Displaying drugs 176 - 200 of 6230 in total
Loxapine
An antipsychotic agent used in schizophrenia. [PubChem]
Approved
Matched Synonyms: … 2-Chloro-11-(4-methyl-1-piperazinyl)dibenz[b,f][1,4]oxazepine …
Matched Iupac: … 13-chloro-10-(4-methylpiperazin-1-yl)-2-oxa-9-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3,5,7,9,12,14 …
Matched Salts cas: … 27833-64-3 …
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Matched Products: … ADASUVE 9,1 MG İNHALASYON İÇİN KULLANIMA HAZIR TOZ, 1 ADET …
Matched Iupac: … 13-chloro-10-(4-methylpiperazin-1-yl)-2-oxa-9-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3,5,7,9,12,14 …
Matched Salts cas: … 27833-64-3 …
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Matched Products: … ADASUVE 9,1 MG İNHALASYON İÇİN KULLANIMA HAZIR TOZ, 1 ADET …
Amoxapine
Amoxapine, the N-demethylated derivative of the antipsychotic agent loxapine, is a dibenzoxazepine-derivative tricyclic antidepressant (TCA). TCAs are structurally similar to phenothiazines. They contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individuals, amoxapine does not affect mood or arousal, but may cause sedation....
Approved
Matched Synonyms: … 2-Chloro-11-(1-piperazinyl)dibenz(b,f)(1,4)oxazepine …
Matched Iupac: … 13-chloro-10-(piperazin-1-yl)-2-oxa-9-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3,5,7,9,12,14-heptaene …
Matched Description: … TCAs also block histamine H1 receptors, α1-adrenergic receptors and muscarinic ... Amoxapine, the N-demethylated derivative of the antipsychotic agent loxapine, is a dibenzoxazepine-derivative ... In depressed individuals, amoxapine exerts a positive effect on mood. …
Matched Categories: … Adrenergic alpha-1 Receptor Antagonists ... Heterocyclic Compounds, 3-Ring ... Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic Index …
Matched Iupac: … 13-chloro-10-(piperazin-1-yl)-2-oxa-9-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3,5,7,9,12,14-heptaene …
Matched Description: … TCAs also block histamine H1 receptors, α1-adrenergic receptors and muscarinic ... Amoxapine, the N-demethylated derivative of the antipsychotic agent loxapine, is a dibenzoxazepine-derivative ... In depressed individuals, amoxapine exerts a positive effect on mood. …
Matched Categories: … Adrenergic alpha-1 Receptor Antagonists ... Heterocyclic Compounds, 3-Ring ... Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic Index …
Nevirapine
A potent, non-nucleoside reverse transcriptase inhibitor (NNRTI) used in combination with nucleoside analogues for treatment of Human Immunodeficiency Virus Type 1 (HIV-1) infection and AIDS. Structurally, nevirapine belongs to the dipyridodiazepinone chemical class.
Approved
Matched Synonyms: … 11-cyclopropyl-5,11-dihydro-4-methyl-6H-dipyrido(3,2-b:2',3'-e)(1,4)diazepin-6-one …
Matched Iupac: … 2-cyclopropyl-7-methyl-2,4,9,15-tetraazatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3,5,7,12,14-hexaen-10- …
Matched Description: … analogues for treatment of Human Immunodeficiency Virus Type 1 (HIV-1) infection and AIDS. ... A potent, non-nucleoside reverse transcriptase inhibitor (NNRTI) used in combination with nucleoside …
Matched Salts cas: … 220988-26-1 …
Matched Mixtures name: … ZIMODINE N ® ... LAVUZID® N ... CIPLADUOVIR-N TABLETAS …
Matched Categories: … Human Immunodeficiency Virus 1 Non-Nucleoside Analog Reverse Transcriptase Inhibitor ... Heterocyclic Compounds, 1-Ring …
Matched Iupac: … 2-cyclopropyl-7-methyl-2,4,9,15-tetraazatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3,5,7,12,14-hexaen-10- …
Matched Description: … analogues for treatment of Human Immunodeficiency Virus Type 1 (HIV-1) infection and AIDS. ... A potent, non-nucleoside reverse transcriptase inhibitor (NNRTI) used in combination with nucleoside …
Matched Salts cas: … 220988-26-1 …
Matched Mixtures name: … ZIMODINE N ® ... LAVUZID® N ... CIPLADUOVIR-N TABLETAS …
Matched Categories: … Human Immunodeficiency Virus 1 Non-Nucleoside Analog Reverse Transcriptase Inhibitor ... Heterocyclic Compounds, 1-Ring …
Pirenzepine
An antimuscarinic agent that inhibits gastric secretion at lower doses than are required to affect gastrointestinal motility, salivary, central nervous system, cardiovascular, ocular, and urinary function. It promotes the healing of duodenal ulcers and due to its cytoprotective action is beneficial in the prevention of duodenal ulcer recurrence. It also...
