Displaying drugs 2176 - 2200 of 7525 in total
Dazucorilant
Investigational
Matched Synonyms: … (3,4-g)isoquinolin-4a-yl)-2-pyridinyl- ... Methanone, ((4ar)-1-(4-fluorophenyl)-1,4,5,6,7,8-hexahydro-6-((4-(trifluoromethyl)phenyl)sulfonyl)-4ah-pyrazolo …
Matched Iupac: … 2-[(4aR)-1-(4-fluorophenyl)-6-[4-(trifluoromethyl)benzenesulfonyl]-1H,4H,4aH,5H,6H,7H,8H-pyrido[3,4-f …
Matched Iupac: … 2-[(4aR)-1-(4-fluorophenyl)-6-[4-(trifluoromethyl)benzenesulfonyl]-1H,4H,4aH,5H,6H,7H,8H-pyrido[3,4-f …
Ritivixibat
Investigational
Matched Synonyms: … -8-yl]oxy)propanoic acid ... 3-([3,3-dibutyl-7-(methylsulfanyl)-1,1-dioxo-5-phenyl-2,3,4,5-tetrahydro-1H-1Lambda6,2,5-benzothiadiazepin …
Matched Iupac: … -8-yl]oxy}propanoic acid ... 3-{[3,3-dibutyl-7-(methylsulfanyl)-1,1-dioxo-5-phenyl-2,3,4,5-tetrahydro-1lambda6,2,5-benzothiadiazepin …
Matched Iupac: … -8-yl]oxy}propanoic acid ... 3-{[3,3-dibutyl-7-(methylsulfanyl)-1,1-dioxo-5-phenyl-2,3,4,5-tetrahydro-1lambda6,2,5-benzothiadiazepin …
Linerixibat
GSK2330672 has been investigated for the treatment of Diabetes Mellitus, Type 2.
Investigational
Matched Synonyms: … -8-YL)METHYL)AMINO)PENTANEDIOIC ACID ... -BENZOTHIAZEPIN-8-YL)METHYL)AMINO)- ... 3-((((3R,5R)-3-BUTYL-3-ETHYL-7-METHOXY-1,1-DIOXO-5-PHENYL-2,3,4,5-TETRAHYDRO- 1H-1.LAMBDA.6,4-BENZOTHIAZEPIN …
Matched Iupac: … -8-yl]methyl}amino)pentanedioic acid ... 3-({[(3R,5R)-3-butyl-3-ethyl-7-methoxy-1,1-dioxo-5-phenyl-2,3,4,5-tetrahydro-1lambda6,4-benzothiazepin …
Matched Iupac: … -8-yl]methyl}amino)pentanedioic acid ... 3-({[(3R,5R)-3-butyl-3-ethyl-7-methoxy-1,1-dioxo-5-phenyl-2,3,4,5-tetrahydro-1lambda6,4-benzothiazepin …
2-ETHOXYETHYL (2S,3S)-4-((S)-2-BENZYL-3-OXO-4-((3AR,8R,8AS)-2-OXO-3,3A,8,8A-TETRAHYDRO-2H-INDENO[1,2-D]OXAZOL-8-YL)-2,3-DIHYDRO-1H-PYRROL-2-YL)-3-HYDROXY-1-PHENYLBUTAN-2-YLCARBAMATE
Experimental
Matched Name: … D]OXAZOL-8-YL)-2,3-DIHYDRO-1H-PYRROL-2-YL)-3-HYDROXY-1-PHENYLBUTAN-2-YLCARBAMATE ... 2-ETHOXYETHYL (2S,3S)-4-((S)-2-BENZYL-3-OXO-4-((3AR,8R,8AS)-2-OXO-3,3A,8,8A-TETRAHYDRO-2H-INDENO[1,2- …
Matched Iupac: … 2-ethoxyethyl N-[(2S,3S)-4-[(2S)-4-[(3aR,8R,8aS)-2-oxo-2H,3H,3aH,8H,8aH-indeno[1,2-d][1,3]oxazol-8-yl ... ]-2-benzyl-3-oxo-2,3-dihydro-1H-pyrrol-2-yl]-3-hydroxy-1-phenylbutan-2-yl]carbamate …
Matched Iupac: … 2-ethoxyethyl N-[(2S,3S)-4-[(2S)-4-[(3aR,8R,8aS)-2-oxo-2H,3H,3aH,8H,8aH-indeno[1,2-d][1,3]oxazol-8-yl ... ]-2-benzyl-3-oxo-2,3-dihydro-1H-pyrrol-2-yl]-3-hydroxy-1-phenylbutan-2-yl]carbamate …
Soraprazan
Investigational
Matched Synonyms: … ,8r,9r)-7-(2-methoxyethoxy)-2,3-dimethyl-9-phenyl-7,8,9,10-tetrahydroimidazo(1,2-h)(1,7)naphtyridin-8- …
Matched Iupac: … (7R,8R,9R)-7-(2-methoxyethoxy)-2,3-dimethyl-9-phenyl-7H,8H,9H,10H-imidazo[1,2-h]1,7-naphthyridin-8-ol …
Matched Iupac: … (7R,8R,9R)-7-(2-methoxyethoxy)-2,3-dimethyl-9-phenyl-7H,8H,9H,10H-imidazo[1,2-h]1,7-naphthyridin-8-ol …
Eleclazine
Eleclazine has been used in trials studying the treatment of LQT2 Syndrome, Long QT Syndrome, Ischemic Heart Disease, Ventricular Arrhythmia, and Long QT Syndrome Type 3, among others.
