Displaying drugs 1751 - 1775 of 2820 in total
L-Threonohydroxamate 4-Phosphate
Experimental
Matched Name: … L-Threonohydroxamate 4-Phosphate …
Matched Iupac: … [(2S,3R,4S)-2,3,4-trihydroxy-4-(hydroxyamino)butoxy]phosphonic acid …
Matched Iupac: … [(2S,3R,4S)-2,3,4-trihydroxy-4-(hydroxyamino)butoxy]phosphonic acid …
5-FLUOROINDOLE PROPANOL PHOSPHATE
Experimental
Matched Name: … 5-FLUOROINDOLE PROPANOL PHOSPHATE …
Matched Iupac: … [3-(5-fluoro-1H-indol-3-yl)propoxy]phosphonic acid …
Matched Iupac: … [3-(5-fluoro-1H-indol-3-yl)propoxy]phosphonic acid …
Quercetin-3'-O-phosphate
Quercetin-3'-O-phosphate has been used in trials studying the treatment of Insulin Resistance and Impaired Glucose Tolerance.
Investigational
Matched Name: … Quercetin-3'-O-phosphate …
Matched Iupac: … [2-hydroxy-5-(3,5,7-trihydroxy-4-oxo-4H-chromen-2-yl)phenoxy]phosphonic acid …
Matched Description: … Quercetin-3'-O-phosphate has been used in trials studying the treatment of Insulin Resistance and Impaired …
Matched Iupac: … [2-hydroxy-5-(3,5,7-trihydroxy-4-oxo-4H-chromen-2-yl)phenoxy]phosphonic acid …
Matched Description: … Quercetin-3'-O-phosphate has been used in trials studying the treatment of Insulin Resistance and Impaired …
Glyceraldehyde-3-Phosphate Dehydrogenase
Investigational
Matched Name: … Glyceraldehyde-3-Phosphate Dehydrogenase …
Matched Categories: … Enzymes and Coenzymes ... Glyceraldehyde-3-Phosphate Dehydrogenases, antagonists & inhibitors …
Matched Categories: … Enzymes and Coenzymes ... Glyceraldehyde-3-Phosphate Dehydrogenases, antagonists & inhibitors …
Norleucine Phosphonate
Experimental
Matched Name: … Norleucine Phosphonate …
Matched Iupac: … [(1R)-1-aminopentyl]phosphonic acid …
Matched Iupac: … [(1R)-1-aminopentyl]phosphonic acid …
Methionine Phosphonate
Experimental
Matched Name: … Methionine Phosphonate …
Matched Iupac: … [(1R)-1-amino-3-(methylsulfanyl)propyl]phosphonic acid …
Matched Iupac: … [(1R)-1-amino-3-(methylsulfanyl)propyl]phosphonic acid …
Alkaline Phosphatase
Alkaline Phosphatase (AP) is an oral treatment and has a very
favorable side-effect profile. AP only acts locally in the colon to reduce the continuous inflammation of the colon by endotoxin from Gram-negative bacteria and extracellular ATP in UC patients.
Investigational
Matched Name: … Alkaline Phosphatase …
Matched Description: … Alkaline Phosphatase (AP) is an oral treatment and has a very favorable side-effect profile. ... the colon to reduce the continuous inflammation of the colon by endotoxin from Gram-negative bacteria and …
Matched Categories: … Enzymes and Coenzymes …
Matched Description: … Alkaline Phosphatase (AP) is an oral treatment and has a very favorable side-effect profile. ... the colon to reduce the continuous inflammation of the colon by endotoxin from Gram-negative bacteria and …
Matched Categories: … Enzymes and Coenzymes …
Pentobarbital
A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally. It is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration. (From AMA...
Approved
Investigational
Vet approved
Matched Synonyms: … 5-ethyl-5-(sec-pentyl)barbituric acid ... 5-ethyl-5-(1-methylbutyl)barbituric acid …
Matched Description: … agent and is usually given orally. ... A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) …
Matched Categories: … Hypnotics and Sedatives …
Matched Description: … agent and is usually given orally. ... A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) …
Matched Categories: … Hypnotics and Sedatives …
Artesunate
Artesunate is indicated for the initial treatment of severe malaria. The World Health Organization recommends artesunate as first line treatment for severe malaria. Artesunate was developed out of a need for a more hydrophilic derivative of artemisinin. Artesunate was granted FDA approval on 26 May 2020.
