Displaying drugs 1926 - 1950 of 2585 in total
Gefitinib
Gefitinib (originally coded ZD1839) is a drug used in the treatment of certain types of cancer. Acting in a similar manner to erlotinib (marketed as Tarceva), gefitinib selectively targets the mutant proteins in malignant cells. It is marketed by AstraZeneca under the trade name Iressa.
Approved
Investigational
Matched Synonyms: … N-(3-chloro-4-fluorophenyl)-7-methoxy-6-(3-(4-morpholinyl)propoxy)-4-quinazolinamine …
Matched Iupac: … N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[3-(morpholin-4-yl)propoxy]quinazolin-4-amine …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … Nat-gefitinib …
Matched Iupac: … N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[3-(morpholin-4-yl)propoxy]quinazolin-4-amine …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … Nat-gefitinib …
Lisinopril
Lisinopril is an angiotensin converting enzyme inhibitor (ACEI) used to treat hypertension, heart failure, and myocardial infarction.[L8384,L8387,L8390] Lisinopril and captopril are the only ACEIs that are not prodrugs. It functions by inhibition of angiotensin converting enzyme as well as the renin angiotensin aldosterone system.[A184781,A184808,A184817] ACEIs are commonly used as a...
Approved
Investigational
Matched Synonyms: … (S)-1-(N(2)-(1-Carboxy-3-phenylpropyl)-L-lysyl)-L-proline ... [N2-[(S)-1-carboxy-3-phenylpropyl]-L-lysyl-L-proline …
Matched Description: … [L8384,L8387,L8390] Lisinopril and [captopril] are the only ACEIs that are not prodrugs. ... Lisinopril is an angiotensin converting enzyme inhibitor (ACEI) used to treat hypertension, heart failure, and …
Matched Mixtures name: … Nu-lisinopril/hctz ... Nu-lisinopril/hctz ... Nu-lisinopril/hctz …
Matched Categories: … ACE Inhibitors and Calcium Channel Blockers ... ACE Inhibitors and Diuretics ... Amino Acids, Peptides, and Proteins ... lisinopril and diuretics ... lisinopril and amlodipine …
Matched Products: … Nu-lisinopril …
Matched Description: … [L8384,L8387,L8390] Lisinopril and [captopril] are the only ACEIs that are not prodrugs. ... Lisinopril is an angiotensin converting enzyme inhibitor (ACEI) used to treat hypertension, heart failure, and …
Matched Mixtures name: … Nu-lisinopril/hctz ... Nu-lisinopril/hctz ... Nu-lisinopril/hctz …
Matched Categories: … ACE Inhibitors and Calcium Channel Blockers ... ACE Inhibitors and Diuretics ... Amino Acids, Peptides, and Proteins ... lisinopril and diuretics ... lisinopril and amlodipine …
Matched Products: … Nu-lisinopril …
Ceritinib
Ceritinib is used for the treatment of adults with anaplastic lymphoma kinase (ALK)-positive metastatic non-small cell lung cancer (NSCLC) following failure (secondary to resistance or intolerance) of prior crizotinib therapy. About 4% of patients with NSCLC have a chromosomal rearrangement that generates a fusion gene between EML4 (echinoderm microtubule-associated protein-like...
Approved
Matched Synonyms: … N-{2-[(5-chloro-2-{[2-isopropoxy-5-methyl-4-(piperidin-4-yl)phenyl]amino}pyrimidin-4-yl)amino]phenyl} …
Matched Iupac: … 5-chloro-N2-[5-methyl-4-(piperidin-4-yl)-2-(propan-2-yloxy)phenyl]-N4-[2-(propane-2-sulfonyl)phenyl]pyrimidine …
Matched Description: … Ceritinib is used for the treatment of adults with anaplastic lymphoma kinase (ALK)-positive metastatic non-small ... lymphoma kinase), which results in constitutive kinase activity that contributes to carcinogenesis and ... rearrangement that generates a fusion gene between EML4 (echinoderm microtubule-associated protein-like 4) and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Iupac: … 5-chloro-N2-[5-methyl-4-(piperidin-4-yl)-2-(propan-2-yloxy)phenyl]-N4-[2-(propane-2-sulfonyl)phenyl]pyrimidine …
Matched Description: … Ceritinib is used for the treatment of adults with anaplastic lymphoma kinase (ALK)-positive metastatic non-small ... lymphoma kinase), which results in constitutive kinase activity that contributes to carcinogenesis and ... rearrangement that generates a fusion gene between EML4 (echinoderm microtubule-associated protein-like 4) and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Asundexian
Asundexian is under investigation in clinical trial NCT05686070 (A Study to Test Asundexian for Preventing a Stroke Caused by a Clot in Participants After an Acute Ischemic Stroke or After a High-risk Transient Ischemic Attack, a So-called Mini Stroke).