Investigational
Matched Synonyms: … 4-(pyrimidin-2-ylmethyl)-7-(4-(trifluoromethoxy)phenyl)-3,4-dihydrobenzo[f][1,4]oxazepin-5(2H)-one …
Matched Iupac: … 4-[(pyrimidin-2-yl)methyl]-7-[4-(trifluoromethoxy)phenyl]-2,3,4,5-tetrahydro-1,4-benzoxazepin-5-one …
Matched Description: … Syndrome, Long QT Syndrome, Ischemic Heart Disease, Ventricular Arrhythmia, and Long QT Syndrome Type 3, …
Matched Iupac: … 4-[(pyrimidin-2-yl)methyl]-7-[4-(trifluoromethoxy)phenyl]-2,3,4,5-tetrahydro-1,4-benzoxazepin-5-one …
Matched Description: … Syndrome, Long QT Syndrome, Ischemic Heart Disease, Ventricular Arrhythmia, and Long QT Syndrome Type 3, …
LAS-191954
Investigational
Matched Synonyms: … 3,4-dihydro-4-oxo-3-phenyl- ... 2-((1s)-1-((6-amino-5-cyano-4-pyrimidinyl)amino)ethyl)-3,4-dihydro-4-oxo-3-phenylpyrrolo(2,1-f)(1,2,4 ... Pyrrolo(2,1-f)(1,2,4)triazine-5-carbonitrile, 2-((1s)-1-((6-amino-5-cyano-4-pyrimidinyl)amino)ethyl)- …
Matched Iupac: … 4-amino-6-{[(1S)-1-{5-cyano-4-oxo-3-phenyl-3H,4H-pyrrolo[2,1-f][1,2,4]triazin-2-yl}ethyl]amino}pyrimidine …
Matched Iupac: … 4-amino-6-{[(1S)-1-{5-cyano-4-oxo-3-phenyl-3H,4H-pyrrolo[2,1-f][1,2,4]triazin-2-yl}ethyl]amino}pyrimidine …
Rodatristat ethyl
Investigational
Matched Synonyms: … 2,8-diazaspiro(4.5)decane-3-carboxylic acid, 8-(2-amino-6-((1r)-1-(5-chloro(1,1'-biphenyl)-2-yl)-2,2,2 ... Ethyl (3s)-8-(2-amino-6-((1r)-1-(5-chloro(1,1'-biphenyl)-2-yl)-2,2,2-trifluoroethoxy)pyrimidin-4-yl)- ... 2,8-diazaspiro(4.5)decane-3-carboxylate …
Matched Iupac: … ethyl (3S)-8-{2-amino-6-[(1R)-1-{5-chloro-[1,1'-biphenyl]-2-yl}-2,2,2-trifluoroethoxy]pyrimidin-4-yl} ... -2,8-diazaspiro[4.5]decane-3-carboxylate …
Matched Iupac: … ethyl (3S)-8-{2-amino-6-[(1R)-1-{5-chloro-[1,1'-biphenyl]-2-yl}-2,2,2-trifluoroethoxy]pyrimidin-4-yl} ... -2,8-diazaspiro[4.5]decane-3-carboxylate …
Gibberellin A4
Experimental
Matched Synonyms: … Gibberellin 4 ... 2β,4a-dihydroxy-1-methyl-8-methylene-4aα,4bβ-gibbane-1α,10β-dicarboxylic acid, 1,4a-lactone …
Hexestrol
A synthetic estrogen that has been used as a hormonal antineoplastic agent.
