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Displaying drugs 1751 - 1775 of 1997 in total

Fremanezumab

Fremanezumab is a humanized monoclonal antibody targeted against human calcitonin gene-related peptide (CGRP) for the prevention of migraine headaches. It was developed by Teva Pharmaceuticals USA and approved by the FDA in September 2018. Along with other recently approved anti-CGRP therapies such as galcanezumab, erenumab, and the oral CGRP antagonist...
Approved
Investigational
Matched Description: … [L11749] It was developed by Teva Pharmaceuticals USA and approved by the FDA in September 2018. ... [L11779] Along with other recently approved anti-CGRP therapies such as [galcanezumab], [erenumab], and ... oral CGRP antagonist [ubrogepant], fremanezumab represents an important step forward in the treatment and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … AJOVY SOLUTION FOR INJECTION IN PRE-FILLED PEN 225 MG/1.5ML ... AJOVY SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 225 MG/1.5ML …

Calcium Phosphate

Calcium phosphate is typically available as an over the counter supplement, antacid, or as an added ingredient in some toothpastes [FDA Label] .
Approved
Matched Mixtures name: … Multivitamins and Minerals for Men ... Multivitamins and Minerals for Women ... Multivitamins and Minerals for Young Men …
Matched Categories: … Alimentary Tract and Metabolism ... ascorbic acid (vit C) and calcium …
Matched Products: … CAREDO Repairing Dental Caries for Kids Toothpastes 50g …

Methylprednisolone hemisuccinate

A water-soluble ester of methylprednisolone used for cardiac, allergic, and hypoxic emergencies.
Approved
Matched Description: … A water-soluble ester of methylprednisolone used for cardiac, allergic, and hypoxic emergencies. …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … MEDASON FOR INJECTION ... Medixon Powder for Injection 500 mg ... SOLU-MEDROL FOR INJECTION 500 mg/8 ml …

Cloprostenol

Vet approved
Matched Categories: … Hormonal Contraceptives for Systemic Use ... Prostaglandins, Synthetic ... Prostaglandins F, Synthetic …
Matched Products: … GESTAVET PROST (d-cloprostenol 75 mcg/ml solution for injection) …

Dexrazoxane

An antimitotic agent with immunosuppressive properties. Dexrazoxane, the (+)-enantiomorph of razoxane, provides cardioprotection against anthracycline toxicity. It appears to inhibit formation of a toxic iron-anthracycline complex. [PubChem] The Food and Drug Administration has designated dexrazoxane as an orphan drug for use in the prevention or reduction in the incidence and...
Approved
Withdrawn
Matched Description: … [PubChem] The Food and Drug Administration has designated dexrazoxane as an orphan drug for use in the ... prevention or reduction in the incidence and severity of anthracycline-induced cardiomyopathy. …
Matched Categories: … Detoxifying Agents for Antineoplastic Treatment …
Matched Products: … Dexrazoxane for Injection …

Vigabatrin

Vigabatrin is an analog of gamma-aminobutyric acid (GABA), the main inhibitory neurotransmitter in the central nervous system, used in the treatment of refractory seizures and infantile spasms. It irreversibly inhibits the enzyme responsible for GABA metabolism, thereby increasing levels of circulating GABA. Although administered as a racemic mixture, only the...
Approved
Matched Description: … [A202124] Its use is now generally reserved for patients who have failed alternative therapies, and its ... inhibitory neurotransmitter in the central nervous system, used in the treatment of refractory seizures and ... [A202037] It was first introduced as an antiepileptic agent in the United Kingdom in 1989 and was …
Matched Products: … Vigabatrin for Oral Solution ... Vigabatrin for oral solution USP, 500 mg …