Approved
Matched Synonyms: … 11-((4-Methyl-1-piperazinyl)acetyl)-5,11-dihydro-6H-pyrido(2,3-b)(1,4)benzodiazepin-6-one …
Matched Iupac: … 2-[2-(4-methylpiperazin-1-yl)acetyl]-2,4,9-triazatricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3(8),4,6,11,13 …
Matched Salts cas: … 29868-97-1 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … 2-[2-(4-methylpiperazin-1-yl)acetyl]-2,4,9-triazatricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3(8),4,6,11,13 …
Matched Salts cas: … 29868-97-1 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Brexucabtagene autoleucel
Mantle cell lymphoma is a heterogeneous sub-category of non-Hodgkin's lymphoma that can be classified as either an aggressive nodal or an indolent leukemic non-nodal variant. Despite the introduction of Bruton's tyrosine kinase (BTK) inhibitors such as ibrutinib and acalabrutinib, the prognosis for MCL patients remains poor and those that relapse...
Approved
Matched Description: … co-stimulatory domains of the chimeric antigen. ... [A216153, A216158]
More recently, chimeric antigen receptor (CAR) T cell therapies have been developed ... These therapies differ in manufacturing methodology, viral vector, chimeric antigen choice, and the internal …
Matched Categories: … Receptors, Antigen ... Receptors, Antigen, T-Cell …
Matched Categories: … Receptors, Antigen ... Receptors, Antigen, T-Cell …
Amikacin
Amikacin is a semi-synthetic aminoglycoside antibiotic that is derived from kanamycin A.[FDA label] Amikacin is synthesized by acylation with the l-(-)-γ-amino-α-hydroxybutyryl side chain at the C-1 amino group of the deoxystreptamine moiety of kanamycin A. Amikacin's unique property is that it exerts activity against more resistant gram-negative bacilli such as...
Approved
Investigational
Vet approved
Matched Synonyms: … 1-N-(L(−)-γ-amino-α-hydroxybutyryl)kanamycin A ... -D-GLUCOPYRANOSYL-(1->6))-N(SUP 3)-(4-AMINO-L-2-HYDROXYBUTYRYL)-2-DEOXY-L-STREPTAMINE ... -D-GLUCOPYRANOSYL-(1->4))-N(SUP 1)-(4-AMINO-2-HYDROXY-1-OXOBUTYL)-2-DEOXY-, (S)- …
Matched Iupac: … oxan-2-yl]oxy}-4-{[(2R,3R,4S,5S,6R)-6-(aminomethyl)-3,4,5-trihydroxyoxan-2-yl]oxy}-3-hydroxycyclohexyl ... (2S)-4-amino-N-[(1R,2S,3S,4R,5S)-5-amino-2-{[(2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl) ... ]-2-hydroxybutanamide …
Matched Description: … [F1949] In September 2018, a liposomal inhalation suspension of this drug was approved by the FDA for ... label] Amikacin is synthesized by acylation with the l-(-)-γ-amino-α-hydroxybutyryl side chain at the C-1 ... Amikacin is a semi-synthetic aminoglycoside antibiotic that is derived from kanamycin A. …
Matched Categories: … Drugs that are Mainly Renally Excreted with a Narrow Therapeutic Index …
Matched Products: … AMIKACINA 50 MG/ ML X 2 ML ... MIKACIL INYECTABLE500 MG X 2 ML. ... AMIKACINA B. BRAUN …
Matched Iupac: … oxan-2-yl]oxy}-4-{[(2R,3R,4S,5S,6R)-6-(aminomethyl)-3,4,5-trihydroxyoxan-2-yl]oxy}-3-hydroxycyclohexyl ... (2S)-4-amino-N-[(1R,2S,3S,4R,5S)-5-amino-2-{[(2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl) ... ]-2-hydroxybutanamide …
Matched Description: … [F1949] In September 2018, a liposomal inhalation suspension of this drug was approved by the FDA for ... label] Amikacin is synthesized by acylation with the l-(-)-γ-amino-α-hydroxybutyryl side chain at the C-1 ... Amikacin is a semi-synthetic aminoglycoside antibiotic that is derived from kanamycin A. …
Matched Categories: … Drugs that are Mainly Renally Excreted with a Narrow Therapeutic Index …
Matched Products: … AMIKACINA 50 MG/ ML X 2 ML ... MIKACIL INYECTABLE500 MG X 2 ML. ... AMIKACINA B. BRAUN …
Raloxifene
Raloxifene is a second generation selective estrogen receptor modulator (SERM) that mediates anti-estrogenic effects on breast and uterine tissues, and estrogenic effects on bone, lipid metabolism, and blood coagulation.[A4979,T28] Exhibiting tissue-specific effects distinct from estradiol, raloxifene is the first of the benzothiophene group of antiestrogens to be labelled a SERM....
