Displaying drugs 201 - 225 of 284 in total
Erdafitinib
In early April of 2019, the US FDA approved Janssen Pharmaceutical Companies' brand name Balversa (erdafitinib) as the first-ever fibroblast growth factor receptor (FGFR) kinase inhibitor indicated for patients with locally advanced or metastatic urothelial carcinoma, with susceptible FGFR3 or FGFR2 genetic alterations, that has progressed during or following platinum-containing...
Approved
Investigational
Anacaulase
Anacaulase (anacaulase-bcdb) is a mixture of proteolytic enzymes extracted from the stems of pineapple plants (Ananas comosus [L.] Merr.). It is mostly composed (80-95% w/w) of proteins such as stem bromelain, ananain, jacalin-like lectin, bromelain inhibitors, and phytocystatin inhibitor, as well as saccharides, as both free monosaccharides and the N-linked...
Approved
Investigational
Matched Description: … Therefore, enzymatic alternatives such as anacaulase can lead to better clinical outcomes. …
Irinotecan
Irinotecan is a topoisomerase inhibitor used for chemotherapy. It is a water-soluble analogue of camptothecin, which is extracted from the Chinese tree Camptotheca acuminate. The bis-piperidine side chain in the structure of irinotecan bestows enhanced water solubility. As an anticancer drug, irinotecan was first commercially available in Japan in 1994...
Approved
Investigational
Matched Description: … irinotecan and SN-38 mediate antitumor activity by forming a complex with topoisomerase I and blocking its enzymatic …
Idoxuridine
An analog of deoxyuridine that inhibits viral DNA synthesis. The drug is used as an antiviral agent.
Approved
Investigational
Inositol nicotinate
Inositol nicotinate, also known as Inositol hexaniacinate/hexanicotinate or "no-flush niacin", is a niacin ester and vasodilator. It is used in food supplements as a source of niacin (vitamin B3), where hydrolysis of 1 g (1.23 mmol) inositol hexanicotinate yields 0.91 g nicotinic acid and 0.22 g inositol. Niacin exists in...
Approved
Withdrawn
Acalabrutinib
To date, acalabrutinib has been used in trials studying the treatment of B-All, myelofibrosis, ovarian cancer, multiple myeloma, and Hodgkin lymphoma, among others.
As of October 31, 2017 the FDA approved Astra Zeneca's orally administered Calquence (acalabrutinib, capsules). This Bruton tyrosine kinase (BTK) inhibitor indicated for the treatment of chronic...
Approved
Investigational
Oxaliplatin
Oxaliplatin is a platinum-based chemotherapy drug in the same family as cisplatin and carboplatin. Compared to cisplatin the two amine groups are replaced by diamino cyclohexane (DACH) group to provide a greater antitumor effect. However, this leads to poorer water solubility, which was compensated by the addition of the chloride...
Approved
Investigational
Matched Description: … [A797] Due to this chemical moiety, oxaliplatin readily undergoes non-enzymatic biotransformation, thus …
Moxisylyte
Moxisylyte, denominated as thymoxamine in the UK, is a specific and orally active α1-adrenergic antagonist. According to the WHO, moxisylyte is approved since 1987 and in the same year, it acquired the denomination of orphan product by the FDA. This drug was developed by the Japanese company Fujirebio and also...
Approved
Investigational
Avobenzone
Avobenzone is dibenzoyl methane derivative. It is oil soluble ingredient. Avobenzone has the ability to absorb ultraviolet light over wider range of wavelengths. It is included in many commercially available sunscreens which are used as wide spectrum sunscreens. Avobenzone is very sensitive to light, to increase its stability and duration...
Approved
Investigational
Matched Mixtures name: … DT Collagen ... Biorlx Lip Balm Collagen ... Vegan Collagen Every Day …
Enalapril
Enalapril is a prodrug belonging to the angiotensin-converting enzyme (ACE) inhibitor drug class that works on the renin-angiotensin-aldosterone system, which is responsible for the regulation of blood pressure and fluid and electrolyte homeostasis. Enalapril is an orally-active and long-acting nonsulphydryl antihypertensive agent that suppresses the renin-angiotensin-aldosterone system to lower blood...
Approved
Vet approved
Somatrem
Despite the ability of almost all contemporary recombinant growth hormones to cause definite and demonstrable increases in growth rate in patients who are administered the drug, the use of these agents continues to be mired in persistent bioethical debate . Such discussion revolves around whether patients' natural disposition of short...
Approved
Investigational
Withdrawn
Velpatasvir
Velpatasvir is a Direct-Acting Antiviral (DAA) medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most common...