Olodaterol

Olodaterol is a novel, long-acting beta2-adrenergic agonist (LABA) that exerts its pharmacological effect by binding and activating beta2-adrenergic receptors located primarily in the lungs. Beta2-adrenergic receptors are membrane-bound receptors that are normally activated by endogenous epinephrine whose signalling, via a downstream L-type calcium channel interaction, mediates smooth muscle relaxation and...
Approved
Matched Description: … novel, long-acting beta2-adrenergic agonist (LABA) that exerts its pharmacological effect by binding and ... LABAs including improved convenience and compliance and improved airflow over a 24-hour period. ... (COPD) and the progressive airflow obstruction that is characteristic of it. …
Matched Categories: … olodaterol and tiotropium bromide ... Drugs for Obstructive Airway Diseases …
Matched Products: … Striverdi Respimat Solution for Inhalation 2.5 microgram/ actuation ... SPIOLTO® RESPIMAT® RE-USABLE SOLUTION FOR INHALATION 2.5 MICROGRAM / 2.5 MICROGRAM …

Cabotegravir

Cabotegravir, or GSK1265744, is an HIV-1 integrase inhibitor that is prescribed with the non-nucleoside reverse transcriptase inhibitor, rilpivirine.[A227668,L31188,L31193] Early research into cabotegravir showed it had lower oral bioavailability than dolutegravir, which resulted in the development of long acting monthly intramuscular injection formulation for cabotegravir.[A227668,L31193] Cabotegravir was granted FDA approval on...
Approved
Investigational
Matched Description: … dosing every two months on February 01, 2022 [L40084] and without the need for an oral lead-in period ... A227668] which resulted in the development of long acting monthly intramuscular injection formulation for ... While previously administered once monthly only, this combination product was granted FDA approval for …
Matched Categories: … Antivirals for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … Apretude 600mg Prolonged-release suspension for injection …

Influenza A virus A/Vietnam/1194/2004 (H5N1) antigen (formaldehyde inactivated)

Approved
Matched Products: … Pandemic Influenza Vaccine H5N1 Baxter Suspension for Injection …

Dantrolene

Chemically, dantrolene is a hydantoin derivative, but does not exhibit antiepileptic activity like other hydantoin derivates such as phenytoin.
Approved
Investigational
Matched Categories: … Dantrolene and Derivatives …
Matched Products: … Dantrolene Sodium for Injection, USP …

Lutropin alfa

Lutropin alfa is a recombinant human luteinizing hormone produced in yeast with 2 subunits, alpha = 92 residues, beta = 121 residues. It is a heterodimeric glycoprotein made up of monomeric units. Lutropin alfa was the first and only recombinant human form of luteinizing hormone (LH) developed for use in...
Approved
Matched Description: … Lutropin alfa was the first and only recombinant human form of luteinizing hormone (LH) developed for ... biological activity of endogenous LH; an acute rise of LH, or LH surge, in females triggers ovulation and …
Matched Mixtures name: … Pergoveris 150IU/75IU powder and solvent for solution for injection ... Pergoveris Powder and Solvent for Solution for Injection 150iu/75iu …
Matched Categories: … Genito Urinary System and Sex Hormones ... Gonadotropins and Antigonadotropins ... Sex Hormones and Modulators of the Genital System …
Matched Products: … LUVERIS FOR INJECTION 75 iu/vial (Revised formula) …

Ioflupane I-123

Ioflupane (I-123) is a radiopharmaceutical used to image dopamine neurons and diagnose Parkinsonian syndromes.
Approved
Matched Description: … Ioflupane (I-123) is a radiopharmaceutical used to image dopamine neurons and diagnose Parkinsonian syndromes …
Matched Products: … DATSCAN SOLUTION FOR INJECTION 74 MBQ/ML …

Epirubicin

An anthracycline which is the 4'-epi-isomer of doxorubicin. The compound exerts its antitumor effects by interference with the synthesis and function of DNA.
Approved
Matched Description: … The compound exerts its antitumor effects by interference with the synthesis and function of DNA. …
Matched Categories: … Anthracyclines and Related Substances ... Antineoplastic and Immunomodulating Agents ... Cytotoxic Antibiotics and Related Substances …
Matched Products: … EPIROL Epirubicin Hydrochloride Powder for Solution for Injection 10mg ... EPIROL Epirubicin Hydrochloride Powder for Solution for Injection 50mg ... Epirubicin for Injection …

