Displaying drugs 1851 - 1875 of 2435 in total
Lymecycline
Lymecycline is a broad-spectrum second-generation tetracycline antibiotic used for the treatment of acne and other susceptible bacterial infections.[L13880,L13883] It has been proven a cost-effective alternative to treatment with minocycline with comparable safety and efficacy. Lymecycline was initially discovered in 1961. It is marketed by Galderma and used in the UK...
Approved
Investigational
Matched Synonyms: … N-Lysinomethyltetracycline ... N2-(((+)-5-Amino-5-carboxypentylamino)methyl)tetracycline ... N6-((4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo- …
Matched Description: … It is marketed by Galderma and used in the UK as well as New Zealand in addition to other countries. ... and [tetracycline]. ... Lymecycline is a broad-spectrum second-generation tetracycline antibiotic used for the treatment of acne and …
Matched Description: … It is marketed by Galderma and used in the UK as well as New Zealand in addition to other countries. ... and [tetracycline]. ... Lymecycline is a broad-spectrum second-generation tetracycline antibiotic used for the treatment of acne and …
(6R)-Folinic acid
Experimental
Matched Synonyms: … L-Glutamic acid, N-[4-[[[(6R)-2-amino-5-formyl-3,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl]methyl]amino] ... N-{[4-({[(6R)-2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)phenyl]carbonyl} …
Matched Categories: … Folic Acid and Derivatives …
Matched Categories: … Folic Acid and Derivatives …
Lotilaner
Lotilaner is an ectoparasiticide that is a member of the isoxazoline family of compounds. Lotilaner has largely been used for veterinary uses as an antiparasitic agent to treat flea and tick infestations in animals.[A260746, L47556] Lotilaner consists of two enantiomers: the S-enantiomer is active in vivo, while the R-enantiomer is...
Approved
Vet approved
Matched Synonyms: … thiophenecarboxamide, 5-((5s)-4,5-dihydro-5-(3,4,5-trichlorophenyl)-5-(trifluoromethyl)-3-isoxazolyl)-3-methyl-n- ... 3-methyi-n-(2-oxo-2-((2,2,2-trifluoroethyl)amino)ethyl)-5-((55)-5-(3,4,5-trichlorophenyl)-5-(trifluoromethyl …
Matched Iupac: … -5-(3,4,5-trichlorophenyl)-5-(trifluoromethyl)-4,5-dihydro-1,2-oxazol-3-yl]thiophen-2-yl}formamido)-N- …
Matched Description: … L47546] Lotilaner has largely been used for veterinary uses as an antiparasitic agent to treat flea and ... 2023, lotilaner was approved by the FDA for the treatment of Demodex blepharitis, making it the first and …
Matched Categories: … Scabicides, Insecticides and Repellents …
Matched Iupac: … -5-(3,4,5-trichlorophenyl)-5-(trifluoromethyl)-4,5-dihydro-1,2-oxazol-3-yl]thiophen-2-yl}formamido)-N- …
Matched Description: … L47546] Lotilaner has largely been used for veterinary uses as an antiparasitic agent to treat flea and ... 2023, lotilaner was approved by the FDA for the treatment of Demodex blepharitis, making it the first and …
Matched Categories: … Scabicides, Insecticides and Repellents …
Chamomile
Chamomile is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Investigational
Matched Synonyms: … Chamomile Tea …
Matched Description: … It is not an approved drug. …
Matched Description: … It is not an approved drug. …
Cirtuvivint
Cirtuvivint is a first-in-class CDC-like kinase (CLK) inhibitor.
Investigational
Matched Synonyms: … 4-pyridinecarboxamide, 2-(4-methyl-1-piperazinyl)-n-(6-(1-methyl-1h-pyrazol-4-yl)-3-isoquinolinyl)- …
Matched Iupac: … N-[6-(1-methyl-1H-pyrazol-4-yl)isoquinolin-3-yl]-2-(4-methylpiperazin-1-yl)pyridine-4-carboxamide …
Matched Iupac: … N-[6-(1-methyl-1H-pyrazol-4-yl)isoquinolin-3-yl]-2-(4-methylpiperazin-1-yl)pyridine-4-carboxamide …
IMT-288
IMT-288 is under investigation in clinical trial NCT01730638 (Immunotep for Patients With Medullary Thyroid Carcinoma.).