Approved
Investigational
Matched Synonyms: … (2-(4-Hydroxyphenyl)-6-hydroxybenzo(b)thien-3-yl)(4-(2-(1-piperidinyl)ethoxy)phenyl)methanone …
Matched Iupac: … 2-(4-hydroxyphenyl)-3-{4-[2-(piperidin-1-yl)ethoxy]benzoyl}-1-benzothiophen-6-ol …
Matched Description: … Raloxifene is a second generation selective estrogen receptor modulator (SERM) that mediates anti-estrogenic ... from [estradiol], raloxifene is the first of the benzothiophene group of antiestrogens to be labelled a ... However, it has a negligible effect on altering the development and progression of breast cancer itself …
Matched Products: … ULOS-H …
Matched Iupac: … 2-(4-hydroxyphenyl)-3-{4-[2-(piperidin-1-yl)ethoxy]benzoyl}-1-benzothiophen-6-ol …
Matched Description: … Raloxifene is a second generation selective estrogen receptor modulator (SERM) that mediates anti-estrogenic ... from [estradiol], raloxifene is the first of the benzothiophene group of antiestrogens to be labelled a ... However, it has a negligible effect on altering the development and progression of breast cancer itself …
Matched Products: … ULOS-H …
Finafloxacin
Finafloxacin is a fluoroquinolone antibiotic indicated in the treatment of acute otitis externa (swimmer's ear) caused by the bacteria Pseudomonas aeruginosa and Staphylococcus aureus. Finafloxacin is marketed by Novartis under the brand Xtoro™, and was approved by the FDA in December 2014.
Approved
Investigational
Matched Synonyms: … 8-Cyano-1-cyclopropyl-6-fluoro-7-[(4aS,7aS)-hexahydropyrrolo[3,4-b][1,4]oxazin-6(2H)-yl]-4-oxo-1,4-dihydro ... -3-quinolinecarboxylic acid …
Matched Iupac: … 7-[(4aS,7aS)-octahydropyrrolo[3,4-b]morpholin-6-yl]-8-cyano-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline ... -3-carboxylic acid …
Matched Description: … Finafloxacin is a fluoroquinolone antibiotic indicated in the treatment of acute otitis externa (swimmer's …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … 7-[(4aS,7aS)-octahydropyrrolo[3,4-b]morpholin-6-yl]-8-cyano-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline ... -3-carboxylic acid …
Matched Description: … Finafloxacin is a fluoroquinolone antibiotic indicated in the treatment of acute otitis externa (swimmer's …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Paromomycin
An oligosaccharide antibiotic produced by various streptomyces. [PubChem]
Approved
Investigational
Matched Synonyms: … ]oxy}-3-hydroxycyclohexyl 2-amino-2-deoxy-alpha-D-glucopyranoside ... Monomycin A ... (1R,2R,3S,4R,6S)-4,6-diamino-2-{[3-O-(2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl)-beta-D-ribofuranosyl …
Matched Iupac: … -6-(aminomethyl)-4,5-dihydroxyoxan-2-yl]oxy}-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]oxy}-3-hydroxycyclohexyl ... (2R,3S,4R,5R,6S)-5-amino-6-{[(1R,2R,3S,4R,6S)-4,6-diamino-2-{[(2S,3R,4S,5R)-4-{[(2R,3R,4R,5S,6S)-3-amino ... ]oxy}-2-(hydroxymethyl)oxane-3,4-diol …
Matched Products: … GABROSIDIN 0.5 G ENJEKTABL FLAKON, 1 ADET …
Matched Iupac: … -6-(aminomethyl)-4,5-dihydroxyoxan-2-yl]oxy}-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]oxy}-3-hydroxycyclohexyl ... (2R,3S,4R,5R,6S)-5-amino-6-{[(1R,2R,3S,4R,6S)-4,6-diamino-2-{[(2S,3R,4S,5R)-4-{[(2R,3R,4R,5S,6S)-3-amino ... ]oxy}-2-(hydroxymethyl)oxane-3,4-diol …
Matched Products: … GABROSIDIN 0.5 G ENJEKTABL FLAKON, 1 ADET …
Adefovir dipivoxil
Adefovir dipivoxil, previously called bis-POM PMEA, with trade names Preveon and Hepsera, is an orally-administered acyclic nucleotide analog reverse transcriptase inhibitor (ntRTI) used for treatment of hepatitis B. It is ineffective against HIV-1. Adefovir dipivoxil is the diester prodrug of adefovir.
