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Displaying drugs 2326 - 2350 of 3628 in total
Vestronidase alfa, or vestronidase alfa-vjbk, is a recombinant human lysosomal beta glucuronidase that is a purified enzyme produced by recombinant DNA technology in a Chinese hamster ovary cell line. The enzyme is a homotetramer consisted of 4 monomers with 629 amino acids, and holds the same amino acid sequence as...
Approved
Investigational
Matched Synonyms: … Recombinant human beta-glucuronidase …
Matched Description: … The enzyme is a homotetramer consisted of 4 monomers with 629 amino acids, and holds the same amino acid ... spleen, heart valve abnormalities, and narrowed airways which can lead to lung infections and trouble ... MPS VII is a progressive condition that affects most tissues and organs due to the lack of a lysosomal …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes ... Lysosomal beta Glucuronidase …
Ribaxamase is under investigation in clinical trial NCT02563106 (A Study of SYN-004 for the Prevention of c.diff in Patients With a LRTI).
Investigational
Matched Synonyms: … .beta.-lactamase (synthetic bacillus licheniformis isoenzyme syn-004) …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes …
Experimental
Matched Synonyms: … UDP-4-fluoro-4-deoxy-alpha-D-glucose …
Matched Name: … Uridine-5'-diphosphate-4-deoxy-4-fluoro-alpha-D-galactose …
Matched Iupac: … ,4R,5S,6R)-5-fluoro-3,4-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}(hydroxy)phosphoryl)oxy]phosphinic acid
Approved
Investigational
Matched Synonyms: … alpha-Narcotine …
Matched Salts name: … Noscapine hydrochloride
Matched Categories: … Cough and Cold Preparations ... Opium Alkaloids and Derivatives …
Etafedrine (INN) or ethylephedrine is a long-acting bronchodilator and has been an ingredient combined with other drugs in the brand names Nethaprin and Dalmacol . It was previously available as both the free base and as the hydrochloride salt manufactured by Sanofi-Aventis (now Sanofi) has been discontinued . Ethylephedrine is...
Approved
Matched Synonyms: … alpha-(1-(ethylmethylamino)ethyl)benzyl alcohol …
Matched Description: … It was previously available as both the free base and as the hydrochloride salt manufactured by Sanofi-Aventis ... Etafedrine (INN) or ethylephedrine is a long-acting bronchodilator and has been an ingredient combined ... with other drugs in the brand names Nethaprin [A32757] and Dalmacol [L2568]. …
Matched Salts name: … Etafedrine hydrochloride
Matched Categories: … Adrenergic beta-Agonists ... Adrenergic beta-2 Receptor Agonists …
Experimental
Matched Iupac: … acetamido]-8-oxo-3-[(1H-1,2,3-triazol-4-ylsulfanyl)methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Matched Categories: … Thiazines ... beta-Lactams …
Matched Products: … ZINAF
Experimental
Matched Synonyms: … (2S)-1-((2R)-2-Methyl-3-sulfanylpropanoyl)pyrrolidine-2-carboxylic acid
Matched Iupac: … (2S)-1-[(2R)-2-methyl-3-sulfanylpropanoyl]pyrrolidine-2-carboxylic acid
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Imino Acids ... Amino Acids, Cyclic …
Experimental
Matched Synonyms: … 4-[2-Acetylamino-2-(1-biphenyl-4-ylmethyl-2-oxo-azepan-3-ylcarbamoyl)-ethyl]-2-formyl-benzoic acid
Matched Iupac: … (3S)-1-({[1,1'-biphenyl]-4-yl}methyl)-2-oxoazepan-3-yl]carbamoyl}-2-acetamidoethyl]-2-formylbenzoic acid
Benazepril, brand name Lotensin, is a medication used to treat high blood pressure (hypertension), congestive heart failure, and chronic renal failure[A838,A837]. Upon cleavage of its ester group by the liver, benazepril is converted into its active form benazeprilat, a non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor .
Approved
Investigational
Matched Iupac: … [(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}-2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl]acetic acid
Matched Description: … Lotensin, is a medication used to treat high blood pressure (hypertension), congestive heart failure, and
Matched Mixtures name: … Benazepril Hydrochloride and Hydrochlorothiazide ... Benazepril Hydrochloride and Hydrochlorothiazide ... Benazepril Hydrochloride and Hydrochlorothiazide …
Matched Salts name: … Benazepril hydrochloride
Matched Categories: … ACE Inhibitors and Calcium Channel Blockers ... ACE Inhibitors and Diuretics ... benazepril and amlodipine ... benazepril and diuretics …
Matched Products: … Benazepril Hydrochloride ... Benazepril hydrochloride
Experimental
Matched Synonyms: … 4-Amino-2-deoxy-2,3-dehydro-N-neuraminic acid
Matched Iupac: … (2R,3R,4S)-4-amino-3-acetamido-2-[(1R,2R)-1,2,3-trihydroxypropyl]-3,4-dihydro-2H-pyran-6-carboxylic acid
Investigational
Matched Synonyms: … (S)-2-(6-Methoxy-2-naphthyl)propanoic acid 4-nitrooxybutyl ester …
Matched Categories: … Nitric Oxide Donors ... Naphthaleneacetic Acids ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Approved
Experimental
Matched Synonyms: … Salicyclic acid, ethyl ester …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids ... Hydroxy Acids
PIK-75 is a preferential p110 alpha/gamma PI3K inhibitor.