Investigational
Matched Synonyms: … D-LYSINAMIDE, N-((4,7,10-TRIS(CARBOXYMETHYL)-1,4,7,10-TETRAAZACYCLODODEC-1-YL)ACETYL)-D-TYROSYL-N6-(N ... -GLUTAMYL-N6-(N-(4-((2-(1H-IMIDAZOL-4-YL)ETHYL)AMINO)-1,4-DIOXOBUTYL)GLYCY …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Ceclazepide
Investigational
Matched Synonyms: … -3-yl)-n'-(3-(methylamino)phenyl)- ... Urea, n-((3r)-1-(4-(acetyloxy)-3,3-dimethyl-2-oxobutyl)-2,3-dihydro-2-oxo-5-(2-pyridinyl)-1h-1,4-benzodiazepin …
TSN-084
Investigational
Matched Synonyms: … 3-PYRIDINECARBOXAMIDE, N-(3-FLUORO-4-((1-METHYL-6-(1H-PYRAZOL-4-YL)-1H-INDAZOL-5-YL)OXY)PHENYL)-1-(4- ... N-[3-fluoro-4-[[1-methyl-6-(1H-pyrazol-4-yl)-1H-indazol-5-yl]oxy]phenyl]-1-(4-fluorophenyl)-1,2-dihydro …
Matched Iupac: … N-(3-fluoro-4-{[1-methyl-6-(1H-pyrazol-4-yl)-1H-indazol-5-yl]oxy}phenyl)-1-(4-fluorophenyl)-2-oxo-6-( …
Matched Iupac: … N-(3-fluoro-4-{[1-methyl-6-(1H-pyrazol-4-yl)-1H-indazol-5-yl]oxy}phenyl)-1-(4-fluorophenyl)-2-oxo-6-( …
Rezatapopt
Rezatapopt is under investigation in clinical trial NCT04585750 (The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)).
Investigational
Matched Synonyms: … -methyl-4-piperidinyl]amino]-1-(2,2,2-trifluoroethyl)-1H-indol-2-yl]-2-propyn-1-yl]amino]-3-methoxy-N-methyl ... -methyl-4-piperidinyl]amino]-1-(2,2,2-trifluoroethyl)-1H-indol-2-yl]-2-propyn-1-yl]amino]-3-methoxy-N-methylbenzamide …
Birabresib
Birabresib is under investigation in clinical trial NCT02698176 (A Dose Exploration Study With MK-8628 in Participants With Selected Advanced Solid Tumors (MK-8628-006)).
Investigational
Matched Synonyms: … 6S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thienol[3,2,-f]-[1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl]-N- …
Matched Iupac: … 4,5,13-trimethyl-3-thia-1,8,11,12-tetraazatricyclo[8.3.0.0^{2,6}]trideca-2(6),4,7,10,12-pentaen-9-yl]-N- …
Matched Iupac: … 4,5,13-trimethyl-3-thia-1,8,11,12-tetraazatricyclo[8.3.0.0^{2,6}]trideca-2(6),4,7,10,12-pentaen-9-yl]-N- …
Cemdomespib
Cemdomespib is under investigation in clinical trial NCT05895552 (A Phase 2 Study of RTA 901 in Patients With Diabetic Peripheral Neuropathic Pain (CYPRESS)).
Investigational
Matched Synonyms: … Acetamide, n-(2-(5-((6-deoxy-5-c-methyl-4-o-methyl-.alpha. …
Bimatoprost
Bimatoprost, also known as Latisse or Lumigan, belongs to a group of drugs called prostamides, which are synthetic structural analogs of prostaglandin. Bimatoprost, marketed by Allergan, is administered in both the ophthalmic solution and implant form. It has the ability to reduce ocular hypotension, proving effective in conditions such as...