Approved
Investigational
Matched International brands: … A Di Xian ... A Gan Ding …
Matched Iupac: … [({[2-(6-amino-9H-purin-9-yl)ethoxy]methyl}({[(2,2-dimethylpropanoyl)oxy]methoxy})phosphoryl)oxy]methyl …
Matched Description: … It is ineffective against HIV-1. Adefovir dipivoxil is the diester prodrug of adefovir. ... orally-administered acyclic nucleotide analog reverse transcriptase inhibitor (ntRTI) used for treatment of hepatitis B. …
Matched Categories: … Hepatitis B Virus Nucleoside Analog Reverse Transcriptase Inhibitor ... Heterocyclic Compounds, 2-Ring …
Matched Iupac: … [({[2-(6-amino-9H-purin-9-yl)ethoxy]methyl}({[(2,2-dimethylpropanoyl)oxy]methoxy})phosphoryl)oxy]methyl …
Matched Description: … It is ineffective against HIV-1. Adefovir dipivoxil is the diester prodrug of adefovir. ... orally-administered acyclic nucleotide analog reverse transcriptase inhibitor (ntRTI) used for treatment of hepatitis B. …
Matched Categories: … Hepatitis B Virus Nucleoside Analog Reverse Transcriptase Inhibitor ... Heterocyclic Compounds, 2-Ring …
Bulevirtide
Hepatitis D is considered the most severe type of viral hepatitis and leads to the rapid development of cirrhosis, severe decompensation of liver function, and an increased risk of mortality.[A226340,L30235] Until recently, there have been extremely limited treatments available for Hepatitis D infection. Bulevirtide, also known as Hepcludex, is a...
Approved
Investigational
Matched International brands: … Myrcludex B …
Matched Description: … [A226305] Bulevirtide, also known as Hepcludex, is a first-in-class entry inhibitor for the treatment …
Matched Description: … [A226305] Bulevirtide, also known as Hepcludex, is a first-in-class entry inhibitor for the treatment …
Niacin
Niacin is a B vitamin used to treat vitamin deficiencies as well as hyperlipidemia, dyslipidemia, hypertriglyceridemia, and to reduce the risk of myocardial infarctions.[L7550,L7553,L7556,L7559,L7562,L7565]
Approved
Investigational
Nutraceutical
Matched Synonyms: … 3-carboxypyridine ... 3-Pyridinecarboxylic acid ... 3-Pyridylcarboxylic acid …
Matched Iupac: … pyridine-3-carboxylic acid …
Matched Description: … Niacin is a B vitamin used to treat vitamin deficiencies as well as hyperlipidemia, dyslipidemia, hypertriglyceridemia …
Matched Mixtures name: … BION 3 FILM COATED TABLET ... Master Key Formula 3 Tab ... Vitamin & Mineral Formula 1 Dietary Supplement …
Matched Categories: … Vitamin B Complex ... Heterocyclic Compounds, 1-Ring …
Matched Products: … B-3 500mg Continuous Released …
Matched Iupac: … pyridine-3-carboxylic acid …
Matched Description: … Niacin is a B vitamin used to treat vitamin deficiencies as well as hyperlipidemia, dyslipidemia, hypertriglyceridemia …
Matched Mixtures name: … BION 3 FILM COATED TABLET ... Master Key Formula 3 Tab ... Vitamin & Mineral Formula 1 Dietary Supplement …
Matched Categories: … Vitamin B Complex ... Heterocyclic Compounds, 1-Ring …
Matched Products: … B-3 500mg Continuous Released …
Clobazam
Clobazam belongs to the 1,5-benzodiazepine class of drugs and is marketed under different names, Onfi, Frisium, Urbanyl, and others. . Clobazam was first synthesized in 1966 and first published in 1969, following the incidental synthesis and discovery of the first benzodiazepine chlordiazepoxide in the 1950s. Unlike older 1,4-benzodiazepines, clobazam has...
Approved
Illicit
Matched Synonyms: … 7-Chloro-1-methyl-5-phenyl-1,5-dihydro-benzo[b][1,4]diazepine-2,4-dione ... 1-phenyl-5-methyl-8-chloro-1,2,4,5-tetrahydro-2,4-dioxo-3H-1,5-benzodiazepine …
Matched Iupac: … 7-chloro-1-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-1,5-benzodiazepine-2,4-dione …
Matched Description: … the GABAA receptor, which mediates anxiolytic effects, than the α1 subunit, which ... [A256963,A256868] This is likely because of clobazam's higher affinity to the α2 subunit of ... [A256868] Additionally, clobazam is believed to be a partial agonist to the GABAA receptor …
Matched Categories: … GABA-A Receptor Agonists ... Heterocyclic Compounds, 2-Ring …
Matched Products: … Clobazam Essential Pharmaceuticals 1 mg/ml Suspension zum Einnehmen …
Matched Iupac: … 7-chloro-1-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-1,5-benzodiazepine-2,4-dione …
Matched Description: … the GABAA receptor, which mediates anxiolytic effects, than the α1 subunit, which ... [A256963,A256868] This is likely because of clobazam's higher affinity to the α2 subunit of ... [A256868] Additionally, clobazam is believed to be a partial agonist to the GABAA receptor …
Matched Categories: … GABA-A Receptor Agonists ... Heterocyclic Compounds, 2-Ring …
Matched Products: … Clobazam Essential Pharmaceuticals 1 mg/ml Suspension zum Einnehmen …
Ginkgo biloba
Ginkgo biloba extract contains a group of terpene lactones (notably, ginkgolides and diterpenes) and ginkgo flavone glycosides (notably, ginkgetin, bilobetin, and sciadopitysin) that have antioxidant and vasoactive properties. Most of the studies that investigate the effect of ginkgo biloba use the standardized extract of Ginkgo biloba (EGb) 761 (EGb761), which...
