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Displaying drugs 201 - 225 of 14493 in total

Alglucosidase alfa

Aglucosidase alfa consists of the human enzyme acid alpha-glucosidase (GAA) which is essential for the degradation of glygogen to glucose in lysosomes. It is encoded by the most predominant of nine observed haplotypes of this gene. Aglucosidase alfa is produced by recombinant DNA technology in a Chinese hamster ovary cell...
Approved
Matched Description: … It is used for the treatment of Pompe disease (GAA deficiency) in infants and pediatric patients. ... glycoprotein with a calculated mass of 98,008 daltons for the 883 residue mature polypeptide chain, and ... Alglucosidase alfa degrades glycogen by catalyzing the hydrolysis of a-1,4- and a-1,6- glycosidic linkages …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism …

Andexanet alfa

Andexanet alfa is a recombinant human coagulation Factor Xa that promotes blood coagulation. It was developed by Portola Pharmaceuticals and was approved in in May 2018. It is marketed as Andexxa for intravenous injection or infusion and is indicated for the reversal of anticoagulation in combination with rivaroxaban and apixaban...
Approved
Investigational
Matched Description: … It was developed by Portola Pharmaceuticals and was approved in in May 2018. ... clotting is unfavourable, such as in deep vein thrombosis and pulmonary embolism. ... It is marketed as Andexxa for intravenous injection or infusion and is indicated for the reversal of …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins …

Probenecid

The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy.
Approved
Investigational
Matched Description: … It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. ... Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal …
Matched Mixtures name: … Probenecid and Colchicine ... Probenecid and Colchicine ... Probenecid and Colchicine …
Matched Categories: … colchicine and probenecid ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …

Colfosceril palmitate

Colfosceril palmitate is a synthetic pulmonary surfactant administered in infants with respiratory distress syndrome. It was part of the first generation of commercially available artificial surfactants. It was developed by Burroughs Wellcome and it was FDA approved on August 6, 1990. Nowadays colfosceril palmitate is under the state of canceled...
Approved
Investigational
Withdrawn
Matched Description: … [T70] It was developed by Burroughs Wellcome and it was FDA approved on August 6, 1990. …

DL-dimyristoylphosphatidylcholine

A synthetic phospholipid used in liposomes and lipid bilayers for the study of biological membranes. It is used in commercial drug preparations to solubilize drugs for injection
Approved
Matched Description: … A synthetic phospholipid used in liposomes and lipid bilayers for the study of biological membranes. …
Matched Categories: … Indicators and Reagents …

Thiamine

Thiamine or thiamin, also known as vitamin B1, is a colorless compound with the chemical formula C12H17N4OS. It is soluble in water and insoluble in alcohol. Thiamine decomposes if heated. Thiamine was first discovered by Umetaro Suzuki in Japan when researching how rice bran cured patients of Beriberi. Thiamine plays...
Approved
Investigational
Nutraceutical
Vet approved
Matched Description: … and the nervous and digestive systems. ... It is essential for normal growth and development and helps to maintain proper functioning of the heart ... It is soluble in water and insoluble in alcohol. Thiamine decomposes if heated. …
Matched Mixtures name: … Somarexin and C 1000 ... Multi Vitamin and Mineral vitamin ... Multi Vitamin and Fluoride …
Matched Categories: … Diet, Food, and Nutrition ... Alimentary Tract and Metabolism …

Brilliant blue G

Brilliant Blue G is used in an ophthalmic solution for staining the internal limiting membrane (ILM) of the eye during ophthalmic procedures.[A188841,A188844] This membrane is thin and translucent, making it difficult to identify during eye surgeries that require high levels of visual accuracy. Brilliant blue G, like its name, imparts...
Approved
Matched Iupac: … sodium 3-({[4-({4-[(4-ethoxyphenyl)amino]phenyl}[(1E,4E)-4-{ethyl[(3-sulfonatophenyl)methyl]iminiumyl …
Matched Description: … [A188841,A188844] This membrane is thin and translucent, making it difficult to identify during eye surgeries …
Matched Categories: … Indicators and Reagents …

gamma-Hydroxybutyric acid

Gamma hydroxybutyric acid, commonly abbreviated GHB, is a therapeutic drug which is illegal in multiple countries. It is currently regulated in the US and sold by Jazz Pharmaceuticals under the name Xyrem. However, it is important to note that GHB is a designated Orphan drug (in 1985). Today Xyrem is...
Approved
Illicit
Investigational
Matched Description: … It is currently regulated in the US and sold by Jazz Pharmaceuticals under the name Xyrem. ... Today Xyrem is a Schedule III drug; however GHB remains a Schedule I drug and the illicit use of Xyrem ... naturally occurring substance found in the central nervous system, wine, beef, small citrus fruits and …