Approved
Investigational
Matched Synonyms: … (Z)-7-((1R,2R,3R,5S)-3,5-Dihydroxy-2-((1E,3S)-3-hydroxy-5-phenyl-1-pentenyl)cyclopentyl)-N-ethyl-5-heptenamide …
Matched Iupac: … (5Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenylpent-1-en-1-yl]cyclopentyl]-N-ethylhept …
Matched Description: … Bimatoprost, marketed by Allergan, is administered in both the ophthalmic solution and implant form. ... the ability to reduce ocular hypotension, proving effective in conditions such as ocular hypertension and ... [L6910] It was initially approved by the FDA in 2001 for ocular hypertension and later approved for hypothrichosis …
Matched Categories: … Antiglaucoma Preparations and Miotics …
Matched Iupac: … (5Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenylpent-1-en-1-yl]cyclopentyl]-N-ethylhept …
Matched Description: … Bimatoprost, marketed by Allergan, is administered in both the ophthalmic solution and implant form. ... the ability to reduce ocular hypotension, proving effective in conditions such as ocular hypertension and ... [L6910] It was initially approved by the FDA in 2001 for ocular hypertension and later approved for hypothrichosis …
Matched Categories: … Antiglaucoma Preparations and Miotics …
Ximelagatran
Ximelagatran is an anticoagulant intended to become a replacement for warfarin by overcoming the dietary restrictions, drug interaction, and monitoring issues associated with the former. In 2006, its manufacturer AstraZeneca announced that it would not attempt to market ximelagatran after reports of hepatotoxicity (liver damage) during trials, and to discontinue...
Approved
Investigational
Withdrawn
Matched Synonyms: … ethyl 2-[[(1R)-1-cyclohexyl-2- [(2S)-2-[[4-(N'-hydroxycarbamimidoyl) phenyl]methylcarbamoyl]azetidin- …
Matched Iupac: … ethyl 2-{[(1R)-1-cyclohexyl-2-[(2S)-2-[({4-[(Z)-N'-hydroxycarbamimidoyl]phenyl}methyl)carbamoyl]azetidin …
Matched Description: … intended to become a replacement for warfarin by overcoming the dietary restrictions, drug interaction, and ... reports of hepatotoxicity (liver damage) during trials, and to discontinue its distribution in countries ... In 2006, its manufacturer AstraZeneca announced that it would not attempt to market ximelagatran after …
Matched Categories: … Blood and Blood Forming Organs …
Matched Iupac: … ethyl 2-{[(1R)-1-cyclohexyl-2-[(2S)-2-[({4-[(Z)-N'-hydroxycarbamimidoyl]phenyl}methyl)carbamoyl]azetidin …
Matched Description: … intended to become a replacement for warfarin by overcoming the dietary restrictions, drug interaction, and ... reports of hepatotoxicity (liver damage) during trials, and to discontinue its distribution in countries ... In 2006, its manufacturer AstraZeneca announced that it would not attempt to market ximelagatran after …
Matched Categories: … Blood and Blood Forming Organs …
ABT-737
An inhibitor of members of the Bcl‑2 family of apoptosis regulators.
Investigational
Matched Synonyms: … Benzamide, 4-(4-((4'-chloro(1,1'-biphenyl)-2-yl)methyl)-1-piperazinyl)-n-((4-(((1r)-3-(dimethylamino) …
Matched Iupac: … 4-[4-({4'-chloro-[1,1'-biphenyl]-2-yl}methyl)piperazin-1-yl]-N-(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl …
Matched Iupac: … 4-[4-({4'-chloro-[1,1'-biphenyl]-2-yl}methyl)piperazin-1-yl]-N-(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl …
Elranatamab
Elranatamab is a bispecific B-cell maturation antigen (BCMA)-directed CD3 T-cell engager. It is a humanized immunoglobulin 2-alanine kappa antibody derived from two monoclonal antibodies (mAbs), an anti-BCMA mAb and an anti-CD3 mAb, each of which contributes one heavy chain and one light chain to drug structure. The resulting 4-chain bispecific...
