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Displaying drugs 1901 - 1925 of 2444 in total
Bisegliptin
Bisegliptin is a compound for the treatment of type 2 diabetes. It is an orally active, dipeptidyl peptidase-IV (DPPIV) inhibitor which lowers blood glucose levels by blocking the degradation of the hormone GLP-1 thereby stimulating glucose-dependent insulin secretion and lowering blood glucose levels without hypoglycemic effects.
Investigational
Matched Categories: … DPP-IV Inhibitors …
INCB-9471
INCB-9471 is a novel, orally available CCR5 antagonist that is part of a new class of drugs to treat HIV/AIDS. It is a potent, selective inhibitor of the HIV-1 virus.
Investigational
Matched Categories: … Receptors, CCR4, antagonists & inhibitors …
LB-100
LB-100 is under investigation in clinical trial NCT03886662 (A Study of LB-100 in Patients With Low or Intermediate-1 Risk Myelodysplastic Syndromes (MDS)).
Investigational
Matched Categories: … Enzyme Inhibitors …
PIK-75
PIK-75 is a preferential p110 alpha/gamma PI3K inhibitor.
Investigational
Matched Categories: … Phosphatidylinositol 3-Kinases, antagonists & inhibitors …
5'-S-methyl-5'-thioadenosine
Experimental
Matched Categories: … Enzyme Inhibitors ... Nucleic Acid Synthesis Inhibitors ... Protein O-Methyltransferase, antagonists & inhibitors …
Nitroaspirin
Nitroaspirin has been investigated for the treatment of Intermittent Claudication.
Investigational
Matched Categories: … Enzyme Inhibitors ... Protease Inhibitors ... Cysteine Proteinase Inhibitors …
Ibudilast
Ibudilast is an anti-inflammatory and neuroprotective oral agent which shows an excellent safety profile at 60 mg/day and provides significantly prolonged time-to-first relapse and attenuated brain volume shrinkage in patients with relapsing-remitting (RR) and/or secondary progressive (SP) multiple sclerosis (MS). Ibudilast is currently in development in the U.S. (codes: AV-411...
Investigational
Matched Categories: … Enzyme Inhibitors ... Phosphodiesterase Inhibitors ... Phosphodiesterase 5 Inhibitors …
Lorvotuzumab mertansine
Lorvotuzumab mertansine has been used in trials studying the treatment of SCLC, Leukemia, Ovarian Cancer, Multiple Myeloma, and Merkel Cell Carcinoma, among others.
Investigational
Matched Categories: … Cytochrome P-450 CYP3A Inhibitors ... Cytochrome P-450 CYP3A4 Inhibitors ... Cytochrome P-450 Enzyme Inhibitors ... Cytochrome P-450 CYP3A4 Inhibitors (strength unknown) …
Piritrexim
Piritrexim has been used in trials studying the treatment of Bladder Cancer, Urethral Cancer, and Transitional Cell Cancer of the Renal Pelvis and Ureter.
Investigational
Matched Categories: … Enzyme Inhibitors …
Managlinat dialanetil
CS-917 is a novel inhibitor of fructose 1,6-bisphphosphatase (FBPase) which is one of the rate-limiting enzymes of gluconeogenesis.
Investigational
Matched Categories: … Fructose-Bisphosphatase, antagonists & inhibitors …
MLN8054
MLN8054 has been used in trials studying the treatment of Colon Neoplasm, Breast Neoplasm, Bladder Neoplasm, Pancreatic Neoplasm, and Advanced Malignancies.
Investigational
Matched Categories: … Protein Kinase Inhibitors …
SB-1578
SB-1578 is under investigation in clinical trial NCT01235871 (A Single and Multiple-Dose Study of SB1578).
Investigational
Matched Categories: … fms-Like Tyrosine Kinase 3, antagonists & inhibitors …
JNJ-28312141
Investigational
Matched Categories: … Receptors, Colony-Stimulating Factor, antagonists & inhibitors …
Salirasib
Salirasib has been used in trials studying the diagnostic of Carcinoma, Non-Small-Cell Lung.
Investigational
Matched Categories: … Enzyme Inhibitors ... Calcium-Calmodulin-Dependent Protein Kinases, antagonists & inhibitors …
Hyperforin
Hyperforin is a phytochemical generated by the plants of the Hypericum family. One of the most important members of this family, due to its medical properties, is Hypericum perforatum, also known as St John's wort.
Nutraceutical
Matched Categories: … OATP1B1/SLCO1B1 Inhibitors …
Irosustat
Irosustat has been investigated for the treatment of Metastatic Breast Cancer and Locally Advanced Breast Cancer.
Investigational
Matched Categories: … Steryl-Sulfatase, antagonists & inhibitors …
Displaying drugs 1901 - 1925 of 2444 in total