Levobupivacaine

Levobupivacaine is an amino-amide local anaesthetic drug belonging to the family of n-alkylsubstituted pipecoloxylidide. It is the S-enantiomer of bupivacaine. Levobupivacaine hydrochloride is commonly marketed by AstraZeneca under the trade name Chirocaine. In particular, the specific levobupivacaine enantiomer is a worthwhile pursuit because it demonstrates less vasodilation and possesses a...
Approved
Investigational
Matched Description: … intrathecal anaesthesia in adults; and infiltration analgesia in children. ... specific levobupivacaine enantiomer is a worthwhile pursuit because it demonstrates less vasodilation and ... predominantly associated with inappropriate administration methods that may cause systemic exposure and …

Sonidegib

Sonidegib is a Hedgehog signaling pathway inhibitor (via smoothened antagonism) developed as an anticancer agent by Novartis. It was FDA approved in 2015 for the treatment of basal cell carcinoma.
Approved
Investigational
Matched Salts name: … Sonidegib phosphate …
Matched Categories: … Antineoplastic and Immunomodulating Agents …

Etoposide

A semisynthetic derivative of podophyllotoxin that exhibits antitumor activity. Etoposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA. This complex induces breaks in double stranded DNA and prevents repair by topoisomerase II binding. Accumulated breaks in DNA prevent entry into the mitotic phase of cell division,...
Approved
Matched Description: … Etoposide acts primarily in the G2 and S phases of the cell cycle. ... Etoposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA. ... This complex induces breaks in double stranded DNA and prevents repair by topoisomerase II binding. …
Matched Salts name: … Etoposide phosphate …
Matched Categories: … Antineoplastic and Immunomodulating Agents …

Calcium polycarbophil

Calcium polycarbophil is a stool stabilizer. Based on its chemical structure, it is a synthetic polymer of polyacrylic acid cross-linked with divinyl glycol presenting a calcium atom as a counter-ion. Polycarbophil is used to treat constipation. This drug may also be used to help relieve the symptoms of irritable bowel...
Approved
Matched Description: … Less gas and bloating compared to psyllium laxative products, but can cause heartburn, and belly cramps ... It is insoluble in water, dilute acids, and dilute alkali. ... digestive enzymes or intestinal absorption, possesses satisfactory stability, is physiologically inert, and …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … Up and Up Fiber Therapy ... Foster and Thrive Fiber Laxative 147 …

Hydrogen peroxide

Hydrogen peroxide is the simplest peroxide with a chemical formula H2O2. Hydrogen peroxide is an unstable compound in the presence of a base or catalyst, and is typically stored with a stabilizer in a weakly acidic solution. If heated to its boiling point, it may undergo potentially explosive thermal decomposition....
Approved
Vet approved
Matched Description: … whites, and dried egg yolks. ... cheese products, and as an oxidizing and reducing agent in products containing dried eggs, dried egg ... and gas form for preservative, disinfection and sterilization applications as an oxidative biocide [A32369 …
Matched Mixtures name: … Prevention Wound and Burn ... QCare Oral Cleansing and Suctioning System, Q4 ... Oral Cleansing and Suctioning System, q2 …
Matched Categories: … Alimentary Tract and Metabolism ... Antiseptics and Disinfectants ... Antiinfectives and Antiseptics for Local Oral Treatment …
Matched Products: … Up and Up 3 Hydrogen Peroxide Wipes ... Multi Purpose Sanitizer and Cleaner Wipes ... QCare Oral Cleansing and Suctioning System …

Quahog, unspecified

Quahog, unspecified allergenic extract is used in allergenic testing.
Approved
Matched Products: … Food - Fish and Shellfish, Clam …