Approved
Investigational
Nutraceutical
Matched Description: … Lactones include ginkgolide A, ginkgolide B, ginkgolide C, bilobalide, and ginkgotoxin, a lactone that ... _Ginkgo biloba_ extract contains a group of terpene lactones (notably, ginkgolides and diterpenes) and ... biloba_ use the standardized extract of _Ginkgo biloba_ (EGb) 761 (EGb761), which was developed by a …
Matched Mixtures name: … GINKOREM 5/80 MG EFERVESAN TABLET, 14 ADET …
Matched Categories: … Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates …
Matched Products: … TEBONIN 120MG B OHRGERAEU ... EXTRACTO DE GINKO BILOBA AL 24 % EQUIVALENTE A 9.6 MG DE GLICOSIDOS FLAVONOIDES. …
Matched Mixtures name: … GINKOREM 5/80 MG EFERVESAN TABLET, 14 ADET …
Matched Categories: … Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates …
Matched Products: … TEBONIN 120MG B OHRGERAEU ... EXTRACTO DE GINKO BILOBA AL 24 % EQUIVALENTE A 9.6 MG DE GLICOSIDOS FLAVONOIDES. …
Zilucoplan
Zilucoplan is a 15 amino-acid, synthetic macrocyclic peptide. It is a complement inhibitor that works to prevent the activation of C5, which is a complement protein involved in the innate immune system to initiate inflammatory responses. On October 17, 2023, zilucoplan gained its first FDA approval for the treatment of...
Approved
Matched Synonyms: … .-(2-(((4S)-4-CARBOXY-1-OXO-4-(1-OXOHEXADECYL)BUTYL)AMINO)ETHYL)-.OMEGA. ... -HYDROXY-, 15-ETHER WITH N-ACETYL-L-LYSYL-L-VALYL-L-.ALPHA. ... -ASPARTYL-3-METHYL-L-VALYL-L-TYROSYL-3-(1H-PYRROLO(2,3-B)PYRIDIN-3-YL)-L-ALANYL-L-.ALPHA. …
Matched Iupac: … 2-yl)-1,4,7,10,13,17-hexaazacyclotricosan-14-yl]-N-methylformamido}-3-carboxypropanamido]-3,3-dimethylbutanamido ... ]-3-(4-hydroxyphenyl)propanamido]-3-{1H-pyrrolo[2,3-b]pyridin-3-yl}propanamido]-4-carboxybutanamido]- ... (2S)-2-[(2S)-2-{[(2S)-1-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-{1-[(2S,5S,8S,11S,14S,22S)-11 ... 3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-2-cyclohexylacetamido]-6-{1-[(4S)-4-carboxy-4 ... -benzyl-8-(3-carbamimidamidopropyl)-5-(2-carboxyethyl)-22-acetamido-3,6,9,12,16,23-hexaoxo-2-(propan- …
Matched Description: … Zilucoplan is a 15 amino-acid, synthetic macrocyclic peptide. ... It is a complement inhibitor that works to prevent the activation of C5, which is a complement protein …
Matched Iupac: … 2-yl)-1,4,7,10,13,17-hexaazacyclotricosan-14-yl]-N-methylformamido}-3-carboxypropanamido]-3,3-dimethylbutanamido ... ]-3-(4-hydroxyphenyl)propanamido]-3-{1H-pyrrolo[2,3-b]pyridin-3-yl}propanamido]-4-carboxybutanamido]- ... (2S)-2-[(2S)-2-{[(2S)-1-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-{1-[(2S,5S,8S,11S,14S,22S)-11 ... 3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-2-cyclohexylacetamido]-6-{1-[(4S)-4-carboxy-4 ... -benzyl-8-(3-carbamimidamidopropyl)-5-(2-carboxyethyl)-22-acetamido-3,6,9,12,16,23-hexaoxo-2-(propan- …
Matched Description: … Zilucoplan is a 15 amino-acid, synthetic macrocyclic peptide. ... It is a complement inhibitor that works to prevent the activation of C5, which is a complement protein …
Cinoxacin
Synthetic antimicrobial related to oxolinic acid and nalidixic acid and used in urinary tract infections.
Approved
Investigational
Withdrawn
Matched Synonyms: … 1-ethyl-6,7-methylenedioxy-4(1H)-oxocinnoline-3-carboxylic acid ... 5-Ethyl-8-oxo-5,8-dihydro-1,3-dioxa-5,6-diaza-cyclopenta[b]naphthalene-7-carboxylic acid …
Matched Iupac: … 1-ethyl-4-oxo-1H,4H,7H-[1,3]dioxolo[4,5-g]cinnoline-3-carboxylic acid …
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Matched Iupac: … 1-ethyl-4-oxo-1H,4H,7H-[1,3]dioxolo[4,5-g]cinnoline-3-carboxylic acid …
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Benfotiamine
Benfotiamine has been investigated for the treatment and prevention of Diabetic Nephropathy and Diabetes Mellitus, Type 2.
