUS 90/62.5 MG TOZ ICEREN SASE, 20 ADET ... WINCEF PLUS 400/125 MG FILM KAPLI TABLET, 20 ADET …
Matched Products: … BUCEF 180 MG SASE, 20 ADET ... BUCEF 90 MG SASE, 20 ADET ... BUCEF 200 MG KAPSUL, 20 ADET …
Rifapentine
Rifapentine is an antibiotic drug used in the treatment of tuberculosis. It inhibits DNA-dependent RNA polymerase activity in susceptible cells. Specifically, it interacts with bacterial RNA polymerase but does not inhibit the mammalian enzyme.
Approved
Investigational
Matched Synonyms: … 3-(((4-Cyclopentyl-1-piperazinyl)imino)methyl)rifamycin …
Matched Iupac: … (7S,9E,11S,12R,13S,14R,15R,16R,17S,18S,19E,21Z)-26-[(E)-[(4-cyclopentylpiperazin-1-yl)imino]methyl]-2,15,17,27,29 ... 3,7,12,14,16,18,22-heptamethyl-6,23-dioxo-8,30-dioxa-24-azatetracyclo[23.3.1.1^{4,7}.0^{5,28}]triaconta-1( …
Matched Iupac: … (7S,9E,11S,12R,13S,14R,15R,16R,17S,18S,19E,21Z)-26-[(E)-[(4-cyclopentylpiperazin-1-yl)imino]methyl]-2,15,17,27,29 ... 3,7,12,14,16,18,22-heptamethyl-6,23-dioxo-8,30-dioxa-24-azatetracyclo[23.3.1.1^{4,7}.0^{5,28}]triaconta-1( …
Azlocillin
Azlocillin is a semisynthetic ampicillin-derived acylureido penicillin.
Approved
Matched Synonyms: … }-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid ... (2S,5R,6R)-3,3-dimethyl-7-oxo-6-{[(2R)-2-{[(2-oxoimidazolidin-1-yl)carbonyl]amino}-2-phenylacetyl]amino …
Matched Iupac: … -1-azabicyclo[3.2.0]heptane-2-carboxylic acid ... (2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(2R)-2-[(2-oxoimidazolidine-1-carbonyl)amino]-2-phenylacetamido]-4-thia …
Matched Description: … Azlocillin is a semisynthetic ampicillin-derived acylureido penicillin. …
Matched Iupac: … -1-azabicyclo[3.2.0]heptane-2-carboxylic acid ... (2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(2R)-2-[(2-oxoimidazolidine-1-carbonyl)amino]-2-phenylacetamido]-4-thia …
Matched Description: … Azlocillin is a semisynthetic ampicillin-derived acylureido penicillin. …
Naloxone
Naloxone is an opioid antagonist medication used to block or reverse the effects of opioid drugs, particularly within the setting of drug overdoses which are rapidly becoming a leading cause of death worldwide. More specifically, naloxone has a high affinity for μ-opioid receptors, where it acts as an inverse agonist,...
Approved
Vet approved
Matched Synonyms: … 1-N-Allyl-14-hydroxynordihydromorphinone …
Matched Iupac: … (1S,5R,13R,17S)-10,17-dihydroxy-4-(prop-2-en-1-yl)-12-oxa-4-azapentacyclo[9.6.1.0^{1,13}.0^{5,17}.0^{ …
Matched Description: … as alcohol swabs, syringes, a rescue breathing mask, and instructions for use. ... effects of opioid drugs, particularly within the setting of drug overdoses which are rapidly becoming a ... [A234594] More specifically, naloxone has a high affinity for μ-opioid receptors, where it acts as an …
Matched Mixtures name: … Bupensan Duo 4 mg/1 mg-Sublingualtabletten ... OXYCODON COMP 1A 20/10MG ... OXYCODON COMP 1A 20/10MG …
Matched Iupac: … (1S,5R,13R,17S)-10,17-dihydroxy-4-(prop-2-en-1-yl)-12-oxa-4-azapentacyclo[9.6.1.0^{1,13}.0^{5,17}.0^{ …
Matched Description: … as alcohol swabs, syringes, a rescue breathing mask, and instructions for use. ... effects of opioid drugs, particularly within the setting of drug overdoses which are rapidly becoming a ... [A234594] More specifically, naloxone has a high affinity for μ-opioid receptors, where it acts as an …
Matched Mixtures name: … Bupensan Duo 4 mg/1 mg-Sublingualtabletten ... OXYCODON COMP 1A 20/10MG ... OXYCODON COMP 1A 20/10MG …
Acamprosate
Alcohol use disorder is responsible for a large worldwide burden of morbidity, premature mortality, and economic consequences resulting from accidents, violence, incarceration, decreased productivity, and increased healthcare spending. Acamprosate, also known by the brand name Campral, is a drug used for the maintenance of alcohol abstinence. It is a structural...
