Advanced Filter

Filter by Group

Filter by Market Availability

Clear
Displaying drugs 1976 - 2000 of 15247 in total

Dexmethylphenidate

Dexmethylphenidate is the dextrorotary form of methylphenidate introduced in 2002 . It is a norepinephrine-dopamine reuptake inhibitor (NDRI) and thus a psychostimulant . It is used for treatment of Attention Deficit Hyperactivity Disorder (ADHD)[Label,A177181]. The d-isomer is thought to have greater effect with fewer side effects than the l-isomer or...
Approved
Investigational
Matched Description: … It is a norepinephrine-dopamine reuptake inhibitor (NDRI) and thus a psychostimulant[A177193]. …
Matched Categories: … Methylphenidate and isomer ... dexmethylphenidate and serdexmethylphenidate ... Psychostimulants, Agents Used for ADHD and Nootropics …

Dantrolene

Chemically, dantrolene is a hydantoin derivative, but does not exhibit antiepileptic activity like other hydantoin derivates such as phenytoin.
Approved
Investigational
Matched Categories: … Dantrolene and Derivatives …

Medrysone

Medrysone is a corticosteroid used in ophthalmology.
Approved
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …

Ecallantide

Ecallantide is a potent and selective human plasma kallikrein inhibitor that is indicated for the symptomatic treatment of hereditary angioedema. Ecallantide is a recombinant 60-amino-acid protein produced in Pichia pastoris yeast cells that contains three intramolecular disulfide bonds [FDA Label]. It was discovered by phage display technology . It shares...
Approved
Investigational
Matched Description: … The amino acid sequence of two compounds differ by seven amino acids [L1458]. ... Ecallantide is a recombinant 60-amino-acid protein produced in _Pichia pastoris_ yeast cells that contains ... activity of kallikrein and excessive bradykinin production [FDA Label]. …
Matched Categories: … Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins …

Mecasermin

Mecasermin contains recombinant-DNA-engineered human insulin-like growth factor-1 (rhIGF-1)[FDA Label]. IGF-1 consists of 70 amino acids in a single chain with three intramolecular disulfide bridges and a molecular weight of 7649 daltons. The amino acid sequence of the product is identical to that of endogenous human IGF-1. The rhIGF-1 protein is...
Approved
Investigational
Matched Description: … The amino acid sequence of the product is identical to that of endogenous human IGF-1. ... IGF-1 consists of 70 amino acids in a single chain with three intramolecular disulfide bridges and a …
Matched Categories: … Pituitary and Hypothalamic Hormones and Analogues ... Sex Hormones and Insulins ... Amino Acids, Peptides, and Proteins ... Somatropin and Somatropin Agonists ... Anterior Pituitary Lobe Hormones and Analogues …

Teduglutide

Teduglutide is a glucagon-like peptide-2 (GLP-2) analogue. It is made up of 33 amino acids and is manufactured using a strain of Escherichia coli modified by recombinant DNA technology. Teduglutide differs from GLP-2 by one amino acid (alanine is substituted by glycine). The significance of this substitution is that teduglutide...
Approved
Matched Description: … Teduglutide differs from GLP-2 by one amino acid (alanine is substituted by glycine). ... It is made up of 33 amino acids and is manufactured using a strain of Escherichia coli modified by recombinant …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... Various Alimentary Tract and Metabolism Products ... Hormones, Hormone Substitutes, and Hormone Antagonists …

Lumefantrine

Lumefantrine is an antimalarial agent used to treat acute uncomplicated malaria. It is administered in combination with artemether for improved efficacy. This combination therapy exerts its effects against the erythrocytic stages of Plasmodium spp. and may be used to treat infections caused by P. falciparum and unidentified Plasmodium species, including...
Approved
Matched Description: … and may be used to treat infections caused by P. falciparum and unidentified Plasmodium …
Matched Categories: … artemether and lumefantrine ... Antiparasitic Products, Insecticides and Repellents …

Desoximetasone

A topical anti-inflammatory glucocorticoid used in dermatoses, skin allergies, psoriasis, etc.
Approved
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …

Delamanid

Delamanid is an anti-tuberculosis agent derived from the nitro-dihydro-imidazooxazole class of compounds that inhibits mycolic acid synthesis of bacterial cell wall . It is used in the treatment of multidrug-resistant and extensively drug-resistant tuberculosis (TB) in a combination regimen. Emergence of multidrug-resistant and extensively drug-resistant tuberculosis creates clinical challenges for...
Approved
Investigational
Matched Description: … anti-tuberculosis agent derived from the nitro-dihydro-imidazooxazole class of compounds that inhibits mycolic acid ... response to standardized antituberculosis treatments as [DB00951] and [DB01045]. ... It is used in the treatment of multidrug-resistant and extensively drug-resistant tuberculosis (TB) in …