Investigational
Matched Synonyms: … Benzenesulfonic acid, 2-methyl-5-nitro-, 2-((6-bromoimidazo(1,2-a)pyridin-3-yl)methylene)-1-methylhydrazide …
Matched Description: … PIK-75 is a preferential p110 alpha/gamma PI3K inhibitor.[A253097] …
Investigational
Matched Synonyms: … (1,1'-biphenyl)-3-carboxylic acid, 2'-(aminomethyl)-5'-(((3-fluoro-4-pyridinyl)amino)carbonyl)-, propyl …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids
Doxorubicin is a cytotoxic anthracycline antibiotic isolated from cultures of Streptomyces peucetius var. caesius along side with daunorubicin, another cytotoxic agent, in 1970.[A1575,A257709,A257614] Although they both have aglyconic and sugar moieties, doxorubicin's side chain terminates with a primary alcohol group compared to the methyl group of daunorubicin. Although its detailed...
Approved
Investigational
Matched Description: … [A1575,A257709,A257614] Although they both have aglyconic and sugar moieties, doxorubicin's side chain ... Hodgkin’s lymphoma, multiple myeloma, sarcoma, and pediatric cancers. ... generally thought to exert its effect through DNA intercalation, which eventually leads to DNA damage and
Matched Salts name: … Doxorubicin hydrochloride
Matched Categories: … Anthracyclines and Related Substances ... Antineoplastic and Immunomodulating Agents ... Cytotoxic Antibiotics and Related Substances …
Matched Products: … Doxorubicin Hydrochloride ... DOXOrubicin Hydrochloride ... Doxorubicin hydrochloride
Experimental
Matched Name: … 2-propenyl-N-acetyl-neuramic acid
Matched Iupac: … 5R,6R)-5-acetamido-4-hydroxy-2-(prop-2-en-1-yl)-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylic acid
Experimental
Matched Name: … (R)-2-Hydroxy-3-Sulfopropanoic Acid
Matched Iupac: … (2R)-2-hydroxy-3-sulfopropanoic acid
Experimental
Matched Name: … 3-deoxy-D-lyxo-hexonic acid
Matched Iupac: … (2S,4R,5R)-2,4,5,6-tetrahydroxyhexanoic acid
Experimental
Matched Name: … 2-(3-GUANIDINOPHENYL)-3-MERCAPTOPROPANOIC ACID
Matched Iupac: … (2R)-2-{3-[(diaminomethylidene)amino]phenyl}-3-sulfanylpropanoic acid
Experimental
Matched Name: … 5-(2-CHLOROBENZYL)-2-FUROIC ACID
Matched Iupac: … 5-[(2-chlorophenyl)methyl]furan-2-carboxylic acid
Experimental
Matched Name: … 2-((4'-HYDROXYPHENYL)-AZO)BENZOIC ACID
Matched Iupac: … 2-[(1E)-2-(4-hydroxyphenyl)diazen-1-yl]benzoic acid
Experimental
Matched Name: … 4-(2-HYDROXYPHENYLTHIO)-1-BUTENYLPHOSPHONIC ACID
Matched Iupac: … [(1E)-4-[(2-hydroxyphenyl)sulfanyl]but-1-en-1-yl]phosphonic acid
Experimental
Matched Name: … (2S)-hydroxy(4-hydroxyphenyl)ethanoic acid
Matched Iupac: … (2S)-2-hydroxy-2-(4-hydroxyphenyl)acetic acid
Experimental
Matched Name: … 3-[4-(AMINOSULFONYL)PHENYL]PROPANOIC ACID
Matched Iupac: … 3-(4-sulfamoylphenyl)propanoic acid
Experimental
Matched Name: … 2-((4'-HYDROXYNAPHTHYL)-AZO)BENZOIC ACID
Matched Iupac: … 2-[(1E)-2-(4-hydroxynaphthalen-1-yl)diazen-1-yl]benzoic acid
Displaying drugs 2326 - 2350 of 3628 in total