Approved
Investigational
Matched Synonyms: … 3-Acetamido-1-propanesulfonic acid …
Matched Iupac: … 3-acetamidopropane-1-sulfonic acid …
Matched Description: … It is a structural analogue of the neurotransmitter γ-aminobutyric acid (GABA). ... Alcohol use disorder is responsible for a large worldwide burden of morbidity, premature mortality, and ... [A229073] Acamprosate, also known by the brand name Campral, is a drug used for the maintenance of …
Matched Iupac: … 3-acetamidopropane-1-sulfonic acid …
Matched Description: … It is a structural analogue of the neurotransmitter γ-aminobutyric acid (GABA). ... Alcohol use disorder is responsible for a large worldwide burden of morbidity, premature mortality, and ... [A229073] Acamprosate, also known by the brand name Campral, is a drug used for the maintenance of …
Stavudine
A dideoxynucleoside analog that inhibits reverse transcriptase and has in vitro activity against HIV.
Approved
Investigational
Matched Synonyms: … 1-(2,3-Dideoxy-beta-D-glycero-pent-2-enofuranosyl)thymine …
Matched Iupac: … 1-[(2R,5S)-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl]-5-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione …
Matched Description: … A dideoxynucleoside analog that inhibits reverse transcriptase and has in vitro activity against HIV. …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … STAVIRCAPSULAS 20 MG. ... ESTAVUDINA CÁPSULAS 20 MG …
Matched Iupac: … 1-[(2R,5S)-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl]-5-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione …
Matched Description: … A dideoxynucleoside analog that inhibits reverse transcriptase and has in vitro activity against HIV. …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … STAVIRCAPSULAS 20 MG. ... ESTAVUDINA CÁPSULAS 20 MG …
Gemcitabine
Gemcitabine is a nucleoside analog and a chemotherapeutic agent. It was originally investigated for its antiviral effects, but it is now used as an anticancer therapy for various cancers. Gemcitabine is a cytidine analog with two fluorine atoms replacing the hydroxyl on the ribose. As a prodrug, gemcitabine is transformed...
Approved
Matched Synonyms: … 4-amino-1-((2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)-tetrahydrofuran-2-yl)pyrimidin-2(1H)-one …
Matched Iupac: … 4-amino-1-[(2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydropyrimidin-2-one …
Matched Description: … Gemcitabine is a nucleoside analog and a chemotherapeutic agent. ... [A233145] As a prodrug, gemcitabine is transformed into its active metabolites that work by replacing ... [A233135] Gemcitabine is a cytidine analog with two fluorine atoms replacing the hydroxyl on the ribose …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... P-glycoprotein substrates with a Narrow Therapeutic Index …
Matched Products: … GEMTU 2000 MG/20 ML KONSANTRE INFÜZYON ÇÖZELTISI ,FLAKON, 1 ADET ... PAMIGEN® 200MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCIONINYECTABLE ... VIRULIZIN® 1G POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCIÓN INYECTABLE …
Matched Iupac: … 4-amino-1-[(2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydropyrimidin-2-one …
Matched Description: … Gemcitabine is a nucleoside analog and a chemotherapeutic agent. ... [A233145] As a prodrug, gemcitabine is transformed into its active metabolites that work by replacing ... [A233135] Gemcitabine is a cytidine analog with two fluorine atoms replacing the hydroxyl on the ribose …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... P-glycoprotein substrates with a Narrow Therapeutic Index …
Matched Products: … GEMTU 2000 MG/20 ML KONSANTRE INFÜZYON ÇÖZELTISI ,FLAKON, 1 ADET ... PAMIGEN® 200MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCIONINYECTABLE ... VIRULIZIN® 1G POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCIÓN INYECTABLE …
Decitabine
Myelodysplastic syndromes (MDS) are a heterogeneous group of hematopoietic neoplasms with variable underlying etiology and presentation, including neutropenia and thrombocytopenia. Further mutations leading to increased proliferation of cancerous cells can eventually lead to secondary acute myeloid leukemia, which has a poor prognosis.[A215082, A215092] Among treatment options, nucleoside analogues such as...