Approved
Investigational
Matched Synonyms: … Artesunic acid ... butanedioic acid, 1-[(3R,5aS,6R,8aS,9R,10S,12R,12aR)-decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[ …
Matched Iupac: … 13R)-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.0⁴,¹³.0⁸,¹³]hexadecan-10-yl]oxy}butanoic acid …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... Dicarboxylic Acids ... Artemisinin and derivatives ... Antiparasitic Products, Insecticides and Repellents …
Matched Iupac: … 13R)-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.0⁴,¹³.0⁸,¹³]hexadecan-10-yl]oxy}butanoic acid …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... Dicarboxylic Acids ... Artemisinin and derivatives ... Antiparasitic Products, Insecticides and Repellents …
Oxybuprocaine
Oxybuprocaine (also known as Benoxinate) is a local anesthetic, which is used especially in ophthalmology and otolaryngology. Oxybuprocaine binds to sodium channels and reversibly stabilizes the neuronal membrane which decreases its permeability to sodium ions.
Approved
Investigational
Matched Synonyms: … 4-Amino-3-butoxy-2-(diethylamino)ethyl ester benzoic acid ... 4-Amino-3-butoxy-benzoic acid 2-diethylamino-ethyl ester …
Matched Description: … Oxybuprocaine (also known as Benoxinate) is a local anesthetic, which is used especially in ophthalmology and ... Oxybuprocaine binds to sodium channels and reversibly stabilizes the neuronal membrane which decreases …
Matched Mixtures name: … Fluorescein Sodium and Benoxinate Hydrochloride ... Fluorescein Sodium and Benoxinate Hydrochloride ... Fluorescein Sodium and Benoxinate Hydrochloride …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids …
Matched Description: … Oxybuprocaine (also known as Benoxinate) is a local anesthetic, which is used especially in ophthalmology and ... Oxybuprocaine binds to sodium channels and reversibly stabilizes the neuronal membrane which decreases …
Matched Mixtures name: … Fluorescein Sodium and Benoxinate Hydrochloride ... Fluorescein Sodium and Benoxinate Hydrochloride ... Fluorescein Sodium and Benoxinate Hydrochloride …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids …
Nevirapine
A potent, non-nucleoside reverse transcriptase inhibitor (NNRTI) used in combination with nucleoside analogues for treatment of Human Immunodeficiency Virus Type 1 (HIV-1) infection and AIDS. Structurally, nevirapine belongs to the dipyridodiazepinone chemical class.
Approved
Matched Synonyms: … Nevirapine anhydrous ... Nevirapine, anhydrous …
Matched Description: … combination with nucleoside analogues for treatment of Human Immunodeficiency Virus Type 1 (HIV-1) infection and …
Matched Mixtures name: … Lamivudine, Nevirapine, and Zidovudine ... LAMIVUDINE, NEVIRAPINE AND ZIDOVUDINE TABLETS (150/200/300 mg) …
Matched Categories: … Nucleic Acid Synthesis Inhibitors ... stavudine, lamivudine and nevirapine ... zidovudine, lamivudine and nevirapine ... Metabolic Side Effects of Drugs and Substances …
Matched Description: … combination with nucleoside analogues for treatment of Human Immunodeficiency Virus Type 1 (HIV-1) infection and …
Matched Mixtures name: … Lamivudine, Nevirapine, and Zidovudine ... LAMIVUDINE, NEVIRAPINE AND ZIDOVUDINE TABLETS (150/200/300 mg) …
Matched Categories: … Nucleic Acid Synthesis Inhibitors ... stavudine, lamivudine and nevirapine ... zidovudine, lamivudine and nevirapine ... Metabolic Side Effects of Drugs and Substances …
fb-PMT
Investigational
Matched Synonyms: … )-polyethyleneglycol36))-1H-1,2,3-triazol-4-yl)methoxy)-3,5- diiodophenoxy)-3,5-diiodophenyl)acetic acid ... O,O'-Bis({4-[3,5-diiodo-4-(1-methylene-1,2,3-triazol-4-ylmethoxy)phenoxy]-3,5-diiodophenyl}acetic acid ... O,O′-Bis({4-[3,5-diiodo-4-(1-methylen-1,2,3-triazol-4-ylmethoxy)phenoxy]-3,5-diiodophenyl}acetic acid …
Enoxacin
A broad-spectrum 6-fluoronaphthyridinone antibacterial agent (fluoroquinolones) structurally related to nalidixic acid.