Rabies virus inactivated antigen, A

Rabies virus inactivated antigen, A is an inactivated virus vacine for the intramuscular injection. It is an active immunization against rabies that can be administered pre- or post-exposure to the rabies virus.
Approved
Investigational
Matched Description: … Rabies virus inactivated antigen, A is an inactivated virus vacine for the intramuscular injection. …
Matched Categories: … Immune Sera and Immunoglobulins ... Antiinfectives for Systemic Use …
Matched Products: … Rabipur Lyophilised Powder for Injection …

Temsirolimus

Temsirolimus is a derivative of sirolimus used in the treatment of renal cell carcinoma (RCC). It was developed by Wyeth Pharmaceuticals under the trade name Torisel. Temsirolimus was approved by the FDA in late May 2007 as well as the European Medicines Agency (EMEA) on November 2007.
Approved
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Sirolimus and Prodrugs …
Matched Products: … Torisel Concentrate for Injection 25mg/mL …

Fosfomycin

Fosfomycin was discovered in 1969 by scientists at the Spanish Penicillin and Antibiotics Company and is produced by Streptomyces fradiae.[A229338,A230348] It may also be produced synthetically and is commercially available as the disodium salt for intravenous administration and as the calcium or trometamol salt for oral administration. In terms of...
Approved
Matched Description: … salt for intravenous administration and as the calcium or trometamol salt for oral administration. ... Fosfomycin was discovered in 1969 by scientists at the Spanish Penicillin and Antibiotics Company and ... group and an epoxide ring. …
Matched Categories: … Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … FOSMICIN FOR I.V. USE ... Fosfomycin Powder for Oral Solution ... URODAY 3g Granules for Oral Solution …

Alrizomadlin

Alrizomadlin is a novel MDM2 inhibitor that blocks the interaction of MDM2 and p53. It is being investigated in cancers.[A257281,A257286]
Investigational
Matched Synonyms: … (3'r,4's,5'r)-4-((6-chloro-2-oxo-1,2-dihydro-spiro(indole-3,3'-pyrrolidin)e-4'-(3-chloro-2-fluoro -phenyl …
Matched Description: … Alrizomadlin is a novel MDM2 inhibitor that blocks the interaction of MDM2 and p53. …

Indacaterol

Indacaterol is a novel, ultra-long-acting, rapid onset β(2)-adrenoceptor agonist developed for Novartis for the once-daily management of asthma and chronic obstructive pulmonary disease. It was approved by the European Medicines Agency (EMA) on 30 November 2009 and by the FDA on 1 July 2011. It is marketed in Europe as...
Approved
Matched Description: … for the once-daily management of asthma and chronic obstructive pulmonary disease. ... It is marketed in Europe as Onbrez and in America as Arcapta Neohaler. ... It was approved by the European Medicines Agency (EMA) on 30 November 2009 and by the FDA on 1 July 2011 …
Matched Categories: … indacaterol and mometasone ... indacaterol and glycopyrronium bromide ... indacaterol, glycopyrronium bromide and mometasone ... Drugs for Obstructive Airway Diseases …
Matched Products: … Onbrez Breezhaler Powder for inhalation Hard Capsule 300 mcg ... Onbrez Breezhaler Powder for Inhalation Hard Capsule 150 mcg …

N-(4-{[(3S)-3-(dimethylamino)pyrrolidin-1-yl]carbonyl}phenyl)-5-fluoro-4-[2-methyl-1-(1-methylethyl)-1H-imidazol-5-yl]pyrimidin-2-amine

Experimental
Matched Name: … N-(4-{[(3S)-3-(dimethylamino)pyrrolidin-1-yl]carbonyl}phenyl)-5-fluoro-4-[2-methyl-1-(1-methylethyl)- …
Matched Iupac: … N-{4-[(3S)-3-(dimethylamino)pyrrolidine-1-carbonyl]phenyl}-5-fluoro-4-[2-methyl-1-(propan-2-yl)-1H-imidazol …

6-(4-{(1S,2S)-2-AMINO-1-[(DIMETHYLAMINO)CARBONYL]-3-[(3S)-3-FLUOROPYRROLIDIN-1-YL]-3-OXOPROPYL}PHENYL)-1H-[1,2,4]TRIAZOLO[1,5-A]PYRIDIN-4-IUM

