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Displaying drugs 2251 - 2275 of 2498 in total
GW 468816
GW 468816 is glycine receptor antagonist. It is designed to aid abstinence in people who have just quit smoking, delaying the time to relapse. It was undergoing phase II trials since December 2003.
Investigational
Matched Categories: … Receptors, N-Methyl-D-Aspartate, antagonists & inhibitors …
Famitinib
Famitinib has been used in trials studying the treatment of Colorectal Cancer, Renal Cell Cancer, Colorectal Cancer Recurrent, Colorectal Cancer Metastatic, and Metastatic Renal Cell Cancer, among others.
Investigational
Matched Categories: … Receptor Protein-Tyrosine Kinases, antagonists & inhibitors …
Ronopterin
Ronopterin has been used in trials studying the treatment of Traumatic Brain Injury.
Investigational
Matched Categories: … Nitric Oxide Synthase, antagonists & inhibitors …
XL-888
XL888 has been used in trials studying the treatment of Cancer and Melanoma.
Investigational
Matched Categories: … HSP90 Heat-Shock Proteins, antagonists & inhibitors …
Tyrosinase
Tyrosinase is a multi-copper-containing multifunctional metalloenzyme with 4 possible oxidation states.[A231829, A231834, A231839] It is responsible for producing melanin pigment across the phylogenetic spectrum.[A231829, A231834, A231839]
Within mammals, tyrosinase is found specifically in melanocytes in a glycosylated form and plays a critical role in regulating the process of melanin biosynthesis...
Investigational
Matched Categories: … Monophenol Monooxygenase, antagonists & inhibitors …
Glyceraldehyde-3-Phosphate Dehydrogenase
Investigational
Matched Categories: … Glyceraldehyde-3-Phosphate Dehydrogenases, antagonists & inhibitors …
Hydracarbazine
Hydracarbazine is a pyridazine that has found use as an antihypertensive agent It was once marketed in France under the tradename Normatensyl.
Experimental
Matched Categories: … Monoamine Oxidase Inhibitors …
Octamoxin
Octamoxin, also known as 2-octylhydrazine, is both an irreversible and nonselective monoamine oxidase enzyme inhibitor (MAOI) of the hydrazine chemical class. This drug was used in the past as an antidepressant agent in the 1960s, however, has since been discontinued.
Withdrawn
Matched Categories: … Monoamine Oxidase Inhibitors …
TAK-901
TAK-901 has been used in trials studying the treatment of Lymphoma, Myelofibrosis, Multiple Myeloma, Myeloid Metaplasia, and Advanced Solid Tumors, among others.
Investigational
Matched Categories: … Protein Kinase Inhibitors …
Spartalizumab
Spartalizumab is under investigation in clinical trial NCT02605967 (Safety and Efficacy Study of PDR001 in Patients With Recurrent or Metastatic Nasopharyngeal Carcinoma).
Investigational
Matched Categories: … Immune Checkpoint Inhibitors …
3-Bromo-7-Nitroindazole
Experimental
Matched Categories: … Nitric Oxide Synthase, antagonists & inhibitors …
Calcitonin gene-related peptide
A 37-amino acid peptide derived from the calcitonin gene. It occurs as a result of alternative processing of mRNA from the calcitonin gene. The neuropeptide is widely distributed in the brain, gut, perivascular nerves, and other tissue. The peptide produces multiple biological effects and has both circulatory and neurotransmitter modes...
Investigational
Matched Categories: … Calcitonin Gene-Related Peptide, antagonists & inhibitors …
Anacetrapib
Investigational
Matched Categories: … Cholesterol Ester Transfer Proteins, antagonists & inhibitors …
Navarixin
Navarixin has been investigated for the treatment of Asthma.
Investigational
Matched Categories: … Receptors, Interleukin-8A, antagonists & inhibitors …
AUY922
AUY922 has been used in trials studying the treatment of Lymphoma, Breast Cancer, Metastatic Disease, Advanced Solid Tumors, and Hematologic Neoplasms, among others.
Investigational
Matched Categories: … HSP90 Heat-Shock Proteins, antagonists & inhibitors …
Pradigastat
Pradigastat has been used in trials studying the treatment of Non-alcoholic Fatty Liver Disease (NAFLD).
Investigational
Matched Categories: … OAT3/SLC22A8 Inhibitors …
QGC-001
QGC001 has been used in trials studying the treatment of Essential Hypertension.
Investigational
Matched Categories: … Glutamyl Aminopeptidase, antagonists & inhibitors …
Displaying drugs 2251 - 2275 of 2498 in total