Displaying drugs 2176 - 2200 of 2947 in total
Rosuvastatin
Rosuvastatin, also known as the brand name product Crestor, is a lipid-lowering drug that belongs to the statin class of medications, which are used to lower the risk of cardiovascular disease and manage elevated lipid levels by inhibiting the endogenous production of cholesterol in the liver. More specifically, statin medications...
Approved
Matched Synonyms: … fluorophenyl)-6-(1-methylethyl)-2-(ethyl(methylsulfonyl)amino)-5-pyrimidinyl)-3,5-dihydroxy-6-heptenoic acid ... -fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl}-3,5-dihydroxyhept-6-enoic acid …
Matched Iupac: … fluorophenyl)-2-(N-methylmethanesulfonamido)-6-(propan-2-yl)pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid …
Matched Description: … hydroxymethylglutaryl-coenzyme A (HMG-CoA) Reductase,[A181421] which catalyzes the conversion of HMG-CoA to mevalonic acid ... referred to as "bad cholesterol"), and very low-density lipoprotein (VLDL). ... belongs to the statin class of medications, which are used to lower the risk of cardiovascular disease and …
Matched Mixtures name: … Rosuvastatin and Ezetimibe ... Rosuvastatin and Ezetimibe ... Rosuvastatin and Ezetimibe …
Matched Categories: … rosuvastatin and acetylsalicylic acid ... Sulfones ... Agents Causing Muscle Toxicity ... Alimentary Tract and Metabolism ... rosuvastatin and valsartan …
Matched Iupac: … fluorophenyl)-2-(N-methylmethanesulfonamido)-6-(propan-2-yl)pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid …
Matched Description: … hydroxymethylglutaryl-coenzyme A (HMG-CoA) Reductase,[A181421] which catalyzes the conversion of HMG-CoA to mevalonic acid ... referred to as "bad cholesterol"), and very low-density lipoprotein (VLDL). ... belongs to the statin class of medications, which are used to lower the risk of cardiovascular disease and …
Matched Mixtures name: … Rosuvastatin and Ezetimibe ... Rosuvastatin and Ezetimibe ... Rosuvastatin and Ezetimibe …
Matched Categories: … rosuvastatin and acetylsalicylic acid ... Sulfones ... Agents Causing Muscle Toxicity ... Alimentary Tract and Metabolism ... rosuvastatin and valsartan …
Glycol salicylate
Glycol salicylate, also known as 2-hydroxyethyl salicylate, is a benzoate ester formed from the condensation of the carboxy group of salicylic acid with one of the hydroxy groups of ethylene glycol. It is found as an active ingredient and topical analgesic in patches used to provide relief for mild to...
Approved
Matched Synonyms: … 2-hydroxybenzoic acid 2-hydroxyethyl ester …
Matched Description: … to moderate muscle and joint pain [L2686]. ... Glycol salicylate (GS), composed of salicylic acid (SA) and ethylene glycol, is a non-steroidal anti-inflammatory ... pains, and stiffness of the muscles, joints, and tendons [L2696]. …
Matched Mixtures name: … New Ammeltz ... NEW AMMELTZ YOKO YOKO ... NEW AMMELTZ YOKO YOKO GOLD TOPICAL LIQUID …
Matched Categories: … Acids, Carbocyclic ... Hydroxy Acids ... Carboxylic Acids …
Matched Description: … to moderate muscle and joint pain [L2686]. ... Glycol salicylate (GS), composed of salicylic acid (SA) and ethylene glycol, is a non-steroidal anti-inflammatory ... pains, and stiffness of the muscles, joints, and tendons [L2696]. …
Matched Mixtures name: … New Ammeltz ... NEW AMMELTZ YOKO YOKO ... NEW AMMELTZ YOKO YOKO GOLD TOPICAL LIQUID …
Matched Categories: … Acids, Carbocyclic ... Hydroxy Acids ... Carboxylic Acids …
BG-P-TAT
Investigational
Matched Synonyms: … )-(polyethyleneglycol36))-1H-1,2,3-triazol-4-yl)methoxy)-3,5-diiodophenoxy)-3,5-diiodophenyl)acetic acid …
APX-3330
Investigational
Matched Synonyms: … Undecanoic acid, 2-((4,5-dimethoxy-2-methyl-3,6-dioxo-1,4-cyclohexadien-1-yl)methylene)-, (2e)- …
Matched Categories: … Fatty Acids ... Acids, Acyclic ... Carboxylic Acids ... Fatty Acids, Volatile …
Matched Categories: … Fatty Acids ... Acids, Acyclic ... Carboxylic Acids ... Fatty Acids, Volatile …
Iloprost
Iloprost is an analog of prostacyclin (PGI2; epoprostenol), an endogenous prostanoid mainly produced in the vascular endothelium. It is more stable than prostacyclin, which is short-lived. Iloprost consists of a mixture of the 4R and 4S diastereoisomers at a ratio of approximately 53:47. It is a potent vasodilator with reported...