Withdrawn
Matched Synonyms: … Meso-3,4-di(p-hydroxyphenyl)-n-hexane …
Matched Iupac: … 4-[(3R,4S)-4-(4-hydroxyphenyl)hexan-3-yl]phenol …
Matched Iupac: … 4-[(3R,4S)-4-(4-hydroxyphenyl)hexan-3-yl]phenol …
SB-218078
SB-218078 is a specific inhibitor of CHK1.
Investigational
Matched Synonyms: … 9,10,11,12-tetrahydro-9,12-epoxy-1h-diindolo(1,2,3-fg:3',2',1'-kl)pyrrolo(3,4-i)(1,6)benzodiazocine-1,3 ... 9,12-epoxy-1h-diindolo(1,2,3-fg:3',2',1'-kl)pyrrolo(3,4-i)(1,6)benzodiazocine-1,3(2h)-dione, 9,10,11,12 …
Matched Iupac: … triazaoctacyclo[12.11.2.1^{15,18}.0^{2,6}.0^{7,27}.0^{8,13}.0^{19,26}.0^{20,25}]octacosa-1(26),2(6),7(27),8( …
Matched Iupac: … triazaoctacyclo[12.11.2.1^{15,18}.0^{2,6}.0^{7,27}.0^{8,13}.0^{19,26}.0^{20,25}]octacosa-1(26),2(6),7(27),8( …
LY-3499446
Investigational
Matched Synonyms: … 1-(4-(7-(2-amino-7-fluoro-1,3-benzothiazol-4-yl)-6-chloro-8-fluoro-quinazolin-4-yl)piperazin-1-yl)prop ... 2-propen-1-one, 1-(4-(7-2-amino-7-fluoro-4-benzothiazolyl)-6-chloro-8-fluoro-4-quinazolinyl)-1-piperazinyl …
Vocacapsaicin
Investigational
Matched Synonyms: … 1-piperidinecarboxylic acid, 2-((methylamino)methyl)-, 2-methoxy-4-((((6e)-8-methyl-1-oxo-6-nonen-1-yl ... 2-methoxy-4-(((6e)-8-methylnon-6-enamido)methyl)phenyl (2rs)-2-((methylamino)methyl)piperidine-1-carboxylate …
Matched Iupac: … 2-methoxy-4-{[(6E)-8-methylnon-6-enamido]methyl}phenyl 2-[(methylamino)methyl]piperidine-1-carboxylate …
Matched Iupac: … 2-methoxy-4-{[(6E)-8-methylnon-6-enamido]methyl}phenyl 2-[(methylamino)methyl]piperidine-1-carboxylate …
Tagetitoxin
Tagetitoxin is a bacterial phytotoxin. It preferentially inhibits eukaryotic RNA polymerase.
Experimental
Matched Synonyms: … (1R,4R,5R,6R,7S,8R)-6-Acetoxy-7-amino-4-carbamoyl-4-hydroxy-8-(phosphonooxy)-9-oxa-3-thiabicyclo[3.3.1 …
Matched Iupac: … (1R,4R,5R,6R,7S,8R)-6-(acetyloxy)-7-amino-4-carbamoyl-4-hydroxy-8-(phosphonooxy)-9-oxa-3-thiabicyclo[ …
Matched Iupac: … (1R,4R,5R,6R,7S,8R)-6-(acetyloxy)-7-amino-4-carbamoyl-4-hydroxy-8-(phosphonooxy)-9-oxa-3-thiabicyclo[ …
7-((Carboxy(4-Hydroxyphenyl)Acetyl)Amino)-7-Methoxy-(3-((1-Methyl-1h-Tetrazol-5-Yl)Thio)Methyl)-8-Oxo-5-Oxa-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylic Acid
Experimental
Matched Name: … 7-((Carboxy(4-Hydroxyphenyl)Acetyl)Amino)-7-Methoxy-(3-((1-Methyl-1h-Tetrazol-5-Yl)Thio)Methyl)-8-Oxo …
Matched Iupac: … (6R,7R)-7-[(2R)-2-carboxy-2-(4-hydroxyphenyl)acetamido]-7-methoxy-3-{[(1-methyl-1H-1,2,3,4-tetrazol-5 ... -yl)sulfanyl]methyl}-8-oxo-5-oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Iupac: … (6R,7R)-7-[(2R)-2-carboxy-2-(4-hydroxyphenyl)acetamido]-7-methoxy-3-{[(1-methyl-1H-1,2,3,4-tetrazol-5 ... -yl)sulfanyl]methyl}-8-oxo-5-oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Vebicorvir
Investigational
Matched Synonyms: … (trifluoromethyl)-1,3-thiazol-5-yl)methyl)-10,11-dihydro-5h- 5.lambda.6-dibenzo(b,f)(1,4)thiazepine-8- ... Dibenzo(b,f)(1,4)thiazepine-8-carboxamide, 10,11-dihydro-11-oxo-n-((2-(trifluoromethyl)-5-thiazolyl)methyl …
Tomivosertib
Tomivosertib is under investigation in clinical trial NCT03318562 (A PD Study of Oral eFT508 in Subjects With Advanced TNBC and HCC).