Approved
Investigational
Matched Synonyms: … 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-1,8-naphthyridine-3-carboxylic acid ... 1-Ethyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid …
Matched Iupac: … 1-ethyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid …
Matched Description: … broad-spectrum 6-fluoronaphthyridinone antibacterial agent (fluoroquinolones) structurally related to nalidixic acid …
Matched Categories: … Metabolic Side Effects of Drugs and Substances …
Matched Iupac: … 1-ethyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid …
Matched Description: … broad-spectrum 6-fluoronaphthyridinone antibacterial agent (fluoroquinolones) structurally related to nalidixic acid …
Matched Categories: … Metabolic Side Effects of Drugs and Substances …
Elafibranor
Elafibranor is a dual peroxisome proliferator-activated receptor (PPAR) α and β/δ agonist. On June 10, 2024, elafibranor was granted accelerated approval by the FDA for the treatment of primary biliary cholangitis (PBC).
Approved
Investigational
Matched Synonyms: … PROPANOIC ACID, 2-(2,6-DIMETHYL-4-((1E)-3-(4-(METHYLTHIO)PHENYL)-3-OXO-1-PROPEN-1-YL)PHENOXY)- ... PROPANOIC ACID, 2-(2,6-DIMETHYL-4-(3-(4-(METHYLTHIO)PHENYL)-3-OXO-1-PROPEN-1-YL)PHENOXY)-2-METHYL- …
Matched Iupac: … 2-{2,6-dimethyl-4-[(1E)-3-[4-(methylsulfanyl)phenyl]-3-oxoprop-1-en-1-yl]phenoxy}-2-methylpropanoic acid …
Matched Description: … Elafibranor is a dual peroxisome proliferator-activated receptor (PPAR) α and β/δ agonist. …
Matched Categories: … Alimentary Tract and Metabolism ... Bile and Liver Therapy ... Acids, Acyclic ... Carboxylic Acids …
Matched Iupac: … 2-{2,6-dimethyl-4-[(1E)-3-[4-(methylsulfanyl)phenyl]-3-oxoprop-1-en-1-yl]phenoxy}-2-methylpropanoic acid …
Matched Description: … Elafibranor is a dual peroxisome proliferator-activated receptor (PPAR) α and β/δ agonist. …
Matched Categories: … Alimentary Tract and Metabolism ... Bile and Liver Therapy ... Acids, Acyclic ... Carboxylic Acids …
Pralatrexate
Pralatrexate is an antifolate for the treatment of relapsed or refractory peripheral T-cell lymphoma . Pralatrexate was developed in response due to the inferior responses of patients using the standard therapy for their B-cells counterparts. Compared to methotrexate, pralatrexate has better accumulation in cancer cells. Pralatrexate is designed to have...
Approved
Investigational
Matched Synonyms: … N-(4-(1-((2,4-Diamino-6-pteridinyl)methyl)-3-butynyl)benzoyl)-L-glutamic acid ... (2S)-2-({4-[1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl]benzoyl}amino)pentanedioic acid ... (2S)-2-((4-((1RS)-1-((2,4-Diaminopteridin-6-yl)methyl)but-3-ynyl)benzoyl)amino)pentanedioic acid …
Matched Iupac: … (2S)-2-({4-[1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl]phenyl}formamido)pentanedioic acid …
Matched Description: … lung cancer, breast cancer, and bladder cancer. ... higher affinity for the reduced folate carrier, a protein that is overexpressed in malignant cells and ... [L37674] It is also being studied for other types of lymphoma and solid malignancy such as non-small-cell …
Matched Categories: … Folic Acid Analogues ... Folic Acid Antagonists ... Antineoplastic and Immunomodulating Agents …
Matched Iupac: … (2S)-2-({4-[1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl]phenyl}formamido)pentanedioic acid …
Matched Description: … lung cancer, breast cancer, and bladder cancer. ... higher affinity for the reduced folate carrier, a protein that is overexpressed in malignant cells and ... [L37674] It is also being studied for other types of lymphoma and solid malignancy such as non-small-cell …
Matched Categories: … Folic Acid Analogues ... Folic Acid Antagonists ... Antineoplastic and Immunomodulating Agents …
Levocetirizine
Levocetirizine is a selective histamine H1 antagonist used to treat a variety of allergic symptoms.[A181748,A181790,L7694] It is the R enantiomer of cetirizine. Levocetirizine has greater affinity for the histamine H1 receptor than cetirizine. Levocetirizine was granted FDA approval in 1995.