Approved
Investigational
Matched Synonyms: … Hydroxy-4-[(1E)-(3S,4RS)-3-hydroxy-4-methyloct-1-en-6-ynyl]-hexahydropentalen-2(1H)-ylidene]pentanoic acid ... PENTANOIC ACID, 5-((3AS,4R,5R,6AS)-HEXAHYDRO-5-HYDROXY-4-((1E,3S)-3-HYDROXY-4-METHYL-1-OCTEN-6-YNYL)- ... )-hexahydro-5-hydroxy-4-[(E)-(3S,4RS) 3-hydroxy-4-methyl-1-octen-6-ynyl]-Δ2(1H),Δ-pentalenevaleric acid …
Matched Iupac: … 6aS)-5-hydroxy-4-[(1E,3S)-3-hydroxy-4-methyloct-1-en-6-yn-1-yl]-octahydropentalen-2-ylidene]pentanoic acid …
Matched Description: … [A263316] Iloprost is available as an inhaled solution and intravenous formulations. ... It is used to treat pulmonary arterial hypertension (PAH) [L50146] and frostbites.[L50151] ... [A263326] Iloprost consists of a mixture of the 4R and 4S diastereoisomers at a ratio of approximately …
Matched Categories: … Blood and Blood Forming Organs ... Agents Causing Muscle Toxicity ... Fatty Acids ... Fatty Acids, Unsaturated …
Matched Iupac: … 6aS)-5-hydroxy-4-[(1E,3S)-3-hydroxy-4-methyloct-1-en-6-yn-1-yl]-octahydropentalen-2-ylidene]pentanoic acid …
Matched Description: … [A263316] Iloprost is available as an inhaled solution and intravenous formulations. ... It is used to treat pulmonary arterial hypertension (PAH) [L50146] and frostbites.[L50151] ... [A263326] Iloprost consists of a mixture of the 4R and 4S diastereoisomers at a ratio of approximately …
Matched Categories: … Blood and Blood Forming Organs ... Agents Causing Muscle Toxicity ... Fatty Acids ... Fatty Acids, Unsaturated …
Udonitrectag
Investigational
Matched Synonyms: … (1s,4r,5r,7s)-3, 4-dibenzyl-2-oxo-6, 8-dioxa-3-azabicyclo (3.2.1) octane-7-carboxylic acid ... 3, 4-dibenzyl-2-oxo-6, 8-dioxa-3-azabicyclo (3.2.1) octane-7-carboxylic acid, (1s,4r,5r,7s)- ... 6,8-dioxa-3-azabicyclo(3.2.1)octane-7-carboxylic acid, 2-oxo-3,4-bis(phenylmethyl)-, (1s,4r,5r,7s)- …
Matched Iupac: … (1S,4R,5R,7S)-3,4-dibenzyl-2-oxo-6,8-dioxa-3-azabicyclo[3.2.1]octane-7-carboxylic acid …
Matched Iupac: … (1S,4R,5R,7S)-3,4-dibenzyl-2-oxo-6,8-dioxa-3-azabicyclo[3.2.1]octane-7-carboxylic acid …
THIENO[3,2-B]PYRIDINE-2-SULFONIC ACID [2-OXO-1-(1H-PYRROLO[2,3-C]PYRIDIN-2-YLMETHYL)-PYRROLIDIN-3-YL]-AMIDE
Experimental
Matched Name: … THIENO[3,2-B]PYRIDINE-2-SULFONIC ACID [2-OXO-1-(1H-PYRROLO[2,3-C]PYRIDIN-2-YLMETHYL)-PYRROLIDIN-3-YL] …
(S)-2-METHYL-1-[(4-METHYL-5-ISOQUINOLINE)SULFONYL]-HOMOPIPERAZINE
Experimental
Matched Name: … (S)-2-METHYL-1-[(4-METHYL-5-ISOQUINOLINE)SULFONYL]-HOMOPIPERAZINE …
Matched Iupac: … 4-methyl-5-{[(2S)-2-methyl-1,4-diazepan-1-yl]sulfonyl}isoquinoline …
Matched Iupac: … 4-methyl-5-{[(2S)-2-methyl-1,4-diazepan-1-yl]sulfonyl}isoquinoline …
Encaleret
Investigational
Matched Synonyms: … (1,1'-biphenyl)-4-carboxylic acid, 2'-((1r)-1-((2r)-3-((2-(4-chloro-3-fluorophenyl)-1,1-dimethylethyl ... fluorophenyl)-2-methylpropan-2-yl)amino)-2-hydroxypropoxy)ethyl)-3-methyl(1,1'-biphenyl)-4-carboxylic acid ... fluorophenyl)-2-methylpropan-2-yl)amino)-2-hydroxypropyl)oxy)ethyl)-3-methyl-1,1'-biphenyl-4-carboxylic acid …
Matched Iupac: … fluorophenyl)-2-methylpropan-2-yl]amino}-2-hydroxypropoxy]ethyl]-3-methyl-[1,1'-biphenyl]-4-carboxylic acid …