Investigational
Matched Synonyms: … 1(2h)-pyridineacetamide, n-(4-(aminocarbonyl)-3-fluorophenyl)-4-(5-chloro-2-(4-(trifluoromethyl)-1h-1,2,3 …
DSM-265
DSM265 has been used in trials studying the prevention and treatment of Malaria.
Investigational
Matched Synonyms: … 2-(1,1-difluoroethyl)-5-methyl-N-[4-(pentafluoro-lambda6-sulfanyl)phenyl]-[1,2,4]triazolo[1,5-a]pyrimidin ... 2-(1,1-Difluoroethyl)-5-methyl-N-[4-(pentafluoro-λ6-sulfanyl)phenyl][1,2,4]triazolo[1,5-a]pyrimidin-7 …
Matched Iupac: … 2-(1,1-difluoroethyl)-5-methyl-N-[4-(pentafluoro-lambda6-sulfanyl)phenyl]-[1,2,4]triazolo[1,5-a]pyrimidin …
Matched Description: … DSM265 has been used in trials studying the prevention and treatment of Malaria. …
Matched Iupac: … 2-(1,1-difluoroethyl)-5-methyl-N-[4-(pentafluoro-lambda6-sulfanyl)phenyl]-[1,2,4]triazolo[1,5-a]pyrimidin …
Matched Description: … DSM265 has been used in trials studying the prevention and treatment of Malaria. …
Midazolam
Midazolam is a short-acting hypnotic-sedative drug with anxiolytic, muscle relaxant, anticonvulsant, sedative, hypnotic, and amnesic properties. It belongs to a class of drugs called benzodiazepines. This drug is unique from others in this class due to its rapid onset of effects and short duration of action. Midazolam is available by...
Approved
Illicit
Matched Description: … and endoscopic procedures as pre-anesthetic medication, and as an adjunct to local anesthesia. ... short-acting hypnotic-sedative drug with anxiolytic, muscle relaxant, anticonvulsant, sedative, hypnotic, and ... This drug is unique from others in this class due to its rapid onset of effects and short duration of …
Matched Categories: … Benzodiazepine hypnotics and sedatives ... Hypnotics and Sedatives ... Benzodiazepines and benzodiazepine derivatives …
Matched Products: … N/a …
Matched Categories: … Benzodiazepine hypnotics and sedatives ... Hypnotics and Sedatives ... Benzodiazepines and benzodiazepine derivatives …
Matched Products: … N/a …
Talc
Talc is a mineral composed primarily of magnesium, silicon and oxygen. It is a substance often found in cosmetic and personal hygiene products including baby powder, adult body powders and facial powders. Talc helps absorb moisture, freshen materials, and reduce friction to prevent rashes.
Although talc has been widely used...
Approved
Matched Description: … body powders and facial powders. ... Talc is a mineral composed primarily of magnesium, silicon and oxygen. ... It is a substance often found in cosmetic and personal hygiene products including baby powder, adult …
Matched Mixtures name: … Foot and Body Powder …
Matched Products: … Natures Choice Baby …
Matched Mixtures name: … Foot and Body Powder …
Matched Products: … Natures Choice Baby …
Carba-nicotinamide-adenine-dinucleotide
Experimental
Matched Name: … Carba-nicotinamide-adenine-dinucleotide …
CA-074 methyl ester
CA-074 methyl ester (CA-074Me) is a cell-permeable cathepsin B inhibitor. It is converted by cellular esterases to CA-074.[A258234,A258239]
Experimental
Matched Synonyms: … Methyl N-({(2s,3s)-3-[(propylamino)carbonyl]oxiran-2-Yl}carbonyl)-L-isoleucyl-L-prolinate ... L-Proline, N-[[(2S,3S)-3-[(propylamino)carbonyl]oxiranyl]carbonyl]-L-isoleucyl-, methyl ester ... L-Proline, 1-[N-[[3-[(propylamino)carbonyl]oxiranyl]carbonyl]-L-isoleucyl]-, methyl ester, (2S-trans) …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Zilucoplan
Zilucoplan is a 15 amino-acid, synthetic macrocyclic peptide. It is a complement inhibitor that works to prevent the activation of C5, which is a complement protein involved in the innate immune system to initiate inflammatory responses. On October 17, 2023, zilucoplan gained its first FDA approval for the treatment of...