Approved
Investigational
Matched Synonyms: … 4-amino-1-(2-deoxy-β-D-erythro-pentofuranosyl)-s-triazin-2(1H)-one …
Matched Iupac: … 4-amino-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydro-1,3,5-triazin-2-one …
Matched Description: … Myelodysplastic syndromes (MDS) are a heterogeneous group of hematopoietic neoplasms with variable underlying ... proliferation of cancerous cells can eventually lead to secondary acute myeloid leukemia, which has a …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … DESİTAB 50 MG IV ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMADA KULLANILACAK KONSANTRE İÇİN TOZ, 1 ADET ... DESİTU 50 MG İNFÜZYONLUK ÇÖZELTİ HAZIRLAMADA KULLANILACAK KONSANTRE İÇİN TOZ, 1 ADET ... DESİBEM 50 MG İNFÜZYONLUK ÇÖZELTİ HAZIRLAMADA KULLANILACAK KONSANTRE İÇİN TOZ, 1 ADET …
Matched Iupac: … 4-amino-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydro-1,3,5-triazin-2-one …
Matched Description: … Myelodysplastic syndromes (MDS) are a heterogeneous group of hematopoietic neoplasms with variable underlying ... proliferation of cancerous cells can eventually lead to secondary acute myeloid leukemia, which has a …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … DESİTAB 50 MG IV ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMADA KULLANILACAK KONSANTRE İÇİN TOZ, 1 ADET ... DESİTU 50 MG İNFÜZYONLUK ÇÖZELTİ HAZIRLAMADA KULLANILACAK KONSANTRE İÇİN TOZ, 1 ADET ... DESİBEM 50 MG İNFÜZYONLUK ÇÖZELTİ HAZIRLAMADA KULLANILACAK KONSANTRE İÇİN TOZ, 1 ADET …
Gimeracil
Gimeracil is an adjunct to antineoplastic therapy, used to increase the concentration and effect of the main active componets within chemotherapy regimens. Approved by the European Medicines Agency (EMA) in March 2011, Gimeracil is available in combination with DB03209 and DB09256 within the commercially available product "Teysuno". The main active...
Approved
Matched Synonyms: … Ts-1 (TN) …
Matched Description: … The main active ingredient in Teysuno is [DB09256], a pro-drug of [DB00544] (5-FU), which is a cytotoxic ... By mimicking a class of compounds called "pyrimidines" that are essential components of RNA and DNA, ... This allows higher concentrations of 5-FU to be achieved with a lower dose of tegafur, thereby also reducing …
Matched Mixtures name: … TS ONE OD Tablet 20 ... TS-ONE Capsule 20 ... TS-ONE CAPSULE 20 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Description: … The main active ingredient in Teysuno is [DB09256], a pro-drug of [DB00544] (5-FU), which is a cytotoxic ... By mimicking a class of compounds called "pyrimidines" that are essential components of RNA and DNA, ... This allows higher concentrations of 5-FU to be achieved with a lower dose of tegafur, thereby also reducing …
Matched Mixtures name: … TS ONE OD Tablet 20 ... TS-ONE Capsule 20 ... TS-ONE CAPSULE 20 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Reteplase
Human tissue plasminogen activator, purified, glycosylated, 355 residues purified from CHO cells. Retavase is considered a "third-generation" thrombolytic agent, genetically engineered to retain and delete certain portions of human tPA. Retavase is a deletion mutein of human tPA formed by deleting various amino acids present in endogenous human tPA. Retavase...