Desmopressin

Desmopressin (dDAVP), a synthetic analogue of 8-arginine vasopressin (ADH), is an antidiuretic peptide drug modified by deamination of 1-cysteine and substitution of 8-L-arginine by 8-D-arginine. ADH is an endogenous pituitary hormone that has a crucial role in the control of the water content in the body. Upon release from the...
Approved
Matched Description: … solution, intravenous solution, oral tablet and oral lyophilisate [A31662]. ... a prolonged half-life and duration of action compared to endogenous ADH [A31661]. ... 8-arginine vasopressin (ADH), is an antidiuretic peptide drug modified by deamination of 1-cysteine and …
Matched Salts name: … Desmopressin acetate anhydrous …
Matched Categories: … Pituitary and Hypothalamic Hormones and Analogues ... Sex Hormones and Insulins ... Vasopressin and Analogues ... Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …

Leniolisib

Leniolisib is a potent and selective inhibitor of phosphoinositide 3-kinase δ (PI3Kδ). The FDA approved leniolisib on March 24, 2023, making it the first treatment for activated phosphoinositide 3-kinase delta syndrome (APDS). APDS is a primary immunodeficiency caused by mutations in genes encoding the PI3Kδ, thereby increasing the activity of...
Approved
Investigational
Matched Description: … Leniolisib is a potent and selective inhibitor of phosphoinositide 3-kinase δ (PI3Kδ). ... in genes encoding the PI3Kδ, thereby increasing the activity of PI3Kδ, causing immune dysfunction, and …
Matched Salts name: … Leniolisib phosphate …
Matched Categories: … Antineoplastic and Immunomodulating Agents …

Crab leg

Crab leg allergenic extract is used in allergenic testing.
Approved
Matched Products: … Food - Fish and Shellfish, Crab Xiphosurus sowerbyi …

Cytisus scoparius flowering top

Cytisus scoparius flowering top allergenic extract is used in allergenic testing.
Approved
Matched Products: … Pollens - Weeds and Garden Plants, Scotch Broom Cytisus scoparius …

Salmon, unspecified

Salmon, unspecified allergenic extract is used in allergenic testing.
Approved
Matched Products: … Food - Fish and Shellfish, Salmon Salmo salar …

Poultry

Poultry allergenic extract is used in allergenic testing.
Approved
Matched Products: … Food - Animal Products and Poultry Products, Chicken Meat Gallus sp. …

Mus musculus skin

Mus musculus skin or pelt is used in allergenic testing.
Approved
Matched Products: … Mouse Hair and Epithelia …

Shrimp

Shrimp allergenic extract is used in allergenic testing.
Approved
Matched Products: … Food - Fish and Shellfish, Shrimp Crago sp. …

Epidermophyton floccosum

Epidermophyton floccosum is a fungus which can provoke allergic reactions. Epidermophyton floccosum extract is used in allergenic testing.
Approved
Matched Products: … Molds, Rusts and Smuts, Epidermophyton floccosum …

Vibrio cholerae CVD 103-HgR strain live antigen

Vibrio cholerae CVD 103-HgR strain live antigen is a component of Vaxchora, an oral vaccine for immunization against Vibrio cholerae serogroup O1. Cholera is an acute bacterial disease of the small intestine caused by Vibrio cholerae, which is gram-negative bacteria. Two serogroups of V. cholerae, O1 and O139, are causative...
Approved
Investigational
Matched Description: … [L39729] It is indicated for individuals aged two years and older.[L12801] ... Two serogroups of _V. cholerae_, O1 and O139, are causative agents of epidemic cholera. ... public health problem that mainly affects countries with limited access to clean water, poor hygiene, and …
Matched Products: … Cholera Vaccine Strain 35a-and 41 8000m/cc …

Odevixibat

Odevixibat, or A4250, is an ileal sodium/bile acid cotransporter inhibitor indicated for the treatment of pruritus in patients older than 3 months, with progressive familial intrahepatic cholestasis (PFIC).[A236808,L34793] Odevixibat is the first approved non-surgical treatment option for PFIC. Previous therapies for PFIC included a bile acid sequestrant such as ursodeoxycholic...
Approved
Investigational
Matched Description: … [A236808] Odevixibat was granted FDA and Health Canada approval on 20 July 2021 and 13 November 2023 ... Odevixibat, or A4250, is an ileal sodium/bile acid cotransporter inhibitor indicated for the treatment …
Matched Categories: … Bile and Liver Therapy ... Alimentary Tract and Metabolism …
Displaying drugs 201 - 225 of 14493 in total