Approved
Matched Synonyms: … -ASPARTYL-N-METHYL-L-.ALPHA. ... -ASPARTYL-N-METHYL-L-.ALPHA.-ASPARTYL-3-METHYL- ... -GLUTAMYL-L-TYROSYL-L-PROLYL-(2S)-2-CYCLOHEXYLGLYCYL-N6-(3 …
Matched Iupac: … carboxyethyl)-22-acetamido-3,6,9,12,16,23-hexaoxo-2-(propan-2-yl)-1,4,7,10,13,17-hexaazacyclotricosan-14-yl]-N-methylformamido …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Iupac: … carboxyethyl)-22-acetamido-3,6,9,12,16,23-hexaoxo-2-(propan-2-yl)-1,4,7,10,13,17-hexaazacyclotricosan-14-yl]-N-methylformamido …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
SRX-246
Investigational
Matched Synonyms: … .-((3s,4r)-2-oxo-3-((4s)-2-oxo-4-phenyl-3-oxazolidinyl)-4-((1e)-2-phenylethenyl)-1-azetidinyl)-n-((1r ... .-((3s,4r)-2-oxo-3-((4s)-2-oxo-4-phenyl-3-oxazolidinyl)-4-((1e)-2-phenylethenyl)-1-azetidinyl)-n-((1r ... .-((3s,4r)-2-oxo-3-((4s)-2-oxo-4-phenyl-3-oxazolidinyl)-4-((1e)-2-phenylethenyl)-1-azetidinyl)-n-((1r …
Matched Iupac: … 2-[(3S,4R)-2-oxo-3-[(4S)-2-oxo-4-phenyl-1,3-oxazolidin-3-yl]-4-[(1E)-2-phenylethenyl]azetidin-1-yl]-N- …
Matched Iupac: … 2-[(3S,4R)-2-oxo-3-[(4S)-2-oxo-4-phenyl-1,3-oxazolidin-3-yl]-4-[(1E)-2-phenylethenyl]azetidin-1-yl]-N- …
Clofarabine
Clofarabine is a purine nucleoside antimetabolite that is being studied in the treatment of cancer. It is marketed as Clolar in the U.S. and Canada, or Evoltra in Europe, Australia, and New Zealand. Clofarabine is used in paediatrics to treat a type of leukaemia called relapsed or refractory acute lymphoblastic...
Approved
Investigational
Matched Synonyms: … 2-chloro-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)adenine ... 2-chloro-9-(2'-deoxy-2'-fluoro-β-D-arabinofuranosyl)adenine …
Matched Description: … It is marketed as Clolar in the U.S. and Canada, or Evoltra in Europe, Australia, and New Zealand. ... It is not known if the drug extends life expectancy. ... Its potential use in acute myeloid leukaemia (AML) and juvenile myelomonocytic leukaemia (JMML) has been …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Adenine Nucleotides ... Nucleic Acids, Nucleotides, and Nucleosides …
Matched Description: … It is marketed as Clolar in the U.S. and Canada, or Evoltra in Europe, Australia, and New Zealand. ... It is not known if the drug extends life expectancy. ... Its potential use in acute myeloid leukaemia (AML) and juvenile myelomonocytic leukaemia (JMML) has been …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Adenine Nucleotides ... Nucleic Acids, Nucleotides, and Nucleosides …
Torasemide
Torasemide is a high-ceiling loop diuretic. Structurally, it is a pyridine-sulfonylurea used as an antihypertensive agent. Torasemide was first approved for clinical use by the FDA in 1993.
Approved
Matched Synonyms: … N-(((1-Methylethyl)amino)carbonyl)-4-((3-methylphenyl)amino)-3-pyridinesulfonamide …
Matched Categories: … Non Potassium Sparing Diuretics …
Matched Products: … TORASEMID HEU 5MG NET ... TORASEMID HEU 10MG NET ... SUTRIL NEO 10 MG UZATILMIŞ SALIMLI TABLET,15 ADET …
Matched Categories: … Non Potassium Sparing Diuretics …
Matched Products: … TORASEMID HEU 5MG NET ... TORASEMID HEU 10MG NET ... SUTRIL NEO 10 MG UZATILMIŞ SALIMLI TABLET,15 ADET …
Navitoclax
Navitoclax has been used in trials studying the treatment and basic science of Solid Tumors, Non-Hodgkin's Lymphoma, EGFR Activating Mutation, Chronic Lymphoid Leukemia, and Hematological Malignancies, among others.
