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Displaying drugs 1776 - 1800 of 1990 in total

XmAb 2513

XmAb 2513 is a humanized monoclonal antibody that targets the antigen CD30, a molecule expressed on the surface of a number of tumor cell types. It has been investigated for the treatment of hodgkin’s lymphoma.
Investigational
Matched Categories: … Amino Acids, Peptides, and Proteins …

Emricasan

Emricasan is the first caspase inhibitor tested in human which has received orphan drug status by FDA. It is developed by Pfizer and made in such a way that it protects liver cells from excessive apoptosis.
Investigational
Matched Description: … Emricasan is the first caspase inhibitor tested in human which has received orphan drug status by FDA ... It is developed by Pfizer and made in such a way that it protects liver cells from excessive apoptosis …

HPV-16 trojan peptide vaccine

HPV-16 trojan peptide vaccine is an investigational cancer immunotherapy consisting of a novel Trojan peptide complex, composed of human papilloma virus 16 (HPV 16) epitopes, to stimulate antigen-specific CD4 and CD8 T cell responses.
Investigational
Matched Description: … papilloma virus 16 (HPV 16) epitopes, to stimulate antigen-specific CD4 and CD8 T cell responses. ... is an investigational cancer immunotherapy consisting of a novel Trojan peptide complex, composed of human …

Palmidrol

A cannabinoid receptor-inactive eCB-related molecule used as prophylactic in helping to prevent respiratory viral infection. Palmidrol is available for human use as a supplement (400 mg capsules) and as food for medical purposes In Italy and Spain (300 mg and 600 mg tablets).
Experimental
Nutraceutical
Matched Description: … Palmidrol is available for human use as a supplement (400 mg capsules) and as food for medical purposes ... In Italy and Spain (300 mg and 600 mg tablets). …
Matched Categories: … Cannabinoids and similars ... Hormones, Hormone Substitutes, and Hormone Antagonists …

XTL-6865

XTL-6865 is a combination of two fully human monoclonal antibodies (Ab68 and Ab65) against the hepatitis C virus E2 envelope protein. It is being developed to prevent HCV re-infection following a liver transplant and for the treatment of chronic HCV disease.
Investigational
Matched Description: … XTL-6865 is a combination of two fully human monoclonal antibodies (Ab68 and Ab65) against the hepatitis ... It is being developed to prevent HCV re-infection following a liver transplant and for the treatment …

Gavocabtagene autoleucel

Gavocabtagene autoleucel is a novel cell therapy consisting of autologous genetically engineered T cells expressing a single-domain antibody that recognizes human Mesothelin, fused to the CD3-epsilon subunit which, upon expression, is incorporated into the endogenous T cell receptor (TCR) complex.
Investigational
Matched Description: … consisting of autologous genetically engineered T cells expressing a single-domain antibody that recognizes human …

RGX-501

RGX-501 is an adeno-associated virus vector 8 (AAV8)-mediated gene therapy that delivers a functional copy of the human low-density lipoprotein receptor (LDLR) gene to liver cells. It is being investigated for the treatment of homozygous familial hypercholesterolemia.
Investigational
Matched Description: … adeno-associated virus vector 8 (AAV8)-mediated gene therapy that delivers a functional copy of the human …

Viralym-C

Viralym-C is an investigational T-cell immunotherapy developed by ViraCyte. It consists of Human Leukocyte Antigen (HLA)-matched cytomegalovirus (CMV)-specific T lymphocytes. It was granted FDA orphan designation in January 2017 and investigated for the treatment of CMV infection.[A260291, L47241]
Investigational
Matched Description: … It consists of Human Leukocyte Antigen (HLA)-matched cytomegalovirus (CMV)-specific T lymphocytes. ... It was granted FDA orphan designation in January 2017 and investigated for the treatment of CMV infection …

CT-011

CT-011 is a humanized monoclonal antibody directed against a B7 family-associated protein, in patients with advanced haematological malignancies. It is directed against human PD-1 (programmed cell death 1; PDCD1), with immunomodulating and antitumor activities.
Investigational
Matched Description: … It is directed against human PD-1 (programmed cell death 1; PDCD1), with immunomodulating and antitumor …
Matched Categories: … Amino Acids, Peptides, and Proteins …

NN344

NN344 is a neutral, soluble long-acting human insulin analogue with 24 hour coverage by once daily injection. NN344 has a very flat and predictable action profile. The product is intended for basal insulin treatment of diabetes mellitus.
Investigational
Matched Description: … NN344 has a very flat and predictable action profile. ... NN344 is a neutral, soluble long-acting human insulin analogue with 24 hour coverage by once daily injection …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …

PI-166

PI-166 is a small organic compound with specific avidity to liver cancer cells. It has demonstrated the ability to reduce the growth of rat hepatomas, which is like human hepatomas, are resistant to established anti-cancer agents.
Investigational
Matched Description: … It has demonstrated the ability to reduce the growth of rat hepatomas, which is like human hepatomas, …

Mito-4509

Mito-4509 is a non-feminizing estrogen analog that could affect mitochondrial metabolic pathways. It is used to treat Parkinson's Disease, Alzheimer's Disease, Retinal Disorders and other neurologic Disorders.
Investigational
Matched Description: … It is used to treat Parkinson's Disease, Alzheimer's Disease, Retinal Disorders and other neurologic …

Sibrotuzumab

Sibrotuzumab is a humanized monoclonal antibody directed against fibroblast activation protein (FAP). It is used to treat cancer.
Investigational
Matched Categories: … Amino Acids, Peptides, and Proteins …