Approved
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G2 (224-ARGININE,265-ALANINE,330-SERINE,331-SERINE), ANTI-(HUMAN CD3 ANTIGEN .EPSILON. …
Matched Description: … immunoglobulin 2-alanine kappa antibody derived from two monoclonal antibodies (mAbs), an anti-BCMA mAb and ... an anti-CD3 mAb,[A261060] each of which contributes one heavy chain and one light chain to drug structure …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … immunoglobulin 2-alanine kappa antibody derived from two monoclonal antibodies (mAbs), an anti-BCMA mAb and ... an anti-CD3 mAb,[A261060] each of which contributes one heavy chain and one light chain to drug structure …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Gandotinib
Gandotinib has been used in trials studying the treatment of Myelofibrosis, Polycythemia Vera, Primary Myelofibrosis, Thrombocythemia, Essential, and Myeloproliferative Disorders, among others.
Investigational
Matched Synonyms: … 3-(4-CHLORO-2-FLUOROBENZYL)-2-METHYL-N-(5-METHYL-1H-PYRAZOL-3-YL)-8- (MORPHOLINOMETHYL)IMIDAZO(1,2-B) ... IMIDAZO(1,2-B)PYRIDAZIN-6-AMINE, 3-((4-CHLORO-2-FLUOROPHENYL)METHYL)-2-METHYL-N-(5- METHYL-1H-PYRAZOL …
Matched Iupac: … N-{3-[(4-chloro-2-fluorophenyl)methyl]-2-methyl-8-[(morpholin-4-yl)methyl]imidazo[1,2-b]pyridazin-6-yl …
Matched Description: … the treatment of Myelofibrosis, Polycythemia Vera, Primary Myelofibrosis, Thrombocythemia, Essential, and …
Matched Iupac: … N-{3-[(4-chloro-2-fluorophenyl)methyl]-2-methyl-8-[(morpholin-4-yl)methyl]imidazo[1,2-b]pyridazin-6-yl …
Matched Description: … the treatment of Myelofibrosis, Polycythemia Vera, Primary Myelofibrosis, Thrombocythemia, Essential, and …
gamma-Hydroxybutyric acid
Gamma hydroxybutyric acid, commonly abbreviated GHB, is a therapeutic drug which is illegal in multiple countries. It is currently regulated in the US and sold by Jazz Pharmaceuticals under the name Xyrem. However, it is important to note that GHB is a designated Orphan drug (in 1985). Today Xyrem is...
Approved
Illicit
Investigational
Matched Synonyms: … oxy-n-butyric acid …
Matched Description: … and almost all other living creatures in small amounts. ... It is currently regulated in the US and sold by Jazz Pharmaceuticals under the name Xyrem. ... Today Xyrem is a Schedule III drug; however GHB remains a Schedule I drug and the illicit use of Xyrem …
Matched Description: … and almost all other living creatures in small amounts. ... It is currently regulated in the US and sold by Jazz Pharmaceuticals under the name Xyrem. ... Today Xyrem is a Schedule III drug; however GHB remains a Schedule I drug and the illicit use of Xyrem …
Lufenuron
Lufenuron is used in veterinary for the control of flea.