Navitoclax is an orally bioavailable small molecule inhibitor of Bcl-2 family proteins. It is a substance being studied in the treatment of...
Investigational
Matched Synonyms: … (R)-4-(3-Morpholin-4-Yl-1-Phenylsulfanylmethyl-Propylamino)-N-(4-{4-[2-(4-Chlorophenyl)-5,5-Dimethylcyclohex …
Matched Iupac: … 4-(4-{[2-(4-chlorophenyl)-5,5-dimethylcyclohex-1-en-1-yl]methyl}piperazin-1-yl)-N-(4-{[(2R)-4-(morpholin …
Matched Description: … Navitoclax has been used in trials studying the treatment and basic science of Solid Tumors, Non-Hodgkin's ... Lymphoma, EGFR Activating Mutation, Chronic Lymphoid Leukemia, and Hematological Malignancies, among ... It is a substance being studied in the treatment of lymphomas and other types of cancer. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Iupac: … 4-(4-{[2-(4-chlorophenyl)-5,5-dimethylcyclohex-1-en-1-yl]methyl}piperazin-1-yl)-N-(4-{[(2R)-4-(morpholin …
Matched Description: … Navitoclax has been used in trials studying the treatment and basic science of Solid Tumors, Non-Hodgkin's ... Lymphoma, EGFR Activating Mutation, Chronic Lymphoid Leukemia, and Hematological Malignancies, among ... It is a substance being studied in the treatment of lymphomas and other types of cancer. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
(1S,5S,7R)-N~7~-(BIPHENYL-4-YLMETHYL)-N~3~-HYDROXY-6,8-DIOXA-3-AZABICYCLO[3.2.1]OCTANE-3,7-DICARBOXAMIDE
Experimental
Matched Name: … (1S,5S,7R)-N~7~-(BIPHENYL-4-YLMETHYL)-N~3~-HYDROXY-6,8-DIOXA-3-AZABICYCLO[3.2.1]OCTANE-3,7-DICARBOXAMIDE …
Matched Iupac: … (1S,5S,7R)-N7-({[1,1'-biphenyl]-4-yl}methyl)-N3-hydroxy-6,8-dioxa-3-azabicyclo[3.2.1]octane-3,7-dicarboxamide …
Matched Iupac: … (1S,5S,7R)-N7-({[1,1'-biphenyl]-4-yl}methyl)-N3-hydroxy-6,8-dioxa-3-azabicyclo[3.2.1]octane-3,7-dicarboxamide …
N-{1-[(1-carbamoylcyclopropyl)methyl]piperidin-4-yl}-N-cyclopropyl-4-[(1S)-2,2,2-trifluoro-1-hydroxy-1-methylethyl]benzamide
Experimental
Matched Name: … N-{1-[(1-carbamoylcyclopropyl)methyl]piperidin-4-yl}-N-cyclopropyl-4-[(1S)-2,2,2-trifluoro-1-hydroxy- …
Matched Iupac: … N-{1-[(1-carbamoylcyclopropyl)methyl]piperidin-4-yl}-N-cyclopropyl-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan …
Matched Iupac: … N-{1-[(1-carbamoylcyclopropyl)methyl]piperidin-4-yl}-N-cyclopropyl-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan …
N-[1-(AMINOMETHYL)CYCLOPROPYL]-3-(MORPHOLIN-4-YLSULFONYL)-N~2~-[(1S)-2,2,2-TRIFLUORO-1-(4-FLUOROPHENYL)ETHYL]-L-ALANINAMIDE
Experimental
Matched Name: … N-[1-(AMINOMETHYL)CYCLOPROPYL]-3-(MORPHOLIN-4-YLSULFONYL)-N~2~-[(1S)-2,2,2-TRIFLUORO-1-(4-FLUOROPHENYL …