Experimental
Matched Name: … 6-(4-{(1S,2S)-2-AMINO-1-[(DIMETHYLAMINO)CARBONYL]-3-[(3S)-3-FLUOROPYRROLIDIN-1-YL]-3-OXOPROPYL}PHENYL …
Matched Iupac: … -amino-4-[(3S)-3-fluoropyrrolidin-1-yl]-N,N-dimethyl-4-oxo-2-(4-{[1,2,4]triazolo[1,5-a]pyridin-6-yl}phenyl …

Lenograstim

Lenograstim is a recombinant granulocyte colony-stimulating factor used as an immunostimulating agent.
Approved
Investigational
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins …
Matched Products: … GRANOCYTE 34 FOR INJECTION 263 mcg/ml …

2-(4-(2-((3-(5-(PYRIDIN-2-YLTHIO)THIAZOL-2-YL)UREIDO)METHYL)-1H-IMIDAZOL-4-YL)PHENOXY)ACETIC ACID

Experimental
Matched Name: … 2-(4-(2-((3-(5-(PYRIDIN-2-YLTHIO)THIAZOL-2-YL)UREIDO)METHYL)-1H-IMIDAZOL-4-YL)PHENOXY)ACETIC ACID …
Matched Iupac: … 2-(4-{2-[({[5-(pyridin-2-ylsulfanyl)-1,3-thiazol-2-yl]carbamoyl}amino)methyl]-1H-imidazol-4-yl}phenoxy …

Benzoic acid

A fungistatic compound that is widely used as a food preservative. It is conjugated to GLYCINE in the liver and excreted as hippuric acid. As the sodium salt form, sodium benzoate is used as a treatment for urea cycle disorders due to its ability to bind amino acids. This leads...
Approved
Investigational
Matched Description: … It is conjugated to GLYCINE in the liver and excreted as hippuric acid. ... This leads to excretion of these amino acids and a decrease in ammonia levels. ... Total Positive and Negative Syndrome Scale scores dropped by 21% compared to placebo. …
Matched Mixtures name: … REXOM WINACOL SYRUP FOR CHILDREN ... WOODS PEPPERMINT COUGH SYRUP FOR CHILDREN ... Sodium Phenylacetate and Sodium Benzoate …
Matched Categories: … Tests for Gastric Secretion ... Alimentary Tract and Metabolism ... Diet, Food, and Nutrition ... caffeine and sodium benzoate ... sodium benzoate and sodium phenylacetate …
Matched Products: … S Panax Mist for Refill …

Calfactant

Calfactant is a sterile, non-pyrogenic lung surfactant intended for intratracheal instillation. It is an off-white suspension of an extract of natural surfactant from calf lungs suspended in 0.9% saline. Each milliliter of calfactant contains 35mg of phospholipids (including 26 mg phosphatidylcholine of which 16 mg is disaturated phosphatidylcholine) and 0.65mg...
Approved
Matched Description: … 0.65mg of proteins including surfactant-associated proteins B and C. ... phospholipids (including 26 mg phosphatidylcholine of which 16 mg is disaturated phosphatidylcholine) and ... decrease the incidence of respiratory distress syndrome, mortality due to respiratory distress syndrome, and …
Matched Products: … BLES (bovine lipid extract surfactant) 27 mg/ml Suspension for Intratracheal Instillation …

Oseltamivir

Oseltamivir (marketed as the product TamifluⓇ), is an antiviral neuraminidase inhibitor used for the treatment and prophylaxis of infection with influenza viruses A (including pandemic H1N1) and B. Oseltamivir exerts its antiviral activity by inhibiting the activity of the viral neuraminidase enzyme found on the surface of the virus, which...
Approved
Matched Description: … treatment and prophylaxis of infection with influenza viruses A (including pandemic H1N1) and B. ... that early antiviral treatment can shorten the duration of fever and illness symptoms, and may reduce ... enzyme found on the surface of the virus, which prevents budding from the host cell, viral replication, and …
Matched Categories: … Antivirals for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … Oseltamivir Phosphate for Oral Suspension ... FLUHALT FOR ORAL SUSPENSION 60 mg/ 5 ml ... Oseltamivir Powder for Oral Suspension …
Displaying drugs 1751 - 1775 of 1997 in total