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Displaying drugs 2401 - 2425 of 3217 in total
Sitafloxacin
Experimental
Investigational
Matched Iupac: … bis(7-[(7S)-7-amino-5-azaspiro[2.4]heptan-5-yl]-8-chloro-6-fluoro-1-[(1R,2S)-2-fluorocyclopropyl]-4-oxo …
Nepicastat
Nepicastat has been investigated for the treatment of Cocaine Dependence and Posttraumatic Stress Disorder.
Investigational
Axalimogene filolisbac
Axalimogene filolisbac is under investigation in clinical trial NCT02853604 (Study of ADXS11-001 in Subjects With High Risk Locally Advanced Cervical Cancer).
Investigational
Arbaclofen Placarbil
Arbaclofen Placerbil is a prodrug of Arbaclofen, which is a selective gamma-amino-butyric acid type B receptor agonist and the R-enantiomer of baclofen. It was discovered, and has been patented by XenoPort as a new chemical entity with an improved pharmacokinetic profile compared to baclofen, which allows for sustained release properties....
Investigational
Coenzyme F420
Experimental
Camsirubicin
GPX-150 has been used in trials studying the treatment of Soft Tissue Sarcoma and Advanced Solid Tumors - Phase 1 Population.
Investigational
Rogaratinib
Rogaratinib is under investigation in clinical trial NCT03762122 (Rogaratinib in Patients With Advanced Pretreated Squamous-cell Non-small Cell Lung Cancer (SQCLC)).
Investigational
Matched Iupac: … -7-yl]methyl}piperazin-2-one ... 4-{[4-amino-5-(7-methoxy-5-methyl-1-benzothiophen-2-yl)-6-(methoxymethyl)pyrrolo[2,1-f][1,2,4]triazin …
Narsoplimab
Thrombotic microangiopathies (TMA), including thrombotic thrombocytopenic purpura and atypical hemolytic uremic syndrome, are associated with injury and dysregulation of microvascular endothelium and platelets. Evidence increasingly points to a role for the complement system in TMA.[A241030, A241040] Mannan-associated lectin-binding serine protease-2 (MASP-2) is a major effector in the complement lectin pathway.[A241030,...
Investigational
2,2'-{[9-(HYDROXYIMINO)-9H-FLUORENE-2,7-DIYL]BIS(OXY)}DIACETIC ACID
Experimental
Matched Iupac: … 2-{[7-(carboxymethoxy)-9-(hydroxyimino)-9H-fluoren-2-yl]oxy}acetic acid …
Trapidil
Trapidil, a platelet-derived growth factor antagonist, was originally developed as a vasodilator and anti-platelet agent and has been used to treat patients with ischemic coronary heart, liver, and kidney disease.
Experimental
Matched Iupac: … N,N-diethyl-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine …
Iguratimod
Iguratimod is under investigation in Rheumatoid Arthritis.
Investigational
Matched Iupac: … N-(7-methanesulfonamido-4-oxo-6-phenoxy-4H-chromen-3-yl)formamide …
Deoxyspergualin
Deoxyspergualin has been used in trials studying the treatment of Lupus Nephritis, Chronic Rejection, and Diabetes Mellitus, Type 1.
Investigational
Matched Iupac: … N-[(S)-({4-[(3-aminopropyl)amino]butyl}carbamoyl)(hydroxy)methyl]-7-carbamimidamidoheptanamide …
Chiauranib
Chiauranib is under investigation in clinical trial NCT03974243 (Chiauranib in Combination With Chidamide in Patients With Relapsed/refractory Non-hodgkin's Lymphoma).
Investigational
Matched Iupac: … N-(2-aminophenyl)-6-[(7-methoxyquinolin-4-yl)oxy]naphthalene-1-carboxamide …
CPZEN-45
Investigational
Mixed Carbamic Phosphoric Acid Anhydride of 7,8-Diaminononanic Acid
Experimental
Matched Iupac: … (7R,8S)-8-amino-7-{[(phosphonooxy)carbonyl]amino}nonanoic acid …
Sinefungin
Sinefungin is a solid. This compound belongs to the purine nucleosides and analogues. These are compounds comprising a purine base attached to a sugar. The proteins that adenosyl-ornithine target include RdmB, modification methylase TaqI, rRNA (adenine-N6-)-methyltransferase, and modification methylase RsrI.
Experimental
Zinc mesoporphyrin
Investigational
6-PHENYL[5H]PYRROLO[2,3-B]PYRAZINE
Experimental
Matched Iupac: … 4-{7-butyl-5H-pyrrolo[2,3-b]pyrazin-6-yl}phenol …
Nequinate
Nequinate is an antiprotozoan used as a coccidiostat for poultry and rabbits. Nequinate belongs to the family of Hydroquinolones. These are compounds containing an hydrogenated quinoline bearing a ketone group.
Vet approved
Matched Iupac: … methyl 7-(benzyloxy)-6-butyl-4-oxo-1,4-dihydroquinoline-3-carboxylate …
Pardoprunox
Pardoprunox has been used in trials studying the treatment of Early Stage Parkinson's Disease and Advanced Stage Parkinson's Disease. Pardoprunox is a partial dopamine D2 agonist and noradrenergic agonist with serotonin 5-HT1A agonist properties.
Investigational
Matched Iupac: … 7-(4-methylpiperazin-1-yl)-2,3-dihydro-1,3-benzoxazol-2-one …
Proxyphylline
Experimental
Matched Iupac: … 7-(2-hydroxypropyl)-1,3-dimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione …
Displaying drugs 2401 - 2425 of 3217 in total