Approved
Experimental
Matched Iupac: … {[(3Z)-4-{N-[(4-amino-2-methylpyrimidin-5-yl)methyl]formamido}-3-[(Z)-benzoylsulfanyl]pent-3-en-1-yl] …
Matched Description: … been investigated for the treatment and prevention of Diabetic Nephropathy and Diabetes Mellitus, Type 2. …
Matched Categories: … Vitamin B Complex ... Heterocyclic Compounds, 1-Ring ... Compounds used in a research, industrial, or household setting …
Matched Products: … NEVRALON B 300 MG FİLM KAPLI TABLET, 30 TABLET ... NEVRALON B 150 MG FİLM KAPLI TABLET, 30 TABLET …
Matched Description: … been investigated for the treatment and prevention of Diabetic Nephropathy and Diabetes Mellitus, Type 2. …
Matched Categories: … Vitamin B Complex ... Heterocyclic Compounds, 1-Ring ... Compounds used in a research, industrial, or household setting …
Matched Products: … NEVRALON B 300 MG FİLM KAPLI TABLET, 30 TABLET ... NEVRALON B 150 MG FİLM KAPLI TABLET, 30 TABLET …
Antithrombin III human
A plasma alpha 2 glycoprotein that accounts for the major antithrombin activity of normal plasma and also inhibits several other enzymes. It is a member of the serpin superfamily.
Approved
Matched Synonyms: … Heparin cofactor B …
Matched Description: … A plasma alpha 2 glycoprotein that accounts for the major antithrombin activity of normal plasma and ... It is a member of the serpin superfamily. …
Matched Description: … A plasma alpha 2 glycoprotein that accounts for the major antithrombin activity of normal plasma and ... It is a member of the serpin superfamily. …
Ensulizole
Ensulizole, also known as 2-phenylbenzimidazole-5-sulfonic acid, is a water-soluble sunscreen agent that absorbs strongly at UV-B wavelengths. It is commonly found in cosmetic products and sunscreen formulas in combination with other UV filter compounds due to its minimal protection against UV-A wavelengths. Due to its water solubility, ensulizole is commonly...
Approved
Matched Iupac: … 2-phenyl-1H-1,3-benzodiazole-6-sulfonic acid …
Matched Description: … Ensulizole, also known as 2-phenylbenzimidazole-5-sulfonic acid, is a water-soluble sunscreen agent that ... or UV-B exposure [A27151]. ... absorbs strongly at UV-B wavelengths. …
Matched Mixtures name: … Aqua Fusion SPF 15 Peau Normale A Seche ... Happyderm SPF 15 Peaux Normales A Seches ... Happyderm SPF 15 Peaux Normales A Grasses …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … Covergirl Outlast All Day Stay Fabulous 3-IN-1 Foundation ... Tattoo Color Guard SPF 15 ... Sungirl SPF 3 …
Matched Description: … Ensulizole, also known as 2-phenylbenzimidazole-5-sulfonic acid, is a water-soluble sunscreen agent that ... or UV-B exposure [A27151]. ... absorbs strongly at UV-B wavelengths. …
Matched Mixtures name: … Aqua Fusion SPF 15 Peau Normale A Seche ... Happyderm SPF 15 Peaux Normales A Seches ... Happyderm SPF 15 Peaux Normales A Grasses …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … Covergirl Outlast All Day Stay Fabulous 3-IN-1 Foundation ... Tattoo Color Guard SPF 15 ... Sungirl SPF 3 …
Doxorubicin
Doxorubicin is a cytotoxic anthracycline antibiotic isolated from cultures of Streptomyces peucetius var. caesius along side with daunorubicin, another cytotoxic agent, in 1970.[A1575,A257709,A257614] Although they both have aglyconic and sugar moieties, doxorubicin's side chain terminates with a primary alcohol group compared to the methyl group of daunorubicin. Although its detailed...