Approved
Investigational
Matched Description: … Velpatasvir acts as a defective substrate for NS5A (Non-Structural Protein 5A), a non-enzymatic viral …
Tramadol
Tramadol is a centrally acting synthetic opioid analgesic and SNRI (serotonin/norepinephrine reuptake-inhibitor) that is structurally related to codeine and morphine. Due to its good tolerability profile and multimodal mechanism of action, tramadol is generally considered a lower-risk opioid option for the treatment of moderate to severe pain. It is considered...
Approved
Investigational
Heparin, bovine
Heparin, bovine is under investigation in clinical trial NCT01072747 (Efficacy And Safety Of Unfractionated Heparin In Patients With Cardiovascular Surgery Using Cardiopulmonary Bypass).
Investigational
Matched Synonyms: … BOVINE HEPARIN …
Matched Name: … Heparin, bovine …
Matched Description: … Heparin, bovine is under investigation in clinical trial NCT01072747 (Efficacy And Safety Of Unfractionated …
Matched Name: … Heparin, bovine …
Matched Description: … Heparin, bovine is under investigation in clinical trial NCT01072747 (Efficacy And Safety Of Unfractionated …
Pegylated carboxyhemoglobin (bovine)
Investigational
Matched Name: … Pegylated carboxyhemoglobin (bovine) …
Marine collagen, soluble
Marine collagen, soluble is an animal extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Synonyms: … Collagen,soluble ... Collagen, Soluble, Fish Skin ... Fish Skin Collagen, Soluble …
Matched Name: … Marine collagen, soluble …
Matched Description: … Marine collagen, soluble is an animal extract used in some OTC (over-the-counter) products. …
Matched Mixtures name: … Collagen Boost Cream ... Total Image Collagen Plus ... Highprime Collagen Film …
Matched Products: … Ramosu Collagen Ampoule 200 ... Nova Collagen Oral Powder ... Total Image Collagen Tablet …
Matched Name: … Marine collagen, soluble …
Matched Description: … Marine collagen, soluble is an animal extract used in some OTC (over-the-counter) products. …
Matched Mixtures name: … Collagen Boost Cream ... Total Image Collagen Plus ... Highprime Collagen Film …
Matched Products: … Ramosu Collagen Ampoule 200 ... Nova Collagen Oral Powder ... Total Image Collagen Tablet …
Collagen-polyvinylpyrrolidone
Collagen-polyvinylpyrrolidone is a copolymer generated from a mixture of type I collagen and low-molecular-weight PVP that has undergone γ irradiation . It is characterized by antifibrotic, fibrolytic, and immunomodulatory properties .
Investigational
Matched Name: … Collagen-polyvinylpyrrolidone …
Matched Description: … Collagen-polyvinylpyrrolidone is a copolymer generated from a mixture of type I collagen and low-molecular-weight …
Matched Description: … Collagen-polyvinylpyrrolidone is a copolymer generated from a mixture of type I collagen and low-molecular-weight …
Fibrinolysin
Fibrinolysin consists of two polypeptide chains, one light and one heavy, linked by a disulfide bond. The light chain has a molecular weight of approximately 27,000 Da and contains the active center of Fibrinolysin; the heavy chain has a molecular weight of approximately 57,000 Da. Fibrinolysin is used as a...
Investigational
Matched Synonyms: … Bovine Plasmin ... Plasmin bovine ... Bovine Fibrinolysin …
Matched Description: … a local healing ointment when combined together with the enzyme deoxyribonuclease I (extracted from bovine …
Matched Description: … a local healing ointment when combined together with the enzyme deoxyribonuclease I (extracted from bovine …
Recombinant human type VII collagen
Investigational
Matched Name: … Recombinant human type VII collagen …
Cryptosporidium immune globulin
Investigational
Matched Synonyms: … Cryptosporidium hyperimmune bovine colostrum IgG ... Bovine immunoglobulin concentrate, cryptosporidium parvum ... Bovine anti-cryptosporidium hyperimmune colostrum immunoglobulin …
Lactoferrin
Lactoferrin is under investigation in clinical trial NCT03748043 (The Effectiveness of Lactoferrin in Treatment of Iron Deficiency Anemia in Children With Chronic Tonsillitis).
Investigational
Matched Synonyms: … Lactoferrin (Bovine) …
Orgotein
Superoxide is a natural byproduct of oxygen metabolism which, if left unchecked, leads to cell damage. Superoxide dismutase (SOD) is an enzyme that alternately catalyzes the dismutation of the superoxide radical into either the less damaging hydrogen peroxide or molecular oxygen. Hydrogen peroxide can be degraded by catalase. The antioxidant...
Investigational
Vet approved
Matched Synonyms: … Superoxide dismutase (bovine) …
Displaying drugs 201 - 225 of 284 in total