Displaying drugs 2226 - 2250 of 2971 in total
AdPEDF
AdPEDF is under development for the treatment of wet age-related macular degeneration (AMD). It has been shown to rapidly elevate the intraocular AdPEDF protein levels in the eye, inhibit abnormal blood vessel growth, and cause abnormal blood vessels to regress while protecting the eye’s photoreceptors.
Investigational
AVX-470
AVX-470 is an anti-tumor necrosis factor (TNF) polyclonal antibody (bovine).
Investigational
Matched Description: … AVX-470 is an anti-tumor necrosis factor (TNF) polyclonal antibody (bovine). …
EI-1071
EI-1071 is a selective Colony Stimulating Factor-1 Receptor kinase inhibitor.
Investigational
Matched Description: … EI-1071 is a selective Colony Stimulating Factor-1 Receptor kinase inhibitor. …
Dersalazine
Investigational
Matched Categories: … Platelet Activating Factor, antagonists & inhibitors …
Tabalumab
Tabalumab has been used in trials studying the treatment of Autoimmune Disease, Rheumatoid Arthritis, Kidney Failure, Chronic, Connective Tissue Disease, and Systemic Lupus Erythematosus, among others.
Investigational
Matched Categories: … B-Cell Activating Factor, antagonists & inhibitors …
LY-2874455
LY2874455 has been used in trials studying the treatment of Advanced Cancer.
Investigational
Matched Categories: … Receptors, Fibroblast Growth Factor, antagonists & inhibitors …
Debamestrocel
Debamestrocel consists of autologous mesenchymal stromal cells secreting neurotrophic factors. Debamestrocel is under clinical development by BrainStorm Cell Therapeutics and is being investigated for the treatment of Amyotrophic Lateral Sclerosis (ALS).
Investigational
BLZ-945
Investigational
Matched Categories: … Receptor, Macrophage Colony-Stimulating Factor, antagonists & inhibitors …
PD-168393
PD-168393 is an epidermal growth factor receptor inhibitor.
Experimental
Matched Description: … PD-168393 is an epidermal growth factor receptor inhibitor. …
Avotermin
Juvista has been investigated for the treatment, prevention, and basic science of Scars, Keloid, and Cicatrix.
Investigational
Matched Categories: … Transforming Growth Factor beta …
KIN-3248
KIN-3248 is a small molecule that targets and inhibits oncogenic fibroblast growth factor receptors (FGFRs). It was designed to mainly target FGFR2 and FGFR3 alterations, which act as oncogenic drivers in 10-20% of cholangiocarcinoma and 20-35% of urothelial cancers, respectively. While effective, disease progression may occur 6 to 8 months...
Investigational
Matched Description: … KIN-3248 is a small molecule that targets and inhibits oncogenic fibroblast growth factor receptors ( …
Namilumab
Namilumab has been used in trials studying the treatment of Plaque Psoriasis and Rheumatoid Arthritis.
Investigational
Lazertinib
Lazertinib is under investigation in clinical trial NCT04487080 (A Study of Amivantamab and Lazertinib Combination Therapy Versus Osimertinib in Locally Advanced or Metastatic Non-small Cell Lung Cancer).
Investigational
Matched Categories: … Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors …
Echinacoside
Echinacoside is a phenylethanoid glycoside isolated from Echinacea angustifolia in 1950, and currently being investigated for the treatment of Parkinson's, Alzheimer's, atherosclerosis, osteoporosis, acute colitis, wound treatment, and hepatitis. Echinacoside has demonstrated inhibition of apoptosis in neural cell lines, demonstrating potential for use in the treatment of neurological conditions.
Experimental
Cenicriviroc
Cenicriviroc has been used in trials studying the treatment of HIV-infection/AIDS, AIDS Dementia Complex, Nonalcoholic Steatohepatitis, Human Immunodeficiency Virus, and HIV-1-Associated Cognitive Motor Complex.
Investigational
Matched Description: … , Nonalcoholic Steatohepatitis, Human Immunodeficiency Virus, and HIV-1-Associated Cognitive Motor Complex ... Cenicriviroc has been used in trials studying the treatment of HIV-infection/AIDS, AIDS Dementia Complex …
anti-alpha5Beta1-integrin antibody
Integrins are important adhesion molecules that regulate tumor and endothelial cell survival, proliferation and migration. The integrin alpha5beta1 has been shown to play a critical role during angiogenesis. anti-alpha5beta1 integrin antibody inhibits angiogenesis, including vessel formation induced by vascular endothelial growth factor (VEGF), basic fibroblast growth factor (bFGF), as well...
Investigational
Matched Description: … (VEGF), basic fibroblast growth factor (bFGF), as well as other pro-angiogenic growth factors. ... integrin antibody inhibits angiogenesis, including vessel formation induced by vascular endothelial growth factor …
Biopterin
A natural product that has been considered as a growth factor for some insects. [PubChem]
Experimental
Matched Description: … A natural product that has been considered as a growth factor for some insects. [PubChem] …
GVAX
GVAX is a granulocyte-macrophage colony-stimulating factor (GM-CSF) gene-transfected tumor cell vaccine.
Investigational
Matched Description: … GVAX is a granulocyte-macrophage colony-stimulating factor (GM-CSF) gene-transfected tumor cell vaccine …
TASO-001
TASO-001 is a transforming growth factor (TGF)-beta 2 specific antisense oligodeoxynucleotide.
Investigational
Matched Description: … TASO-001 is a transforming growth factor (TGF)-beta 2 specific antisense oligodeoxynucleotide. …
XTMAB-16
XTMAB-16 is a monoclonal antibody directed against tumour necrosis factor-alpha (TNFα).
Investigational
Matched Description: … XTMAB-16 is a monoclonal antibody directed against tumour necrosis factor-alpha (TNFα). …
Rociletinib
Rociletinib has been used in trials studying the treatment and prevention of Nonsmall Cell Lung Cancer, Non-small Cell Lung Cancer, and Locally Advanced or Metastatic Non-small Cell Lung Cancer.
Investigational
Matched Categories: … Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors …
Dociparstat sodium
Investigational
Zeatin
An aminopurine factor in plant extracts that induces cell division. (Grant & Hackh's Chemical Dict, 5th ed)
Experimental
Matched Description: … An aminopurine factor in plant extracts that induces cell division. …
Tildacerfont
Tildacerfont is a corticotropin-releasing factor receptor-1 antagonist containing an unfused thiazole ring
Investigational
Matched Description: … Tildacerfont is a corticotropin-releasing factor receptor-1 antagonist containing an unfused thiazole …
Irpagratinib
Irpagratinib (ABSK011) is a highly selective inhibitor of fibroblast growth factor receptor (FGFR) 4.
Investigational
Matched Description: … Irpagratinib (ABSK011) is a highly selective inhibitor of fibroblast growth factor receptor (FGFR) 4. …
Displaying drugs 2226 - 2250 of 2971 in total