Approved
Matched Synonyms: … 2-(2-{4-[(R)-(4-chlorophenyl)(phenyl)methyl]piperazin-1-yl}ethoxy)acetic acid …
Matched Iupac: … 2-(2-{4-[(R)-(4-chlorophenyl)(phenyl)methyl]piperazin-1-yl}ethoxy)acetic acid …
Matched Categories: … Cetirizine and isomer …
Matched Iupac: … 2-(2-{4-[(R)-(4-chlorophenyl)(phenyl)methyl]piperazin-1-yl}ethoxy)acetic acid …
Matched Categories: … Cetirizine and isomer …
Mebenil
An obsolete fungicide used to control various pathogens on cereals and seed potatoes.
Experimental
Matched Synonyms: … 2-Methylbenzoic acid anilide …
Matched Description: … An obsolete fungicide used to control various pathogens on cereals and seed potatoes. …
Matched Description: … An obsolete fungicide used to control various pathogens on cereals and seed potatoes. …
Tigulixostat
Investigational
Matched Synonyms: … 1h-pyrazole-4-carboxylic acid, 1-(3-cyano-1-(1-methylethyl)-1h-indol-5-yl)- …
D-pantetheine 4'-phosphate
Experimental
Matched Synonyms: … Pantetheine-4'-phosphate …
Matched Name: … D-pantetheine 4'-phosphate …
Matched Iupac: … [(3R)-3-hydroxy-2,2-dimethyl-3-({2-[(2-sulfanylethyl)carbamoyl]ethyl}carbamoyl)propoxy]phosphonic acid …
Matched Name: … D-pantetheine 4'-phosphate …
Matched Iupac: … [(3R)-3-hydroxy-2,2-dimethyl-3-({2-[(2-sulfanylethyl)carbamoyl]ethyl}carbamoyl)propoxy]phosphonic acid …
Masoprocol
A potent lipoxygenase inhibitor that interferes with arachidonic acid metabolism. The compound also inhibits formyltetrahydrofolate synthetase, carboxylesterase, and cyclooxygenase to a lesser extent. It also serves as an antioxidant in fats and oils. [PubChem]
Approved
Investigational
Matched Synonyms: … erythro-nordihydroguaiaretic acid ... Nordihydroguaiaretic acid ... meso-nordihydroguaiaretic acid …
Matched Description: … It also serves as an antioxidant in fats and oils. [PubChem] ... A potent lipoxygenase inhibitor that interferes with arachidonic acid metabolism. ... The compound also inhibits formyltetrahydrofolate synthetase, carboxylesterase, and cyclooxygenase to …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Description: … It also serves as an antioxidant in fats and oils. [PubChem] ... A potent lipoxygenase inhibitor that interferes with arachidonic acid metabolism. ... The compound also inhibits formyltetrahydrofolate synthetase, carboxylesterase, and cyclooxygenase to …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Sinefungin
Sinefungin is a solid. This compound belongs to the purine nucleosides and analogues. These are compounds comprising a purine base attached to a sugar. The proteins that adenosyl-ornithine target include RdmB, modification methylase TaqI, rRNA (adenine-N6-)-methyltransferase, and modification methylase RsrI.