Matched Salts name: … Encaleret sulfate …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids …
Matched Iupac: … fluorophenyl)-2-methylpropan-2-yl]amino}-2-hydroxypropoxy]ethyl]-3-methyl-[1,1'-biphenyl]-4-carboxylic acid …
Matched Salts name: … Encaleret sulfate …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids …
Cidofovir
Cidofovir is an injectable antiviral medication employed in the treatment of cytomegalovirus (CMV) retinitis in patients diagnosed with AIDS. It suppresses CMV replication through selective inhibition of viral DNA synthesis.[FDA label] It was manufactured by Gilead and initially approved by the FDA in 1996, but has since been discontinued.
Approved
Matched Synonyms: … (S)-(3-(4-amino-2-Oxopyrimidin-1(2H)-yl)-1-hydroxypropan-2-yloxy)methylphosphonic acid ... [(S)-2-(4-Amino-2-oxo-2H-pyrimidin-1-yl)-1-hydroxymethyl-ethoxymethyl]-phosphonic acid ... ({[(S)-1-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-3-hydroxypropan-2-yl]oxy}methyl)phosphonic acid …
Matched Iupac: … ({[(2S)-1-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-3-hydroxypropan-2-yl]oxy}methyl)phosphonic acid …
Matched Description: … [FDA label] It was manufactured by _Gilead_ and initially approved by the FDA in 1996, but has since …
Matched Categories: … Nucleosides and Nucleotides ... Nucleosides and Nucleotides Excl. Reverse Transcriptase Inhibitors ... Nucleic Acid Synthesis Inhibitors …
Matched Iupac: … ({[(2S)-1-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-3-hydroxypropan-2-yl]oxy}methyl)phosphonic acid …
Matched Description: … [FDA label] It was manufactured by _Gilead_ and initially approved by the FDA in 1996, but has since …
Matched Categories: … Nucleosides and Nucleotides ... Nucleosides and Nucleotides Excl. Reverse Transcriptase Inhibitors ... Nucleic Acid Synthesis Inhibitors …
OSI-027
OSI-027 has been used in trials studying the treatment of Any Solid Tumor or Lymphoma.
Investigational
Matched Synonyms: … CYCLOHEXANECARBOXYLIC ACID, 4-(4-AMINO-5-(7-METHOXY-1H-INDOL-2-YL)IMIDAZO(5,1-F)(1,2,4)TRIAZIN-7-YL)- …
Matched Iupac: … 4r)-4-[4-amino-5-(7-methoxy-1H-indol-2-yl)imidazo[4,3-f][1,2,4]triazin-7-yl]cyclohexane-1-carboxylic acid …
Matched Iupac: … 4r)-4-[4-amino-5-(7-methoxy-1H-indol-2-yl)imidazo[4,3-f][1,2,4]triazin-7-yl]cyclohexane-1-carboxylic acid …
AV-101
AV-101 has been used in trials studying the treatment of Neuropathic Pain.
Investigational
Matched Synonyms: … (2S)-2-amino-4-(2-amino-4-chlorophenyl)-4-oxobutanoic acid …
Matched Iupac: … (2S)-2-amino-4-(2-amino-4-chlorophenyl)-4-oxobutanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids …
Matched Iupac: … (2S)-2-amino-4-(2-amino-4-chlorophenyl)-4-oxobutanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids …
Ethyl 8-hydroxy-alpha-(2-propynylamino)-5-quinolinepropanoate
Experimental
Matched Synonyms: … 5-Quinolinepropanoic acid, 8-hydroxy-alpha-(2-propyn-1-ylamino)-, ethyl ester …
Norfloxacin
A synthetic fluoroquinolone (fluoroquinolones) with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin inhibits bacterial DNA gyrase.