Investigational
Matched Synonyms: … 6'-((6-Amino-4-pyrimidinyl)amino)-8'-methyl-2'H-spiro(cyclohexane-1,3'-imidazo(1,5-a)pyridine)-1',5'- …
Matched Iupac: … 6'-[(6-aminopyrimidin-4-yl)amino]-8'-methyl-2',5'-dihydro-1'H-spiro[cyclohexane-1,3'-imidazo[1,5-a]pyridine …
Matched Salts cas: … 1849590-02-8 …
Matched Iupac: … 6'-[(6-aminopyrimidin-4-yl)amino]-8'-methyl-2',5'-dihydro-1'H-spiro[cyclohexane-1,3'-imidazo[1,5-a]pyridine …
Matched Salts cas: … 1849590-02-8 …
1,3-bis-([3-[3-[3-(4-{3-[3-nitro-5-(galactopyranosyloxy)-benzoylamino]-propyl}-piperazin-1-yl)-propylamino-3,4-dioxo-cyclobutenyl]-amino-propoxy-ethoxy-ethoxy]-propyl-]amino-carbonyloxy)-2-amino-propane
Experimental
Matched Name: … 1,3-bis-([3-[3-[3-(4-{3-[3-nitro-5-(galactopyranosyloxy)-benzoylamino]-propyl}-piperazin-1-yl)-propylamino ... -3,4-dioxo-cyclobutenyl]-amino-propoxy-ethoxy-ethoxy]-propyl-]amino-carbonyloxy)-2-amino-propane …
Matched Iupac: … (Z)-N-[3-(4-{3-[(2-{14-[(E)-[(2-amino-3-{[(E)-{3-[2-(2-{3-[(2-{[3-(4-{3-[(Z)-[hydroxy(3-nitro-5-{[(2R ... trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}phenyl)methylidene]amino]propyl}piperazin-1-yl)propyl]amino}-3,4 ... -C-hydroxycarbonimidoyl]oxy}propoxy)(hydroxy)methylidene]amino]-5,8,11-trioxa-1-azatetradecan-1-yl}-3,4 ... -dioxocyclobut-1-en-1-yl)amino]propyl}piperazin-1-yl)propyl]-3-nitro-5-{[3,4,5-trihydroxy-6-(hydroxymethyl …
Matched Iupac: … (Z)-N-[3-(4-{3-[(2-{14-[(E)-[(2-amino-3-{[(E)-{3-[2-(2-{3-[(2-{[3-(4-{3-[(Z)-[hydroxy(3-nitro-5-{[(2R ... trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}phenyl)methylidene]amino]propyl}piperazin-1-yl)propyl]amino}-3,4 ... -C-hydroxycarbonimidoyl]oxy}propoxy)(hydroxy)methylidene]amino]-5,8,11-trioxa-1-azatetradecan-1-yl}-3,4 ... -dioxocyclobut-1-en-1-yl)amino]propyl}piperazin-1-yl)propyl]-3-nitro-5-{[3,4,5-trihydroxy-6-(hydroxymethyl …
Lirentelimab
Lirentelimab is under investigation in clinical trial NCT04856891 (A Study of Lirentelimab (AK002) in Patients With Active Eosinophilic Duodenitis).