Experimental
Vet approved
Matched Synonyms: … N-({[2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl]amino}carbonyl)-2,6-difluorobenzamide …
N-{4-[(Carboxymethyl)carbamoyl]benzoyl}-L-valyl-N-[(3S)-1,1,1-trifluoro-4-methyl-2-oxo-3-pentanyl]-L-prolinamide
Experimental
Matched Name: … N-{4-[(Carboxymethyl)carbamoyl]benzoyl}-L-valyl-N-[(3S)-1,1,1-trifluoro-4-methyl-2-oxo-3-pentanyl]-L-prolinamide …
N-(3-chlorophenyl)-N-methyl-2-oxo-3-[(3,4,5-trimethyl-1H-pyrrol-2-yl)methyl]-2H-indole-5-sulfonamide
Experimental
Matched Name: … N-(3-chlorophenyl)-N-methyl-2-oxo-3-[(3,4,5-trimethyl-1H-pyrrol-2-yl)methyl]-2H-indole-5-sulfonamide …
Matched Iupac: … N-(3-chlorophenyl)-N-methyl-2-oxo-3-[(3,4,5-trimethyl-1H-pyrrol-2-yl)methyl]-2H-indole-5-sulfonamide …
Matched Iupac: … N-(3-chlorophenyl)-N-methyl-2-oxo-3-[(3,4,5-trimethyl-1H-pyrrol-2-yl)methyl]-2H-indole-5-sulfonamide …
(3Z)-N,N-DIMETHYL-2-OXO-3-(4,5,6,7-TETRAHYDRO-1H-INDOL-2-YLMETHYLIDENE)-2,3-DIHYDRO-1H-INDOLE-5-SULFONAMIDE
Experimental
Matched Name: … (3Z)-N,N-DIMETHYL-2-OXO-3-(4,5,6,7-TETRAHYDRO-1H-INDOL-2-YLMETHYLIDENE)-2,3-DIHYDRO-1H-INDOLE-5-SULFONAMIDE …
Matched Iupac: … (3Z)-N,N-dimethyl-2-oxo-3-[(4,5,6,7-tetrahydro-1H-indol-2-yl)methylidene]-2,3-dihydro-1H-indole-5-sulfonamide …
Matched Iupac: … (3Z)-N,N-dimethyl-2-oxo-3-[(4,5,6,7-tetrahydro-1H-indol-2-yl)methylidene]-2,3-dihydro-1H-indole-5-sulfonamide …
N'-[(1E)-(3,5-dibromo-2,4-dihydroxyphenyl)methylidene]-4-methoxybenzohydrazide
Experimental
Matched Name: … N'-[(1E)-(3,5-dibromo-2,4-dihydroxyphenyl)methylidene]-4-methoxybenzohydrazide …
Matched Iupac: … N'-[(E)-(3,5-dibromo-2,4-dihydroxyphenyl)methylidene]-4-methoxybenzohydrazide …
Matched Iupac: … N'-[(E)-(3,5-dibromo-2,4-dihydroxyphenyl)methylidene]-4-methoxybenzohydrazide …
N-[(4-HYDROXY-8-IODOISOQUINOLIN-3-YL)CARBONYL]GLYCINE
Experimental
Matched Name: … N-[(4-HYDROXY-8-IODOISOQUINOLIN-3-YL)CARBONYL]GLYCINE …
3-cyclohexyl-D-alanyl-N-(3-chlorobenzyl)-L-prolinamide
Experimental
Matched Name: … 3-cyclohexyl-D-alanyl-N-(3-chlorobenzyl)-L-prolinamide …
Matched Iupac: … (2S)-1-[(2R)-2-amino-3-cyclohexylpropanoyl]-N-[(3-chlorophenyl)methyl]pyrrolidine-2-carboxamide …
Matched Iupac: … (2S)-1-[(2R)-2-amino-3-cyclohexylpropanoyl]-N-[(3-chlorophenyl)methyl]pyrrolidine-2-carboxamide …
N~3~-(3-PYRIDIN-3-YLBENZYL)PYRIDINE-2,3-DIAMINE
Experimental
Matched Name: … N~3~-(3-PYRIDIN-3-YLBENZYL)PYRIDINE-2,3-DIAMINE …
Matched Iupac: … N3-{[3-(pyridin-3-yl)phenyl]methyl}pyridine-2,3-diamine …
Matched Iupac: … N3-{[3-(pyridin-3-yl)phenyl]methyl}pyridine-2,3-diamine …
Displaying drugs 1851 - 1875 of 2435 in total