Approved
Matched Synonyms: … 1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid ... 1,4-Dihydro-1-ethyl-6-fluoro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid …
Matched Iupac: … 1-ethyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid …
Matched Description: … fluoroquinolone (fluoroquinolones) with broad-spectrum antibacterial activity against most gram-negative and …
Matched Categories: … Agents Causing Muscle Toxicity ... norfloxacin and tinidazole ... norfloxacin and metronidazole ... Metabolic Side Effects of Drugs and Substances …
Matched Iupac: … 1-ethyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid …
Matched Description: … fluoroquinolone (fluoroquinolones) with broad-spectrum antibacterial activity against most gram-negative and …
Matched Categories: … Agents Causing Muscle Toxicity ... norfloxacin and tinidazole ... norfloxacin and metronidazole ... Metabolic Side Effects of Drugs and Substances …
Flubendazole
Flubendazole is an anthelmintic that is used to treat worm infection in humans. It is available OTC in Europe.
Experimental
Withdrawn
Matched Synonyms: … (5-(4-fluorobenzoyl)-1H-benzimidazole-2-yl)carbamic acid methyl ester …
Matched Categories: … Antiparasitic Products, Insecticides and Repellents ... Acids, Acyclic ... Carboxylic Acids …
Matched Categories: … Antiparasitic Products, Insecticides and Repellents ... Acids, Acyclic ... Carboxylic Acids …
Pelacarsen
Pelacarsen is under investigation in clinical trial NCT03070782 (Phase 2 Study of ISIS 681257 (Akcea-apo(a)-lrx) in Participants With Hyperlipoproteinemia(a) and Cardiovascular Disease).
Investigational
Matched Synonyms: … Isis-681257 (galnac3--conjugated aso targeting human lipoprotein (a)) free acid …
Matched Description: … NCT03070782 (Phase 2 Study of ISIS 681257 (Akcea-apo(a)-lrx) in Participants With Hyperlipoproteinemia(a) and …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Description: … NCT03070782 (Phase 2 Study of ISIS 681257 (Akcea-apo(a)-lrx) in Participants With Hyperlipoproteinemia(a) and …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Rodatristat
Investigational
Matched Synonyms: … chloro(1,1'-biphenyl)-2-yl)-2,2,2-trifluoroethoxy)-4-pyrimidinyl)-2,8-diazaspiro(4.5)decane-3-carboxylic acid ... 2,8-diazaspiro(4.5)decane-3-carboxylic acid, 8-(2-amino-6-((1r)-1-(5-chloro(1,1'-biphenyl)-2-yl)-2,2,2 ... chloro(1,1'-biphenyl)-2-yl)-2,2,2-trifluoroethoxy)pyrimidin-4-yl)-2,8-diazaspiro(4.5)decane-3-carboxylic acid …
Matched Iupac: … -[1,1'-biphenyl]-2-yl}-2,2,2-trifluoroethoxy]pyrimidin-4-yl}-2,8-diazaspiro[4.5]decane-3-carboxylic acid …
Matched Iupac: … -[1,1'-biphenyl]-2-yl}-2,2,2-trifluoroethoxy]pyrimidin-4-yl}-2,8-diazaspiro[4.5]decane-3-carboxylic acid …
BMS-986278
Investigational
Matched Synonyms: … methyl(propyl)carbamoyl)oxy)methyl)-1h-1,2,3-triazol-4-yl)pyridin-3-yl)oxy)cyclohexane-1-carboxylic acid ... Cyclohexanecarboxylic acid, 3-((2-methyl-6-(1-methyl-5-((((methylpropylamino)carbonyl)oxy)methyl)-1h- …
Matched Iupac: … methyl(propyl)carbamoyl]oxy}methyl)-1H-1,2,3-triazol-4-yl]pyridin-3-yl}oxy)cyclohexane-1-carboxylic acid …
Matched Iupac: … methyl(propyl)carbamoyl]oxy}methyl)-1H-1,2,3-triazol-4-yl]pyridin-3-yl}oxy)cyclohexane-1-carboxylic acid …
Cyclosporine
Cyclosporine is a calcineurin inhibitor known for its immunomodulatory properties that prevent organ transplant rejection and treat various inflammatory and autoimmune conditions. It is isolated from the fungus Beauveria nivea. Initially manufactured by Sandoz and approved for use by the FDA in 1983, cyclosporine is now available in various products...