Experimental
Matched Synonyms: … 6,9-Diamino-1-(6-amino-9H-purin-9-yl)-1,5,6,7,8,9-hexadeoxydecofuranuronic acid ... 6,9-Diamino-1-(6-amino-9H-purin-9-yl)-1,5,6,7,8,9-hexadeoxy-beta-D-ribo-decofuranuronic acid ... 5S)-2,5-diamino-6-[(2R,3S,R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]hexanoic acid …
Matched Iupac: … (2S,5S)-2,5-diamino-6-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]hexanoic acid …
Matched Description: … This compound belongs to the purine nucleosides and analogues. ... adenosyl-ornithine target include RdmB, modification methylase TaqI, rRNA (adenine-N6-)-methyltransferase, and …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Iupac: … (2S,5S)-2,5-diamino-6-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]hexanoic acid …
Matched Description: … This compound belongs to the purine nucleosides and analogues. ... adenosyl-ornithine target include RdmB, modification methylase TaqI, rRNA (adenine-N6-)-methyltransferase, and …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Bexotegrast
Investigational
Matched Synonyms: … METHOXYETHYL-(4-(5,6,7,8-TETRAHYDRO-1,8-NAPHTHYRIDIN-2-YL)BUTYL)AMINO)-2-(QUINAZOLIN-4-YLAMINO)BUTANOIC ACID ... Methoxyethyl)[4-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)butyl]amino]-2-[(quinazolin-4-yl)amino]butanoic acid ... Butanoic acid, 4-[(2-methoxyethyl)[4-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)butyl]amino]-2-(4-quinazolinylamino …
Matched Iupac: … methoxyethyl)[4-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)butyl]amino]-2-[(quinazolin-4-yl)amino]butanoic acid …
Matched Iupac: … methoxyethyl)[4-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)butyl]amino]-2-[(quinazolin-4-yl)amino]butanoic acid …
Capecitabine
Capecitabine is an orally-administered chemotherapeutic agent used in the treatment of metastatic breast and colorectal cancers. Capecitabine is a prodrug, that is enzymatically converted to fluorouracil (antimetabolite) in the tumor, where it inhibits DNA synthesis and slows growth of tumor tissue.
Approved
Investigational
Matched Synonyms: … (1-(5-Deoxy-beta-D-ribofuranosyl)-5-fluoro-1,2-dihydro-2-oxo-4-pyrimidinyl)-carbamic acid pentyl ester ... Pentyl [1-(5-deoxy-β-D-ribofuranosyl)-5-fluoro-2-oxo-1,2-dihydropyrimidin-4-yl]carbamate …
Matched Iupac: … pentyl N-{1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-methyloxolan-2-yl]-5-fluoro-2-oxo-1,2-dihydropyrimidin-4-yl}carbamate …
Matched Description: … Capecitabine is an orally-administered chemotherapeutic agent used in the treatment of metastatic breast and ... enzymatically converted to fluorouracil (antimetabolite) in the tumor, where it inhibits DNA synthesis and …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... Antineoplastic and Immunomodulating Agents ... Fluorouracil and prodrugs ... Nucleic Acid Synthesis Inhibitors …
Matched Iupac: … pentyl N-{1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-methyloxolan-2-yl]-5-fluoro-2-oxo-1,2-dihydropyrimidin-4-yl}carbamate …
Matched Description: … Capecitabine is an orally-administered chemotherapeutic agent used in the treatment of metastatic breast and ... enzymatically converted to fluorouracil (antimetabolite) in the tumor, where it inhibits DNA synthesis and …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... Antineoplastic and Immunomodulating Agents ... Fluorouracil and prodrugs ... Nucleic Acid Synthesis Inhibitors …
4-Nitrophenyl (3S)-3-({N-[(benzyloxy)carbonyl]-L-phenylalanyl}amino)-5-phenyl-1-pentanesulfonate
Experimental
Matched Synonyms: … 3-[N-[Benzyloxycarbonyl]-phenylalaninyl-amino]-5-phenyl-pentane-1-sulfonic acid 4-nitro-phenyl ester …
Matched Iupac: … benzyl N-[(1S)-1-{[(3S)-1-[(4-nitrophenoxy)sulfonyl]-5-phenylpentan-3-yl]carbamoyl}-2-phenylethyl]carbamate …
Matched Iupac: … benzyl N-[(1S)-1-{[(3S)-1-[(4-nitrophenoxy)sulfonyl]-5-phenylpentan-3-yl]carbamoyl}-2-phenylethyl]carbamate …
BMS-181156
Experimental
Matched Synonyms: … (E)-4-(3-Oxo-3-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid …
Matched Iupac: … 4-[(1E)-3-oxo-3-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)prop-1-en-1-yl]benzoic acid …
Matched Iupac: … 4-[(1E)-3-oxo-3-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)prop-1-en-1-yl]benzoic acid …
Displaying drugs 1751 - 1775 of 2820 in total