Approved
Investigational
Matched Synonyms: … (1S,3S)-3-glycoloyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino ... 14-hydroxydaunomycin ... 14-hydroxydaunorubicine …
Matched Iupac: … )-1-methoxy-5,7,8,9,10,12-hexahydrotetracene-5,12-dione ... (8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy}-6,8,11-trihydroxy-8-(2-hydroxyacetyl …
Matched Description: … Doxorubicin is a cytotoxic anthracycline antibiotic isolated from cultures of Streptomyces peucetius ... A257614] Although they both have aglyconic and sugar moieties, doxorubicin's side chain terminates with a ... A257614] Thanks to its efficacy and broad effect, doxorubicin was approved by the FDA in 1974 to treat a …
Matched Categories: … BSEP/ABCB11 Substrates with a Narrow Therapeutic Index ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Matched Products: … DOXORUBICINA 50 MG / 15 ML ... DOXORUBICIN INYECTABLE X 100 MG ... CAELYX 2 MG/ML KONSANTRE İNFUZYON ÇÖZELTİSİ, 1 ADET …
Matched Iupac: … )-1-methoxy-5,7,8,9,10,12-hexahydrotetracene-5,12-dione ... (8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy}-6,8,11-trihydroxy-8-(2-hydroxyacetyl …
Matched Description: … Doxorubicin is a cytotoxic anthracycline antibiotic isolated from cultures of Streptomyces peucetius ... A257614] Although they both have aglyconic and sugar moieties, doxorubicin's side chain terminates with a ... A257614] Thanks to its efficacy and broad effect, doxorubicin was approved by the FDA in 1974 to treat a …
Matched Categories: … BSEP/ABCB11 Substrates with a Narrow Therapeutic Index ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Matched Products: … DOXORUBICINA 50 MG / 15 ML ... DOXORUBICIN INYECTABLE X 100 MG ... CAELYX 2 MG/ML KONSANTRE İNFUZYON ÇÖZELTİSİ, 1 ADET …
Rezafungin
Rezafungin is an echinocandin antifungal drug.[A258393,L45633] Unlike other echinocandins such as caspofungin and micafungin, rezafungin has long‐acting pharmacokinetics and a high stability that allows for it to have long dosing intervals maintaining high plasma exposure. Rezafungin has a half-life higher than 130 hours and can be administered once a week...
Approved
Investigational
Matched Synonyms: … Echinocandin B, 1-((4R,5R)-4-hydroxy-N2-((4''-(pentyloxy)(1,1':4',1''-terphenyl)-4-yl)carbonyl)-5-(2- …
Matched Iupac: … (2-{[(3S,4E,6S,7E,9S,11R,15S,16E,18S,20R,21R,22E,24S,25S,26S)-6-[(1S,2S)-1,2-dihydroxy-2-(4-hydroxyphenyl ... heptahydroxy-18-[(Z)-[hydroxy({4-[4'-(pentyloxy)-[1,1'-biphenyl]-4-yl]phenyl})methylidene]amino]-3,15-bis[(1R)-1- …
Matched Description: … Rezafungin has a half-life higher than 130 hours and can be administered once a week instead of daily ... echinocandins such as [caspofungin] and [micafungin], rezafungin has long‐acting pharmacokinetics and a …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … (2-{[(3S,4E,6S,7E,9S,11R,15S,16E,18S,20R,21R,22E,24S,25S,26S)-6-[(1S,2S)-1,2-dihydroxy-2-(4-hydroxyphenyl ... heptahydroxy-18-[(Z)-[hydroxy({4-[4'-(pentyloxy)-[1,1'-biphenyl]-4-yl]phenyl})methylidene]amino]-3,15-bis[(1R)-1- …
Matched Description: … Rezafungin has a half-life higher than 130 hours and can be administered once a week instead of daily ... echinocandins such as [caspofungin] and [micafungin], rezafungin has long‐acting pharmacokinetics and a …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Benzylpenicillin
Benzylpenicillin (Penicillin G) is narrow spectrum antibiotic used to treat infections caused by susceptible bacteria. It is a natural penicillin antibiotic that is administered intravenously or intramuscularly due to poor oral absorption. Penicillin G may also be used in some cases as prophylaxis against susceptible organisms.
Natural penicillins are considered...
Approved
Vet approved
Matched Synonyms: … (2S,5R,6R)-3,3-dimethyl-7-oxo-6-(phenylacetamido)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid ... 6-(2-phenylacetamido)penicillanic acid …
Matched Iupac: … (2S,5R,6R)-3,3-dimethyl-7-oxo-6-(2-phenylacetamido)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid …
Matched Description: … It is a natural penicillin antibiotic that is administered intravenously or intramuscularly due to poor ... Aminoglycosides may be added for synergy against group B streptococcus (*S. agalactiae*), *S. viridans ... infections caused by susceptible gram positive aerobic organisms, such as *Streptococcus pneumoniae*, groups A, …
Matched Salts cas: … 41372-02-5 …
Matched Mixtures name: … Bicillin A-P Injection Pws ... Bicillin A-P Injection Pws ... SENTINA 6:3:3 ENJEKTABL TOZ İÇEREN FLAKON IM, 1ADET …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
Matched Products: … Bicillin L-A ... Bicillin L-A Injection Sus 1200000iu/2ml ... PENICILINA G SODICA 5000000UI POLVO ESTERIL PARA RECONSTITUIR A SOLUCION INYECTABLE …
Matched Iupac: … (2S,5R,6R)-3,3-dimethyl-7-oxo-6-(2-phenylacetamido)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid …
Matched Description: … It is a natural penicillin antibiotic that is administered intravenously or intramuscularly due to poor ... Aminoglycosides may be added for synergy against group B streptococcus (*S. agalactiae*), *S. viridans ... infections caused by susceptible gram positive aerobic organisms, such as *Streptococcus pneumoniae*, groups A, …
Matched Salts cas: … 41372-02-5 …
Matched Mixtures name: … Bicillin A-P Injection Pws ... Bicillin A-P Injection Pws ... SENTINA 6:3:3 ENJEKTABL TOZ İÇEREN FLAKON IM, 1ADET …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
Matched Products: … Bicillin L-A ... Bicillin L-A Injection Sus 1200000iu/2ml ... PENICILINA G SODICA 5000000UI POLVO ESTERIL PARA RECONSTITUIR A SOLUCION INYECTABLE …
Padimate O
Padimate O is an active sunscreen agent in cosmetics and over-the-counter sunscreen drug products in concentrations up to 8%, as regulated by the FDA . It is a structurally-related compound to DB02362 that absorbs UV-B rays to prevent photodamage. It penetrates human skin, and is shown to induce non-ligatable strand...