Matched Iupac: … (2R)-N-[1-(aminomethyl)cyclopropyl]-3-(morpholine-4-sulfonyl)-2-{[(1S)-2,2,2-trifluoro-1-(4-fluorophenyl …
Matched Iupac: … (2R)-N-[1-(aminomethyl)cyclopropyl]-3-(morpholine-4-sulfonyl)-2-{[(1S)-2,2,2-trifluoro-1-(4-fluorophenyl …
L-N(omega)-nitroarginine-(4R)-amino-L-proline amide
Experimental
Matched Name: … L-N(omega)-nitroarginine-(4R)-amino-L-proline amide …
Uridine-5'-Diphosphate-N-Acetylmuramoyl-L-Alanine-D-Glutamate
Experimental
Matched Name: … Uridine-5'-Diphosphate-N-Acetylmuramoyl-L-Alanine-D-Glutamate …
N-[2-(1-maleimidyl)ethyl]-7-diethylaminocoumarin-3-carboxamide
Experimental
Matched Name: … N-[2-(1-maleimidyl)ethyl]-7-diethylaminocoumarin-3-carboxamide …
Matched Iupac: … 7-(diethylamino)-N-[(1Z)-2-(2,5-dioxopyrrolidin-1-yl)ethenyl]-2-oxo-2H-chromene-3-carboxamide …
Matched Iupac: … 7-(diethylamino)-N-[(1Z)-2-(2,5-dioxopyrrolidin-1-yl)ethenyl]-2-oxo-2H-chromene-3-carboxamide …
1-[(2R)-2-aminobutanoyl]-N-(3-chlorobenzyl)-L-prolinamide
Experimental
Matched Name: … 1-[(2R)-2-aminobutanoyl]-N-(3-chlorobenzyl)-L-prolinamide …
Matched Iupac: … (2S)-1-[(2R)-2-aminobutanoyl]-N-[(3-chlorophenyl)methyl]pyrrolidine-2-carboxamide …
Matched Iupac: … (2S)-1-[(2R)-2-aminobutanoyl]-N-[(3-chlorophenyl)methyl]pyrrolidine-2-carboxamide …
1-[(2R)-2-aminobutanoyl]-N-(4-carbamimidoylbenzyl)-L-prolinamide
Experimental
Matched Name: … 1-[(2R)-2-aminobutanoyl]-N-(4-carbamimidoylbenzyl)-L-prolinamide …
Matched Iupac: … (2S)-1-[(2R)-2-aminobutanoyl]-N-[(4-carbamimidoylphenyl)methyl]pyrrolidine-2-carboxamide …
Matched Iupac: … (2S)-1-[(2R)-2-aminobutanoyl]-N-[(4-carbamimidoylphenyl)methyl]pyrrolidine-2-carboxamide …
(3S)-1-CYCLOHEXYL-5-OXO-N-PHENYLPYRROLIDINE-3-CARBOXAMIDE
Experimental
Matched Name: … (3S)-1-CYCLOHEXYL-5-OXO-N-PHENYLPYRROLIDINE-3-CARBOXAMIDE …
Matched Iupac: … (3S)-1-cyclohexyl-5-oxo-N-phenylpyrrolidine-3-carboxamide …
Matched Iupac: … (3S)-1-cyclohexyl-5-oxo-N-phenylpyrrolidine-3-carboxamide …
N-(4-phenoxyphenyl)-2-[(pyridin-4-ylmethyl)amino]nicotinamide
Experimental
Matched Name: … N-(4-phenoxyphenyl)-2-[(pyridin-4-ylmethyl)amino]nicotinamide …
Matched Iupac: … N-(4-phenoxyphenyl)-2-{[(pyridin-4-yl)methyl]amino}pyridine-3-carboxamide …
Matched Iupac: … N-(4-phenoxyphenyl)-2-{[(pyridin-4-yl)methyl]amino}pyridine-3-carboxamide …
5-CYANO-N-(2,5-DIMETHOXYBENZYL)-6-ETHOXYPYRIDINE-2-CARBOXAMIDE
Experimental
Matched Name: … 5-CYANO-N-(2,5-DIMETHOXYBENZYL)-6-ETHOXYPYRIDINE-2-CARBOXAMIDE …
Matched Iupac: … 5-cyano-N-[(2,5-dimethoxyphenyl)methyl]-6-ethoxypyridine-2-carboxamide …
Matched Iupac: … 5-cyano-N-[(2,5-dimethoxyphenyl)methyl]-6-ethoxypyridine-2-carboxamide …
Displaying drugs 1926 - 1950 of 2585 in total