Approved
Investigational
Vet approved
Matched Description: … treat various inflammatory and autoimmune conditions. ... calcineurin inhibitor known for its immunomodulatory properties that prevent organ transplant rejection and ... [A174049] Initially manufactured by Sandoz and approved for use by the FDA in 1983, cyclosporine is now …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Agents Causing Muscle Toxicity …
Matched Products: … Cyclosporine/Chondroitin Sulfate PF …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Agents Causing Muscle Toxicity …
Matched Products: … Cyclosporine/Chondroitin Sulfate PF …
Guaiacol
Guaiacol is an agent thought to have disinfectant properties and used as an expectorant. Guaiacol is a phenolic natural product first isolated from Guaiac resin and the oxidation of lignin. Guaiacol is also present in wood smoke, as a product of pyrolysis of lignin. Guaiacol has been found in the...
Approved
Matched Synonyms: … Pyroguaiac acid …
Matched Description: … Guaiacol is an agent thought to have disinfectant properties and used as an expectorant. ... Guaiacol has been found in the urine of patients with neuroblastoma and pheochromocytoma. ... Guaiacol is a phenolic natural product first isolated from Guaiac resin and the oxidation of lignin. …
Matched Description: … Guaiacol is an agent thought to have disinfectant properties and used as an expectorant. ... Guaiacol has been found in the urine of patients with neuroblastoma and pheochromocytoma. ... Guaiacol is a phenolic natural product first isolated from Guaiac resin and the oxidation of lignin. …
(6R)-2-amino-6-[2-(3'-methoxybiphenyl-3-yl)ethyl]-3,6-dimethyl-5,6-dihydropyrimidin-4(3H)-one
Experimental
Matched Name: … (6R)-2-amino-6-[2-(3'-methoxybiphenyl-3-yl)ethyl]-3,6-dimethyl-5,6-dihydropyrimidin-4(3H)-one …
Matched Iupac: … (6R)-2-amino-6-(2-{3'-methoxy-[1,1'-biphenyl]-3-yl}ethyl)-3,6-dimethyl-3,4,5,6-tetrahydropyrimidin-4- …
Matched Iupac: … (6R)-2-amino-6-(2-{3'-methoxy-[1,1'-biphenyl]-3-yl}ethyl)-3,6-dimethyl-3,4,5,6-tetrahydropyrimidin-4- …
(4R)-7,8-dichloro-1',9-dimethyl-1-oxo-1,2,4,9-tetrahydrospiro[beta-carboline-3,4'-piperidine]-4-carbonitrile
Experimental
Matched Name: … (4R)-7,8-dichloro-1',9-dimethyl-1-oxo-1,2,4,9-tetrahydrospiro[beta-carboline-3,4'-piperidine]-4-carbonitrile …
Matched Iupac: … (4'R)-7',8'-dichloro-1,9'-dimethyl-1'-oxo-1',2',4',9'-tetrahydrospiro[piperidine-4,3'-pyrido[3,4-b]indole …
Matched Iupac: … (4'R)-7',8'-dichloro-1,9'-dimethyl-1'-oxo-1',2',4',9'-tetrahydrospiro[piperidine-4,3'-pyrido[3,4-b]indole …
S-[2-({N-[(2S)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] hexanethioate
Experimental
Matched Name: … S-[2-({N-[(2S)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] hexanethioate …
Matched Iupac: … [(2-{[2-(hexanoylsulfanyl)ethyl]carbamoyl}ethyl)carbamoyl]-3-hydroxy-2,2-dimethylpropoxy]phosphonic acid …
Matched Iupac: … [(2-{[2-(hexanoylsulfanyl)ethyl]carbamoyl}ethyl)carbamoyl]-3-hydroxy-2,2-dimethylpropoxy]phosphonic acid …
S-[2-({N-[(2S)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] octanethioate
Experimental
Matched Name: … S-[2-({N-[(2S)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] octanethioate …
Matched Iupac: … acid ... [(3S)-3-hydroxy-2,2-dimethyl-3-[(2-{[2-(octanoylsulfanyl)ethyl]carbamoyl}ethyl)carbamoyl]propoxy]phosphonic …
Matched Iupac: … acid ... [(3S)-3-hydroxy-2,2-dimethyl-3-[(2-{[2-(octanoylsulfanyl)ethyl]carbamoyl}ethyl)carbamoyl]propoxy]phosphonic …
N-(TERT-BUTYL)-3,5-DIMETHYL-N'-[(5-METHYL-2,3-DIHYDRO-1,4-BENZODIOXIN-6-YL)CARBONYL]BENZOHYDRAZIDE
Experimental
Matched Name: … N-(TERT-BUTYL)-3,5-DIMETHYL-N'-[(5-METHYL-2,3-DIHYDRO-1,4-BENZODIOXIN-6-YL)CARBONYL]BENZOHYDRAZIDE …
Displaying drugs 2176 - 2200 of 2947 in total