Approved
Matched Iupac: … 2-ethylhexyl 4-(dimethylamino)benzoate …
Matched Description: … It is a structurally-related compound to [DB02362] that absorbs UV-B rays to prevent photodamage. …
Matched Mixtures name: … Dermatone SPF 23 Lips N Face Protector ... Savex Sunblock 15 Ont SPF 15 ... Lip Healer SPF 15 …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … Ultimate Moist SPF 15 ... Hand and Body Lotion SPF 15 …
Matched Description: … It is a structurally-related compound to [DB02362] that absorbs UV-B rays to prevent photodamage. …
Matched Mixtures name: … Dermatone SPF 23 Lips N Face Protector ... Savex Sunblock 15 Ont SPF 15 ... Lip Healer SPF 15 …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … Ultimate Moist SPF 15 ... Hand and Body Lotion SPF 15 …
Bendamustine
Bendamustine is a nitrogen mustard drug which has been used in the treatment of chronic lymphocytic leukemia (CLL) and indolent B-cell non-Hodgkin lymphoma (NHL). Bendamustine is a bifunctional mechlorethamine derivative capable of forming electrophilic alkyl groups that covalently bond to other molecules. Through this function as an alkylating agent, bendamustine...
Approved
Investigational
Matched Iupac: … 4-{5-[bis(2-chloroethyl)amino]-1-methyl-1H-1,3-benzodiazol-2-yl}butanoic acid …
Matched Description: … (CLL) and indolent B-cell non-Hodgkin lymphoma (NHL). ... Bendamustine is a nitrogen mustard drug which has been used in the treatment of chronic lymphocytic leukemia ... Bendamustine is a bifunctional mechlorethamine derivative capable of forming electrophilic alkyl groups …
Matched Salts cas: … 1374784-02-7 …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index …
Matched Products: … GENSTINA® POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION INYECTABLE ... INFÜZYON IÇIN LIYOFILIZE TOZ IÇEREN FLAKON ,1 ADET ... INFÜZYON IÇIN LIYOFILIZE TOZ IÇEREN FLAKON ,1 ADET …
Matched Description: … (CLL) and indolent B-cell non-Hodgkin lymphoma (NHL). ... Bendamustine is a nitrogen mustard drug which has been used in the treatment of chronic lymphocytic leukemia ... Bendamustine is a bifunctional mechlorethamine derivative capable of forming electrophilic alkyl groups …
Matched Salts cas: … 1374784-02-7 …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index …
Matched Products: … GENSTINA® POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION INYECTABLE ... INFÜZYON IÇIN LIYOFILIZE TOZ IÇEREN FLAKON ,1 ADET ... INFÜZYON IÇIN LIYOFILIZE TOZ IÇEREN FLAKON ,1 ADET …
Zinc
A metallic element of atomic number 30 and atomic weight 65.38. It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell division. Zinc deficiency is associated with anemia, short stature, hypogonadism, impaired wound...
Approved
Investigational
Matched Description: … polymorphism of the common polymorphism in zinc transporter _SLC30A8/ZnT8_ may increase susceptibility to type 2 ... A metallic element of atomic number 30 and atomic weight 65.38. ... It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an …
Matched Mixtures name: … Acti-cal/mag 2:1 + Zinc and D Caplet ... Chelated Cal-mag(2:1)with Zn Vit.c and D ... ADDAMEL N …
Matched Products: … Port A Mins Super Zinc 15 ... Port A Mins Super Zinc 30 ... ZINCLOMIN 15 MG/5 ML 100 ML SURUP …
Matched Mixtures name: … Acti-cal/mag 2:1 + Zinc and D Caplet ... Chelated Cal-mag(2:1)with Zn Vit.c and D ... ADDAMEL N …
Matched Products: … Port A Mins Super Zinc 15 ... Port A Mins Super Zinc 30 ... ZINCLOMIN 15 MG/5 ML 100 ML SURUP …
Displaying drugs 176 - 200 of 6230 in total