Selenomethionine

Selenomethionine is a naturally occuring amino acid in some plant materials such as cereal grains, soybeans and enriched yeast but it cannot be synthesized from animals or humans. It can be produced from post-structural modifications. In vivo, selenomethionine plays an essential role in acting as an antioxidant, where it depletes...
Approved
Investigational
Matched Iupac: … (2S)-2-amino-4-(methylselanyl)butanoic acid …
Matched Description: … Selenomethionine is a naturally occuring amino acid in some plant materials such as cereal grains, soybeans ... and enriched yeast but it cannot be synthesized from animals or humans. ... aids in the formation and recycling of glutathione, another important antioxidant. …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Afamelanotide

Afamelanotide is a first-in-class, synthetic, 13-amino acid peptide analogue of the endogenous alpha melanocyte-stimulating hormone (α-MSH). It differs structurally from its endogenous counterpart by only two amino acids - these structural differences improve biological efficacy by imparting a greater affinity for its target and a longer biological half-life.[A187202,A187205] Afamelanotide is...
Approved
Investigational
Matched Iupac: … acetamido-3-hydroxypropanamido]-3-(4-hydroxyphenyl)propanamido]-3-hydroxypropanamido]hexanamido]butanoic acid …
Matched Description: … Afamelanotide is a first-in-class, synthetic, 13-amino acid peptide analogue of the endogenous alpha ... these structural differences improve biological efficacy by imparting a greater affinity for its target and ... relatively recent approval, afamelanotide has been available for use as an orphan drug in both the US and …
Matched Categories: … Indicators and Reagents ... Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …

Dosulepin

Dosulepin (INN, BAN) formerly known as dothiepin (USAN), is a tricyclic antidepressant with anxiolytic properties that is used in several European and South Asian countries, as well as Australia, South Africa, and New Zealand. It is not FDA-approved due to low therpeutic index and significant toxicity in overdose. Dosulepin inhibits...
Approved
Matched Description: … South Asian countries, as well as Australia, South Africa, and New Zealand. ... anticholinergic, antihistamine and central sedative properties [L882]. ... It is not FDA-approved due to low therpeutic index and significant toxicity in overdose. …

Festuca pratensis pollen

Festuca pratensis pollen is the pollen of the Festuca pratensis plant. Festuca pratensis pollen is mainly used in allergenic testing.
Approved
Matched Mixtures name: … Mixture of Twenty-Two Standardized and Non-Standardized Grasses …

Rimantadine

An RNA synthesis inhibitor that is used as an antiviral agent in the prophylaxis and treatment of influenza.
Approved
Investigational
Matched Description: … An RNA synthesis inhibitor that is used as an antiviral agent in the prophylaxis and treatment of influenza …
Matched Categories: … Nucleic Acid Synthesis Inhibitors …

Prochlorperazine

Prochlorperazine, also known as compazine, is a piperazine phenothiazine and first-generation antipsychotic drug that is used for the treatment of severe nausea and vomiting, as well as short-term management of psychotic disorders such as generalized non-psychotic anxiety and schizophrenia.[label] It mainly works by depressing the chemoreceptor trigger zone and blocking...
Approved
Vet approved
Matched Description: … of psychotic disorders such as generalized non-psychotic anxiety and schizophrenia. ... It was shown to also block histaminergic, cholinergic and noradrenergic receptors. ... Prochlorperazine, also known as compazine, is a piperazine phenothiazine and first-generation antipsychotic …

Peppermint oil

Extracted from the stem, leaves, and flowers of Mentha piperita L. plant, peppermint oil (Mentha piperita) is a popular essential oil used in aromatherapy for both external and internal use. Mentha piperita is a hybrid of spearmint (Mentha spicata) and water mint (Mentha aquatica) . Medicinal use of herbal ingredients...
Approved
Investigational
Matched Description: … and as an anti-itch and cooling agent in topical pharmaceutical products. ... upper respiratory symptoms and cough [A33055]. ... , antibacterial, secretolytic, and choleretic actions [A33056]. …
Matched Categories: … Alimentary Tract and Metabolism ... Herbs and Natural Products …

Dextran

Dextran is a polysaccharide that differs from others in that its glucose units are joined together 1:6 glucoside links. The main chain of glucose has short branches at frequent intervals which are probably joined by 1:3 and 1:4 glucoside links. The chains can be composed of about 200,000 glucose units....
Approved
Investigational
Vet approved
Matched Description: … The main chain of glucose has short branches at frequent intervals which are probably joined by 1:3 and ... [A32011] Many bacteria, like _Leuconostoc_, can synthesize dextran from sucrose, and this activity is ... It is produced from certain bacteria that with α-1,6 glycosidic linkages between glucose molecules and …
Matched Mixtures name: … Redness reliever and Lubricant ... Meijer Advanced Redness and Irritation Relief …
Matched Categories: … Blood and Related Products ... Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions ... Blood Substitutes and Plasma Protein Fractions …