MLN8054

MLN8054 has been used in trials studying the treatment of Colon Neoplasm, Breast Neoplasm, Bladder Neoplasm, Pancreatic Neoplasm, and Advanced Malignancies.
Investigational
Matched Description: … trials studying the treatment of Colon Neoplasm, Breast Neoplasm, Bladder Neoplasm, Pancreatic Neoplasm, and …

Dociparstat sodium

Investigational
Matched Categories: … Heparin and similars …

Icaridin

Icaridin, also known as Picaridin or hydroxy-ethyl isobutyl piperidine carboxylate, is a cyclic amine and a member of the piperidine chemical family. Piperidines are structural components of piperine, which is a plant extract from the genus _Piper _, or pepper. Icaridin has been commonly used as a topically-applied insect repellent...
Experimental
Matched Description: … Icaridin, also known as Picaridin or hydroxy-ethyl isobutyl piperidine carboxylate, is a cyclic amine and ... repellent by the Public Health Agency of Canada’s Canadian Advisory Committee on Tropical Medicine and ... insect repellent in various countries but was officially licensed for use in the United States in 2001 and …

CEP-1347

CEP-1347 is a semi-synthetic compound shown to protect multiple nerve cell types from a variety of insults leading to programmed cell death (apoptosis) which could improve the survival of dopamine neurons prior to and after transplantation.
Investigational
Matched Description: … to programmed cell death (apoptosis) which could improve the survival of dopamine neurons prior to and …

AI-128

AI-128 is the first human demonstration of sustained release drug administration in the lung. AI-128 consists of slowly dissolving microspheres designed to control where drug particles go in the lung and how quickly they release their drug.
Investigational
Matched Description: … AI-128 is the first human demonstration of sustained release drug administration in the lung. ... consists of slowly dissolving microspheres designed to control where drug particles go in the lung and …

Dacetuzumab

Dacetuzumab has been used in trials studying the treatment of Multiple Myeloma, Non-Hodgkin Lymphoma, Leukemia, Lymphocytic, Chronic, and Lymphoma, Large B-Cell, Diffuse. It is a humanized anti-CD40 antibody and induces cytotoxicity in human multiple myeloma cells.
Investigational
Matched Description: … It is a humanized anti-CD40 antibody and induces cytotoxicity in human multiple myeloma cells. ... trials studying the treatment of Multiple Myeloma, Non-Hodgkin Lymphoma, Leukemia, Lymphocytic, Chronic, and …
Matched Categories: … Amino Acids, Peptides, and Proteins …

GI-101

GI-101 is a bi-specific fragment crystallizable region (Fc) fusion protein containing a cluster of differentiation 80 ectodomain as an N-terminal moiety and interleukin-2 variant as a C-terminal moiety conjugated with human immunoglobulin G4 Fc.
Investigational
Matched Description: … interleukin-2 variant as a C-terminal moiety conjugated with human immunoglobulin G4 Fc. ... region (Fc) fusion protein containing a cluster of differentiation 80 ectodomain as an N-terminal moiety and …

Arbaclofen Placarbil

Arbaclofen Placerbil is a prodrug of Arbaclofen, which is a selective gamma-amino-butyric acid type B receptor agonist and the R-enantiomer of baclofen. It was discovered, and has been patented by XenoPort as a new chemical entity with an improved pharmacokinetic profile compared to baclofen, which allows for sustained release properties....
Investigational
Matched Description: … Placerbil is a prodrug of Arbaclofen, which is a selective gamma-amino-butyric acid type B receptor agonist and ... It was discovered, and has been patented by XenoPort as a new chemical entity with an improved pharmacokinetic ... Placerbil was believed to have therapeutic potential in treating gastroesophogeal reflux disease (GERD) and …

VPM4001

VPM4001 is an allogeneic vaccine for treatment of prostate carcinoma. It consists of irradiated human LNCaP cells that have been genetically modified to permanently secrete interferon-γ and interleukin-2 (LNCaP/IL-2/IFN-γ). Interferon-γ enhances presentation of tumour antigens, whereas interleukin-2 stimulates T cells.
Investigational
Matched Description: … interferon-γ and interleukin-2 (LNCaP/IL-2/IFN-γ). ... It consists of irradiated human LNCaP cells that have been genetically modified to permanently secrete …

SCIB1

SCIB1 is an investigational cancer vaccine being developed by Scancell Ltd. It is being investigated for the treatment of melanoma. It consists of plasmid DNA molecules that express a modified antibody in human cells, working to stimulate the patient's T cells to have a stronger reaction against melanoma cells.
Investigational
Matched Description: … It consists of plasmid DNA molecules that express a modified antibody in human cells, working to stimulate …

Sar9, Met (O2)11-Substance P

Sar9, Met (O2)11-Substance P is a neurokinin-1 receptor agonist. It is an analog of the naturally occurring human neuropeptide Substance P, which can be found throughout the body, including in the airways of humans and many other species.
Investigational
Matched Description: … the body, including in the airways of humans and many other species. ... It is an analog of the naturally occurring human neuropeptide Substance P, which can be found throughout …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …

BBM-H803

BBM-H803 is a recombinant adeno-associated virus (AAV) based gene therapy drug for hemophilia A developed and manufactured by Belief BioMed. It consists of an adeno-associated virus vector containing an expression cassette of the human Factor VIII transgene.
Investigational
Matched Description: … It consists of an adeno-associated virus vector containing an expression cassette of the human Factor ... BBM-H803 is a recombinant adeno-associated virus (AAV) based gene therapy drug for hemophilia A developed and …
Displaying drugs 1776 - 1800 of 1990 in total