Approved
Investigational
Matched Synonyms: … Human t-PA (residues 1-3 and 176-527) …
Matched Description: … Retavase is considered a "third-generation" thrombolytic agent, genetically engineered to retain and ... Three domains are deleted from retavase - kringle-1, finger, and epidermal growth factor (EGF). ... Retavase is a deletion mutein of human tPA formed by deleting various amino acids present in endogenous …
Matched Description: … Retavase is considered a "third-generation" thrombolytic agent, genetically engineered to retain and ... Three domains are deleted from retavase - kringle-1, finger, and epidermal growth factor (EGF). ... Retavase is a deletion mutein of human tPA formed by deleting various amino acids present in endogenous …
Tranylcypromine
A propylamine formed from the cyclization of the side chain of amphetamine. This monoamine oxidase inhibitor is effective in the treatment of major depression, dysthymic disorder, and atypical depression. It also is useful in panic and phobic disorders (From AMA Drug Evaluations Annual, 1994, p311).
Tranylcypromine is a racemate comprising...
Approved
Investigational
Matched Synonyms: … (1R*,2S*)-2-phenylcyclopropan-1-amine …
Matched Iupac: … 2-phenylcyclopropan-1-amine …
Matched Description: … Tranylcypromine is a racemate comprising equal amounts of (1R,2S)- and (1S,2R)-2-phenylcyclopropan-1- ... A propylamine formed from the cyclization of the side chain of amphetamine. …
Matched Categories: … Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates …
Matched Products: … Tranylcypromin Aristo 20 mg Filmtabletten …
Matched Iupac: … 2-phenylcyclopropan-1-amine …
Matched Description: … Tranylcypromine is a racemate comprising equal amounts of (1R,2S)- and (1S,2R)-2-phenylcyclopropan-1- ... A propylamine formed from the cyclization of the side chain of amphetamine. …
Matched Categories: … Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates …
Matched Products: … Tranylcypromin Aristo 20 mg Filmtabletten …
Gadopiclenol
Gadopiclenol is a gadolinium-based contrast agent (GBCA) based on a pyclen macrocyclic structure. It is indicated for use with magnetic resonance imaging (MRI) to detect and visualize lesions with abnormal vascularity in the central nervous system and the body. In 2006, the use of GBCAs was associated with the development...
Approved
Matched Synonyms: … -1(15),11,13-trien-6-yl]-5-(2,3-dihydroxypropylamino)-5-oxopentanoate;gadolinium(3+) ... ,.alpha.9-tris(3-((2,3-dihydroxypropyl)amino)-3-oxopropyl)-3,6,9,15-tetraazabicyclo(9.3.1)pentadeca-1( ... 2-[3,9-bis[1-carboxylato-4-(2,3-dihydroxypropylamino)-4-oxobutyl]-3,6,9,15-tetrazabicyclo[9.3.1]pentadeca …
Matched Iupac: … [9.3.1]pentadeca-1(14),11(15),12-trien-3-yl]-4-[(2,3-dihydroxypropyl)carbamoyl]butanoate ... gadolinium(3+) 2-[6,9-bis({1-carboxylato-3-[(2,3-dihydroxypropyl)carbamoyl]propyl})-3,6,9,15-tetraazabicyclo …
Matched Description: … Gadopiclenol is a gadolinium-based contrast agent (GBCA) based on a pyclen macrocyclic structure. ... 2006, the use of GBCAs was associated with the development of nephrogenic systemic fibrosis (NSF), a ... [A254002] Gadopiclenol has high kinetic stability and a high r1 relaxivity, allowing it to be used at …
Matched Iupac: … [9.3.1]pentadeca-1(14),11(15),12-trien-3-yl]-4-[(2,3-dihydroxypropyl)carbamoyl]butanoate ... gadolinium(3+) 2-[6,9-bis({1-carboxylato-3-[(2,3-dihydroxypropyl)carbamoyl]propyl})-3,6,9,15-tetraazabicyclo …
Matched Description: … Gadopiclenol is a gadolinium-based contrast agent (GBCA) based on a pyclen macrocyclic structure. ... 2006, the use of GBCAs was associated with the development of nephrogenic systemic fibrosis (NSF), a ... [A254002] Gadopiclenol has high kinetic stability and a high r1 relaxivity, allowing it to be used at …
Cefotetan
A semisynthetic cephamycin antibiotic that is administered intravenously or intramuscularly. The drug is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range of both aerobic and anaerobic gram-positive and gram-negative microorganisms.