Bordetella pertussis pertactin antigen

Bordetella pertussis pertactin antigen is a vaccine for the prophylaxis of whooping cough that contains pertactin, a membrane-associated antigen of Bordetella pertussis .
Approved
Investigational
Matched Mixtures name: … FILAMENTOUS HEMAGGLUTININ ANTIGEN (FORMALDEHYDE INACTIVATED), BORDETELLA PERTUSSIS PERTACTIN ANTIGEN, and …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Pivampicillin

Pivalate ester analog of ampicillin.
Approved

Ragweed pollen extract

Ragweed pollen extract has been developed by Curalogic. The company has initiated a phase III trial with its product for oral immunotherapy of ragweed allergy. While traditional disease-modifying immunotherapeutics are administered by subcutaneous injection, Curalogic has developed a more convenient orally administered drug.
Approved
Investigational

Eliglustat

Eliglustat is a glucosylceramide synthase inhibitor used for the long-term treatment of type 1 Gaucher disease.[A3752,L41404] Gaucher disease is a rare genetic disorder characterized by the deficiency of acid β-glucosidase, an enzyme that converts glucosylceramide into glucose and ceramide. In patients with Gaucher disease, the accumulation of glucosylceramide leads to...
Approved
Investigational
Matched Description: … [A3752,L41404] Gaucher disease is a rare genetic disorder characterized by the deficiency of acid β-glucosidase ... This leads to complications such as anemia and thrombocytopenia. ... , an enzyme that converts glucosylceramide into glucose and ceramide. …
Matched Categories: … Alimentary Tract and Metabolism ... Various Alimentary Tract and Metabolism Products …

Nesiritide

Nesiritide is a medication used to treat acutely decompensated congestive heart failure with dyspnea at rest or with minimal exertion (such as talk, eating or bathing). Nesiritide is a 32 amino acid recombinant human B-type natriuretic peptide.
Approved
Investigational
Matched Description: … Nesiritide is a 32 amino acid recombinant human B-type natriuretic peptide. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …

Carbon dioxide

Carbon dioxide is a colorless, odorless gas vital to life on Earth. This naturally occurring chemical compound is composed of a carbon atom covalently double bonded to two oxygen atoms. Medical Carbon Dioxide is a liquefied medicinal gas, supplied in cylinders filled to a high pressure. Medical Carbon Dioxide may...
Approved
Investigational
Vet approved
Matched Description: … in solid form (dry ice) for freezing of tissue and removal of warts. ... during bodily investigations, to inflate body cavities during surgery (such as key-hole surgery), and …
Matched Mixtures name: … Carbon Dioxide and Oxygen Mixture, Compressed, Oxidizing, N.O.S. …

Temazepam

Temazepam, like many other similar and related benzodiazepines, acts as a gamma-aminobutyric acid (GABA) modulator and is capable of eliciting a variety of actions including sedation, hypnosis, skeletal muscle relaxation, anticonvulsant activity, and anxiolytic action [A175207, A175210, F3718, F3721]. Although the chemical synthesis of temazepam was established by 1965 ,...
Approved
Investigational
Matched Description: … Temazepam, like many other similar and related benzodiazepines, acts as a gamma-aminobutyric acid (GABA ... capable of developing drug tolerance, physical dependence, and addiction in users. ... relaxation, anticonvulsant activity, and anxiolytic action [A175207, A175210, F3718, F3721]. …
Matched Categories: … Hypnotics and Sedatives ... Benzodiazepine hypnotics and sedatives ... Benzodiazepines and benzodiazepine derivatives …

Tasimelteon

Tasimelteon is a selective dual melatonin receptor agonist indicated for the treatment of Non-24-Hour Sleep-Wake Disorder (N24HSWD). Occurring commonly in blind individuals without light perception, this condition is often characterized by periods of night-time insomnia and day-time sleepiness. In blind individuals, a lack of light stimulation causes an extension of...
Approved
Investigational
Matched Description: … By activating melatonin receptors MT1 and MT2 in the suprachiasmatic nucleus of the brain, tasimelteon ... In blind individuals, a lack of light stimulation causes an extension of the 24-hour circadian cycle and ... Tasimelteon is currently the only drug available for the treatment of N24HSWD and was granted orphan …
Matched Categories: … Hypnotics and Sedatives …
Displaying drugs 1976 - 2000 of 15247 in total