Investigational
Matched Synonyms: … Recombinant humanized, non-fucosylated IgG1 anti-Siglec-8 monoclonal antibody ... IMMUNOGLOBULIN G1-KAPPA, ANTI-(HOMO SAPIENS SIALIC ACID-BINDING IG-LIKE LECTIN 8 (SIALOADHESIN FAMILY ... MEMBER 2, SIGLEC-8, SAF-2))HUMANIZED MOUSE MONOCLONAL ANTIBODY.GAMMA.1 HEAVY CHAIN (1-450) (VH (HOMO …
Inobrodib
Investigational
Matched Synonyms: … (s)-1-(3,4-difluorophenyl)-6-(5-(3,5-dimethylisoxazol-4-yl)-1-((1r,4s)-4-methoxycyclohexyl)-1h-benzo( ... 2-piperidinone, 1-(3,4-difluorophenyl)-6-(5-(3,5-dimethyl-4-isoxazolyl)-1-(trans-4-methoxycyclohexyl) …
Isorhamnetin
Experimental
Matched Synonyms: … 3'-Methoxy-3,4',5,7-tetrahydroxyflavone ... 3-Methylquercetin ... 3-Methylquercetine …
Matched Iupac: … 3,5,7-trihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4H-chromen-4-one …
Matched Iupac: … 3,5,7-trihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4H-chromen-4-one …
Mivavotinib
Investigational
Matched Synonyms: … 6-{[(1r,2s)-2-Aminocyclohexyl]amino}-7-Fluoro-4-(1-Methyl-1h-Pyrazol-4-Yl)-1,2-Dihydro-3h-Pyrrolo[3,4 ... -C]pyridin-3-One …
Matched Iupac: … 6-{[(1R,2S)-2-aminocyclohexyl]amino}-7-fluoro-4-(1-methyl-1H-pyrazol-4-yl)-1H,2H,3H-pyrrolo[3,4-c]pyridin ... -3-one …
Matched Salts cas: … 1952251-28-3 …
Matched Iupac: … 6-{[(1R,2S)-2-aminocyclohexyl]amino}-7-fluoro-4-(1-methyl-1H-pyrazol-4-yl)-1H,2H,3H-pyrrolo[3,4-c]pyridin ... -3-one …
Matched Salts cas: … 1952251-28-3 …
AB-22
Investigational
Matched Synonyms: … N-(2-chloro-6-propoxypyridin-4-yl)-2-(2-hydroxyethyl)-2-(4-isopropyl-1,3-dimethyl-1h-pyrazolo(3,4-b)pyridin ... N-(2-chloro-6-propoxypyridin-4-yl)-2-(2-hydroxyethyl)-2-(4-isopropyl-1,3-dimethyl-1H-pyrazolo[3,4-b]pyridin ... (3,4-b)pyridin-6-yl)-2-(2-hydroxyethyl)- …
Matched Iupac: … 1-(2-chloro-6-propoxypyridin-4-yl)-3-{[1,3-dimethyl-4-(propan-2-yl)-1H-pyrazolo[3,4-b]pyridin-6-yl](2 …
Matched Iupac: … 1-(2-chloro-6-propoxypyridin-4-yl)-3-{[1,3-dimethyl-4-(propan-2-yl)-1H-pyrazolo[3,4-b]pyridin-6-yl](2 …
Dalpiciclib
Investigational
Matched Synonyms: … Pyrido(2,3-d)pyrimidin-7(8h)-one, 6-acetyl-8-cyclopentyl-5-methyl-2-((5-(4-piperidinyl)-2-pyridinyl)amino …
Matched Iupac: … 6-acetyl-8-cyclopentyl-5-methyl-2-{[5-(piperidin-4-yl)pyridin-2-yl]amino}-7H,8H-pyrido[2,3-d]pyrimidin …
Matched Iupac: … 6-acetyl-8-cyclopentyl-5-methyl-2-{[5-(piperidin-4-yl)pyridin-2-yl]amino}-7H,8H-pyrido[2,3-d]pyrimidin …
2-(11-{2-[Benzenesulfonyl-(3-Methyl-Butyl)-Amino]-1-Hydroxy-Ethyl}-6,9-Dioxo-2-Oxa-7,10-Diaza-Bicyclo[11.2.2]Heptadeca-1(16),13(17),14-Trien-8-Yl)-Acetamide, Inhibitor 2
Experimental
Matched Name: … [11.2.2]Heptadeca-1(16),13(17),14-Trien-8-Yl)-Acetamide, Inhibitor 2 ... 2-(11-{2-[Benzenesulfonyl-(3-Methyl-Butyl)-Amino]-1-Hydroxy-Ethyl}-6,9-Dioxo-2-Oxa-7,10-Diaza-Bicyclo …
Matched Iupac: … [11.2.2]heptadeca-1(15),13,16-trien-8-yl]acetamide ... 2-[(8S,11S)-11-[(1R)-1-hydroxy-2-[N-(3-methylbutyl)benzenesulfonamido]ethyl]-6,9-dioxo-2-oxa-7,10-diazabicyclo …
Matched Iupac: … [11.2.2]heptadeca-1(15),13,16-trien-8-yl]acetamide ... 2-[(8S,11S)-11-[(1R)-1-hydroxy-2-[N-(3-methylbutyl)benzenesulfonamido]ethyl]-6,9-dioxo-2-oxa-7,10-diazabicyclo …
Displaying drugs 2176 - 2200 of 7525 in total