Approved
Matched Synonyms: … -5- yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2- carboxylic acid ... (6R,7S)-7-(4-(carbamoylcarboxymethylene)-1,3-dithiethane-2-carboxamido)-7-methoxy-3-(((1-methyl-1H-tetrazol …
Matched Iupac: … -tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid ... (6R,7S)-7-{4-[carbamoyl(carboxy)methylidene]-1,3-dithietane-2-amido}-7-methoxy-3-{[(1-methyl-1H-1,2,3,4 …
Matched Description: … The drug is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range ... A semisynthetic cephamycin antibiotic that is administered intravenously or intramuscularly. …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … -tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid ... (6R,7S)-7-{4-[carbamoyl(carboxy)methylidene]-1,3-dithietane-2-amido}-7-methoxy-3-{[(1-methyl-1H-1,2,3,4 …
Matched Description: … The drug is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range ... A semisynthetic cephamycin antibiotic that is administered intravenously or intramuscularly. …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Alitretinoin
An important regulator of gene expression during growth and development, and in neoplasms. Tretinoin, also known as retinoic acid and derived from maternal vitamin A, is essential for normal growth; and embryonic development. An excess of tretinoin can be teratogenic. It is used in the treatment of psoriasis; acne vulgaris;...
Approved
Investigational
Matched Synonyms: … (2E,4E,6Z,8E)-3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid …
Matched Iupac: … (2E,4E,6Z,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid …
Matched Description: … Tretinoin, also known as retinoic acid and derived from maternal vitamin A, is essential for normal growth …
Matched Mixtures name: … Clindamycin 1% / Niacinamide 4% / Tretinoin 0.05% …
Matched Categories: … Vitamin A …
Matched Iupac: … (2E,4E,6Z,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid …
Matched Description: … Tretinoin, also known as retinoic acid and derived from maternal vitamin A, is essential for normal growth …
Matched Mixtures name: … Clindamycin 1% / Niacinamide 4% / Tretinoin 0.05% …
Matched Categories: … Vitamin A …
Simvastatin
Simvastatin, also known as the brand name product Zocor, is a lipid-lowering drug derived synthetically from a fermentation product of Aspergillus terreus. It belongs to the statin class of medications, which are used to lower the risk of cardiovascular disease and manage abnormal lipid levels by inhibiting the endogenous production...
Approved
Matched Synonyms: … dimethylbutyric acid, 8-ester with (4R,6R)-6-(2-((1S,2S,6R,8S,8aR)-1,2,6,7,8,8a-hexahydro-8-hydroxy-2,6-dimethyl-1- …
Matched Iupac: … 8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1- …
Matched Description: … event occurring within 5 years) statins cause a 20%-22% relative reduction in major cardiovascular events ... (heart attack, stroke, coronary revascularization, and coronary death) for every 1 mmol/L reduction ... from a fermentation product of _Aspergillus terreus_. …
Matched Mixtures name: … VYTORIN ® 10/20 MG ... EZIT - ST® 10/20 ... DUTEZENPLUS 10/20 …
Matched Products: … SIMVAS-20 TABLET 20 mg ... SIMVOR 20 TABLET 20 mg ... SIMTIN-20 TABLET 20 mg …
Matched Iupac: … 8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1- …
Matched Description: … event occurring within 5 years) statins cause a 20%-22% relative reduction in major cardiovascular events ... (heart attack, stroke, coronary revascularization, and coronary death) for every 1 mmol/L reduction ... from a fermentation product of _Aspergillus terreus_. …
Matched Mixtures name: … VYTORIN ® 10/20 MG ... EZIT - ST® 10/20 ... DUTEZENPLUS 10/20 …
Matched Products: … SIMVAS-20 TABLET 20 mg ... SIMVOR 20 TABLET 20 mg ... SIMTIN-20 TABLET 20 mg …
Displaying drugs 151 - 175 of 13294 in total